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Journal Articles

EpiPanGI Dx: A Cell-free DNA Methylation Fingerprint for the Early Detection of Gastrointestinal Cancers

Raju Kandimalla, Jianfeng Xu, Alexander Link, Takatoshi Matsuyama, Kensuke Yamamura, M. Iqbal Parker, Hiroyuki Uetake, Francesc Balaguer, Erkut Borazanci, Susan Tsai, Douglas Evans, Stephen J. Meltzer, Hideo Baba, Randall Brand, Daniel Von Hoff, Wei Li, Ajay Goel
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (22): 6135–6144.
https://doi.org/10.1158/1078-0432.CCR-21-1982
Published: 15 November 2021
View articletitled, EpiPanGI Dx: A Cell-free DNA Methylation Fingerprint for the Early Detection of Gastrointestinal Cancers
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Includes: Supplementary data
Journal Articles

A 15-Gene Immune, Stromal, and Proliferation Gene Signature that Significantly Associates with Poor Survival in Patients with Pancreatic Ductal Adenocarcinoma

Raju Kandimalla, Hideo Tomihara, Jasjit K. Banwait, Kensuke Yamamura, Gagandeep Singh, Hideo Baba, Ajay Goel
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (14): 3641–3648.
https://doi.org/10.1158/1078-0432.CCR-19-4044
Published: 15 July 2020
View articletitled, A 15-Gene Immune, Stromal, and Proliferation Gene Signature that Significantly Associates with Poor Survival in Patients with Pancreatic Ductal Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Intratumoral Fusobacterium Nucleatum Levels Predict Therapeutic Response to Neoadjuvant Chemotherapy in Esophageal Squamous Cell Carcinoma

Kensuke Yamamura, Daisuke Izumi, Raju Kandimalla, Fuminori Sonohara, Yoshifumi Baba, Naoya Yoshida, Yasuhiro Kodera, Hideo Baba, Ajay Goel
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (20): 6170–6179.
https://doi.org/10.1158/1078-0432.CCR-19-0318
Published: 15 October 2019
View articletitled, Intratumoral Fusobacterium Nucleatum Levels Predict Therapeutic Response to Neoadjuvant Chemotherapy in Esophageal Squamous Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Molecular Profiling of Appendiceal Adenocarcinoma and Comparison with Right-sided and Left-sided Colorectal Cancer

Ryuma Tokunaga, Joanne Xiu, Curtis Johnston, Richard M. Goldberg, Philip A. Philip, Andreas Seeber, Madiha Naseem, Jae Ho Lo, Hiroyuki Arai, Francesca Battaglin, Alberto Puccini, Martin D. Berger, Shivani Soni, Wu Zhang, Jimmy J. Hwang, Anthony F. Shields, John L. Marshall, Hideo Baba, W. Michael Korn, Heinz-Josef Lenz
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (10): 3096–3103.
https://doi.org/10.1158/1078-0432.CCR-18-3388
Published: 15 May 2019
View articletitled, Molecular Profiling of Appendiceal Adenocarcinoma and Comparison with Right-sided and Left-sided Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Amplification of Wild-type KRAS Imparts Resistance to Crizotinib in MET Exon 14 Mutant Non–Small Cell Lung Cancer

Magda Bahcall, Mark M. Awad, Lynette M. Sholl, Frederick H. Wilson, Man Xu, Stephen Wang, Sangeetha Palakurthi, Jihyun Choi, Elena V. Ivanova, Giulia C. Leonardi, Bryan C. Ulrich, Cloud P. Paweletz, Paul T. Kirschmeier, Masayuki Watanabe, Hideo Baba, Mizuki Nishino, Rebecca J. Nagy, Richard B. Lanman, Marzia Capelletti, Emily S. Chambers, Amanda J. Redig, Paul A. VanderLaan, Daniel B. Costa, Yu Imamura, Pasi A. Jänne
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (23): 5963–5976.
https://doi.org/10.1158/1078-0432.CCR-18-0876
Published: 03 December 2018
View articletitled, Amplification of Wild-type KRAS Imparts Resistance to Crizotinib in MET Exon 14 Mutant Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Human Microbiome Fusobacterium Nucleatum in Esophageal Cancer Tissue Is Associated with Prognosis

Kensuke Yamamura, Yoshifumi Baba, Shigeki Nakagawa, Kosuke Mima, Keisuke Miyake, Kenichi Nakamura, Hiroshi Sawayama, Koichi Kinoshita, Takatsugu Ishimoto, Masaaki Iwatsuki, Yasuo Sakamoto, Yoichi Yamashita, Naoya Yoshida, Masayuki Watanabe, Hideo Baba
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (22): 5574–5581.
https://doi.org/10.1158/1078-0432.CCR-16-1786
Published: 14 November 2016
View articletitled, Human Microbiome Fusobacterium Nucleatum in Esophageal Cancer Tissue Is Associated with Prognosis
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Includes: Supplementary data
Journal Articles

Molecular Pathways: Cachexia Signaling—A Targeted Approach to Cancer Treatment

Yuji Miyamoto, Diana L. Hanna, Wu Zhang, Hideo Baba, Heinz-Josef Lenz
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16): 3999–4004.
https://doi.org/10.1158/1078-0432.CCR-16-0495
Published: 14 August 2016
View articletitled, Molecular Pathways: Cachexia Signaling—A Targeted Approach to Cancer Treatment
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Journal Articles

MicroRNA MIR21 (miR-21) and PTGS2 Expression in Colorectal Cancer and Patient Survival

Kosuke Mima, Reiko Nishihara, Juhong Yang, Ruoxu Dou, Yohei Masugi, Yan Shi, Annacarolina da Silva, Yin Cao, Mingyang Song, Jonathan Nowak, Mancang Gu, Wanwan Li, Teppei Morikawa, Xuehong Zhang, Kana Wu, Hideo Baba, Edward L. Giovannucci, Jeffrey A. Meyerhardt, Andrew T. Chan, Charles S. Fuchs, Zhi Rong Qian, Shuji Ogino
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (15): 3841–3848.
https://doi.org/10.1158/1078-0432.CCR-15-2173
Published: 31 July 2016
View articletitled, MicroRNA MIR21 (miR-21) and PTGS2 Expression in Colorectal Cancer and Patient Survival
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Includes: Supplementary data
Journal Articles

LINE-1 Hypomethylation, DNA Copy Number Alterations, and CDK6 Amplification in Esophageal Squamous Cell Carcinoma

Yoshifumi Baba, Masayuki Watanabe, Asuka Murata, Hironobu Shigaki, Keisuke Miyake, Takatsugu Ishimoto, Masaaki Iwatsuki, Shiro Iwagami, Naoya Yoshida, Eiji Oki, Kentaro Sakamaki, Mitsuyoshi Nakao, Hideo Baba
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (5): 1114–1124.
https://doi.org/10.1158/1078-0432.CCR-13-1645
Published: 02 March 2014
View articletitled, LINE-1 Hypomethylation, DNA Copy Number Alterations, and CDK6 Amplification in Esophageal Squamous Cell Carcinoma
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Includes: Supplementary data
Journal Articles

PIK3CA Mutation Is Associated with a Favorable Prognosis among Patients with Curatively Resected Esophageal Squamous Cell Carcinoma

Hironobu Shigaki, Yoshifumi Baba, Masayuki Watanabe, Asuka Murata, Takatsugu Ishimoto, Masaaki Iwatsuki, Shiro Iwagami, Katsuhiko Nosho, Hideo Baba
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (9): 2451–2459.
https://doi.org/10.1158/1078-0432.CCR-12-3559
Published: 30 April 2013
View articletitled, PIK3CA Mutation Is Associated with a Favorable Prognosis among Patients with Curatively Resected Esophageal Squamous Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Enhancement of Human Cancer Cell Motility and Invasiveness by Anaphylatoxin C5a via Aberrantly Expressed C5a Receptor (CD88)

Hidetoshi Nitta, Yoshihiro Wada, Yoshiaki Kawano, Yoji Murakami, Atsushi Irie, Keisuke Taniguchi, Ken Kikuchi, Gen Yamada, Kentaro Suzuki, Jiro Honda, Masayo Wilson-Morifuji, Norie Araki, Masatoshi Eto, Hideo Baba, Takahisa Imamura
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (8): 2004–2013.
https://doi.org/10.1158/1078-0432.CCR-12-1204
Published: 15 April 2013
View articletitled, Enhancement of Human Cancer Cell Motility and Invasiveness by Anaphylatoxin C5a via Aberrantly Expressed C5a Receptor (CD88)
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Includes: Multimedia, Supplementary data
Journal Articles

MicroRNA-21 Regulates the Proliferation and Invasion in Esophageal Squamous Cell Carcinoma

Yukiharu Hiyoshi, Hidenobu Kamohara, Ryuichi Karashima, Nobutaka Sato, Yu Imamura, Youhei Nagai, Naoya Yoshida, Eiichiro Toyama, Naoko Hayashi, Masayuki Watanabe, Hideo Baba
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (6): 1915–1922.
https://doi.org/10.1158/1078-0432.CCR-08-2545
Published: 16 March 2009
View articletitled, MicroRNA-21 Regulates the Proliferation and Invasion in Esophageal Squamous Cell Carcinoma
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Journal Articles

Identification of a Novel Tumor-Associated Antigen, Cadherin 3/P-Cadherin, as a Possible Target for Immunotherapy of Pancreatic, Gastric, and Colorectal Cancers

Katsunori Imai, Shinya Hirata, Atsushi Irie, Satoru Senju, Yoshiaki Ikuta, Kazunori Yokomine, Michiko Harao, Mitsuhiro Inoue, Takuya Tsunoda, Shuichi Nakatsuru, Hidewaki Nakagawa, Yusuke Nakamura, Hideo Baba, Yasuharu Nishimura
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (20): 6487–6495.
https://doi.org/10.1158/1078-0432.CCR-08-1086
Published: 16 October 2008
View articletitled, Identification of a Novel Tumor-Associated Antigen, Cadherin 3/P-Cadherin, as a Possible Target for Immunotherapy of Pancreatic, Gastric, and Colorectal Cancers
Open the PDF for Identification of a Novel Tumor-Associated Antigen, Cadherin 3/P-Cadherin, as a Possible Target for Immunotherapy of Pancreatic, Gastric, and Colorectal Cancers in another window
Includes: Supplementary data
Journal Articles

Identification of HLA-A2- or HLA-A24-Restricted CTL Epitopes Possibly Useful for Glypican-3-Specific Immunotherapy of Hepatocellular Carcinoma

Hiroyuki Komori, Tetsuya Nakatsura, Satoru Senju, Yoshihiro Yoshitake, Yutaka Motomura, Yoshiaki Ikuta, Daiki Fukuma, Kazunori Yokomine, Michiko Harao, Toru Beppu, Masanori Matsui, Toshihiko Torigoe, Noriyuki Sato, Hideo Baba, Yasuharu Nishimura
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (9): 2689–2697.
https://doi.org/10.1158/1078-0432.CCR-05-2267
Published: 04 May 2006
View articletitled, Identification of HLA-A2- or HLA-A24-Restricted CTL Epitopes Possibly Useful for Glypican-3-Specific Immunotherapy of Hepatocellular Carcinoma
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Journal Articles

Highly Sensitive Detection of Melanoma at an Early Stage Based on the Increased Serum Secreted Protein Acidic and Rich in Cysteine and Glypican-3 Levels

Yoshiaki Ikuta, Tetsuya Nakatsura, Toshiro Kageshita, Satoshi Fukushima, Shosuke Ito, Kazumasa Wakamatsu, Hideo Baba, Yasuharu Nishimura
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (22): 8079–8088.
https://doi.org/10.1158/1078-0432.CCR-05-1074
Published: 18 November 2005
View articletitled, Highly Sensitive Detection of Melanoma at an Early Stage Based on the Increased Serum Secreted Protein Acidic and Rich in Cysteine and Glypican-3 Levels
Open the PDF for Highly Sensitive Detection of Melanoma at an Early Stage Based on the Increased Serum Secreted Protein Acidic and Rich in Cysteine and Glypican-3 Levels in another window
Journal Articles

Clinicopathological Features and Overexpression of Matrix Metalloproteinases in Intramucosal Gastric Carcinoma with Lymph Node Metastasis

Akira Kabashima, Yoshihiko Maehara, Yoshihiro Kakeji, Hideo Baba, Tadashi Koga, Keizo Sugimachi
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (9): 3581–3584.
Published: 01 September 2000
View articletitled, Clinicopathological Features and Overexpression of Matrix Metalloproteinases in Intramucosal Gastric Carcinoma with Lymph Node Metastasis
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