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Journal Articles

First-in-Class, First-in-Human Study Evaluating LV305, a Dendritic-Cell Tropic Lentiviral Vector, in Sarcoma and Other Solid Tumors Expressing NY-ESO-1

Neeta Somaiah, Matthew S. Block, Joseph W. Kim, Geoffrey I. Shapiro, Khanh T. Do, Patrick Hwu, Joseph P. Eder, Robin L. Jones, Hailing Lu, Jan H. ter Meulen, Chet Bohac, Michael Chen, Frank J. Hsu, Sacha Gnjatic, Seth M. Pollack
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (19): 5808–5817.
https://doi.org/10.1158/1078-0432.CCR-19-1025
Published: 01 October 2019
View article titled, First-in-Class, First-in-Human Study Evaluating LV305, a Dendritic-Cell Tropic Lentiviral Vector, in Sarcoma and Other Solid Tumors Expressing NY-ESO-1
Open the PDF for First-in-Class, First-in-Human Study Evaluating LV305, a Dendritic-Cell Tropic Lentiviral Vector, in Sarcoma and Other Solid Tumors Expressing NY-ESO-1 in another window
Includes: Supplementary data
Journal Articles

Intratumoral G100, a TLR4 Agonist, Induces Antitumor Immune Responses and Tumor Regression in Patients with Merkel Cell Carcinoma

Shailender Bhatia, Natalie J. Miller, Hailing Lu, Natalie V. Longino, Dafina Ibrani, Michi M. Shinohara, David R. Byrd, Upendra Parvathaneni, Rima Kulikauskas, Jan ter Meulen, Frank J. Hsu, David M. Koelle, Paul Nghiem
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (4): 1185–1195.
https://doi.org/10.1158/1078-0432.CCR-18-0469
Published: 15 February 2019
View article titled, Intratumoral G100, a TLR4 Agonist, Induces Antitumor Immune Responses and Tumor Regression in Patients with Merkel Cell Carcinoma
Open the PDF for Intratumoral G100, a TLR4 Agonist, Induces Antitumor Immune Responses and Tumor Regression in Patients with Merkel Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

VTX-2337 Is a Novel TLR8 Agonist That Activates NK Cells and Augments ADCC

Hailing Lu, Gregory N. Dietsch, Maura-Ann H. Matthews, Yi Yang, Smita Ghanekar, Margaret Inokuma, Maria Suni, Vernon C. Maino, Katherine E. Henderson, James Jeffry Howbert, Mary L. Disis, Robert M. Hershberg
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (2): 499–509.
https://doi.org/10.1158/1078-0432.CCR-11-1625
Published: 16 January 2012
View article titled, VTX-2337 Is a Novel TLR8 Agonist That Activates NK Cells and Augments ADCC
Open the PDF for VTX-2337 Is a Novel TLR8 Agonist That Activates NK Cells and Augments ADCC in another window
Includes: Supplementary data
Journal Articles

TLR2 Agonist PSK Activates Human NK Cells and Enhances the Antitumor Effect of HER2-Targeted Monoclonal Antibody Therapy

Hailing Lu, Yi Yang, Ekram Gad, Carol Inatsuka, Cynthia A. Wenner, Mary L. Disis, Leanna J. Standish
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (21): 6742–6753.
https://doi.org/10.1158/1078-0432.CCR-11-1142
Published: 31 October 2011
View article titled, TLR2 Agonist PSK Activates Human NK Cells and Enhances the Antitumor Effect of HER2-Targeted Monoclonal Antibody Therapy
Open the PDF for TLR2 Agonist PSK Activates Human NK Cells and Enhances the Antitumor Effect of HER2-Targeted Monoclonal Antibody Therapy in another window
Includes: Supplementary data
Journal Articles

Polysaccharide Krestin Is a Novel TLR2 Agonist that Mediates Inhibition of Tumor Growth via Stimulation of CD8 T Cells and NK Cells

Hailing Lu, Yi Yang, Ekram Gad, Cynthia A. Wenner, Amy Chang, Emily R. Larson, Yushe Dang, Mark Martzen, Leanna J. Standish, Mary L. Disis
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (1): 67–76.
https://doi.org/10.1158/1078-0432.CCR-10-1763
Published: 04 January 2011
View article titled, Polysaccharide Krestin Is a Novel TLR2 Agonist that Mediates Inhibition of Tumor Growth via Stimulation of CD8 T Cells and NK Cells
Open the PDF for Polysaccharide Krestin Is a Novel TLR2 Agonist that Mediates Inhibition of Tumor Growth via Stimulation of CD8 T Cells and NK Cells in another window
Includes: Supplementary data