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Herbert I. Hurwitz
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Journal Articles

Predictive Biomarkers of Overall Survival in Patients with Metastatic Renal Cell Carcinoma Treated with IFNα ± Bevacizumab: Results from CALGB 90206 (Alliance)

Andrew B. Nixon, Susan Halabi, Yingmiao Liu, Mark D. Starr, John C. Brady, Ivo Shterev, Bin Luo, Herbert I. Hurwitz, Phillip G. Febbo, Brian I. Rini, Himisha Beltran, Eric J. Small, Michael J. Morris, Daniel J. George
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (13): 2771–2778.
DOI: https://doi.org/10.1158/1078-0432.CCR-21-2386
Published: 01 July 2022
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Includes: Supplementary data
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Plasma Protein Biomarkers in Advanced or Metastatic Colorectal Cancer Patients Receiving Chemotherapy With Bevacizumab or Cetuximab: Results from CALGB 80405 (Alliance)

Andrew B. Nixon, Alexander B. Sibley, Yingmiao Liu, Ace J. Hatch, Chen Jiang, Flora Mulkey, Mark D. Starr, John C. Brady, Donna Niedzwiecki, Alan P. Venook, Luis Baez-Diaz, Heinz-Josef Lenz, Bert H. O'Neil, Federico Innocenti, Jeffrey A. Meyerhardt, Eileen M. O'Reilly, Kouros Owzar, Herbert I. Hurwitz
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (13): 2779–2788.
DOI: https://doi.org/10.1158/1078-0432.CCR-21-2389
Published: 01 July 2022
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Disease Monitoring Using Post-induction Circulating Tumor DNA Analysis Following First-Line Therapy in Patients with Metastatic Colorectal Cancer

Xiaoju Max Ma, Johanna C. Bendell, Herbert I. Hurwitz, Christine Ju, John J. Lee, Alex Lovejoy, Christoph Mancao, Alan Nicholas, Richard Price, Nicolas Sommer, Nalin Tikoo, Lijing Yao, Stephanie J. Yaung, John F. Palma
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (15): 4010–4017.
DOI: https://doi.org/10.1158/1078-0432.CCR-19-1209
Published: 03 August 2020
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Predictive Blood-Based Biomarkers in Patients with Epithelial Ovarian Cancer Treated with Carboplatin and Paclitaxel with or without Bevacizumab: Results from GOG-0218

Angeles Alvarez Secord, Kirsten Bell Burdett, Kouros Owzar, David Tritchler, Alexander B. Sibley, Yingmiao Liu, Mark D. Starr, J. Chris Brady, Heather A. Lankes, Herbert I. Hurwitz, Robert S. Mannel, Krishnansu S. Tewari, David M. O'Malley, Heidi Gray, Jamie N. Bakkum-Gamez, Keiichi Fujiwara, Matthew Boente, Wei Deng, Robert A. Burger, Michael J. Birrer, Andrew B. Nixon
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (6): 1288–1296.
DOI: https://doi.org/10.1158/1078-0432.CCR-19-0226
Published: 13 March 2020
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A Randomized, Double-Blind, Placebo-Controlled Phase II Study of the Efficacy and Safety of Monotherapy Ontuxizumab (MORAb-004) Plus Best Supportive Care in Patients with Chemorefractory Metastatic Colorectal Cancer

Axel Grothey, Jonathan R. Strosberg, Lindsay A. Renfro, Herbert I. Hurwitz, John L. Marshall, Howard Safran, Michael J. Guarino, George P. Kim, J.R. Hecht, Susan C. Weil, John Heyburn, Wenquan Wang, Charles Schweizer, Daniel J. O'Shannessy, Luis Alberto Diaz, Jr
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (2): 316–325.
DOI: https://doi.org/10.1158/1078-0432.CCR-17-1558
Published: 15 January 2018
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Journal Articles

Direct Evidence of Target Inhibition with Anti-VEGF, EGFR, and mTOR Therapies in a Clinical Model of Wound Healing

Jingquan Jia, Andrew E. Dellinger, Eric S. Weiss, Anuradha Bulusu, Christel Rushing, Haiyan Li, Leigh A. Howard, Neal Kaplan, Herbert Pang, Herbert I. Hurwitz, Andrew B. Nixon
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (15): 3442–3452.
DOI: https://doi.org/10.1158/1078-0432.CCR-14-2819
Published: 02 August 2015
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Gene Expression Markers of Efficacy and Resistance to Cetuximab Treatment in Metastatic Colorectal Cancer: Results from CALGB 80203 (Alliance)

Stephanie M. Cushman, Chen Jiang, Ace J. Hatch, Ivo Shterev, Alexander B. Sibley, Donna Niedzwiecki, Alan P. Venook, Kouros Owzar, Herbert I. Hurwitz, Andrew B. Nixon
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (5): 1078–1086.
DOI: https://doi.org/10.1158/1078-0432.CCR-14-2313
Published: 01 March 2015
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Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of Dalantercept, an Activin Receptor–like Kinase-1 Ligand Trap, in Patients with Advanced Cancer

Johanna C. Bendell, Michael S. Gordon, Herbert I. Hurwitz, Suzanne F. Jones, David S. Mendelson, Gerard C. Blobe, Neeraj Agarwal, Carolyn H. Condon, Dawn Wilson, Amelia E. Pearsall, Yijun Yang, Ty McClure, Kenneth M. Attie, Matthew L. Sherman, Sunil Sharma
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2014) 20 (2): 480–489.
DOI: https://doi.org/10.1158/1078-0432.CCR-13-1840
Published: 16 January 2014
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Includes: Supplementary data
Journal Articles

Prognostic and Predictive Blood-Based Biomarkers in Patients with Advanced Pancreatic Cancer: Results from CALGB80303 (Alliance)

Andrew B. Nixon, Herbert Pang, Mark D. Starr, Paula N. Friedman, Monica M. Bertagnolli, Hedy L. Kindler, Richard M. Goldberg, Alan P. Venook, Herbert I. Hurwitz, for the Alliance for Clinical Trials In Oncology
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (24): 6957–6966.
DOI: https://doi.org/10.1158/1078-0432.CCR-13-0926
Published: 16 December 2013
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A Phase I First-in-Human Study of TRC105 (Anti-Endoglin Antibody) in Patients with Advanced Cancer

Lee S. Rosen, Herbert I. Hurwitz, Michael K. Wong, Jonathan Goldman, David S. Mendelson, William D. Figg, Shawn Spencer, Bonne J. Adams, Delia Alvarez, Ben K. Seon, Charles P. Theuer, Bryan R. Leigh, Michael S. Gordon
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (17): 4820–4829.
DOI: https://doi.org/10.1158/1078-0432.CCR-12-0098
Published: 30 August 2012
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Complete Longitudinal Analyses of the Randomized, Placebo-Controlled, Phase III Trial of Sunitinib in Patients with Gastrointestinal Stromal Tumor following Imatinib Failure

George D. Demetri, Christopher R. Garrett, Patrick Schöffski, Manisha H. Shah, Jaap Verweij, Serge Leyvraz, Herbert I. Hurwitz, Antonio Lopez Pousa, Axel Le Cesne, David Goldstein, Luis Paz-Ares, Jean-Yves Blay, Grant A. McArthur, Qiang (Casey) Xu, Xin Huang, Charles S. Harmon, Vanessa Tassell, Darrel P. Cohen, Paolo G. Casali
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (11): 3170–3179.
DOI: https://doi.org/10.1158/1078-0432.CCR-11-3005
Published: 31 May 2012
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Includes: Supplementary data
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Phase I Safety, Pharmacokinetics, and Inhibition of Src Activity Study of Saracatinib in Patients with Solid Tumors

José Baselga, Andres Cervantes, Erika Martinelli, Isabel Chirivella, Klaas Hoekman, Herbert I. Hurwitz, Duncan I. Jodrell, Paul Hamberg, Esther Casado, Paul Elvin, Alan Swaisland, Renee Iacona, Josep Tabernero
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (19): 4876–4883.
DOI: https://doi.org/10.1158/1078-0432.CCR-10-0748
Published: 29 September 2010
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Journal Articles

Voreloxin, a First-in-Class Anticancer Quinolone Derivative, in Relapsed/Refractory Solid Tumors: A Report on Two Dosing Schedules

Ranjana H. Advani, Herbert I. Hurwitz, Michael S. Gordon, Scot W. Ebbinghaus, David S. Mendelson, Heather A. Wakelee, Ute Hoch, Jeffrey A. Silverman, Nancy A. Havrilla, Craig J. Berman, Judith A. Fox, Roberta S. Allen, Daniel C. Adelman
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (7): 2167–2175.
DOI: https://doi.org/10.1158/1078-0432.CCR-09-2236
Published: 31 March 2010
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Phase I Trial of Pazopanib in Patients with Advanced Cancer

Herbert I. Hurwitz, Afshin Dowlati, Shermini Saini, Shawna Savage, A. Benjamin Suttle, Diana M. Gibson, Jeffrey P. Hodge, Elmar M. Merkle, Lini Pandite
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (12): 4220–4227.
DOI: https://doi.org/10.1158/1078-0432.CCR-08-2740
Published: 15 June 2009
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Reduction of Wound Angiogenesis in Patients Treated with BMS-275291, a Broad Spectrum Matrix Metalloproteinase Inhibitor

A. Craig Lockhart, Rod D. Braun, Daohai Yu, Joel R. Ross, Mark W. Dewhirst, Jeffrey S. Humphrey, Seth Thompson, Kathleen M. Williams, Bruce Klitzman, Fan Yuan, James M. Grichnik, Alan D. Proia, Delina A. Conway, Herbert I. Hurwitz
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (2): 586–593.
Published: 01 February 2003
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