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Irina Ostrovnaya
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Journal Articles

Phase 2 Trial of Regorafenib in Recurrent/Metastatic Adenoid Cystic Carcinoma

Antoine Desilets, Joris L. Vos, Nora Katabi, Fengshen Kuo, Zaineb Nadeem, Maximilian Linxweiler, Irina Ostrovnaya, Shrujal Baxi, Lara A. Dunn, Eric J. Sherman, David G. Pfister, Luc G.T. Morris, Alan L. Ho
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (23): 5281–5292.
https://doi.org/10.1158/1078-0432.CCR-24-1064
Published: 02 December 2024
View article titled, Phase 2 Trial of Regorafenib in Recurrent/Metastatic Adenoid Cystic Carcinoma
Open the PDF for Phase 2 Trial of Regorafenib in Recurrent/Metastatic Adenoid Cystic Carcinoma in another window
Includes: Supplementary data
Journal Articles

Microsatellite Instability, Tumor Mutational Burden, and Response to Immune Checkpoint Blockade in Patients with Prostate Cancer

Andrew T. Lenis, Vignesh Ravichandran, Samantha Brown, Syed M. Alam, Andrew Katims, Hong Truong, Peter A. Reisz, Samantha Vasselman, Barbara Nweji, Karen A. Autio, Michael J. Morris, Susan F. Slovin, Dana Rathkopf, Daniel Danila, Sungmin Woo, Hebert A. Vargas, Vincent P. Laudone, Behfar Ehdaie, Victor Reuter, Maria Arcila, Michael F. Berger, Agnes Viale, Howard I. Scher, Nikolaus Schultz, Anuradha Gopalan, Mark T.A. Donoghue, Irina Ostrovnaya, Konrad H. Stopsack, David B. Solit, Wassim Abida
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (17): 3894–3903.
https://doi.org/10.1158/1078-0432.CCR-23-3403
Published: 03 September 2024
View article titled, Microsatellite Instability, Tumor Mutational Burden, and Response to Immune Checkpoint Blockade in Patients with Prostate Cancer
Open the PDF for Microsatellite Instability, Tumor Mutational Burden, and Response to Immune Checkpoint Blockade in Patients with Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract PO-072: Durvalumab in combination with radioactive iodine in recurrent/metastatic thyroid cancers: Update on clinical and correlative analyses

Antoine Desilets, Winston Wong, Gnana P. Krishnamoorthy, Eric Jeffrey Sherman, Lara Dunn, Anuja Kriplani, James Vincent Fetten, Loren S. Michel, Erin McDonald, Ravinder K. Grewal, Mona Sabra, Laura Boucai, Stephanie Fish, Sofia Haque, Irina Ostrovnaya, Ronald A. Ghossein, James A. Fagin, David G. Pfister, Alan Loh Ho
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (18_Supplement): PO-072.
https://doi.org/10.1158/1557-3265.AACRAHNS23-PO-072
Published: 15 September 2023
View article titled, Abstract PO-072: Durvalumab in combination with radioactive iodine in recurrent/metastatic thyroid cancers: Update on clinical and correlative analyses
Journal Articles

Inherited Germline Cancer Susceptibility Gene Variants in Individuals with Non–Muscle-Invasive Bladder Cancer

Eugene J. Pietzak, Karissa Whiting, Preethi Srinivasan, Chaitanya Bandlamudi, Aliya Khurram, Vijai Joseph, Aleksandra Walasek, Emily Bochner, Timothy Clinton, Nima Almassi, Hong Truong, Manuel R. de Jesus Escano, Michal Wiseman, Diana Mandelker, Yelena Kemel, Liying Zhang, Michael F. Walsh, Karen A. Cadoo, Jonathan A. Coleman, Hikmat Al-Ahmadie, Jonathan E. Rosenberg, Gopakumar V. Iyer, David B. Solit, Irina Ostrovnaya, Kenneth Offit, Mark E. Robson, Zsofia K. Stadler, Michael F. Berger, Dean F. Bajorin, Maria Carlo, Bernard H. Bochner
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (19): 4267–4277.
https://doi.org/10.1158/1078-0432.CCR-22-1006
Published: 03 October 2022
View article titled, Inherited Germline Cancer Susceptibility Gene Variants in Individuals with Non–Muscle-Invasive Bladder Cancer
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Includes: Supplementary data
Journal Articles

A High-Content Screen for C/EBPα Expression Identifies Novel Therapeutic Agents in Dedifferentiated Liposarcoma

Christina V. Angeles, Ana Velez, Jordan Rios, Bernadette Laxa, David Shum, Penelope D. Ruiz, Yawei Shen, Irina Ostrovnaya, Rodrigo Gularte-Mérida, Benjamin A. Nacev, Mark A. Dickson, Hakim Djaballah, Tomoyo Okada, Samuel Singer
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (1): 175–186.
https://doi.org/10.1158/1078-0432.CCR-19-2486
Published: 05 January 2022
View article titled, A High-Content Screen for C/EBPα Expression Identifies Novel Therapeutic Agents in Dedifferentiated Liposarcoma
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Includes: Supplementary data
Journal Articles

Clonal Relatedness and Mutational Differences between Upper Tract and Bladder Urothelial Carcinoma

François Audenet, Sumit Isharwal, Eugene K. Cha, Mark T.A. Donoghue, Esther N. Drill, Irina Ostrovnaya, Eugene J. Pietzak, John P. Sfakianos, Aditya Bagrodia, Paari Murugan, Guido Dalbagni, Timothy F. Donahue, Jonathan E. Rosenberg, Dean F. Bajorin, Maria E. Arcila, Jaclyn F. Hechtman, Michael F. Berger, Barry S. Taylor, Hikmat Al-Ahmadie, Gopa Iyer, Bernard H. Bochner, Jonathan A. Coleman, David B. Solit
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (3): 967–976.
https://doi.org/10.1158/1078-0432.CCR-18-2039
Published: 01 February 2019
View article titled, Clonal Relatedness and Mutational Differences between Upper Tract and Bladder Urothelial Carcinoma
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Includes: Supplementary data
Journal Articles

PTEN Expression, Not Mutation Status in TSC1, TSC2, or mTOR, Correlates with the Outcome on Everolimus in Patients with Renal Cell Carcinoma Treated on the Randomized RECORD-3 Trial

Martin H. Voss, David Chen, Albert Reising, Mahtab Marker, Jiayuan Shi, Jianning Xu, Irina Ostrovnaya, Venkatraman E. Seshan, Almedina Redzematovic, Ying-Bei Chen, Parul Patel, Xia Han, James J. Hsieh, A. Ari Hakimi, Robert J. Motzer
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (2): 506–514.
https://doi.org/10.1158/1078-0432.CCR-18-1833
Published: 15 January 2019
View article titled, PTEN Expression, Not Mutation Status in <em>TSC1, TSC2</em>, or <em>mTOR</em>, Correlates with the Outcome on Everolimus in Patients with Renal Cell Carcinoma Treated on the Randomized RECORD-3 Trial
Open the PDF for PTEN Expression, Not Mutation Status in <em>TSC1, TSC2</em>, or <em>mTOR</em>, Correlates with the Outcome on Everolimus in Patients with Renal Cell Carcinoma Treated on the Randomized RECORD-3 Trial in another window
Includes: Supplementary data
Journal Articles

DNA Damage Response and Repair Gene Alterations Are Associated with Improved Survival in Patients with Platinum-Treated Advanced Urothelial Carcinoma

Min Yuen Teo, Richard M. Bambury, Emily C. Zabor, Emmet Jordan, Hikmat Al-Ahmadie, Mariel E. Boyd, Nancy Bouvier, Stephanie A. Mullane, Eugene K. Cha, Nitin Roper, Irina Ostrovnaya, David M. Hyman, Bernard H. Bochner, Maria E. Arcila, David B. Solit, Michael F. Berger, Dean F. Bajorin, Joaquim Bellmunt, Gopakumar Iyer, Jonathan E. Rosenberg
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (14): 3610–3618.
https://doi.org/10.1158/1078-0432.CCR-16-2520
Published: 13 July 2017
View article titled, DNA Damage Response and Repair Gene Alterations Are Associated with Improved Survival in Patients with Platinum-Treated Advanced Urothelial Carcinoma
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Includes: Supplementary data
Journal Articles

Adverse Outcomes in Clear Cell Renal Cell Carcinoma with Mutations of 3p21 Epigenetic Regulators BAP1 and SETD2: A Report by MSKCC and the KIRC TCGA Research Network

A. Ari Hakimi, Irina Ostrovnaya, Boris Reva, Nikolaus Schultz, Ying-Bei Chen, Mithat Gonen, Han Liu, Shugaku Takeda, Martin H. Voss, Satish K. Tickoo, Victor E. Reuter, Paul Russo, Emily H. Cheng, Chris Sander, Robert J. Motzer, James J. Hsieh
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (12): 3259–3267.
https://doi.org/10.1158/1078-0432.CCR-12-3886
Published: 13 June 2013
View article titled, Adverse Outcomes in Clear Cell Renal Cell Carcinoma with Mutations of 3p21 Epigenetic Regulators <em>BAP1</em> and <em>SETD2</em>: A Report by MSKCC and the KIRC TCGA Research Network
Open the PDF for Adverse Outcomes in Clear Cell Renal Cell Carcinoma with Mutations of 3p21 Epigenetic Regulators <em>BAP1</em> and <em>SETD2</em>: A Report by MSKCC and the KIRC TCGA Research Network in another window
Includes: Supplementary data
Journal Articles

Testing Clonal Relatedness of Tumors Using Array Comparative Genomic Hybridization: A Statistical Challenge

Irina Ostrovnaya, Colin B. Begg
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (5): 1358–1367.
https://doi.org/10.1158/1078-0432.CCR-09-2398
Published: 28 February 2010
View article titled, Testing Clonal Relatedness of Tumors Using Array Comparative Genomic Hybridization: A Statistical Challenge
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Journal Articles

Genomic and Mutational Profiling to Assess Clonal Relationships Between Multiple Non–Small Cell Lung Cancers

Nicolas Girard, Irina Ostrovnaya, Christopher Lau, Bernard Park, Marc Ladanyi, David Finley, Charuhas Deshpande, Valerie Rusch, Irene Orlow, William D. Travis, William Pao, Colin B. Begg
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (16): 5184–5190.
https://doi.org/10.1158/1078-0432.CCR-09-0594
Published: 12 August 2009
View article titled, Genomic and Mutational Profiling to Assess Clonal Relationships Between Multiple Non–Small Cell Lung Cancers
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Includes: Supplementary data