1-20 of 44
Gregory J. Riely
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Clinical and Molecular Features of Long-term Response to Immune Checkpoint Inhibitors in Patients with Advanced Non–Small Cell Lung Cancer

Rohit Thummalapalli, Biagio Ricciuti, Chaitanya Bandlamudi, Daniel Muldoon, Hira Rizvi, Arielle Elkrief, Jia Luo, Joao V. Alessi, Federica Pecci, Giuseppe Lamberti, Alessandro Di Federico, Lingzhi Hong, Jianjun Zhang, John V. Heymach, Don L. Gibbons, Andrew J. Plodkowski, Vignesh Ravichandran, Mark T.A. Donoghue, Chad Vanderbilt, Marc Ladanyi, Charles M. Rudin, Mark G. Kris, Gregory J. Riely, Jamie E. Chaft, Matthew D. Hellmann, Natalie I. Vokes, Mark M. Awad, Adam J. Schoenfeld
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (21): 4408–4418.
https://doi.org/10.1158/1078-0432.CCR-23-1207
Published: 01 November 2023
View article titled, Clinical and Molecular Features of Long-term Response to Immune Checkpoint Inhibitors in Patients with Advanced Non–Small Cell Lung Cancer
Open the PDF for Clinical and Molecular Features of Long-term Response to Immune Checkpoint Inhibitors in Patients with Advanced Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

The GENIE BPC NSCLC Cohort: A Real-World Repository Integrating Standardized Clinical and Genomic Data for 1,846 Patients with Non–Small Cell Lung Cancer

Noura J. Choudhury, Jessica A. Lavery, Samantha Brown, Ino de Bruijn, Justin Jee, Thinh Ngoc Tran, Hira Rizvi, Kathryn C. Arbour, Karissa Whiting, Ronglai Shen, Matthew Hellmann, Philippe L. Bedard, Celeste Yu, Natasha Leighl, Michele LeNoue-Newton, Christine Micheel, Jeremy L. Warner, Michelle S. Ginsberg, Andrew Plodkowski, Jeffrey Girshman, Peter Sawan, Shirin Pillai, Shawn M. Sweeney, Kenneth L. Kehl, Katherine S. Panageas, Nikolaus Schultz, Deborah Schrag, Gregory J. Riely, on behalf of the AACR GENIE BPC Core Team
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (17): 3418–3428.
https://doi.org/10.1158/1078-0432.CCR-23-0580
Published: 01 September 2023
View article titled, The GENIE BPC NSCLC Cohort: A Real-World Repository Integrating Standardized Clinical and Genomic Data for 1,846 Patients with Non–Small Cell Lung Cancer
Open the PDF for The GENIE BPC NSCLC Cohort: A Real-World Repository Integrating Standardized Clinical and Genomic Data for 1,846 Patients with Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Early Changes in Circulating Cell-Free KRAS G12C Predict Response to Adagrasib in KRAS Mutant Non–Small Cell Lung Cancer Patients

Cloud P. Paweletz, Grace A. Heavey, Yanan Kuang, Emily Durlacher, Thian Kheoh, Richard C. Chao, Alexander I. Spira, Konstantinos Leventakos, Melissa L. Johnson, Sai-Hong Ignatius Ou, Gregory J. Riely, Kenna Anderes, Wenjing Yang, James G. Christensen, Pasi A. Jänne
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (16): 3074–3080.
https://doi.org/10.1158/1078-0432.CCR-23-0795
Published: 15 August 2023
View article titled, Early Changes in Circulating Cell-Free <em>KRAS</em> G12C Predict Response to Adagrasib in KRAS Mutant Non–Small Cell Lung Cancer Patients
Open the PDF for Early Changes in Circulating Cell-Free <em>KRAS</em> G12C Predict Response to Adagrasib in KRAS Mutant Non–Small Cell Lung Cancer Patients in another window
Includes: Supplementary data
Journal Articles

Brief Report: Combination of Osimertinib and Dacomitinib to Mitigate Primary and Acquired Resistance in EGFR-Mutant Lung Adenocarcinomas

Arielle Elkrief, Alex Makhnin, Khadeja A. Moses, Linda S. Ahn, Isabel R. Preeshagul, Afsheen N. Iqbal, Sara A. Hayes, Andrew J. Plodkowski, Paul K. Paik, Marc Ladanyi, Mark G. Kris, Gregory J. Riely, Franziska Michor, Helena A. Yu
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (8): 1423–1428.
https://doi.org/10.1158/1078-0432.CCR-22-3484
Published: 14 April 2023
View article titled, Brief Report: Combination of Osimertinib and Dacomitinib to Mitigate Primary and Acquired Resistance in <em>EGFR</em>-Mutant Lung Adenocarcinomas
Open the PDF for Brief Report: Combination of Osimertinib and Dacomitinib to Mitigate Primary and Acquired Resistance in <em>EGFR</em>-Mutant Lung Adenocarcinomas in another window
Includes: Supplementary data
Journal Articles

Systemic and Oligo-Acquired Resistance to PD-(L)1 Blockade in Lung Cancer

Adam J. Schoenfeld, Hira A. Rizvi, Danish Memon, Narek Shaverdian, Matthew J. Bott, Jennifer L. Sauter, C. Jillian Tsai, Jayon Lihm, David Hoyos, Andrew J. Plodkowski, Rocio Perez-Johnston, Peter Sawan, Jacklynn V. Egger, Benjamin D. Greenbaum, Andreas Rimner, Gregory J. Riely, Charles M. Rudin, Valerie W. Rusch, Daniel R. Gomez, Matthew D. Hellmann
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (17): 3797–3803.
https://doi.org/10.1158/1078-0432.CCR-22-0657
Published: 01 September 2022
View article titled, Systemic and Oligo-Acquired Resistance to PD-(L)1 Blockade in Lung Cancer
Open the PDF for Systemic and Oligo-Acquired Resistance to PD-(L)1 Blockade in Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Replication of Overall Survival, Progression-Free Survival, and Overall Response in Chemotherapy Arms of Non–Small Cell Lung Cancer Trials Using Real-World Data

Thanh G.N. Ton, Navdeep Pal, Huong Trinh, Sami Mahrus, Michael T. Bretscher, Robson J.M. Machado, Natalia Sadetsky, Nayan Chaudhary, Michael W. Lu, Gregory J. Riely
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (13): 2844–2853.
https://doi.org/10.1158/1078-0432.CCR-22-0471
Published: 01 July 2022
View article titled, Replication of Overall Survival, Progression-Free Survival, and Overall Response in Chemotherapy Arms of Non–Small Cell Lung Cancer Trials Using Real-World Data
Open the PDF for Replication of Overall Survival, Progression-Free Survival, and Overall Response in Chemotherapy Arms of Non–Small Cell Lung Cancer Trials Using Real-World Data in another window
Includes: Supplementary data
Journal Articles

Response to Standard Therapies and Comprehensive Genomic Analysis for Patients with Lung Adenocarcinoma with EGFR Exon 20 Insertions

Noura J. Choudhury, Adam J. Schoenfeld, Jessica Flynn, Christina J. Falcon, Hira Rizvi, Charles M. Rudin, Mark G. Kris, Maria E. Arcila, Glenn Heller, Helena A. Yu, Marc Ladanyi, Gregory J. Riely
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2021) 27 (10): 2920–2927.
https://doi.org/10.1158/1078-0432.CCR-20-4650
Published: 15 May 2021
View article titled, Response to Standard Therapies and Comprehensive Genomic Analysis for Patients with Lung Adenocarcinoma with <em>EGFR</em> Exon 20 Insertions
Open the PDF for Response to Standard Therapies and Comprehensive Genomic Analysis for Patients with Lung Adenocarcinoma with <em>EGFR</em> Exon 20 Insertions in another window
Includes: Supplementary data
Journal Articles

KRASG12C Mutation Is Associated with Increased Risk of Recurrence in Surgically Resected Lung Adenocarcinoma

Gregory D. Jones, Raul Caso, Kay See Tan, Brooke Mastrogiacomo, Francisco Sanchez-Vega, Yuan Liu, James G. Connolly, Yonina R. Murciano-Goroff, Matthew J. Bott, Prasad S. Adusumilli, Daniela Molena, Gaetano Rocco, Valerie W. Rusch, Smita Sihag, Sandra Misale, Rona Yaeger, Alexander Drilon, Kathryn C. Arbour, Gregory J. Riely, Neal Rosen, Piro Lito, Haiying Zhang, David C. Lyden, Charles M. Rudin, David R. Jones, Bob T. Li, James M. Isbell
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (9): 2604–2612.
https://doi.org/10.1158/1078-0432.CCR-20-4772
Published: 01 May 2021
View article titled, <em>KRAS</em><sup>G12C</sup> Mutation Is Associated with Increased Risk of Recurrence in Surgically Resected Lung Adenocarcinoma
Open the PDF for <em>KRAS</em><sup>G12C</sup> Mutation Is Associated with Increased Risk of Recurrence in Surgically Resected Lung Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Treatment Outcomes and Clinical Characteristics of Patients with KRAS-G12C–Mutant Non–Small Cell Lung Cancer

Kathryn C. Arbour, Hira Rizvi, Andrew J. Plodkowski, Matthew D. Hellmann, Andrea Knezevic, Glenn Heller, Helena A. Yu, Marc Ladanyi, Mark G. Kris, Maria E. Arcila, Charles M. Rudin, Piro Lito, Gregory J. Riely
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (8): 2209–2215.
https://doi.org/10.1158/1078-0432.CCR-20-4023
Published: 15 April 2021
View article titled, Treatment Outcomes and Clinical Characteristics of Patients with KRAS-G12C–Mutant Non–Small Cell Lung Cancer
Open the PDF for Treatment Outcomes and Clinical Characteristics of Patients with KRAS-G12C–Mutant Non–Small Cell Lung Cancer in another window
Journal Articles

The Genomic Landscape of SMARCA4 Alterations and Associations with Outcomes in Patients with Lung Cancer

Adam J. Schoenfeld, Chai Bandlamudi, Jessica A. Lavery, Joseph Montecalvo, Azadeh Namakydoust, Hira Rizvi, Jacklynn Egger, Carla P. Concepcion, Sonal Paul, Maria E. Arcila, Yahya Daneshbod, Jason Chang, Jennifer L. Sauter, Amanda Beras, Marc Ladanyi, Tyler Jacks, Charles M. Rudin, Barry S. Taylor, Mark T.A. Donoghue, Glenn Heller, Matthew D. Hellmann, Natasha Rekhtman, Gregory J. Riely
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (21): 5701–5708.
https://doi.org/10.1158/1078-0432.CCR-20-1825
Published: 02 November 2020
View article titled, The Genomic Landscape of <em>SMARCA4</em> Alterations and Associations with Outcomes in Patients with Lung Cancer
Open the PDF for The Genomic Landscape of <em>SMARCA4</em> Alterations and Associations with Outcomes in Patients with Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 12: Characterizing KRAS G12C and other mutations in plasma ctDNA from patients with lung cancer

Yonina R. Murciano-Goroff, Emily S. Lebow, Hai-Yan Tu, Mark Li, Lee P. Lim, Kathryn C. Arbour, William Travis, David B. Solit, Marc Ladanyi, David R. Jones, Charles M. Rudin, Andres Martinez, Mackenzie L. Myers, Alexander Makhnin, Pedram Razavi, Michael D. Offin, James W. Isbell, Gregory J. Riely, David M. Hyman, Piro Lito, Bob T. Li
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (12_Supplement_1): 12.
https://doi.org/10.1158/1557-3265.ADVPRECMED20-12
Published: 15 June 2020
View article titled, Abstract 12: Characterizing KRAS G12C and other mutations in plasma ctDNA from patients with lung cancer
Journal Articles

MAPK Pathway Alterations Correlate with Poor Survival and Drive Resistance to Therapy in Patients with Lung Cancers Driven by ROS1 Fusions

Hiroki Sato, Adam J. Schoenfeld, Evan Siau, Yue Christine Lu, Huichun Tai, Ken Suzawa, Daisuke Kubota, Allan J.W. Lui, Besnik Qeriqi, Marissa Mattar, Michael Offin, Masakiyo Sakaguchi, Shinichi Toyooka, Alexander Drilon, Neal X. Rosen, Mark G. Kris, David Solit, Elisa De Stanchina, Monika A. Davare, Gregory J. Riely, Marc Ladanyi, Romel Somwar
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (12): 2932–2945.
https://doi.org/10.1158/1078-0432.CCR-19-3321
Published: 15 June 2020
View article titled, MAPK Pathway Alterations Correlate with Poor Survival and Drive Resistance to Therapy in Patients with Lung Cancers Driven by <em>ROS1</em> Fusions
Open the PDF for MAPK Pathway Alterations Correlate with Poor Survival and Drive Resistance to Therapy in Patients with Lung Cancers Driven by <em>ROS1</em> Fusions in another window
Includes: Supplementary data
Journal Articles

Tumor Analyses Reveal Squamous Transformation and Off-Target Alterations As Early Resistance Mechanisms to First-line Osimertinib in EGFR-Mutant Lung Cancer

Adam J. Schoenfeld, Joseph M. Chan, Daisuke Kubota, Hiroki Sato, Hira Rizvi, Yahya Daneshbod, Jason C. Chang, Paul K. Paik, Michael Offin, Maria E. Arcila, Monika A. Davare, Ujwal Shinde, Dana Pe'er, Natasha Rekhtman, Mark G. Kris, Romel Somwar, Gregory J. Riely, Marc Ladanyi, Helena A. Yu
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (11): 2654–2663.
https://doi.org/10.1158/1078-0432.CCR-19-3563
Published: 01 June 2020
View article titled, Tumor Analyses Reveal Squamous Transformation and Off-Target Alterations As Early Resistance Mechanisms to First-line Osimertinib in <em>EGFR</em>-Mutant Lung Cancer
Open the PDF for Tumor Analyses Reveal Squamous Transformation and Off-Target Alterations As Early Resistance Mechanisms to First-line Osimertinib in <em>EGFR</em>-Mutant Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Trametinib Activity in Patients with Solid Tumors and Lymphomas Harboring BRAF Non-V600 Mutations or Fusions: Results from NCI-MATCH (EAY131)

Douglas B. Johnson, Fengmin Zhao, Marcus Noel, Gregory J. Riely, Edith P. Mitchell, John J. Wright, Helen X. Chen, Robert J. Gray, Shuli Li, Lisa M. McShane, Larry V. Rubinstein, David Patton, P. Mickey Williams, Stanly R. Hamilton, Barbara A. Conley, Carlos L. Arteaga, Lyndsay N. Harris, Peter J. O'Dwyer, Alice P. Chen, Keith T. Flaherty
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (8): 1812–1819.
https://doi.org/10.1158/1078-0432.CCR-19-3443
Published: 15 April 2020
View article titled, Trametinib Activity in Patients with Solid Tumors and Lymphomas Harboring BRAF Non-V600 Mutations or Fusions: Results from NCI-MATCH (EAY131)
Open the PDF for Trametinib Activity in Patients with Solid Tumors and Lymphomas Harboring BRAF Non-V600 Mutations or Fusions: Results from NCI-MATCH (EAY131) in another window
Includes: Supplementary data
Journal Articles

Comprehensive Next-Generation Sequencing Unambiguously Distinguishes Separate Primary Lung Carcinomas From Intrapulmonary Metastases: Comparison with Standard Histopathologic Approach

Jason C. Chang, Deepu Alex, Matthew Bott, Kay See Tan, Venkatraman Seshan, Andrew Golden, Jennifer L. Sauter, Darren J. Buonocore, Chad M. Vanderbilt, Sounak Gupta, Patrice Desmeules, Francis M. Bodd, Gregory J. Riely, Valerie W. Rusch, David R. Jones, Maria E. Arcila, William D. Travis, Marc Ladanyi, Natasha Rekhtman
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (23): 7113–7125.
https://doi.org/10.1158/1078-0432.CCR-19-1700
Published: 02 December 2019
View article titled, Comprehensive Next-Generation Sequencing Unambiguously Distinguishes Separate Primary Lung Carcinomas From Intrapulmonary Metastases: Comparison with Standard Histopathologic Approach
Open the PDF for Comprehensive Next-Generation Sequencing Unambiguously Distinguishes Separate Primary Lung Carcinomas From Intrapulmonary Metastases: Comparison with Standard Histopathologic Approach in another window
Includes: Supplementary data
Journal Articles

Tumor Mutation Burden and Efficacy of EGFR-Tyrosine Kinase Inhibitors in Patients with EGFR-Mutant Lung Cancers

Michael Offin, Hira Rizvi, Megan Tenet, Andy Ni, Francisco Sanchez-Vega, Bob T. Li, Alexander Drilon, Mark G. Kris, Charles M. Rudin, Nikolaus Schultz, Maria E. Arcila, Marc Ladanyi, Gregory J. Riely, Helena Yu, Matthew D. Hellmann
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (3): 1063–1069.
https://doi.org/10.1158/1078-0432.CCR-18-1102
Published: 01 February 2019
View article titled, Tumor Mutation Burden and Efficacy of EGFR-Tyrosine Kinase Inhibitors in Patients with <em>EGFR</em>-Mutant Lung Cancers
Open the PDF for Tumor Mutation Burden and Efficacy of EGFR-Tyrosine Kinase Inhibitors in Patients with <em>EGFR</em>-Mutant Lung Cancers in another window
Includes: Supplementary data
Journal Articles

Concurrent Alterations in EGFR-Mutant Lung Cancers Associated with Resistance to EGFR Kinase Inhibitors and Characterization of MTOR as a Mediator of Resistance

Helena A. Yu, Ken Suzawa, Emmet Jordan, Ahmet Zehir, Ai Ni, Ryan Kim, Mark G. Kris, Matthew D. Hellmann, Bob T. Li, Romel Somwar, David B. Solit, Michael F. Berger, Maria Arcila, Gregory J. Riely, Marc Ladanyi
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (13): 3108–3118.
https://doi.org/10.1158/1078-0432.CCR-17-2961
Published: 01 July 2018
View article titled, Concurrent Alterations in EGFR-Mutant Lung Cancers Associated with Resistance to EGFR Kinase Inhibitors and Characterization of MTOR as a Mediator of Resistance
Open the PDF for Concurrent Alterations in EGFR-Mutant Lung Cancers Associated with Resistance to EGFR Kinase Inhibitors and Characterization of MTOR as a Mediator of Resistance in another window
Includes: Supplementary data
Journal Articles

Effects of Co-occurring Genomic Alterations on Outcomes in Patients with KRAS-Mutant Non–Small Cell Lung Cancer

Kathryn C. Arbour, Emmett Jordan, Hyunjae Ryan Kim, Jordan Dienstag, Helena A. Yu, Francisco Sanchez-Vega, Piro Lito, Michael Berger, David B. Solit, Matthew Hellmann, Mark G. Kris, Charles M. Rudin, Ai Ni, Maria Arcila, Marc Ladanyi, Gregory J. Riely
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (2): 334–340.
https://doi.org/10.1158/1078-0432.CCR-17-1841
Published: 15 January 2018
View article titled, Effects of Co-occurring Genomic Alterations on Outcomes in Patients with <em>KRAS</em>-Mutant Non–Small Cell Lung Cancer
Open the PDF for Effects of Co-occurring Genomic Alterations on Outcomes in Patients with <em>KRAS</em>-Mutant Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Antitumor Activity of RXDX-105 in Multiple Cancer Types with RET Rearrangements or Mutations

Gang G. Li, Romel Somwar, James Joseph, Roger S. Smith, Takuo Hayashi, Leenus Martin, Aleksandra Franovic, Anni Schairer, Eric Martin, Gregory J. Riely, Jason Harris, Shunqi Yan, Ge Wei, Jennifer W. Oliver, Rupal Patel, Pratik Multani, Marc Ladanyi, Alexander Drilon
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (12): 2981–2990.
https://doi.org/10.1158/1078-0432.CCR-16-1887
Published: 14 June 2017
View article titled, Antitumor Activity of RXDX-105 in Multiple Cancer Types with <em>RET</em> Rearrangements or Mutations
Open the PDF for Antitumor Activity of RXDX-105 in Multiple Cancer Types with <em>RET</em> Rearrangements or Mutations in another window
Includes: Supplementary data
Journal Articles

A Novel Crizotinib-Resistant Solvent-Front Mutation Responsive to Cabozantinib Therapy in a Patient with ROS1-Rearranged Lung Cancer

Alexander Drilon, Romel Somwar, Jacob P. Wagner, Nadeem A. Vellore, Christopher A. Eide, Matthew S. Zabriskie, Maria E. Arcila, Jaclyn F. Hechtman, Lu Wang, Roger S. Smith, Mark G. Kris, Gregory J. Riely, Brian J. Druker, Thomas O'Hare, Marc Ladanyi, Monika A. Davare
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (10): 2351–2358.
https://doi.org/10.1158/1078-0432.CCR-15-2013
Published: 12 May 2016
View article titled, A Novel Crizotinib-Resistant Solvent-Front Mutation Responsive to Cabozantinib Therapy in a Patient with <em>ROS1</em>-Rearranged Lung Cancer
Open the PDF for A Novel Crizotinib-Resistant Solvent-Front Mutation Responsive to Cabozantinib Therapy in a Patient with <em>ROS1</em>-Rearranged Lung Cancer in another window
Includes: Supplementary data