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Journal Articles

Phase I/II Trial of Exportin 1 Inhibitor Selinexor plus Docetaxel in Previously Treated, Advanced KRAS-Mutant Non–Small Cell Lung Cancer

Mitchell S. von Itzstein, Timothy F. Burns, Jonathan E. Dowell, Leora Horn, D. Ross Camidge, Sally J. York, Keith D. Eaton, Kelly Kyle, Farjana Fattah, Jialiang Liu, Hong Mu-Mosley, Arjun Gupta, Urooba Nadeem, Ang Gao, Song Zhang, David E. Gerber
Journal: Clinical Cancer Research
Clin Cancer Res (2025) 31 (4): 639–648.
https://doi.org/10.1158/1078-0432.CCR-24-1722
Published: 17 February 2025
View article titled, Phase I/II Trial of Exportin 1 Inhibitor Selinexor plus Docetaxel in Previously Treated, Advanced <em>KRAS</em>-Mutant Non–Small Cell Lung Cancer
Open the PDF for Phase I/II Trial of Exportin 1 Inhibitor Selinexor plus Docetaxel in Previously Treated, Advanced <em>KRAS</em>-Mutant Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Disruption of Wnt/β-Catenin Exerts Antileukemia Activity and Synergizes with FLT3 Inhibition in FLT3-Mutant Acute Myeloid Leukemia

Xuejie Jiang, Po Yee Mak, Hong Mu, Wenjing Tao, Duncan H. Mak, Steven Kornblau, Qi Zhang, Peter Ruvolo, Jared K. Burks, Weiguo Zhang, Teresa McQueen, Rongqing Pan, Hongsheng Zhou, Marina Konopleva, Jorge Cortes, Qifa Liu, Michael Andreeff, Bing Z. Carter
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (10): 2417–2429.
https://doi.org/10.1158/1078-0432.CCR-17-1556
Published: 14 May 2018
View article titled, Disruption of Wnt/β-Catenin Exerts Antileukemia Activity and Synergizes with FLT3 Inhibition in <em>FLT3</em>-Mutant Acute Myeloid Leukemia
Open the PDF for Disruption of Wnt/β-Catenin Exerts Antileukemia Activity and Synergizes with FLT3 Inhibition in <em>FLT3</em>-Mutant Acute Myeloid Leukemia in another window
Includes: Supplementary data
Journal Articles

Macrophages Facilitate Resistance to Anti-VEGF Therapy by Altered VEGFR Expression

Heather J. Dalton, Sunila Pradeep, Michael McGuire, Yared Hailemichael, Shaolin MA, Yasmin Lyons, Guillermo N. Armaiz-Pena, Rebecca A. Previs, Jean Marie Hansen, Rajesha Rupaimoole, Vianey Gonzalez-Villasana, Min Soon Cho, Sherry Y. Wu, Lingegowda S. Mangala, Nicholas B. Jennings, Wei Hu, Robert Langley, Hong Mu, Michael Andreeff, Menashe Bar-Eli, Willem Overwijk, Prahlad Ram, Gabriel Lopez-Berestein, Robert L. Coleman, Anil K. Sood
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (22): 7034–7046.
https://doi.org/10.1158/1078-0432.CCR-17-0647
Published: 14 November 2017
View article titled, Macrophages Facilitate Resistance to Anti-VEGF Therapy by Altered VEGFR Expression
Open the PDF for Macrophages Facilitate Resistance to Anti-VEGF Therapy by Altered VEGFR Expression in another window
Includes: Supplementary data
Journal Articles

Antileukemia Efficacy and Mechanisms of Action of SL-101, a Novel Anti-CD123 Antibody Conjugate, in Acute Myeloid Leukemia

Lina Han, Jeffrey L. Jorgensen, Chris Brooks, Ce Shi, Qi Zhang, Graciela M. Nogueras González, Antonio Cavazos, Rongqing Pan, Hong Mu, Sa A. Wang, Jin Zhou, Gheath AI-Atrash, Stefan O. Ciurea, Mike Rettig, John F. DiPersio, Jorge Cortes, Xuelin Huang, Hagop M. Kantarjian, Michael Andreeff, Farhad Ravandi, Marina Konopleva
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (13): 3385–3395.
https://doi.org/10.1158/1078-0432.CCR-16-1904
Published: 02 July 2017
View article titled, Antileukemia Efficacy and Mechanisms of Action of SL-101, a Novel Anti-CD123 Antibody Conjugate, in Acute Myeloid Leukemia
Open the PDF for Antileukemia Efficacy and Mechanisms of Action of SL-101, a Novel Anti-CD123 Antibody Conjugate, in Acute Myeloid Leukemia in another window
Includes: Supplementary data
Journal Articles

Hypoxia-Activated Prodrug TH-302 Targets Hypoxic Bone Marrow Niches in Preclinical Leukemia Models

Juliana Benito, Marc S. Ramirez, Niki Zacharias Millward, Juliana Velez, Karine G. Harutyunyan, Hongbo Lu, Yue-xi Shi, Polina Matre, Rodrigo Jacamo, Helen Ma, Sergej Konoplev, Teresa McQueen, Andrei Volgin, Marina Protopopova, Hong Mu, Jaehyuk Lee, Pratip K. Bhattacharya, Joseph R. Marszalek, R. Eric Davis, James A. Bankson, Jorge E. Cortes, Charles P. Hart, Michael Andreeff, Marina Konopleva
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (7): 1687–1698.
https://doi.org/10.1158/1078-0432.CCR-14-3378
Published: 31 March 2016
View article titled, Hypoxia-Activated Prodrug TH-302 Targets Hypoxic Bone Marrow Niches in Preclinical Leukemia Models
Open the PDF for Hypoxia-Activated Prodrug TH-302 Targets Hypoxic Bone Marrow Niches in Preclinical Leukemia Models in another window
Includes: Supplementary data