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Journal Articles

Editor's Note: Identification of Insulin-Like Growth Factor Binding Protein-3 as a Farnesyl Transferase Inhibitor SCH66336-Induced Negative Regulator of Angiogenesis in Head and Neck Squamous Cell Carcinoma

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Seung-Hyun Oh, Woo-Young Kim, Jai-Hyun Kim, Maher N. Younes, Adel K. El-Naggar, Jeffrey N. Myers, Merril Kies, Pinchas Cohen, Fadlo Khuri, Waun K. Hong, Ho-Young Lee
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (15): 4861.
https://doi.org/10.1158/1078-0432.CCR-19-2054
Published: 01 August 2019
View articletitled, Editor's Note: Identification of Insulin-Like Growth Factor Binding Protein-3 as a Farnesyl Transferase Inhibitor SCH66336-Induced Negative Regulator of Angiogenesis in Head and Neck Squamous Cell Carcinoma
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Journal Articles

Essential Role of DNA Methyltransferase 1–mediated Transcription of Insulin-like Growth Factor 2 in Resistance to Histone Deacetylase Inhibitors

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Hye-Young Min, Su-Chan Lee, Jong Kyu Woo, Hyun Jin Jung, Kwan Hee Park, Hae Min Jeong, Seung Yeob Hyun, Jaebeom Cho, Wooin Lee, Ji Eun Park, So Jung Kwon, Hyo-Jong Lee, Xiao Ni, Young Kee Shin, Faye M. Johnson, Madeleine Duvic, Ho-Young Lee
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (5): 1299–1311.
https://doi.org/10.1158/1078-0432.CCR-16-0534
Published: 28 February 2017
View articletitled, Essential Role of DNA Methyltransferase 1–mediated Transcription of Insulin-like Growth Factor 2 in Resistance to Histone Deacetylase Inhibitors
Open the PDF for Essential Role of DNA Methyltransferase 1–mediated Transcription of Insulin-like Growth Factor 2 in Resistance to Histone Deacetylase Inhibitors in another window
Includes: Supplementary data
Journal Articles

Insulin-like Growth Factor-I Receptor Signaling Pathway Induces Resistance to the Apoptotic Activities of SCH66336 (Lonafarnib) through Akt/Mammalian Target of Rapamycin–Mediated Increases in Survivin Expression

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Seung Hyun Oh, Quanri Jin, Edward S. Kim, Fadlo R. Khuri, Ho-Young Lee
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (5): 1581–1589.
https://doi.org/10.1158/1078-0432.CCR-07-0952
Published: 03 March 2008
View articletitled, Insulin-like Growth Factor-I Receptor Signaling Pathway Induces Resistance to the Apoptotic Activities of SCH66336 (Lonafarnib) through Akt/Mammalian Target of Rapamycin–Mediated Increases in Survivin Expression
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Journal Articles

Implication of the Insulin-like Growth Factor-IR Pathway in the Resistance of Non–small Cell Lung Cancer Cells to Treatment with Gefitinib

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Floriana Morgillo, Woo-Young Kim, Edward S. Kim, Fortunato Ciardiello, Waun Ki Hong, Ho-Young Lee
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (9): 2795–2803.
https://doi.org/10.1158/1078-0432.CCR-06-2077
Published: 01 May 2007
View articletitled, Implication of the Insulin-like Growth Factor-IR Pathway in the Resistance of Non–small Cell Lung Cancer Cells to Treatment with Gefitinib
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Journal Articles

Identification of Insulin-Like Growth Factor Binding Protein-3 as a Farnesyl Transferase Inhibitor SCH66336-Induced Negative Regulator of Angiogenesis in Head and Neck Squamous Cell Carcinoma

Free
Seung-Hyun Oh, Woo-Young Kim, Jai-Hyun Kim, Maher N. Younes, Adel K. El-Naggar, Jeffrey N. Myers, Merril Kies, Pinchas Cohen, Fadlo Khuri, Waun K. Hong, Ho-Young Lee
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (2): 653–661.
https://doi.org/10.1158/1078-0432.CCR-05-1725
Published: 20 January 2006
View articletitled, Identification of Insulin-Like Growth Factor Binding Protein-3 as a Farnesyl Transferase Inhibitor SCH66336-Induced Negative Regulator of Angiogenesis in Head and Neck Squamous Cell Carcinoma
Open the PDF for Identification of Insulin-Like Growth Factor Binding Protein-3 as a Farnesyl Transferase Inhibitor SCH66336-Induced Negative Regulator of Angiogenesis in Head and Neck Squamous Cell Carcinoma in another window
Journal Articles

Response of Non–Small Cell Lung Cancer Cells to the Inhibitors of Phosphatidylinositol 3-Kinase/Akt- and MAPK Kinase 4/c-Jun NH2-Terminal Kinase Pathways: An Effective Therapeutic Strategy for Lung Cancer

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Ho-Young Lee, Seung-Hyun Oh, Young-Ah Suh, Jin Hyen Baek, Vali Papadimitrakopoulou, Suyun Huang, Waun Ki Hong
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (16): 6065–6074.
https://doi.org/10.1158/1078-0432.CCR-05-0009
Published: 22 August 2005
View articletitled, Response of Non–Small Cell Lung Cancer Cells to the Inhibitors of Phosphatidylinositol 3-Kinase/Akt- and MAPK Kinase 4/c-Jun NH2-Terminal Kinase Pathways: An Effective Therapeutic Strategy for Lung Cancer
Open the PDF for Response of Non–Small Cell Lung Cancer Cells to the Inhibitors of Phosphatidylinositol 3-Kinase/Akt- and MAPK Kinase 4/c-Jun NH2-Terminal Kinase Pathways: An Effective Therapeutic Strategy for Lung Cancer in another window
Journal Articles

9-cis-Retinoic Acid Treatment Increases Serum Concentrations of α-Tocopherol in Former Smokers

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Ji-Youn Han, Diane D. Liu, J. Jack Lee, Jonathan Kurie, Reuben Lotan, Waun K. Hong, Ho-Young Lee
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (6): 2305–2311.
https://doi.org/10.1158/1078-0432.CCR-04-2074
Published: 23 March 2005
View articletitled, 9-cis-Retinoic Acid Treatment Increases Serum Concentrations of α-Tocopherol in Former Smokers
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Journal Articles

Deguelin-Induced Inhibition of Cyclooxygenase-2 Expression in Human Bronchial Epithelial Cells

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Ho-Young Lee, Young-Ah Suh, Jerome W. Kosmeder, John M. Pezzuto, Waun Ki Hong, Jonathan M. Kurie
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (3): 1074–1079.
https://doi.org/10.1158/1078-0432.CCR-0833-3
Published: 10 February 2004
View articletitled, Deguelin-Induced Inhibition of Cyclooxygenase-2 Expression in Human Bronchial Epithelial Cells
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Journal Articles

Clinical Significance of Insulin-like Growth Factor-binding Protein-3 Expression in Stage I Non-Small Cell Lung Cancer

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Yoon Soo Chang, Koo Gong, Shihua Sun, Diane Liu, Adel K. El-Naggar, Fadlo R. Khuri, Waun Ki Hong, Ho-Young Lee
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (12): 3796–3802.
Published: 01 December 2002
View articletitled, Clinical Significance of Insulin-like Growth Factor-binding Protein-3 Expression in Stage I Non-Small Cell Lung Cancer
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Journal Articles

Correlation between Insulin-like Growth Factor-binding Protein-3 Promoter Methylation and Prognosis of Patients with Stage I Non-Small Cell Lung Cancer

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Yoon Soo Chang, Luo Wang, Diane Liu, Li Mao, Waun Ki Hong, Fadlo R. Khuri, Ho-Young Lee
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (12): 3669–3675.
Published: 01 December 2002
View articletitled, Correlation between Insulin-like Growth Factor-binding Protein-3 Promoter Methylation and Prognosis of Patients with Stage I Non-Small Cell Lung Cancer
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Journal Articles

Inhibition of Oncogenic K-ras Signaling by Aerosolized Gene Delivery in a Mouse Model of Human Lung Cancer

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Ho-Young Lee, Young-Ah Suh, Janet I. Lee, Khaled A. Hassan, Li Mao, Thomas Force, Brian E. Gilbert, Tyler Jacks, Jonathan M. Kurie
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (9): 2970–2975.
Published: 01 September 2002
View articletitled, Inhibition of Oncogenic K-ras Signaling by Aerosolized Gene Delivery in a Mouse Model of Human Lung Cancer
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Journal Articles

Lack of PTEN Expression in Non-Small Cell Lung Cancer Could Be Related to Promoter Methylation

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Jean-Charles Soria, Ho-Young Lee, Janet I. Lee, Luo Wang, Jean-Pierre Issa, Bonnie L. Kemp, Diane D. Liu, Jonathan M. Kurie, Li Mao, Fadlo R. Khuri
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (5): 1178–1184.
Published: 01 May 2002
View articletitled, Lack of PTEN Expression in Non-Small Cell Lung Cancer Could Be Related to Promoter Methylation
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