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Huw D. Thomas
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Journal Articles

DNA-PK—A Candidate Driver of Hepatocarcinogenesis and Tissue Biomarker That Predicts Response to Treatment and Survival

Liam Cornell, Joanne M. Munck, Clara Alsinet, Augusto Villanueva, Laura Ogle, Catherine E. Willoughby, Despina Televantou, Huw D. Thomas, Jennifer Jackson, Alastair D. Burt, David Newell, John Rose, Derek M. Manas, Geoffrey I. Shapiro, Nicola J. Curtin, Helen L. Reeves
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (4): 925–933.
https://doi.org/10.1158/1078-0432.CCR-14-0842
Published: 16 February 2015
View article titled, DNA-PK—A Candidate Driver of Hepatocarcinogenesis and Tissue Biomarker That Predicts Response to Treatment and Survival
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Includes: Supplementary data
Journal Articles

Vasoactivity of AG014699, a Clinically Active Small Molecule Inhibitor of Poly(ADP-ribose) Polymerase: a Contributory Factor to Chemopotentiation In vivo?

Majid Ali, Brian A. Telfer, Cian McCrudden, Martin O'Rourke, Huw D. Thomas, Marzieh Kamjoo, Suzanne Kyle, Tracy Robson, Chris Shaw, David G. Hirst, Nicola J. Curtin, Kaye J. Williams
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (19): 6106–6112.
https://doi.org/10.1158/1078-0432.CCR-09-0398
Published: 30 September 2009
View article titled, Vasoactivity of AG014699, a Clinically Active Small Molecule Inhibitor of Poly(ADP-ribose) Polymerase: a Contributory Factor to Chemopotentiation <em>In vivo</em>?
Open the PDF for Vasoactivity of AG014699, a Clinically Active Small Molecule Inhibitor of Poly(ADP-ribose) Polymerase: a Contributory Factor to Chemopotentiation <em>In vivo</em>? in another window
Includes: Supplementary data
Journal Articles

Inhibition of Poly(ADP-Ribose) Polymerase-1 Enhances Temozolomide and Topotecan Activity against Childhood Neuroblastoma

Rachel A. Daniel, Agata L. Rozanska, Huw D. Thomas, Evan A. Mulligan, Yvette Drew, Deborah J. Castelbuono, Zdenek Hostomsky, E. Ruth Plummer, Alan V. Boddy, Deborah A. Tweddle, Nicola J. Curtin, Steven C. Clifford
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (4): 1241–1249.
https://doi.org/10.1158/1078-0432.CCR-08-1095
Published: 19 February 2009
View article titled, Inhibition of Poly(ADP-Ribose) Polymerase-1 Enhances Temozolomide and Topotecan Activity against Childhood Neuroblastoma
Open the PDF for Inhibition of Poly(ADP-Ribose) Polymerase-1 Enhances Temozolomide and Topotecan Activity against Childhood Neuroblastoma in another window
Includes: Supplementary data
Journal Articles

Identification of Potent Nontoxic Poly(ADP-Ribose) Polymerase-1 Inhibitors: Chemopotentiation and Pharmacological Studies

Christopher R. Calabrese, Michael A. Batey, Huw D. Thomas, Barbara W. Durkacz, Lan-Zhen Wang, Suzanne Kyle, Donald Skalitzky, Janke Li, Catherine Zhang, Theodore Boritzki, Karen Maegley, Alan H. Calvert, Zdenek Hostomsky, David R. Newell, Nicola J. Curtin
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (7): 2711–2718.
Published: 01 July 2003
View article titled, Identification of Potent Nontoxic Poly(ADP-Ribose) Polymerase-1 Inhibitors: <subtitle>Chemopotentiation and Pharmacological Studies</subtitle>
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Journal Articles

In Vitro and in Vivo Properties of Novel Nucleoside Transport Inhibitors with Improved Pharmacological Properties That Potentiate Antifolate Activity

Peter G. Smith, Huw D. Thomas, Hannah C. Barlow, Roger J. Griffin, Bernard T. Golding, A. Hilary Calvert, David R. Newell, Nicola J. Curtin
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (7): 2105–2113.
Published: 01 July 2001
View article titled, <em>In Vitro</em> and <em>in Vivo</em> Properties of Novel Nucleoside Transport Inhibitors with Improved Pharmacological Properties That Potentiate Antifolate Activity
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