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J. William Harbour
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Journal Articles

Therapeutic Escape in Gαq-mutant Uveal Melanoma: It's a FAK

J. William Harbour
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (11): 2967–2969.
https://doi.org/10.1158/1078-0432.CCR-21-0567
Published: 01 June 2021
View article titled, Therapeutic Escape in Gαq-mutant Uveal Melanoma: It's a FAK
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Journal Articles

HDAC Inhibition Enhances the In Vivo Efficacy of MEK Inhibitor Therapy in Uveal Melanoma

Fernanda Faião-Flores, Michael F. Emmons, Michael A. Durante, Fumi Kinose, Biswarup Saha, Bin Fang, John M. Koomen, Srikumar P. Chellappan, Silvya Stuchi Maria-Engler, Uwe Rix, Jonathan D. Licht, J. William Harbour, Keiran S.M. Smalley
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (18): 5686–5701.
https://doi.org/10.1158/1078-0432.CCR-18-3382
Published: 13 September 2019
View article titled, HDAC Inhibition Enhances the <em>In Vivo</em> Efficacy of MEK Inhibitor Therapy in Uveal Melanoma
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Includes: Supplementary data
Journal Articles

BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas

Matthew G. Field, Jeffim N. Kuznetsov, Parker L. Bussies, Louie Z. Cai, Karam A. Alawa, Christina L. Decatur, Stefan Kurtenbach, J. William Harbour
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (18): 5663–5673.
https://doi.org/10.1158/1078-0432.CCR-19-0366
Published: 13 September 2019
View article titled, BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas
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Includes: Supplementary data
Journal Articles

Integrative Copy Number Analysis of Uveal Melanoma Reveals Novel Candidate Genes Involved in Tumorigenesis Including a Tumor Suppressor Role for PHF10/BAF45a

Hima Anbunathan, Ruth Verstraten, Arun D. Singh, J. William Harbour, Anne M. Bowcock
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (16): 5156–5166.
https://doi.org/10.1158/1078-0432.CCR-18-3052
Published: 15 August 2019
View article titled, Integrative Copy Number Analysis of Uveal Melanoma Reveals Novel Candidate Genes Involved in Tumorigenesis Including a Tumor Suppressor Role for <em>PHF10/BAF45a</em>
Open the PDF for Integrative Copy Number Analysis of Uveal Melanoma Reveals Novel Candidate Genes Involved in Tumorigenesis Including a Tumor Suppressor Role for <em>PHF10/BAF45a</em> in another window
Includes: Supplementary data
Journal Articles

PRAME as an Independent Biomarker for Metastasis in Uveal Melanoma

Matthew G. Field, Christina L. Decatur, Stefan Kurtenbach, Gülçin Gezgin, Pieter A. van der Velden, Martine J. Jager, Kaleigh N. Kozak, J. William Harbour
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (5): 1234–1242.
https://doi.org/10.1158/1078-0432.CCR-15-2071
Published: 29 February 2016
View article titled, PRAME as an Independent Biomarker for Metastasis in Uveal Melanoma
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Includes: Supplementary data
Journal Articles

Notch Signaling Promotes Growth and Invasion in Uveal Melanoma

Laura Asnaghi, Katayoon B. Ebrahimi, Karisa C. Schreck, Eli E. Bar, Michael L. Coonfield, W. Robert Bell, James Handa, Shannath L. Merbs, J. William Harbour, Charles G. Eberhart
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (3): 654–665.
https://doi.org/10.1158/1078-0432.CCR-11-1406
Published: 31 January 2012
View article titled, Notch Signaling Promotes Growth and Invasion in Uveal Melanoma
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Includes: Supplementary data
Journal Articles

Histone Deacetylase Inhibitors Induce Growth Arrest and Differentiation in Uveal Melanoma

Solange Landreville, Olga A. Agapova, Katie A. Matatall, Zachary T. Kneass, Michael D. Onken, Ryan S. Lee, Anne M. Bowcock, J. William Harbour
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (2): 408–416.
https://doi.org/10.1158/1078-0432.CCR-11-0946
Published: 16 January 2012
View article titled, Histone Deacetylase Inhibitors Induce Growth Arrest and Differentiation in Uveal Melanoma
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Includes: Supplementary data
Journal Articles

A Metastasis Modifier Locus on Human Chromosome 8p in Uveal Melanoma Identified by Integrative Genomic Analysis

Michael D. Onken, Lori A. Worley, J. William Harbour
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (12): 3737–3745.
https://doi.org/10.1158/1078-0432.CCR-07-5144
Published: 16 June 2008
View article titled, A Metastasis Modifier Locus on Human Chromosome 8p in Uveal Melanoma Identified by Integrative Genomic Analysis
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Journal Articles

Integrative Genomic Analysis of Aneuploidy in Uveal Melanoma

Justis P. Ehlers, Lori Worley, Michael D. Onken, J. William Harbour
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (1): 115–122.
https://doi.org/10.1158/1078-0432.CCR-07-1825
Published: 02 January 2008
View article titled, Integrative Genomic Analysis of Aneuploidy in Uveal Melanoma
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Includes: Supplementary data
Journal Articles

Loss of Heterozygosity of Chromosome 3 Detected with Single Nucleotide Polymorphisms Is Superior to Monosomy 3 for Predicting Metastasis in Uveal Melanoma

Michael D. Onken, Lori A. Worley, Erica Person, Devron H. Char, Anne M. Bowcock, J. William Harbour
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (10): 2923–2927.
https://doi.org/10.1158/1078-0432.CCR-06-2383
Published: 15 May 2007
View article titled, Loss of Heterozygosity of Chromosome 3 Detected with Single Nucleotide Polymorphisms Is Superior to Monosomy 3 for Predicting Metastasis in Uveal Melanoma
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Includes: Supplementary data
Journal Articles

Transcriptomic versus Chromosomal Prognostic Markers and Clinical Outcome in Uveal Melanoma

Lori A. Worley, Michael D. Onken, Erica Person, Diane Robirds, Julie Branson, Devron H. Char, Arie Perry, J. William Harbour
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (5): 1466–1471.
https://doi.org/10.1158/1078-0432.CCR-06-2401
Published: 01 March 2007
View article titled, Transcriptomic versus Chromosomal Prognostic Markers and Clinical Outcome in Uveal Melanoma
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Includes: Supplementary data
Journal Articles

DDEF1 Is Located in an Amplified Region of Chromosome 8q and Is Overexpressed in Uveal Melanoma

Justis P. Ehlers, Lori Worley, Michael D. Onken, J. William Harbour
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (10): 3609–3613.
https://doi.org/10.1158/1078-0432.CCR-04-1941
Published: 16 May 2005
View article titled, <em>DDEF1</em> Is Located in an Amplified Region of Chromosome 8q and Is Overexpressed in Uveal Melanoma
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Journal Articles

NBS1 Expression as a Prognostic Marker in Uveal Melanoma

Justis P. Ehlers, J. William Harbour
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (5): 1849–1853.
https://doi.org/10.1158/1078-0432.CCR-04-2054
Published: 08 March 2005
View article titled, <em>NBS1</em> Expression as a Prognostic Marker in Uveal Melanoma
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