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Jamal C. Saeh
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Journal Articles

AZD4320, A Dual Inhibitor of Bcl-2 and Bcl-xL, Induces Tumor Regression in Hematologic Cancer Models without Dose-limiting Thrombocytopenia

Srividya B. Balachander, Steven W. Criscione, Kate F. Byth, Justin Cidado, Ammar Adam, Paula Lewis, Terry Macintyre, Shenghua Wen, Deborah Lawson, Kathleen Burke, Tristan Lubinski, Jeffrey W. Tyner, Stephen E. Kurtz, Shannon K. McWeeney, Jeffrey Varnes, R. Bruce Diebold, Thomas Gero, Stephanos Ioannidis, Edward J. Hennessy, William McCoull, Jamal C. Saeh, Areya Tabatabai, Omid Tavana, Nancy Su, Alwin Schuller, Mathew J. Garnett, Patricia Jaaks, Elizabeth A. Coker, Gareth P. Gregory, Andrea Newbold, Ricky W. Johnstone, Eric Gangl, Martin Wild, Michael Zinda, J. Paul Secrist, Barry R. Davies, Stephen E. Fawell, Francis D. Gibbons
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (24): 6535–6549.
https://doi.org/10.1158/1078-0432.CCR-20-0863
Published: 15 December 2020
View article titled, AZD4320, A Dual Inhibitor of Bcl-2 and Bcl-x<sub>L</sub>, Induces Tumor Regression in Hematologic Cancer Models without Dose-limiting Thrombocytopenia
Open the PDF for AZD4320, A Dual Inhibitor of Bcl-2 and Bcl-x<sub>L</sub>, Induces Tumor Regression in Hematologic Cancer Models without Dose-limiting Thrombocytopenia in another window
Includes: Supplementary data
Journal Articles

AZD4573 Is a Highly Selective CDK9 Inhibitor That Suppresses MCL-1 and Induces Apoptosis in Hematologic Cancer Cells

Justin Cidado, Scott Boiko, Theresa Proia, Douglas Ferguson, Steven W. Criscione, Maryann San Martin, Petar Pop-Damkov, Nancy Su, Valar Nila Roamio Franklin, Chandra Sekhar Reddy Chilamakuri, Clive S. D'Santos, Wenlin Shao, Jamal C. Saeh, Raphael Koch, David M. Weinstock, Michael Zinda, Stephen E. Fawell, Lisa Drew
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (4): 922–934.
https://doi.org/10.1158/1078-0432.CCR-19-1853
Published: 14 February 2020
View article titled, AZD4573 Is a Highly Selective CDK9 Inhibitor That Suppresses MCL-1 and Induces Apoptosis in Hematologic Cancer Cells
Open the PDF for AZD4573 Is a Highly Selective CDK9 Inhibitor That Suppresses MCL-1 and Induces Apoptosis in Hematologic Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Selective Androgen Receptor Modulator RAD140 Inhibits the Growth of Androgen/Estrogen Receptor–Positive Breast Cancer Models with a Distinct Mechanism of Action

Ziyang Yu, Suqin He, Dannie Wang, Hitisha K. Patel, Chris P. Miller, Jeffrey L. Brown, Gary Hattersley, Jamal C. Saeh
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (24): 7608–7620.
https://doi.org/10.1158/1078-0432.CCR-17-0670
Published: 14 December 2017
View article titled, Selective Androgen Receptor Modulator RAD140 Inhibits the Growth of Androgen/Estrogen Receptor–Positive Breast Cancer Models with a Distinct Mechanism of Action
Open the PDF for Selective Androgen Receptor Modulator RAD140 Inhibits the Growth of Androgen/Estrogen Receptor–Positive Breast Cancer Models with a Distinct Mechanism of Action in another window
Includes: Supplementary data