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Hans J. Hansen
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Journal Articles

CEACAM5-Targeted Therapy of Human Colonic and Pancreatic Cancer Xenografts with Potent Labetuzumab-SN-38 Immunoconjugates

Serengulam V. Govindan, Thomas M. Cardillo, Sung-Ju Moon, Hans J. Hansen, David M. Goldenberg
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (19): 6052–6061.
https://doi.org/10.1158/1078-0432.CCR-09-0586
Published: 30 September 2009
View article titled, CEACAM5-Targeted Therapy of Human Colonic and Pancreatic Cancer Xenografts with Potent Labetuzumab-SN-38 Immunoconjugates
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Journal Articles

CD74: A New Candidate Target for the Immunotherapy of B-Cell Neoplasms

Rhona Stein, M. Jules Mattes, Thomas M. Cardillo, Hans J. Hansen, Chien-Hsing Chang, Jack Burton, Serengulam Govindan, David M. Goldenberg
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (18): 5556s–5563s.
https://doi.org/10.1158/1078-0432.CCR-07-1167
Published: 17 September 2007
View article titled, CD74: A New Candidate Target for the Immunotherapy of B-Cell Neoplasms
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Journal Articles

Pretargeting of Carcinoembryonic Antigen–Expressing Cancers with a Trivalent Bispecific Fusion Protein Produced in Myeloma Cells

Edmund A. Rossi, Chien-Hsing Chang, Michele J. Losman, Robert M. Sharkey, Habibe Karacay, William McBride, Thomas M. Cardillo, Hans J. Hansen, Zhengxing Qu, Ivan D. Horak, David M. Goldenberg
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (19): 7122s–7129s.
https://doi.org/10.1158/1078-0432.CCR-1004-0020
Published: 03 October 2005
View article titled, Pretargeting of Carcinoembryonic Antigen–Expressing Cancers with a Trivalent Bispecific Fusion Protein Produced in Myeloma Cells
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Journal Articles

Anti-CD74 Antibody-Doxorubicin Conjugate, IMMU-110, in a Human Multiple Myeloma Xenograft and in Monkeys

Puja Sapra, Rhona Stein, Jennifer Pickett, Zhengxing Qu, Serengulam V. Govindan, Thomas M. Cardillo, Hans J. Hansen, Ivan D. Horak, Gary L. Griffiths, David M. Goldenberg
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (14): 5257–5264.
https://doi.org/10.1158/1078-0432.CCR-05-0204
Published: 20 July 2005
View article titled, Anti-CD74 Antibody-Doxorubicin Conjugate, IMMU-110, in a Human Multiple Myeloma Xenograft and in Monkeys
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Journal Articles

Advantage of a Residualizing Iodine Radiolabel in the Therapy of a Colon Cancer Xenograft Targeted with an Anticarcinoembryonic Antigen Monoclonal Antibody

Rhona Stein, Serengulam V. Govindan, Marianne Hayes, Gary L. Griffiths, Hans J. Hansen, Ivan D. Horak, David M. Goldenberg
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (7): 2727–2734.
https://doi.org/10.1158/1078-0432.CCR-04-2100
Published: 06 April 2005
View article titled, Advantage of a Residualizing Iodine Radiolabel in the Therapy of a Colon Cancer Xenograft Targeted with an Anticarcinoembryonic Antigen Monoclonal Antibody
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Journal Articles

Epratuzumab, a Humanized Anti-CD22 Antibody, in Aggressive Non-Hodgkin’s Lymphoma: Phase I/II Clinical Trial Results

John P. Leonard, Morton Coleman, Jamie C. Ketas, Amy Chadburn, Richard Furman, Michael W. Schuster, Eric J. Feldman, Michelle Ashe, Stephen J. Schuster, William A. Wegener, Hans J. Hansen, Heather Ziccardi, Michael Eschenberg, Urte Gayko, Scott Z. Fields, Alessandra Cesano, David M. Goldenberg
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (16): 5327–5334.
https://doi.org/10.1158/1078-0432.CCR-04-0294
Published: 24 August 2004
View article titled, Epratuzumab, a Humanized Anti-CD22 Antibody, in Aggressive Non-Hodgkin’s Lymphoma: <subtitle>Phase I/II Clinical Trial Results</subtitle>
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Journal Articles

Characterization of a New Humanized Anti-CD20 Monoclonal Antibody, IMMU-106, and Its Use in Combination with the Humanized Anti-CD22 Antibody, Epratuzumab, for the Therapy of Non-Hodgkin’s Lymphoma

Rhona Stein, Zhengxing Qu, Susan Chen, Adriane Rosario, Victoria Shi, Marianne Hayes, Ivan D. Horak, Hans J. Hansen, David M. Goldenberg
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (8): 2868–2878.
https://doi.org/10.1158/1078-0432.CCR-03-0493
Published: 20 April 2004
View article titled, Characterization of a New Humanized Anti-CD20 Monoclonal Antibody, IMMU-106, and Its Use in Combination with the Humanized Anti-CD22 Antibody, Epratuzumab, for the Therapy of Non-Hodgkin’s Lymphoma
Open the PDF for Characterization of a New Humanized Anti-CD20 Monoclonal Antibody, IMMU-106, and Its Use in Combination with the Humanized Anti-CD22 Antibody, Epratuzumab, for the Therapy of Non-Hodgkin’s Lymphoma in another window
Journal Articles

Cure of SCID Mice Bearing Human B-Lymphoma Xenografts by an Anti-CD74 Antibody-Anthracycline Drug Conjugate

Gary L. Griffiths, M. Jules Mattes, Rhona Stein, Serengulam V. Govindan, Ivan D. Horak, Hans J. Hansen, David M. Goldenberg
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (17): 6567–6571.
Published: 24 December 2003
View article titled, Cure of SCID Mice Bearing Human B-Lymphoma Xenografts by an Anti-CD74 Antibody-Anthracycline Drug Conjugate
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Journal Articles

Optimizing Bispecific Antibody Pretargeting for Use in Radioimmunotherapy

Robert M. Sharkey, Habibe Karacay, Heidi Richel, William J. McBride, Edmund A. Rossi, Ken Chang, Dion Yeldell, Gary L. Griffiths, Hans J. Hansen, David M. Goldenberg
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (10): 3897s–3913s.
Published: 01 September 2003
View article titled, Optimizing Bispecific Antibody Pretargeting for Use in Radioimmunotherapy
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Journal Articles

Development of New Multivalent-bispecific Agents for Pretargeting Tumor Localization and Therapy

Edmund A. Rossi, Robert M. Sharkey, William McBride, Habibe Karacay, Li Zeng, Hans J. Hansen, David M. Goldenberg, Chien-Hsing Chang
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (10): 3886s–3896s.
Published: 01 September 2003
View article titled, Development of New Multivalent-bispecific Agents for Pretargeting Tumor Localization and Therapy
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Journal Articles

The Effects of Domain Deletion, Glycosylation, and Long IgG3 Hinge on the Biodistribution and Serum Stability Properties of a Humanized IgG1 Immunoglobulin, hLL2, and Its Fragments

Shui-on Leung, Zhengxing Qu, Hans J. Hansen, Lisa B. Shih, Jingrong Wang, Michele J. Losman, David M. Goldenberg, Robert M. Sharkey
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (10): 3106s–3117s.
Published: 01 October 1999
View article titled, The Effects of Domain Deletion, Glycosylation, and Long IgG<sub>3</sub> Hinge on the Biodistribution and Serum Stability Properties of a Humanized IgG<sub>1</sub> Immunoglobulin, hLL2, and Its Fragments
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Journal Articles

Generation and Monitoring of Cell Lines Producing Humanized Antibodies

Michele J. Losman, Zhengxing Qu, Indira S. Krishnan, Jingrong Wang, Hans J. Hansen, David M. Goldenberg, Shui-on Leung
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (10): 3101s–3105s.
Published: 01 October 1999
View article titled, Generation and Monitoring of Cell Lines Producing Humanized Antibodies
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Journal Articles

Humanization of Immu31, an α-Fetoprotein-specific Antibody

Zhengxing Qu, Michele J. Losman, Kristian C. Eliassen, Hans J. Hansen, David M. Goldenberg, Shui-on Leung
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (10): 3095s–3100s.
Published: 01 October 1999
View article titled, Humanization of Immu31, an α-Fetoprotein-specific Antibody
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Journal Articles

Targeting Human Cancer Xenografts with Monoclonal Antibodies Labeled Using Radioiodinated, Diethylenetriaminepentaacetic Acid-appended Peptides

Rhona Stein, Serengulam V. Govindan, M. Jules Mattes, Lisa B. Shih, Gary L. Griffiths, Hans J. Hansen, David M. Goldenberg
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (10): 3079s–3087s.
Published: 01 October 1999
View article titled, Targeting Human Cancer Xenografts with Monoclonal Antibodies Labeled Using Radioiodinated, Diethylenetriaminepentaacetic Acid-appended Peptides
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Journal Articles

Radiolabeling of an Anti-Carcinoembryonic Antigen Antibody Fab′ Fragment (CEA-Scan) with the Positron-emitting Radionuclide Tc-94m

Gary L. Griffiths, David M. Goldenberg, Frank Roesch, Hans J. Hansen
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (10): 3001s–3003s.
Published: 01 October 1999
View article titled, Radiolabeling of an Anti-Carcinoembryonic Antigen Antibody Fab′ Fragment (CEA-Scan) with the Positron-emitting Radionuclide Tc-94m
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