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Ian E. Krop
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Journal Articles

Genomic Characterization of de novo Metastatic Breast Cancer

Ana C. Garrido-Castro, Liam F. Spurr, Melissa E. Hughes, Yvonne Y. Li, Andrew D. Cherniack, Priti Kumari, Maxwell R. Lloyd, Brittany Bychkovsky, Romualdo Barroso-Sousa, Simona Di Lascio, Esha Jain, Janet Files, Ayesha Mohammed-Abreu, Max Krevalin, Colin MacKichan, William T. Barry, Hao Guo, Daniel Xia, Ethan Cerami, Barrett J. Rollins, Laura E. MacConaill, Neal I. Lindeman, Ian E. Krop, Bruce E. Johnson, Nikhil Wagle, Eric P. Winer, Deborah A. Dillon, Nancy U. Lin
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (4): 1105–1118.
DOI: https://doi.org/10.1158/1078-0432.CCR-20-1720
Published: 15 February 2021
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Changes in Peripheral and Local Tumor Immunity after Neoadjuvant Chemotherapy Reshape Clinical Outcomes in Patients with Breast Cancer

Margaret L. Axelrod, Mellissa J. Nixon, Paula I. Gonzalez-Ericsson, Riley E. Bergman, Mark A. Pilkinton, Wyatt J. McDonnell, Violeta Sanchez, Susan R. Opalenik, Sherene Loi, Jing Zhou, Sean Mackay, Brent N. Rexer, Vandana G. Abramson, Valerie M. Jansen, Simon Mallal, Joshua Donaldson, Sara M. Tolaney, Ian E. Krop, Ana C. Garrido-Castro, Jonathan D. Marotti, Kevin Shee, Todd W. Miller, Melinda E. Sanders, Ingrid A. Mayer, Roberto Salgado, Justin M. Balko
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (21): 5668–5681.
DOI: https://doi.org/10.1158/1078-0432.CCR-19-3685
Published: 02 November 2020
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Tumor Mutational Burden and PTEN Alterations as Molecular Correlates of Response to PD-1/L1 Blockade in Metastatic Triple-Negative Breast Cancer

Romualdo Barroso-Sousa, Tanya E. Keenan, Sonia Pernas, Pedro Exman, Esha Jain, Ana C. Garrido-Castro, Melissa Hughes, Brittany Bychkovsky, Renato Umeton, Janet L. Files, Neal I. Lindeman, Laura E. MacConaill, F. Stephen Hodi, Ian E. Krop, Deborah Dillon, Eric P. Winer, Nikhil Wagle, Nancy U. Lin, Elizabeth A. Mittendorf, Eliezer M. Van Allen, Sara M. Tolaney
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (11): 2565–2572.
DOI: https://doi.org/10.1158/1078-0432.CCR-19-3507
Published: 01 June 2020
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The Immune Microenvironment in Hormone Receptor–Positive Breast Cancer Before and After Preoperative Chemotherapy

Adrienne G. Waks, Daniel G. Stover, Jennifer L. Guerriero, Deborah Dillon, William T. Barry, Evisa Gjini, Christina Hartl, Wesley Lo, Jennifer Savoie, Jane Brock, Robert Wesolowski, Zaibo Li, Adrienne Damicis, Anne V. Philips, Yun Wu, Fei Yang, Amy Sullivan, Patrick Danaher, Heather Ann Brauer, Wafa Osmani, Mikel Lipschitz, Katherine A. Hoadley, Michael Goldberg, Charles M. Perou, Scott Rodig, Eric P. Winer, Ian E. Krop, Elizabeth A. Mittendorf, Sara M. Tolaney
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (15): 4644–4655.
DOI: https://doi.org/10.1158/1078-0432.CCR-19-0173
Published: 01 August 2019
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Integrated Analysis of RNA and DNA from the Phase III Trial CALGB 40601 Identifies Predictors of Response to Trastuzumab-Based Neoadjuvant Chemotherapy in HER2-Positive Breast Cancer

Maki Tanioka, Cheng Fan, Joel S. Parker, Katherine A. Hoadley, Zhiyuan Hu, Yan Li, Terry M. Hyslop, Brandelyn N. Pitcher, Matthew G. Soloway, Patricia A. Spears, Lynn N. Henry, Sara Tolaney, Chau T. Dang, Ian E. Krop, Lyndsay N. Harris, Donald A. Berry, Elaine R. Mardis, Eric P. Winer, Clifford A. Hudis, Lisa A. Carey, Charles M. Perou
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (21): 5292–5304.
DOI: https://doi.org/10.1158/1078-0432.CCR-17-3431
Published: 01 November 2018
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Phase II Study of Taselisib (GDC-0032) in Combination with Fulvestrant in Patients with HER2-Negative, Hormone Receptor–Positive Advanced Breast Cancer

Maura N. Dickler, Cristina Saura, Donald A. Richards, Ian E. Krop, Andrés Cervantes, Philippe L. Bedard, Manish R. Patel, Lajos Pusztai, Mafalda Oliveira, Alison K. Cardenas, Na Cui, Timothy R. Wilson, Thomas J. Stout, Michael C. Wei, Jerry Y. Hsu, José Baselga
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (18): 4380–4387.
DOI: https://doi.org/10.1158/1078-0432.CCR-18-0613
Published: 14 September 2018
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Immune Signatures Following Single Dose Trastuzumab Predict Pathologic Response to PreoperativeTrastuzumab and Chemotherapy in HER2-Positive Early Breast Cancer

Vinay Varadan, Hannah Gilmore, Kristy L.S. Miskimen, David Tuck, Shikha Parsai, Amad Awadallah, Ian E. Krop, Eric P. Winer, Veerle Bossuyt, George Somlo, Maysa M. Abu-Khalaf, Mary Anne Fenton, William Sikov, Lyndsay N. Harris
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (13): 3249–3259.
DOI: https://doi.org/10.1158/1078-0432.CCR-15-2021
Published: 30 June 2016
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PlGF/VEGFR-1 Signaling Promotes Macrophage Polarization and Accelerated Tumor Progression in Obesity

Joao Incio, Josh Tam, Nuh N. Rahbari, Priya Suboj, Dan T. McManus, Shan M. Chin, Trupti D. Vardam, Ana Batista, Suboj Babykutty, Keehoon Jung, Anna Khachatryan, Tai Hato, Jennifer A. Ligibel, Ian E. Krop, Stefan B. Puchner, Christopher L. Schlett, Udo Hoffmman, Marek Ancukiewicz, Masabumi Shibuya, Peter Carmeliet, Raquel Soares, Dan G. Duda, Rakesh K. Jain, Dai Fukumura
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2016) 22 (12): 2993–3004.
DOI: https://doi.org/10.1158/1078-0432.CCR-15-1839
Published: 14 June 2016
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Ribavirin Treatment Effects on Breast Cancers Overexpressing eIF4E, a Biomarker with Prognostic Specificity for Luminal B-Type Breast Cancer

Filippa Pettersson, Christina Yau, Monica C. Dobocan, Biljana Culjkovic-Kraljacic, Hélène Retrouvay, Rachel Puckett, Ludmila M. Flores, Ian E. Krop, Caroline Rousseau, Eftihia Cocolakis, Katherine L. B. Borden, Christopher C. Benz, Wilson H. Miller, Jr.
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (9): 2874–2884.
DOI: https://doi.org/10.1158/1078-0432.CCR-10-2334
Published: 01 May 2011
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Advances in Targeting Src in the Treatment of Breast Cancer and Other Solid Malignancies

Erica L. Mayer, Ian E. Krop
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (14): 3526–3532.
DOI: https://doi.org/10.1158/1078-0432.CCR-09-1834
Published: 14 July 2010
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Journal Articles

Epithelial and Stromal Cathepsin K and CXCL14 Expression in Breast Tumor Progression

Celina G. Kleer, Noga Bloushtain-Qimron, Yu-Hui Chen, Daniel Carrasco, Min Hu, Jun Yao, Stine-Kathrein Kraeft, Laura C. Collins, Michael S. Sabel, Pedram Argani, Rebecca Gelman, Stuart J. Schnitt, Ian E. Krop, Kornelia Polyak
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (17): 5357–5367.
DOI: https://doi.org/10.1158/1078-0432.CCR-08-0732
Published: 02 September 2008
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