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Igor Astsaturov
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Journal Articles

Phase Ib Study of Wnt Inhibitor Ipafricept with Gemcitabine and nab-paclitaxel in Patients with Previously Untreated Stage IV Pancreatic Cancer

Efrat Dotan, Dana B. Cardin, Heinz-Josef Lenz, Wells Messersmith, Bert O'Neil, Steven J. Cohen, Crystal S. Denlinger, Safi Shahda, Igor Astsaturov, Ann M. Kapoun, Rainer K. Brachmann, Shailaja Uttamsingh, Robert J. Stagg, Colin Weekes
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (20): 5348–5357.
https://doi.org/10.1158/1078-0432.CCR-20-0489
Published: 15 October 2020
View article titled, Phase Ib Study of Wnt Inhibitor Ipafricept with Gemcitabine and nab-paclitaxel in Patients with Previously Untreated Stage IV Pancreatic Cancer
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Journal Articles

Abstract PR01: Assessment of PARPi and cisplatin resistance in BRCA1 exon 11 mutant patient -derived xenografts

John J Krais, Emma Clausen, Vladimir Khazak, Igor Astsaturov, Clare L Scott, Neil Johnson
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (13_Supplement): PR01.
https://doi.org/10.1158/1557-3265.OVCA19-PR01
Published: 01 July 2020
View article titled, Abstract PR01: Assessment of PARPi and cisplatin resistance in <em>BRCA1</em> exon 11 mutant patient -derived xenografts
Journal Articles

Statins Synergize with Hedgehog Pathway Inhibitors for Treatment of Medulloblastoma

Renata E. Gordon, Li Zhang, Suraj Peri, Yin-Ming Kuo, Fang Du, Brian L. Egleston, Jessica M. Y. Ng, Andrew J. Andrews, Igor Astsaturov, Tom Curran, Zeng-Jie Yang
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (6): 1375–1388.
https://doi.org/10.1158/1078-0432.CCR-17-2923
Published: 14 March 2018
View article titled, Statins Synergize with Hedgehog Pathway Inhibitors for Treatment of Medulloblastoma
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Includes: Supplementary data
Journal Articles

Screening of Conditionally Reprogrammed Patient-Derived Carcinoma Cells Identifies ERCC3–MYC Interactions as a Target in Pancreatic Cancer

Natalya Beglyarova, Eugenia Banina, Yan Zhou, Ramilia Mukhamadeeva, Grigorii Andrianov, Egor Bobrov, Elena Lysenko, Natalya Skobeleva, Linara Gabitova, Diana Restifo, Max Pressman, Ilya G. Serebriiskii, John P. Hoffman, Keren Paz, Diana Behrens, Vladimir Khazak, Sandra A. Jablonski, Erica A. Golemis, Louis M. Weiner, Igor Astsaturov
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (24): 6153–6163.
https://doi.org/10.1158/1078-0432.CCR-16-0149
Published: 15 December 2016
View article titled, Screening of Conditionally Reprogrammed Patient-Derived Carcinoma Cells Identifies ERCC3–MYC Interactions as a Target in Pancreatic Cancer
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Includes: Supplementary data
Journal Articles

Abstract B07: Screening of patient-derived carcinoma cells and animal models identifies transcription as target in pancreatic cancer.

Vladimir Khazak, Natalia Skobeleva, Natalia Beglyarova, Egor Bobrov, Yan Zhou, Sandra A. Jablonski, Louis M. Weiner, Keren Paz, Igor Astsaturov
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16_Supplement): B07.
https://doi.org/10.1158/1557-3265.PDX16-B07
Published: 15 August 2016
View article titled, Abstract B07: Screening of patient-derived carcinoma cells and animal models identifies transcription as target in pancreatic cancer.
Journal Articles

Molecular Pathways: Sterols and Receptor Signaling in Cancer

Linara Gabitova, Andrey Gorin, Igor Astsaturov
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (1): 28–34.
https://doi.org/10.1158/1078-0432.CCR-13-0122
Published: 05 January 2014
View article titled, Molecular Pathways: Sterols and Receptor Signaling in Cancer
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Journal Articles

Network Analysis Identifies an HSP90-Central Hub Susceptible in Ovarian Cancer

Hanqing Liu, Fang Xiao, Ilya G. Serebriiskii, Shane W. O'Brien, Marisa A. Maglaty, Igor Astsaturov, Samuel Litwin, Lainie P. Martin, David A. Proia, Erica A. Golemis, Denise C. Connolly
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (18): 5053–5067.
https://doi.org/10.1158/1078-0432.CCR-13-1115
Published: 16 September 2013
View article titled, Network Analysis Identifies an HSP90-Central Hub Susceptible in Ovarian Cancer
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Includes: Supplementary data
Journal Articles

Amplification of Virus-Induced Antimelanoma T-Cell Reactivity by High-Dose Interferon-α2b: Implications for Cancer Vaccines

Igor Astsaturov, Teresa Petrella, E. Umit Bagriacik, Mark de Benedette, Robert Uger, Gail Lumber, Neil Berinstein, Ileana Elias, Neill Iscoe, Caitlin Hammond, Paul Hamilton, David E. Spaner
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (12): 4347–4355.
Published: 10 October 2003
View article titled, Amplification of Virus-Induced Antimelanoma T-Cell Reactivity by High-Dose Interferon-α2b: <subtitle>Implications for Cancer Vaccines</subtitle>
Open the PDF for Amplification of Virus-Induced Antimelanoma T-Cell Reactivity by High-Dose Interferon-α2b: <subtitle>Implications for Cancer Vaccines</subtitle> in another window