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Journal Articles

ATR Inhibition Induces CDK1–SPOP Signaling and Enhances Anti–PD-L1 Cytotoxicity in Prostate Cancer

Zhe Tang, Patrick G. Pilié, Chuandong Geng, Ganiraju C. Manyam, Guang Yang, Sanghee Park, Daoqi Wang, Shan Peng, Cheng Wu, Guang Peng, Timothy A. Yap, Paul G. Corn, Bradley M. Broom, Timothy C. Thompson
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (17): 4898–4909.
https://doi.org/10.1158/1078-0432.CCR-21-1010
Published: 01 September 2021
View article titled, ATR Inhibition Induces CDK1–SPOP Signaling and Enhances Anti–PD-L1 Cytotoxicity in Prostate Cancer
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Includes: Supplementary data
Journal Articles

PARP Inhibition Suppresses GR–MYCN–CDK5–RB1–E2F1 Signaling and Neuroendocrine Differentiation in Castration-Resistant Prostate Cancer

Bo Liu, Likun Li, Guang Yang, Chuandong Geng, Yong Luo, Wenhui Wu, Ganiraju C. Manyam, Dimitrios Korentzelos, Sanghee Park, Zhe Tang, Cheng Wu, Zhenyang Dong, Michael Sigouros, Andrea Sboner, Himisha Beltran, Yu Chen, Paul G. Corn, Michael T. Tetzlaff, Patricia Troncoso, Bradley Broom, Timothy C. Thompson
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (22): 6839–6851.
https://doi.org/10.1158/1078-0432.CCR-19-0317
Published: 15 November 2019
View article titled, PARP Inhibition Suppresses GR–MYCN–CDK5–RB1–E2F1 Signaling and Neuroendocrine Differentiation in Castration-Resistant Prostate Cancer
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Includes: Supplementary data
Journal Articles

Prospective Clinical Trial of Ixazomib, Dexamethasone, and Rituximab as Primary Therapy in Waldenström Macroglobulinemia

Jorge J. Castillo, Kirsten Meid, Joshua N. Gustine, Toni Dubeau, Patricia Severns, Zachary R. Hunter, Guang Yang, Lian Xu, Steven P. Treon
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (14): 3247–3252.
https://doi.org/10.1158/1078-0432.CCR-18-0152
Published: 15 July 2018
View article titled, Prospective Clinical Trial of Ixazomib, Dexamethasone, and Rituximab as Primary Therapy in Waldenström Macroglobulinemia
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Journal Articles

Targeting the MYCN–PARP–DNA Damage Response Pathway in Neuroendocrine Prostate Cancer

Wei Zhang, Bo Liu, Wenhui Wu, Likun Li, Bradley M. Broom, Spyridon P. Basourakos, Dimitrios Korentzelos, Yang Luan, Jianxiang Wang, Guang Yang, Sanghee Park, Abul Kalam Azad, Xuhong Cao, Jeri Kim, Paul G. Corn, Christopher J. Logothetis, Ana M. Aparicio, Arul M. Chinnaiyan, Nora Navone, Patricia Troncoso, Timothy C. Thompson
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (3): 696–707.
https://doi.org/10.1158/1078-0432.CCR-17-1872
Published: 31 January 2018
View article titled, Targeting the MYCN–PARP–DNA Damage Response Pathway in Neuroendocrine Prostate Cancer
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Includes: Supplementary data
Journal Articles

Prospective, Multicenter Clinical Trial of Everolimus as Primary Therapy in Waldenstrom Macroglobulinemia (WMCTG 09-214)

Steven P. Treon, Kirsten Meid, Christina Tripsas, Leonard T. Heffner, Herbert Eradat, Ashraf Z. Badros, Lian Xu, Zachary R. Hunter, Guang Yang, Christopher J. Patterson, Joshua Gustine, Jorge J. Castillo, Jeffrey Matous, Irene M. Ghobrial
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (10): 2400–2404.
https://doi.org/10.1158/1078-0432.CCR-16-1918
Published: 14 May 2017
View article titled, Prospective, Multicenter Clinical Trial of Everolimus as Primary Therapy in Waldenstrom Macroglobulinemia (WMCTG 09-214)
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Journal Articles

Targeting the Spleen Tyrosine Kinase with Fostamatinib as a Strategy against Waldenström Macroglobulinemia

Isere Kuiatse, Veerabhadran Baladandayuthapani, Heather Y. Lin, Sheeba K. Thomas, Chad C. Bjorklund, Donna M. Weber, Michael Wang, Jatin J. Shah, Xing-Ding Zhang, Richard J. Jones, Stephen M. Ansell, Guang Yang, Steven P. Treon, Robert Z. Orlowski
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (11): 2538–2545.
https://doi.org/10.1158/1078-0432.CCR-14-1462
Published: 31 May 2015
View article titled, Targeting the Spleen Tyrosine Kinase with Fostamatinib as a Strategy against Waldenström Macroglobulinemia
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Includes: Supplementary data
Journal Articles

Aberrant Splicing of Hugl-1 Is Associated with Hepatocellular Carcinoma Progression

Xuefeng Lu, Xiujing Feng, Xiaobo Man, Guang Yang, Liang Tang, Dan Du, Fan Zhang, Haixin Yuan, Qin Huang, Zhe Zhang, Yinkun Liu, Dennis Strand, Zhengjun Chen
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (10): 3287–3296.
https://doi.org/10.1158/1078-0432.CCR-08-2078
Published: 18 May 2009
View article titled, Aberrant Splicing of <em>Hugl-1</em> Is Associated with Hepatocellular Carcinoma Progression
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Includes: Supplementary data
Journal Articles

High Levels of Phosphorylated Form of Akt-1 in Prostate Cancer and Non-Neoplastic Prostate Tissues Are Strong Predictors of Biochemical Recurrence

Gustavo Ayala, Timothy Thompson, Guang Yang, Anna Frolov, Rile Li, Peter Scardino, Makoto Ohori, Thomas Wheeler, Wade Harper
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (19): 6572–6578.
https://doi.org/10.1158/1078-0432.CCR-04-0477
Published: 08 October 2004
View article titled, High Levels of Phosphorylated Form of Akt-1 in Prostate Cancer and Non-Neoplastic Prostate Tissues Are Strong Predictors of Biochemical Recurrence
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Journal Articles

Elevated Skp2 Protein Expression in Human Prostate Cancer: Association with Loss of the Cyclin-dependent Kinase Inhibitor p27 and PTEN and with Reduced Recurrence-free Survival

Guang Yang, Gustavo Ayala, Angelo De Marzo, Weihua Tian, Anna Frolov, Thomas M. Wheeler, Timothy C. Thompson, J. Wade Harper
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (11): 3419–3426.
Published: 01 November 2002
View article titled, Elevated Skp2 Protein Expression in Human Prostate Cancer: <subtitle>Association with Loss of the Cyclin-dependent Kinase Inhibitor p27 and PTEN and with Reduced Recurrence-free Survival</subtitle>
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Journal Articles

In Situ Prostate Cancer Gene Therapy Using a Novel Adenoviral Vector Regulated by the Caveolin-1 Promoter

Christina Pramudji, Satoru Shimura, Shin Ebara, Guang Yang, Jianxiang Wang, Chengzhen Ren, Yunfei Yuan, Salahaldin A. Tahir, Terry L. Timme, Timothy C. Thompson
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (12): 4272–4279.
Published: 01 December 2001
View article titled, <em>In Situ</em> Prostate Cancer Gene Therapy Using a Novel Adenoviral Vector Regulated by the Caveolin-1 Promoter
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Journal Articles

Prostate Cancer Gene Therapy: Comparison of Adenovirus-mediated Expression of Interleukin 12 with Interleukin 12 plus B7-1 for in Situ Gene Therapy and Gene-modified, Cell-based Vaccines

Gerald W. Hull, Mark A. McCurdy, Yasutomo Nasu, Chris H. Bangma, Guang Yang, Satoru Shimura, Hon-Man Lee, Jianxiang Wang, Justin Albani, Shin Ebara, Takefumi Sato, Terry L. Timme, Timothy C. Thompson
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (10): 4101–4109.
Published: 01 October 2000
View article titled, Prostate Cancer Gene Therapy: Comparison of Adenovirus-mediated Expression of Interleukin 12 with Interleukin 12 plus B7-1 for <em>in Situ</em> Gene Therapy and Gene-modified, Cell-based Vaccines
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Journal Articles

Elevated Caveolin-1 Levels in African-American versus White-American Prostate Cancer

Guang Yang, Josephine Addai, Michael Ittmann, Thomas M. Wheeler, Timothy C. Thompson
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (9): 3430–3433.
Published: 01 September 2000
View article titled, Elevated Caveolin-1 Levels in African-American <em>versus</em> White-American Prostate Cancer
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