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Journal Articles

Phase Ib Pharmacodynamic Study of the MNK Inhibitor Tomivosertib (eFT508) Combined With Paclitaxel in Patients With Refractory Metastatic Breast Cancer

Cristiano Ferrario, John Mackey, Karen A. Gelmon, Nathalie Levasseur, Poul H. Sorensen, Htoo Zarni Oo, Gian L. Negri, Veronica W.L. Tse, Sandra E. Spencer, Grace Cheng, Gregg B. Morin, Sonia del Rincon, Tiziana Cotechini, Christophe Gonçalves, Charles C.T. Hindmarch, Wilson H. Miller, Jr, Mehdi Amiri, Tayebeh Basiri, Victor Villareal-Corpuz, Sam Sperry, Kevin Gregorczyk, Gonzalo Spera, Nahum Sonenberg, Michael Pollak
Journal: Clinical Cancer Research
Clin Cancer Res OF1–OF12.
https://doi.org/10.1158/1078-0432.CCR-24-0841
Published: 31 December 2024
View article titled, Phase Ib Pharmacodynamic Study of the MNK Inhibitor Tomivosertib (eFT508) Combined With Paclitaxel in Patients With Refractory Metastatic Breast Cancer
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Includes: Supplementary data
Journal Articles

A Bifunctional PARP-HDAC Inhibitor with Activity in Ewing Sarcoma

Louise Ramos, Sarah Truong, Beibei Zhai, Jay Joshi, Fariba Ghaidi, Michael M. Lizardo, Taras Shyp, Sonia H.Y. Kung, Alireza M. Rezakhanlou, Htoo Zarni Oo, Hans Adomat, Stephane Le Bihan, Colin Collins, Jeffrey Bacha, Dennis Brown, John Langlands, Wang Shen, Nada Lallous, Poul H. Sorensen, Mads Daugaard
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (17): 3541–3553.
https://doi.org/10.1158/1078-0432.CCR-22-3897
Published: 01 September 2023
View article titled, A Bifunctional PARP-HDAC Inhibitor with Activity in Ewing Sarcoma
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Includes: Supplementary data
Journal Articles

Divergent Biological Response to Neoadjuvant Chemotherapy in Muscle-invasive Bladder Cancer

Roland Seiler, Ewan A. Gibb, Natalie Q. Wang, Htoo Zarni Oo, Hung-Ming Lam, Kim E. van Kessel, Charlotte S. Voskuilen, Brian Winters, Nicholas Erho, Mandeep M. Takhar, James Douglas, Funda Vakar-Lopez, Simon J. Crabb, Bas W.G. van Rhijn, Elisabeth E. Fransen van de Putte, Ellen C. Zwarthoff, George N. Thalmann, Elai Davicioni, Joost L. Boormans, Marc Dall'Era, Michiel S. van der Heijden, Jonathan L. Wright, Peter C. Black
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (16): 5082–5093.
https://doi.org/10.1158/1078-0432.CCR-18-1106
Published: 15 August 2019
View article titled, Divergent Biological Response to Neoadjuvant Chemotherapy in Muscle-invasive Bladder Cancer
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Includes: Supplementary data
Journal Articles

Molecular Characterization of Neuroendocrine-like Bladder Cancer

José Batista da Costa, Ewan A. Gibb, Trinity J. Bivalacqua, Yang Liu, Htoo Zarni Oo, David T. Miyamoto, Mohammed Alshalalfa, Elai Davicioni, Jonathan Wright, Marc A. Dall’Era, James Douglas, Joost L. Boormans, Michiel S. Van der Heijden, Chin-Lee Wu, Bas W.G. van Rhijn, Shilpa Gupta, Petros Grivas, Kent W. Mouw, Paari Murugan, Ladan Fazli, Seong Ra, Badrinath R. Konety, Roland Seiler, Siamak Daneshmand, Omar Y. Mian, Jason A. Efstathiou, Yair Lotan, Peter C. Black
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (13): 3908–3920.
https://doi.org/10.1158/1078-0432.CCR-18-3558
Published: 01 July 2019
View article titled, Molecular Characterization of Neuroendocrine-like Bladder Cancer
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Includes: Supplementary data
Journal Articles

Not all NOTCH Is Created Equal: The Oncogenic Role of NOTCH2 in Bladder Cancer and Its Implications for Targeted Therapy

Tetsutaro Hayashi, Kilian M. Gust, Alexander W. Wyatt, Akihiro Goriki, Wolfgang Jäger, Shannon Awrey, Na Li, Htoo Zarni Oo, Manuel Altamirano-Dimas, Ralph Buttyan, Ladan Fazli, Akio Matsubara, Peter C. Black
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (12): 2981–2992.
https://doi.org/10.1158/1078-0432.CCR-15-2360
Published: 14 June 2016
View article titled, Not all NOTCH Is Created Equal: The Oncogenic Role of NOTCH2 in Bladder Cancer and Its Implications for Targeted Therapy
Open the PDF for Not all NOTCH Is Created Equal: The Oncogenic Role of NOTCH2 in Bladder Cancer and Its Implications for Targeted Therapy in another window
Includes: Supplementary data