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Gudrun Schleiermacher
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Journal Articles

Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving ALK-Targeted Therapy

Open Access
Charles Bobin, Yasmine Iddir, Charlotte Butterworth, Julien Masliah-Planchon, Alexandra Saint-Charles, Angela Bellini, Jaydutt Bhalshankar, Gaelle Pierron, Valérie Combaret, Valéry Attignon, Nicolas André, Nadège Corradini, Benoit Dumont, Ludovic Mansuy, Camille Khanfar, Sebastien Klein, Claire Briandet, Dominique Plantaz, Frederic Millot, Sandrine Thouvenin, Isabelle Aerts, Lee Aymar Ndounga-Diakou, Salim Laghouati, Samuel Abbou, Nina Jehanno, Hubert Tissot, Shufang Renault, Sylvain Baulande, Virginie Raynal, Laurence Bozec, Ivan Bieche, Olivier Delattre, Pablo Berlanga, Gudrun Schleiermacher
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (15): 3316–3328.
https://doi.org/10.1158/1078-0432.CCR-24-0753
Published: 01 August 2024
View article titled, Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving ALK-Targeted Therapy
Open the PDF for Sequential Analysis of cfDNA Reveals Clonal Evolution in Patients with Neuroblastoma Receiving ALK-Targeted Therapy in another window
Includes: Supplementary data
Journal Articles

Combination Therapies Targeting ALK-aberrant Neuroblastoma in Preclinical Models

Open Access
Elizabeth R. Tucker, Irene Jiménez, Lindi Chen, Angela Bellini, Chiara Gorrini, Elizabeth Calton, Qiong Gao, Harvey Che, Evon Poon, Yann Jamin, Barbara Martins Da Costa, Karen Barker, Sumana Shrestha, J. Ciaran Hutchinson, Simran Dhariwal, Angharad Goodman, Elaine Del Nery, Pierre Gestraud, Jaydutt Bhalshankar, Yasmine Iddir, Elnaz Saberi-Ansari, Alexandra Saint-Charles, Birgit Geoerger, Maria Eugénia Marques Da Costa, Cécile Pierre-Eugène, Isabelle Janoueix-Lerosey, Didier Decaudin, Fariba Nemati, Angel M. Carcaboso, Didier Surdez, Olivier Delattre, Sally L. George, Louis Chesler, Deborah A. Tweddle, Gudrun Schleiermacher
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (7): 1317–1331.
https://doi.org/10.1158/1078-0432.CCR-22-2274
Published: 03 April 2023
View article titled, Combination Therapies Targeting ALK-aberrant Neuroblastoma in Preclinical Models
Open the PDF for Combination Therapies Targeting ALK-aberrant Neuroblastoma in Preclinical Models in another window
Includes: Supplementary data
Journal Articles

Abstract B48: Minimally invasive classification of pediatric solid tumors using reduced representation bisulfite sequencing of cell-free DNA

Free
Ruben Van Paemel, Andries De Koker, Charlotte Vandeputte, Lieke Van Zogchel, Tim Lammens, Geneviève Laureys, Jo Vandesompele, Gudrun Schleiermacher, Matthieu Chicard, Nadine Van Roy, Ales Vicha, Godelieve A. M. Tytgat, Nico Callewaert, Bram De Wilde, Katleen De Preter
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (11_Supplement): B48.
https://doi.org/10.1158/1557-3265.LiqBiop20-B48
Published: 01 June 2020
View article titled, Abstract B48: Minimally invasive classification of pediatric solid tumors using reduced representation bisulfite sequencing of cell-free DNA
Journal Articles

Whole-Exome Sequencing of Cell-Free DNA Reveals Temporo-spatial Heterogeneity and Identifies Treatment-Resistant Clones in Neuroblastoma

Free
Mathieu Chicard, Leo Colmet-Daage, Nathalie Clement, Adrien Danzon, Mylène Bohec, Virginie Bernard, Sylvain Baulande, Angela Bellini, Paul Deveau, Gaëlle Pierron, Eve Lapouble, Isabelle Janoueix-Lerosey, Michel Peuchmaur, Nadège Corradini, Anne Sophie Defachelles, Dominique Valteau-Couanet, Jean Michon, Valérie Combaret, Olivier Delattre, Gudrun Schleiermacher
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (4): 939–949.
https://doi.org/10.1158/1078-0432.CCR-17-1586
Published: 14 February 2018
View article titled, Whole-Exome Sequencing of Cell-Free DNA Reveals Temporo-spatial Heterogeneity and Identifies Treatment-Resistant Clones in Neuroblastoma
Open the PDF for Whole-Exome Sequencing of Cell-Free DNA Reveals Temporo-spatial Heterogeneity and Identifies Treatment-Resistant Clones in Neuroblastoma in another window
Includes: Supplementary data
Journal Articles

Genomic Copy Number Profiling Using Circulating Free Tumor DNA Highlights Heterogeneity in Neuroblastoma

Free
Mathieu Chicard, Sandrine Boyault, Leo Colmet Daage, Wilfrid Richer, David Gentien, Gaelle Pierron, Eve Lapouble, Angela Bellini, Nathalie Clement, Isabelle Iacono, Stéphanie Bréjon, Marjorie Carrere, Cécile Reyes, Toby Hocking, Virginie Bernard, Michel Peuchmaur, Nadège Corradini, Cécile Faure-Conter, Carole Coze, Dominique Plantaz, Anne Sophie Defachelles, Estelle Thebaud, Marion Gambart, Frédéric Millot, Dominique Valteau-Couanet, Jean Michon, Alain Puisieux, Olivier Delattre, Valérie Combaret, Gudrun Schleiermacher
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2016) 22 (22): 5564–5573.
https://doi.org/10.1158/1078-0432.CCR-16-0500
Published: 14 November 2016
View article titled, Genomic Copy Number Profiling Using Circulating Free Tumor DNA Highlights Heterogeneity in Neuroblastoma
Open the PDF for Genomic Copy Number Profiling Using Circulating Free Tumor DNA Highlights Heterogeneity in Neuroblastoma in another window
Includes: Supplementary data
Journal Articles

Deep Sequencing Reveals Occurrence of Subclonal ALK Mutations in Neuroblastoma at Diagnosis

Free
Angela Bellini, Virginie Bernard, Quentin Leroy, Thomas Rio Frio, Gaelle Pierron, Valérie Combaret, Eve Lapouble, Nathalie Clement, Herve Rubie, Estelle Thebaud, Pascal Chastagner, Anne Sophie Defachelles, Christophe Bergeron, Nimrod Buchbinder, Sophie Taque, Anne Auvrignon, Dominique Valteau-Couanet, Jean Michon, Isabelle Janoueix-Lerosey, Olivier Delattre, Gudrun Schleiermacher
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2015) 21 (21): 4913–4921.
https://doi.org/10.1158/1078-0432.CCR-15-0423
Published: 01 November 2015
View article titled, Deep Sequencing Reveals Occurrence of Subclonal ALK Mutations in Neuroblastoma at Diagnosis
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Includes: Supplementary data
Journal Articles

Revised Risk Estimation and Treatment Stratification of Low- and Intermediate-Risk Neuroblastoma Patients by Integrating Clinical and Molecular Prognostic Markers

Free
André Oberthuer, Dilafruz Juraeva, Barbara Hero, Ruth Volland, Carolina Sterz, Rene Schmidt, Andreas Faldum, Yvonne Kahlert, Anne Engesser, Shahab Asgharzadeh, Robert Seeger, Miki Ohira, Akira Nakagawara, Paola Scaruffi, Gian Paolo Tonini, Isabelle Janoueix-Lerosey, Olivier Delattre, Gudrun Schleiermacher, Jo Vandesompele, Frank Speleman, Rosa Noguera, Marta Piqueras, Jean Bénard, Alexander Valent, Smadar Avigad, Isaac Yaniv, Richard G. Grundy, Monika Ortmann, Chunxuan Shao, Manfred Schwab, Roland Eils, Thorsten Simon, Jessica Theissen, Frank Berthold, Frank Westermann, Benedikt Brors, Matthias Fischer
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (8): 1904–1915.
https://doi.org/10.1158/1078-0432.CCR-14-0817
Published: 14 April 2015
View article titled, Revised Risk Estimation and Treatment Stratification of Low- and Intermediate-Risk Neuroblastoma Patients by Integrating Clinical and Molecular Prognostic Markers
Open the PDF for Revised Risk Estimation and Treatment Stratification of Low- and Intermediate-Risk Neuroblastoma Patients by Integrating Clinical and Molecular Prognostic Markers in another window
Includes: Supplementary data
Journal Articles

A Multilocus Technique for Risk Evaluation of Patients with Neuroblastoma

Free
Inge M. Ambros, Bettina Brunner, Gerhard Aigner, Clare Bedwell, Klaus Beiske, Jean Bénard, Nick Bown, Valerie Combaret, Jerome Couturier, Raffaella Defferrari, Nicole Gross, Marta Jeison, John Lunec, Barbara Marques, Tommy Martinsson, Katia Mazzocco, Rosa Noguera, Gudrun Schleiermacher, Frank Speleman, Ray Stallings, Gian Paolo Tonini, Deborah A. Tweddle, Alexander Valent, Ales Vicha, Nadine Van Roy, Eva Villamon, Andrea Ziegler, Sandra Preuner, Mario Drobics, Ruth Ladenstein, Gabriele Amann, Robert J.L. Schuit, Ulrike Pötschger, Peter F. Ambros
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (4): 792–804.
https://doi.org/10.1158/1078-0432.CCR-10-0830
Published: 15 February 2011
View article titled, A Multilocus Technique for Risk Evaluation of Patients with Neuroblastoma
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Journal Articles

Accurate Outcome Prediction in Neuroblastoma across Independent Data Sets Using a Multigene Signature

Free
Katleen De Preter, Joëlle Vermeulen, Benedikt Brors, Olivier Delattre, Angelika Eggert, Matthias Fischer, Isabelle Janoueix-Lerosey, Cinzia Lavarino, John M. Maris, Jaume Mora, Akira Nakagawara, André Oberthuer, Miki Ohira, Gudrun Schleiermacher, Alexander Schramm, Johannes H. Schulte, Qun Wang, Frank Westermann, Frank Speleman, Jo Vandesompele
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (5): 1532–1541.
https://doi.org/10.1158/1078-0432.CCR-09-2607
Published: 28 February 2010
View article titled, Accurate Outcome Prediction in Neuroblastoma across Independent Data Sets Using a Multigene Signature
Open the PDF for Accurate Outcome Prediction in Neuroblastoma across Independent Data Sets Using a Multigene Signature in another window
Includes: Supplementary data