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Ian F. Tannock
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Journal Articles

Failures in Phase III: Causes and Consequences

Bostjan Seruga, Alberto Ocana, Eitan Amir, Ian F. Tannock
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (20): 4552–4560.
https://doi.org/10.1158/1078-0432.CCR-15-0124
Published: 14 October 2015
View article titled, Failures in Phase III: Causes and Consequences
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Includes: Supplementary data
Journal Articles

Chemotherapy Rescues Hypoxic Tumor Cells and Induces Their Reoxygenation and Repopulation—An Effect That Is Inhibited by the Hypoxia-Activated Prodrug TH-302

Jasdeep K. Saggar, Ian F. Tannock
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (9): 2107–2114.
https://doi.org/10.1158/1078-0432.CCR-14-2298
Published: 30 April 2015
View article titled, Chemotherapy Rescues Hypoxic Tumor Cells and Induces Their Reoxygenation and Repopulation—An Effect That Is Inhibited by the Hypoxia-Activated Prodrug TH-302
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Includes: Supplementary data
Journal Articles

Use of the Proton Pump Inhibitor Pantoprazole to Modify the Distribution and Activity of Doxorubicin: A Potential Strategy to Improve the Therapy of Solid Tumors

Krupa J. Patel, Carol Lee, Qian Tan, Ian F. Tannock
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (24): 6766–6776.
https://doi.org/10.1158/1078-0432.CCR-13-0128
Published: 16 December 2013
View article titled, Use of the Proton Pump Inhibitor Pantoprazole to Modify the Distribution and Activity of Doxorubicin: A Potential Strategy to Improve the Therapy of Solid Tumors
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Journal Articles

Phase III Trials of Targeted Anticancer Therapies: Redesigning the Concept

Alberto Ocana, Eitan Amir, Francisco Vera-Badillo, Bostjan Seruga, Ian F. Tannock
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (18): 4931–4940.
https://doi.org/10.1158/1078-0432.CCR-13-1222
Published: 16 September 2013
View article titled, Phase III Trials of Targeted Anticancer Therapies: Redesigning the Concept
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Journal Articles

The Effects of Chemotherapy on Cognitive Function in a Mouse Model: A Prospective Study

Gordon Winocur, Mark Henkelman, J. Martin Wojtowicz, Haibo Zhang, Malcolm A. Binns, Ian F. Tannock
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (11): 3112–3121.
https://doi.org/10.1158/1078-0432.CCR-12-0060
Published: 31 May 2012
View article titled, The Effects of Chemotherapy on Cognitive Function in a Mouse Model: A Prospective Study
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Includes: Supplementary data
Journal Articles

Concurrent and Sequential Administration of Chemotherapy and the Mammalian Target of Rapamycin Inhibitor Temsirolimus in Human Cancer Cells and Xenografts

Andrea S. Fung, Licun Wu, Ian F. Tannock
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (17): 5389–5395.
https://doi.org/10.1158/1078-0432.CCR-08-3007
Published: 31 August 2009
View article titled, Concurrent and Sequential Administration of Chemotherapy and the Mammalian Target of Rapamycin Inhibitor Temsirolimus in Human Cancer Cells and Xenografts
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Journal Articles

Treatment of Hormone-Refractory Prostate Cancer with Docetaxel or Mitoxantrone: Relationships between Prostate-Specific Antigen, Pain, and Quality of Life Response and Survival in the TAX-327 Study

Dominik R. Berthold, Gregory R. Pond, Martin Roessner, Ronald de Wit, Mario Eisenberger, and Ian F. Tannock, on behalf of the TAX-327 investigators
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (9): 2763–2767.
https://doi.org/10.1158/1078-0432.CCR-07-0944
Published: 01 May 2008
View article titled, Treatment of Hormone-Refractory Prostate Cancer with Docetaxel or Mitoxantrone: Relationships between Prostate-Specific Antigen, Pain, and Quality of Life Response and Survival in the TAX-327 Study
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Journal Articles

A Contemporary Prognostic Nomogram for Men with Hormone-Refractory Metastatic Prostate Cancer: A TAX327 Study Analysis

Andrew J. Armstrong, Elizabeth S. Garrett-Mayer, Yi-Chun Ou Yang, Ronald de Wit, Ian F. Tannock, Mario Eisenberger
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (21): 6396–6403.
https://doi.org/10.1158/1078-0432.CCR-07-1036
Published: 01 November 2007
View article titled, A Contemporary Prognostic Nomogram for Men with Hormone-Refractory Metastatic Prostate Cancer: A TAX327 Study Analysis
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Includes: Supplementary data
Journal Articles

The Distribution of the Anticancer Drug Doxorubicin in Relation to Blood Vessels in Solid Tumors

Andrew J. Primeau, Augusto Rendon, David Hedley, Lothar Lilge, Ian F. Tannock
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (24): 8782–8788.
https://doi.org/10.1158/1078-0432.CCR-05-1664
Published: 16 December 2005
View article titled, The Distribution of the Anticancer Drug Doxorubicin in Relation to Blood Vessels in Solid Tumors
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Journal Articles

Effect of the Selective Estrogen Receptor Modulator Arzoxifene on Repopulation of Hormone-Responsive Breast Cancer Xenografts between Courses of Chemotherapy

Licun Wu, Ian F. Tannock
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (22): 8195–8200.
https://doi.org/10.1158/1078-0432.CCR-05-1258
Published: 18 November 2005
View article titled, Effect of the Selective Estrogen Receptor Modulator Arzoxifene on Repopulation of Hormone-Responsive Breast Cancer Xenografts between Courses of Chemotherapy
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Journal Articles

Reduction of Intracellular pH as a Strategy to Enhance the pH-Dependent Cytotoxic Effects of Melphalan for Human Breast Cancer Cells

Philip Wong, Carol Lee, Ian F. Tannock
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (9): 3553–3557.
https://doi.org/10.1158/1078-0432.CCR-04-2472
Published: 02 May 2005
View article titled, Reduction of Intracellular pH as a Strategy to Enhance the pH-Dependent Cytotoxic Effects of Melphalan for Human Breast Cancer Cells
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Journal Articles

Selective Estrogen Receptor Modulators as Inhibitors of Repopulation of Human Breast Cancer Cell Lines after Chemotherapy

Wu Licun, Ian F. Tannock
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (12): 4614–4618.
Published: 10 October 2003
View article titled, Selective Estrogen Receptor Modulators as Inhibitors of Repopulation of Human Breast Cancer Cell Lines after Chemotherapy
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Journal Articles

Limited Penetration of Anticancer Drugs through Tumor Tissue: A Potential Cause of Resistance of Solid Tumors to Chemotherapy

Ian F. Tannock, Carol M. Lee, Jonathon K. Tunggal, David S. M. Cowan, Merrill J. Egorin
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (3): 878–884.
Published: 01 March 2002
View article titled, Limited Penetration of Anticancer Drugs through Tumor Tissue: <subtitle>A Potential Cause of Resistance of Solid Tumors to Chemotherapy</subtitle>
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Journal Articles

Penetration of Anticancer Drugs through Solid Tissue: A Factor That Limits the Effectiveness of Chemotherapy for Solid Tumors

Jonathan K. Tunggal, David S. M. Cowan, Hafsa Shaikh, Ian F. Tannock
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (6): 1583–1586.
Published: 01 June 1999
View article titled, Penetration of Anticancer Drugs through Solid Tissue: A Factor That Limits the Effectiveness of Chemotherapy for Solid Tumors
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