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Ie-Ming Shih
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Journal Articles

Abstract B002: ARID1A loss activates MAPK signaling via DUSP4 downregulation: a mechanistic insight in endometrial carcinoma

Jayaprakash Mandal, Zheng-Cheng Yu, Ie-Ming Shih, Tian-Li Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (5_Supplement): B002.
https://doi.org/10.1158/1557-3265.ENDO24-B002
Published: 01 March 2024
View article titled, Abstract B002: ARID1A loss activates MAPK signaling via DUSP4 downregulation: a mechanistic insight in endometrial carcinoma
Journal Articles

Aneuploidy Landscape in Precursors of Ovarian Cancer

Yeh Wang, Christopher Douville, Yen-Wei Chien, Brant G. Wang, Chi-Long Chen, Andre Pinto, Saron Ann Smith, Ronny Drapkin, M. Herman Chui, Tricia Numan, Russell Vang, Nickolas Papadopoulos, Tian-Li Wang, Ie-Ming Shih
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (3): 600–615.
https://doi.org/10.1158/1078-0432.CCR-23-0932
Published: 01 February 2024
View article titled, Aneuploidy Landscape in Precursors of Ovarian Cancer
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Includes: Supplementary data
Journal Articles

C ombination A TR (ceralasertib) and P A R P (olaparib) I nhibitor (CAPRI) Trial in Acquired PARP Inhibitor–Resistant Homologous Recombination–Deficient Ovarian Cancer

Stephanie L. Wethington, Payal D. Shah, Lainie Martin, Janos L. Tanyi, Nawar Latif, Mark Morgan, Drew A. Torigian, Diego Rodriguez, Simon A. Smith, Emma Dean, Susan M. Domchek, Ronny Drapkin, Ie-Ming Shih, Eric J. Brown, Wei-Ting Hwang, Deborah K. Armstrong, Stephanie Gaillard, Robert Giuntoli, Fiona Simpkins
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (15): 2800–2807.
https://doi.org/10.1158/1078-0432.CCR-22-2444
Published: 01 August 2023
View article titled, C ombination A TR (ceralasertib) and P A R P (olaparib) I nhibitor (CAPRI) Trial in Acquired PARP Inhibitor–Resistant Homologous Recombination–Deficient Ovarian Cancer
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Includes: Supplementary data
Journal Articles

Methylomic Landscapes of Ovarian Cancer Precursor Lesions

Thomas R. Pisanic, II, Yeh Wang, Hanru Sun, Michael Considine, Lihong Li, Tza-Huei Wang, Tian-Li Wang, Ie-Ming Shih
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (23): 6310–6320.
https://doi.org/10.1158/1078-0432.CCR-20-0270
Published: 01 December 2020
View article titled, Methylomic Landscapes of Ovarian Cancer Precursor Lesions
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Includes: Supplementary data
Journal Articles

Abstract B21: Oncogenic BRAF and KRAS mutations in endosalpingiosis

M. Herman Chui, Ie-Ming Shih
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (13_Supplement): B21.
https://doi.org/10.1158/1557-3265.OVCA19-B21
Published: 01 July 2020
View article titled, Abstract B21: Oncogenic BRAF and KRAS mutations in endosalpingiosis
Journal Articles

Loss of ARID1A in Tumor Cells Renders Selective Vulnerability to Combined Ionizing Radiation and PARP Inhibitor Therapy

Youngran Park, M. Herman Chui, Yohan Suryo Rahmanto, Zheng-Cheng Yu, Raghavendra A. Shamanna, Marina A. Bellani, Stephanie Gaillard, Ayse Ayhan, Akila Viswanathan, Michael M. Seidman, Sonia Franco, Anthony K.L. Leung, Vilhelm A. Bohr, Ie-Ming Shih, Tian-Li Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (18): 5584–5594.
https://doi.org/10.1158/1078-0432.CCR-18-4222
Published: 13 September 2019
View article titled, Loss of ARID1A in Tumor Cells Renders Selective Vulnerability to Combined Ionizing Radiation and PARP Inhibitor Therapy
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Includes: Supplementary data
Journal Articles

Methylomic Analysis of Ovarian Cancers Identifies Tumor-Specific Alterations Readily Detectable in Early Precursor Lesions

Thomas R. Pisanic, II, Leslie M. Cope, Shiou-Fu Lin, Ting-Tai Yen, Pornpat Athamanolap, Ryoichi Asaka, Kentaro Nakayama, Amanda N. Fader, Tza-Huei Wang, Ie-Ming Shih, Tian-Li Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (24): 6536–6547.
https://doi.org/10.1158/1078-0432.CCR-18-1199
Published: 13 December 2018
View article titled, Methylomic Analysis of Ovarian Cancers Identifies Tumor-Specific Alterations Readily Detectable in Early Precursor Lesions
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Includes: Supplementary data
Journal Articles

Abstract IA16: PapGene, PapSEEK, and PapDREAming for early detection of ovarian cancer

Ie-Ming Shih
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (15_Supplement): IA16.
https://doi.org/10.1158/1557-3265.OVCA17-IA16
Published: 01 August 2018
View article titled, Abstract IA16: PapGene, PapSEEK, and PapDREAming for early detection of ovarian cancer
Journal Articles

Abstract A80: NAC1 attenuates BCL6 negative autoregulation and functions as a BCL6 coactivator of FOXQ1 transcription in ovarian cancer (OVCA).

Alice Laschuk Herlinger, Min Gao, Ren-Chin Wu, Tian-Li Wang, Leticia B A Rangel, Ie-Ming Shih
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (2_Supplement): A80.
https://doi.org/10.1158/1557-3265.OVCA15-A80
Published: 15 January 2016
View article titled, Abstract A80: NAC1 attenuates BCL6 negative autoregulation and functions as a BCL6 coactivator of FOXQ1 transcription in ovarian cancer (OVCA).
Journal Articles

Abstract A32: PBX1, a transcriptional regulator, promotes stemness and chemoresistance in ovarian cancer.

Jin-Gyoung Jung, Tae-Hoen Kim, Emily Gerry, Jen-Chun Kuan, Ayse Ayhan, Ben Davidson, Ie-Ming Shih, Tian-Li Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (2_Supplement): A32.
https://doi.org/10.1158/1557-3265.OVCA15-A32
Published: 15 January 2016
View article titled, Abstract A32: PBX1, a transcriptional regulator, promotes stemness and chemoresistance in ovarian cancer.
Journal Articles

Abstract B16: Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated ovarian cancers.

Benjamin Bitler, Ie-Ming Shih, Rugang Zhang
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (2_Supplement): B16.
https://doi.org/10.1158/1557-3265.OVCA15-B16
Published: 15 January 2016
View article titled, Abstract B16: Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated ovarian cancers.
Journal Articles

Abstract IA16: Endometriosis-related ovarian cancer.

Ie-Ming Shih
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (2_Supplement): IA16.
https://doi.org/10.1158/1557-3265.OVCA15-IA16
Published: 15 January 2016
View article titled, Abstract IA16: Endometriosis-related ovarian cancer.
Journal Articles

Mevalonate Pathway Antagonist Suppresses Formation of Serous Tubal Intraepithelial Carcinoma and Ovarian Carcinoma in Mouse Models

Yusuke Kobayashi, Hiroyasu Kashima, Ren-Chin Wu, Jin-Gyoung Jung, Jen-Chun Kuan, Jinghua Gu, Jianhua Xuan, Lori Sokoll, Kala Visvanathan, Ie-Ming Shih, Tian-Li Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (20): 4652–4662.
https://doi.org/10.1158/1078-0432.CCR-14-3368
Published: 14 October 2015
View article titled, Mevalonate Pathway Antagonist Suppresses Formation of Serous Tubal Intraepithelial Carcinoma and Ovarian Carcinoma in Mouse Models
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Includes: Supplementary data
Journal Articles

Abstract B15: Targeting PBX1 signaling to sensitize carboplatin cytotoxicity in ovarian cancer

Jin G. Jung, Joon T. Park, Alexader Stoeck, Tasmeen Hussain, Ren-Chin Wu, Ie-Ming Shih, Tian-Li Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (4_Supplement): B15.
https://doi.org/10.1158/1557-3265.PMS14-B15
Published: 13 February 2015
View article titled, Abstract B15: Targeting PBX1 signaling to sensitize carboplatin cytotoxicity in ovarian cancer
Journal Articles

A novel quantum dot based nanoassay for high resolution copy number variation detection and DNA methylation quantification

Yi Zhang, Ie-Ming Shih, Tian-Li Wang, Tza-Huei Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (19_Supplement): A17.
https://doi.org/10.1158/DIAG-10-A17
Published: 15 August 2014
View article titled, A novel quantum dot based nanoassay for high resolution copy number variation detection and DNA methylation quantification
Journal Articles

DNA Copy Numbers Profiles in Affinity-Purified Ovarian Clear Cell Carcinoma

Kuan-Ting Kuo, Tsui-Lien Mao, Xu Chen, Yuanjian Feng, Kentaro Nakayama, Yue Wang, Ruth Glas, M. Joe Ma, Robert J. Kurman, Ie-Ming Shih, Tian-Li Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (7): 1997–2008.
https://doi.org/10.1158/1078-0432.CCR-09-2105
Published: 31 March 2010
View article titled, DNA Copy Numbers Profiles in Affinity-Purified Ovarian Clear Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Annexin XI Is Associated with Cisplatin Resistance and Related to Tumor Recurrence in Ovarian Cancer Patients

Jin Song, Ie-ming Shih, Ritu Salani, Daniel W. Chan, Zhen Zhang
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (22): 6842–6849.
https://doi.org/10.1158/1078-0432.CCR-07-0569
Published: 15 November 2007
View article titled, Annexin XI Is Associated with Cisplatin Resistance and Related to Tumor Recurrence in Ovarian Cancer Patients
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Journal Articles

Measurement of Cyclin E Genomic Copy Number and Strand Length in Cell-Free DNA Distinguish Malignant versus Benign Effusions

Ritu Salani, Ben Davidson, Michael Fiegl, Christian Marth, Elisabeth Müller-Holzner, Guenther Gastl, Han-Yao Huang, Jui-Chi Hsiao, Her-Sheng Lin, Tian-Li Wang, Bai-Ling Lin, Ie-Ming Shih
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (19): 5805–5809.
https://doi.org/10.1158/1078-0432.CCR-07-0853
Published: 01 October 2007
View article titled, Measurement of Cyclin E Genomic Copy Number and Strand Length in Cell-Free DNA Distinguish Malignant versus Benign Effusions
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Journal Articles

Gene Expression Signatures Differentiate Ovarian/Peritoneal Serous Carcinoma from Diffuse Malignant Peritoneal Mesothelioma

Ben Davidson, Zhen Zhang, Lilach Kleinberg, Mei Li, Vivi Ann Flørenes, Tian-Li Wang, Ie-Ming Shih
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (20): 5944–5950.
https://doi.org/10.1158/1078-0432.CCR-06-1059
Published: 24 October 2006
View article titled, Gene Expression Signatures Differentiate Ovarian/Peritoneal Serous Carcinoma from Diffuse Malignant Peritoneal Mesothelioma
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Includes: Supplementary data
Journal Articles

Diffuse Mesothelin Expression Correlates with Prolonged Patient Survival in Ovarian Serous Carcinoma

M. Jim Yen, Chih-Yi Hsu, Tsui-Lien Mao, T-C. Wu, Richard Roden, Tian-Li Wang, Ie-Ming Shih
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (3): 827–831.
https://doi.org/10.1158/1078-0432.CCR-05-1397
Published: 07 February 2006
View article titled, Diffuse Mesothelin Expression Correlates with Prolonged Patient Survival in Ovarian Serous Carcinoma
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