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Journal Articles

Differential Survival and Therapy Benefit of Patients with Breast Cancer Are Characterized by Distinct Epithelial and Immune Cell Microenvironments

Lennart Kester, Danielle Seinstra, Annelot G.J. van Rossum, Claire Vennin, Marlous Hoogstraat, Daphne van der Velden, Mark Opdam, Erik van Werkhoven, Kerstin Hahn, Iris Nederlof, Ester H. Lips, Ingrid A.M. Mandjes, A. Elise van Leeuwen-Stok, Sander Canisius, Harm van Tinteren, Alex L.T. Imholz, Johanneke E.A. Portielje, Monique E.M.M. Bos, Sandra D. Bakker, Emiel J. Rutgers, Hugo M. Horlings, Jelle Wesseling, Emile E. Voest, Lodewyk F.A. Wessels, Marleen Kok, Hendrika M. Oosterkamp, Alexander van Oudenaarden, Sabine C. Linn, Jacco van Rheenen
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (5): 960–971.
https://doi.org/10.1158/1078-0432.CCR-21-1442
Published: 01 March 2022
View article titled, Differential Survival and Therapy Benefit of Patients with Breast Cancer Are Characterized by Distinct Epithelial and Immune Cell Microenvironments
Open the PDF for Differential Survival and Therapy Benefit of Patients with Breast Cancer Are Characterized by Distinct Epithelial and Immune Cell Microenvironments in another window
Includes: Supplementary data
Journal Articles

POSEIDON Trial Phase 1b Results: Safety, Efficacy and Circulating Tumor DNA Response of the Beta Isoform-Sparing PI3K Inhibitor Taselisib (GDC-0032) Combined with Tamoxifen in Hormone Receptor Positive Metastatic Breast Cancer Patients

Richard D. Baird, Annelot G.J. van Rossum, Mafalda Oliveira, Karin Beelen, Meiling Gao, Mariette Schrier, Ingrid A.M. Mandjes, Javier Garcia-Corbacho, Anne-Laure Vallier, Greig Dougall, Erik van Werkhoven, Constanza Linossi, Sanjeev Kumar, Harm van Tinteren, Maurizio Callari, Emma Beddowes, José-Manuel Perez-Garcia, Hilde Rosing, Else Platte, Petra Nederlof, Margaret Schot, Aurelia de Vries Schultink, René Bernards, Cristina Saura, William Gallagher, Javier Cortès, Carlos Caldas, Sabine C. Linn
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (22): 6598–6605.
https://doi.org/10.1158/1078-0432.CCR-19-0508
Published: 15 November 2019
View article titled, POSEIDON Trial Phase 1b Results: Safety, Efficacy and Circulating Tumor DNA Response of the Beta Isoform-Sparing PI3K Inhibitor Taselisib (GDC-0032) Combined with Tamoxifen in Hormone Receptor Positive Metastatic Breast Cancer Patients
Open the PDF for POSEIDON Trial Phase 1b Results: Safety, Efficacy and Circulating Tumor DNA Response of the Beta Isoform-Sparing PI3K Inhibitor Taselisib (GDC-0032) Combined with Tamoxifen in Hormone Receptor Positive Metastatic Breast Cancer Patients in another window
Includes: Supplementary data
Journal Articles

Angiogenesis- and Hypoxia-Associated Proteins as Early Indicators of the Outcome in Patients with Metastatic Breast Cancer Given First-Line Bevacizumab-Based Therapy

Siu W. Lam, Nienke M. Nota, Agnes Jager, Monique M.E.M. Bos, Joan van den Bosch, Ankie M.T. van der Velden, Johanneke E.A. Portielje, Aafke H. Honkoop, Harm van Tinteren, Epie Boven
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (7): 1611–1620.
https://doi.org/10.1158/1078-0432.CCR-15-1005
Published: 31 March 2016
View article titled, Angiogenesis- and Hypoxia-Associated Proteins as Early Indicators of the Outcome in Patients with Metastatic Breast Cancer Given First-Line Bevacizumab-Based Therapy
Open the PDF for Angiogenesis- and Hypoxia-Associated Proteins as Early Indicators of the Outcome in Patients with Metastatic Breast Cancer Given First-Line Bevacizumab-Based Therapy in another window
Includes: Supplementary data
Journal Articles

Clinical Effects of Adjuvant Active Specific Immunotherapy Differ between Patients with Microsatellite-Stable and Microsatellite-Instable Colon Cancer

Vincent A. de Weger, Annelies W. Turksma, Quirinus J.M. Voorham, Zelda Euler, Herman Bril, Alfons J. van den Eertwegh, Elisabeth Bloemena, Herbert M. Pinedo, Jan B. Vermorken, Harm van Tinteren, Gerrit A. Meijer, Erik Hooijberg
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (3): 882–889.
https://doi.org/10.1158/1078-0432.CCR-11-1716
Published: 31 January 2012
View article titled, Clinical Effects of Adjuvant Active Specific Immunotherapy Differ between Patients with Microsatellite-Stable and Microsatellite-Instable Colon Cancer
Open the PDF for Clinical Effects of Adjuvant Active Specific Immunotherapy Differ between Patients with Microsatellite-Stable and Microsatellite-Instable Colon Cancer in another window
Includes: Supplementary data
Journal Articles

On the Role of Melanoma-Specific CD8+ T-Cell Immunity in Disease Progression of Advanced-Stage Melanoma Patients

Monique van Oijen, Adriaan Bins, Sjoerd Elias, Johan Sein, Pauline Weder, Gijsbert de Gast, Henk Mallo, Maarten Gallee, Harm van Tinteren, Ton Schumacher, John Haanen
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (14): 4754–4760.
https://doi.org/10.1158/1078-0432.CCR-04-0260
Published: 21 July 2004
View article titled, On the Role of Melanoma-Specific CD8<sup>+</sup> T-Cell Immunity in Disease Progression of Advanced-Stage Melanoma Patients
Open the PDF for On the Role of Melanoma-Specific CD8<sup>+</sup> T-Cell Immunity in Disease Progression of Advanced-Stage Melanoma Patients in another window
Journal Articles

Predicting Early Failure after Adjuvant Chemotherapy in High-Risk Breast Cancer Patients with Extensive Lymph Node Involvement

Ian F. Faneyte, Johannes L. Peterse, Harm van Tinteren, Corina Pronk, Elisabeth G. E. de Vries, Sjoerd Rodenhuis, Marc J. van de Vijver
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (13): 4457–4463.
https://doi.org/10.1158/1078-0432.CCR-03-0054
Published: 06 July 2004
View article titled, Predicting Early Failure after Adjuvant Chemotherapy in High-Risk Breast Cancer Patients with Extensive Lymph Node Involvement
Open the PDF for Predicting Early Failure after Adjuvant Chemotherapy in High-Risk Breast Cancer Patients with Extensive Lymph Node Involvement in another window
Journal Articles

Expression of X-linked Inhibitor of Apoptosis as a Novel Prognostic Marker in Radically Resected Non-Small Cell Lung Cancer Patients

Carlos G. Ferreira, Paul van der Valk, Simone W. Span, Inge Ludwig, Egbert F. Smit, Frank A. E. Kruyt, Herbert M. Pinedo, Harm van Tinteren, Giuseppe Giaccone
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (8): 2468–2474.
Published: 01 August 2001
View article titled, Expression of X-linked Inhibitor of Apoptosis as a Novel Prognostic Marker in Radically Resected Non-Small Cell Lung Cancer Patients
Open the PDF for Expression of X-linked Inhibitor of Apoptosis as a Novel Prognostic Marker in Radically Resected Non-Small Cell Lung Cancer Patients in another window