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Journal Articles

Synthetic Lethal Interaction with BCL-XL Blockade Deepens Response to Cetuximab in Patient-Derived Models of Metastatic Colorectal Cancer

Simonetta M. Leto, Martina Ferri, Francesco Sassi, Eugenia R. Zanella, Francesca Cottino, Valentina Vurchio, Irene Catalano, Alessandro Ferrero, Caterina C. Zingaretti, Caterina Marchiò, Elena Grassi, Livio Trusolino, Andrea Bertotti
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (6): 1102–1113.
https://doi.org/10.1158/1078-0432.CCR-22-2550
Published: 14 March 2023
View article titled, Synthetic Lethal Interaction with BCL-XL Blockade Deepens Response to Cetuximab in Patient-Derived Models of Metastatic Colorectal Cancer
Open the PDF for Synthetic Lethal Interaction with BCL-XL Blockade Deepens Response to Cetuximab in Patient-Derived Models of Metastatic Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Sustained Inhibition of HER3 and EGFR Is Necessary to Induce Regression of HER2-Amplified Gastrointestinal Carcinomas

Simonetta M. Leto, Francesco Sassi, Irene Catalano, Valter Torri, Giorgia Migliardi, Eugenia R. Zanella, Mark Throsby, Andrea Bertotti, Livio Trusolino
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2015) 21 (24): 5519–5531.
https://doi.org/10.1158/1078-0432.CCR-14-3066
Published: 14 December 2015
View article titled, Sustained Inhibition of HER3 and EGFR Is Necessary to Induce Regression of <em>HER2</em>-Amplified Gastrointestinal Carcinomas
Open the PDF for Sustained Inhibition of HER3 and EGFR Is Necessary to Induce Regression of <em>HER2</em>-Amplified Gastrointestinal Carcinomas in another window
Includes: Supplementary data
Journal Articles

Abstract B43: HER2-amplified gastric and colorectal cancers: Mechanistic insights into HER2 targeting approaches

Simonetta Maria Leto, Francesco Sassi, Giorgia Migliardi, Eugenia Zanella, Irene Catalano, Andrea Bertotti, Livio Trusolino
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (4_Supplement): B43.
https://doi.org/10.1158/1557-3265.PMS14-B43
Published: 13 February 2015
View article titled, Abstract B43: HER2-amplified gastric and colorectal cancers: Mechanistic insights into HER2 targeting approaches