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Journal Articles

Antitumor Activity of a Mitochondrial-Targeted HSP90 Inhibitor in Gliomas

Shiyou Wei, Delong Yin, Shengnan Yu, Xiang Lin, Milan R. Savani, Kuang Du, Yin Ku, Di Wu, Shasha Li, Hao Liu, Meng Tian, Yaohui Chen, Michelle Bowie, Seethalakshmi Hariharan, Matthew Waitkus, Stephen T. Keir, Eric T. Sugarman, Rebecca A. Deek, Marilyne Labrie, Mustafa Khasraw, Yiling Lu, Gordon B. Mills, Meenhard Herlyn, Kongming Wu, Lunxu Liu, Zhi Wei, Keith T. Flaherty, Kalil Abdullah, Gao Zhang, David M. Ashley
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (10): 2180–2195.
https://doi.org/10.1158/1078-0432.CCR-21-0833
Published: 13 May 2022
View article titled, Antitumor Activity of a Mitochondrial-Targeted HSP90 Inhibitor in Gliomas
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Includes: Supplementary data
Journal Articles

A Modified Nucleoside 6-Thio-2′-Deoxyguanosine Exhibits Antitumor Activity in Gliomas

Shengnan Yu, Shiyou Wei, Milan Savani, Xiang Lin, Kuang Du, Ilgen Mender, Silvia Siteni, Themistoklis Vasilopoulos, Zachary J. Reitman, Yin Ku, Di Wu, Hao Liu, Meng Tian, Yaohui Chen, Marilyne Labrie, Casey M. Charbonneau, Eric Sugarman, Michelle Bowie, Seethalakshmi Hariharan, Matthew Waitkus, Wen Jiang, Roger E. McLendon, Edward Pan, Mustafa Khasraw, Kyle M. Walsh, Yiling Lu, Meenhard Herlyn, Gordon Mills, Utz Herbig, Zhi Wei, Stephen T. Keir, Keith Flaherty, Lunxu Liu, Kongming Wu, Jerry W. Shay, Kalil Abdullah, Gao Zhang, David M. Ashley
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (24): 6800–6814.
https://doi.org/10.1158/1078-0432.CCR-21-0374
Published: 15 December 2021
View article titled, A Modified Nucleoside 6-Thio-2′-Deoxyguanosine Exhibits Antitumor Activity in Gliomas
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Includes: Supplementary data
Journal Articles

Abstract A06: Multiplatform analysis of early-stage cancer signatures in blood

Bingsi Li, Chenyang Wang, Jiayue Xu, Shuai Fang, Fujun Qiu, Jing Su, Huiling Chu, Han Han-Zhang, Xinru Mao, Hao Liu, Xianling Liu, Wei Zhang, Heng Zhao, Zhihong Zhang
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (11_Supplement): A06.
https://doi.org/10.1158/1557-3265.LiqBiop20-A06
Published: 01 June 2020
View article titled, Abstract A06: Multiplatform analysis of early-stage cancer signatures in blood
Journal Articles

T-Cell Receptor Stimulation Enhances the Expansion and Function of CD19 Chimeric Antigen Receptor–Expressing T Cells

Natalia Lapteva, Margaret Gilbert, Iulia Diaconu, Lisa A. Rollins, Mina Al-Sabbagh, Swati Naik, Robert A. Krance, Tamara Tripic, Manasa Hiregange, Darshana Raghavan, Olga Dakhova, Rayne H. Rouce, Hao Liu, Bilal Omer, Barbara Savoldo, Gianpietro Dotti, Conrad Russel Cruz, Keli Sharpe, Melissa Gates, Aaron Orozco, April Durett, Elizabeth Pacheco, Adrian P. Gee, Carlos A. Ramos, Helen E. Heslop, Malcolm K. Brenner, Cliona M. Rooney
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (24): 7340–7350.
https://doi.org/10.1158/1078-0432.CCR-18-3199
Published: 13 December 2019
View article titled, T-Cell Receptor Stimulation Enhances the Expansion and Function of CD19 Chimeric Antigen Receptor–Expressing T Cells
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Includes: Supplementary data
Journal Articles

Abstract A22: Establishing a deep cfDNA methylation sequencing-based signature for noninvasive early-stage lung cancer diagnosis

Zhihong Zhang, Naixin Liang, Wanglong Deng, Chenyang Wang, Tao Zheng, Wenjun Li, Jian Hu, Jinh Su, Han Han-Zhang, Bingsi Li, Hao Liu, Shanqing Li
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (17_Supplement): A22.
https://doi.org/10.1158/1557-3265.AACRIASLC18-A22
Published: 01 September 2018
View article titled, Abstract A22: Establishing a deep cfDNA methylation sequencing-based signature for noninvasive early-stage lung cancer diagnosis
Journal Articles

HSP27-Mediated Extracellular and Intracellular Signaling Pathways Synergistically Confer Chemoresistance in Squamous Cell Carcinoma of Tongue

Guopei Zheng, Zhijie Zhang, Hao Liu, Yan Xiong, Liyun Luo, Xiaoting Jia, Cong Peng, Qiong Zhang, Nan Li, Yixue Gu, Minying Lu, Ying Song, Hao Pan, Jinbao Liu, Wanqing Liu, Zhimin He
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (5): 1163–1175.
https://doi.org/10.1158/1078-0432.CCR-17-2619
Published: 28 February 2018
View article titled, HSP27-Mediated Extracellular and Intracellular Signaling Pathways Synergistically Confer Chemoresistance in Squamous Cell Carcinoma of Tongue
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Includes: Supplementary data
Journal Articles

A Radiomics Nomogram for the Preoperative Prediction of Lymph Node Metastasis in Bladder Cancer

Shaoxu Wu, Junjiong Zheng, Yong Li, Hao Yu, Siya Shi, Weibin Xie, Hao Liu, Yangfan Su, Jian Huang, Tianxin Lin
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (22): 6904–6911.
https://doi.org/10.1158/1078-0432.CCR-17-1510
Published: 14 November 2017
View article titled, A Radiomics Nomogram for the Preoperative Prediction of Lymph Node Metastasis in Bladder Cancer
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Includes: Supplementary data
Journal Articles

Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreatic Ductal Adenocarcinoma

Hao Liu, Kamila Naxerova, Matthias Pinter, Joao Incio, Hang Lee, Kohei Shigeta, William W. Ho, Jonathan A. Crain, Alex Jacobson, Theodoros Michelakos, Daniella Dias-Santos, Andrea Zanconato, Theodore S. Hong, Jeffrey W. Clark, Janet E. Murphy, David P. Ryan, Vikram Deshpande, Keith D. Lillemoe, Carlos Fernandez-del Castillo, Michael Downes, Ronald M. Evans, James Michaelson, Cristina R. Ferrone, Yves Boucher, Rakesh K. Jain
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (19): 5959–5969.
https://doi.org/10.1158/1078-0432.CCR-17-0256
Published: 01 October 2017
View article titled, Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreatic Ductal Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Interleukin-17–Producing Neutrophils Link Inflammatory Stimuli to Disease Progression by Promoting Angiogenesis in Gastric Cancer

Tuan-Jie Li, Yu-Ming Jiang, Yan-Feng Hu, Lei Huang, Jiang Yu, Li-Ying Zhao, Hai-Jun Deng, Ting-Yu Mou, Hao Liu, Yang Yang, Qi Zhang, Guo-Xin Li
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (6): 1575–1585.
https://doi.org/10.1158/1078-0432.CCR-16-0617
Published: 14 March 2017
View article titled, Interleukin-17–Producing Neutrophils Link Inflammatory Stimuli to Disease Progression by Promoting Angiogenesis in Gastric Cancer
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Includes: Supplementary data
Journal Articles

The use of glycan serum biomarkers for the detection of cancer

Suzanne Miyamoto, Hyun Joo An, Crystal Kirmiz, Bensheng Li, Caroline Chu, Hao Liu, Anthony Ferrige, Robert Alecio, Helen Chew, Gary Leiserowitz, Ralph deVere White, Kit S. Lam, Carlito B. Lebrilla
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (19_Supplement): A42.
Published: 15 August 2014
View article titled, The use of glycan serum biomarkers for the detection of cancer
Journal Articles

Metformin Sensitizes EGFR-TKI–Resistant Human Lung Cancer Cells In Vitro and In Vivo through Inhibition of IL-6 Signaling and EMT Reversal

Li Li, Rui Han, Hualiang Xiao, Caiyu Lin, Yubo Wang, Hao Liu, Kunlin Li, Hengyi Chen, Fenfen Sun, Zhenzhou Yang, Jianxin Jiang, Yong He
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (10): 2714–2726.
https://doi.org/10.1158/1078-0432.CCR-13-2613
Published: 14 May 2014
View article titled, Metformin Sensitizes EGFR-TKI–Resistant Human Lung Cancer Cells <em>In Vitro</em> and <em>In Vivo</em> through Inhibition of IL-6 Signaling and EMT Reversal
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Includes: Supplementary data
Journal Articles

Ultra Low-Dose IL-2 for GVHD Prophylaxis after Allogeneic Hematopoietic Stem Cell Transplantation Mediates Expansion of Regulatory T Cells without Diminishing Antiviral and Antileukemic Activity

Alana A. Kennedy-Nasser, Stephanie Ku, Paul Castillo-Caro, Yasmin Hazrat, Meng-Fen Wu, Hao Liu, Jos Melenhorst, A. John Barrett, Sawa Ito, Aaron Foster, Barbara Savoldo, Eric Yvon, George Carrum, Carlos A. Ramos, Robert A. Krance, Kathryn Leung, Helen E. Heslop, Malcolm K. Brenner, Catherine M. Bollard
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (8): 2215–2225.
https://doi.org/10.1158/1078-0432.CCR-13-3205
Published: 15 April 2014
View article titled, Ultra Low-Dose IL-2 for GVHD Prophylaxis after Allogeneic Hematopoietic Stem Cell Transplantation Mediates Expansion of Regulatory T Cells without Diminishing Antiviral and Antileukemic Activity
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Includes: Supplementary data
Journal Articles

Interleukin-7 Mediates Selective Expansion of Tumor-redirected Cytotoxic T Lymphocytes (CTLs) without Enhancement of Regulatory T-cell Inhibition

Serena K. Perna, Daria Pagliara, Aruna Mahendravada, Hao Liu, Malcolm K. Brenner, Barbara Savoldo, Gianpietro Dotti
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (1): 131–139.
https://doi.org/10.1158/1078-0432.CCR-13-1016
Published: 05 January 2014
View article titled, Interleukin-7 Mediates Selective Expansion of Tumor-redirected Cytotoxic T Lymphocytes (CTLs) without Enhancement of Regulatory T-cell Inhibition
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Includes: Supplementary data
Journal Articles

MEK-Independent Survival of B-RAFV600E Melanoma Cells Selected for Resistance to Apoptosis Induced by the RAF Inhibitor PLX4720

Chen Chen Jiang, Fritz Lai, Rick F. Thorne, Fan Yang, Hao Liu, Peter Hersey, Xu Dong Zhang
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (4): 721–730.
https://doi.org/10.1158/1078-0432.CCR-10-2225
Published: 15 February 2011
View article titled, MEK-Independent Survival of B-RAF<sup>V600E</sup> Melanoma Cells Selected for Resistance to Apoptosis Induced by the RAF Inhibitor PLX4720
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Journal Articles

Sorafenib Overcomes TRAIL Resistance of Hepatocellular Carcinoma Cells through the Inhibition of STAT3

Kuen-Feng Chen, Wei-Tien Tai, Tsung-Hao Liu, Hsiang-Po Huang, Yu-Chin Lin, Chung-Wai Shiau, Pui-Kai Li, Pei-Jer Chen, Ann-Lii Cheng
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (21): 5189–5199.
https://doi.org/10.1158/1078-0432.CCR-09-3389
Published: 31 October 2010
View article titled, Sorafenib Overcomes TRAIL Resistance of Hepatocellular Carcinoma Cells through the Inhibition of STAT3
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Journal Articles

GROα Is Highly Expressed in Adenocarcinoma of the Colon and Down-Regulates Fibulin-1

Yu Wen, Sarah F. Giardina, David Hamming, Jennifer Greenman, Emmanuel Zachariah, Manny D. Bacolod, Hao Liu, Jinru Shia, Peter S. Amenta, Francis Barany, Phillip Paty, William Gerald, Daniel Notterman
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (20): 5951–5959.
https://doi.org/10.1158/1078-0432.CCR-06-0736
Published: 24 October 2006
View article titled, GROα Is Highly Expressed in Adenocarcinoma of the Colon and Down-Regulates Fibulin-1
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Includes: Supplementary data
Journal Articles

Preclinical Pharmacologic Evaluation of MST-997, an Orally Active Taxane with Superior In vitro and In vivo Efficacy in Paclitaxel- and Docetaxel-Resistant Tumor Models

Deepak Sampath, Lee M. Greenberger, Carl Beyer, Malathi Hari, Hao Liu, Michelle Baxter, Sharon Yang, Carol Rios, Carolyn Discafani
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (11): 3459–3469.
https://doi.org/10.1158/1078-0432.CCR-05-2349
Published: 01 June 2006
View article titled, Preclinical Pharmacologic Evaluation of MST-997, an Orally Active Taxane with Superior <em>In vitro</em> and <em>In vivo</em> Efficacy in Paclitaxel- and Docetaxel-Resistant Tumor Models
Open the PDF for Preclinical Pharmacologic Evaluation of MST-997, an Orally Active Taxane with Superior <em>In vitro</em> and <em>In vivo</em> Efficacy in Paclitaxel- and Docetaxel-Resistant Tumor Models in another window