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Glenn J. Hanna
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Journal Articles

Duvelisib with Docetaxel for Patients with Anti–PD-1 Refractory, Recurrent, or Metastatic Head and Neck Squamous Cell Carcinoma

Glenn J. Hanna, L. B. Oakley, R. Shi, A. ONeill, K. Y. Shin, N. Scarfo, K. Sehgal, M. J. Dennis, N. Quinn, V. Y. Jo, K. Wong, A. Shvyrkova, V. Kushnarev, B. U. Shanthappa, A. Tkachuk, K. Kryukov, A. Sarachakov, V. Svekolkin, J. Lennerz, S. Waters, R. I. Haddad
Journal: Clinical Cancer Research
Clin Cancer Res (2025) 31 (4): 619–627.
https://doi.org/10.1158/1078-0432.CCR-24-2262
Published: 17 February 2025
View articletitled, Duvelisib with Docetaxel for Patients with Anti–PD-1 Refractory, Recurrent, or Metastatic Head and Neck Squamous Cell Carcinoma
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Includes: Supplementary data
Journal Articles

A Prospective Trial of Biomarker-Guided Surveillance for HPV-Positive Oropharynx Cancer Using Plasma Tumor Tissue–Modified Viral HPV DNA

Eleni M. Rettig, Jonathan D. Schoenfeld, Julianna Miller, Bethany Sargent, Evan Carey, Danielle N. Margalit, Kartik Sehgal, Rosh K.V. Sethi, Ravindra Uppaluri, Roy B. Tishler, Laura A. Goguen, Donald J. Annino, Edward S. Sim, Vickie Y. Jo, Kristine S. Wong, Jeffrey P. Guenette, Robert I. Haddad, Glenn J. Hanna
Journal: Clinical Cancer Research
Clin Cancer Res OF1–OF10.
https://doi.org/10.1158/1078-0432.CCR-24-3053
Published: 13 January 2025
View articletitled, A Prospective Trial of Biomarker-Guided Surveillance for HPV-Positive Oropharynx Cancer Using Plasma Tumor Tissue–Modified Viral HPV DNA
Open the PDF for A Prospective Trial of Biomarker-Guided Surveillance for HPV-Positive Oropharynx Cancer Using Plasma Tumor Tissue–Modified Viral HPV DNA in another window
Includes: Supplementary data
Journal Articles

Abstract B022: Immediate post-treatment detection of minimal residual disease in HPV-Driven oropharyngeal cancer is associated with high risk of recurrence

Scott A Roof, James Jabalee, Eleni M Rettig, Rocco Ferrandino, Sida Chen, Marshall R Posner, Krzysztof J Misiukiewicz, Eric M Gender, Raymond L Chai, John Sims, Elaine Thrash, Scott J Stern, Noah S Kalman, Sreenija Yarlagadda, Adam Raben, Lydia Clements, Abie Mendelsohn, John M Kaczmar, Yadav Pandey, Mihir Bhayani, Catherine DV Fitz, Glenn J Hanna
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (21_Supplement): B022.
https://doi.org/10.1158/1557-3265.LIQBIOP24-B022
Published: 13 November 2024
View articletitled, Abstract B022: Immediate post-treatment detection of minimal residual disease in HPV-Driven oropharyngeal cancer is associated with high risk of recurrence
Journal Articles

Abstract B024: Personalized tumor-informed circulating tumor (ct) DNA for advanced thyroid carcinoma

Kartik Sehgal, Theodora Pappa, Michael J. Dennis, Nicole J. Scarfo, Michelle S. Mullin, Tura Coombs, Roy B. Tishler, Danielle N. Margalit, Ravindra Uppaluri, Rosh K. Sethi, Jonathan D. Schoenfeld, Justine A. Barletta, Gerard M. Doherty, Erik K. Alexander, Laura A. Goguen, Eleni M. Rettig, Robert I. Haddad, Glenn J. Hanna
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (21_Supplement): B024.
https://doi.org/10.1158/1557-3265.LIQBIOP24-B024
Published: 13 November 2024
View articletitled, Abstract B024: Personalized tumor-informed circulating tumor (ct) DNA for advanced thyroid carcinoma
Journal Articles

Personalized ctDNA for Monitoring Disease Status in Head and Neck Squamous Cell Carcinoma

Glenn J. Hanna, Michael J. Dennis, Nicole Scarfo, Michelle S. Mullin, Rosh K.V. Sethi, Kartik Sehgal, Donald J. Annino, Jr, Laura A. Goguen, Robert I. Haddad, Roy B. Tishler, Danielle N. Margalit, Ravindra Uppaluri, Jonathan D. Schoenfeld, Eleni M. Rettig
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (15): 3329–3336.
https://doi.org/10.1158/1078-0432.CCR-24-0590
Published: 01 August 2024
View articletitled, Personalized ctDNA for Monitoring Disease Status in Head and Neck Squamous Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Molecular Profiling and the Impact of Treatment on Outcomes in Adenoid Cystic Carcinoma Type I and II

Glenn J. Hanna, Punita Grover, Andrew Elliott, Julie McGrath, Joanne Xiu, Ammar Sukari, Jennifer M. Johnson, Trisha Wise-Draper
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (10): 2225–2232.
https://doi.org/10.1158/1078-0432.CCR-23-3182
Published: 15 May 2024
View articletitled, Molecular Profiling and the Impact of Treatment on Outcomes in Adenoid Cystic Carcinoma Type I and II
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Includes: Supplementary data
Journal Articles

A Phase II Trial of Rivoceranib, an Oral Vascular Endothelial Growth Factor Receptor 2 Inhibitor, for Recurrent or Metastatic Adenoid Cystic Carcinoma

Glenn J. Hanna, Myung-Ju Ahn, Jameel Muzaffar, Bhumsuk Keam, Daniel W. Bowles, Deborah J. Wong, Alan L. Ho, Sung-Bae Kim, Francis Worden, Tak Yun, Xianzhang Meng, Jan M. Van Tornout, Maureen G. Conlan, Hyunseok Kang
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (22): 4555–4563.
https://doi.org/10.1158/1078-0432.CCR-23-1030
Published: 14 November 2023
View articletitled, A Phase II Trial of Rivoceranib, an Oral Vascular Endothelial Growth Factor Receptor 2 Inhibitor, for Recurrent or Metastatic Adenoid Cystic Carcinoma
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Includes: Supplementary data
Journal Articles

Negative Predictive Value of Circulating Tumor Tissue Modified Viral (TTMV)-HPV DNA for HPV-driven Oropharyngeal Cancer Surveillance

Glenn J. Hanna, Scott A. Roof, Jamie Jabalee, Eleni M. Rettig, Rocco Ferrandino, II, Sida Chen, Marshall R. Posner, Krzysztof J. Misiukiewicz, Eric M. Genden, Raymond L. Chai, John Sims, Elaine Thrash, Scott J. Stern, Noah S. Kalman, Sreenija Yarlagadda, Adam Raben, Lydia Clements, Abie Mendelsohn, John M. Kaczmar, Yadav Pandey, Mihir Bhayani, Piyush Gupta, Charlotte Kuperwasser, Catherine Del Vecchio Fitz, Barry M. Berger
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (20): 4306–4313.
https://doi.org/10.1158/1078-0432.CCR-23-1478
Published: 13 October 2023
View articletitled, Negative Predictive Value of Circulating Tumor Tissue Modified Viral (TTMV)-HPV DNA for HPV-driven Oropharyngeal Cancer Surveillance
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Includes: Supplementary data
Journal Articles

Abstract PO-046: Relationship of HPV16 E6 seropositivity with circulating tumor tissue modified HPV DNA before head and neck cancer diagnosis

Eleni M. Rettig, Tim Waterboer, Edward S. Sim, Daniel L. Faden, Glenn J. Hanna, Catherine Del Vecchio Fitz, Charlotte Kuperwasser, Herve Sroussi
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (18_Supplement): PO-046.
https://doi.org/10.1158/1557-3265.AACRAHNS23-PO-046
Published: 15 September 2023
View articletitled, Abstract PO-046: Relationship of HPV16 E6 seropositivity with circulating tumor tissue modified HPV DNA before head and neck cancer diagnosis
Journal Articles

Abstract PR11: Allogeneic memory-like natural killer (NK) cell therapy with IL-15 superagonist with or without ipilimumab for advanced, incurable head and neck cancer: A phase 1 trial

Glenn J. Hanna, Roman M. Shapiro, Michal Sheffer, Michela Ansuinelli, Grace Birch, Robert A. Redd, Alejandro Alonso, Denbaa Bat-Erdene, Samantha Himberg, Heather Daley, Diego E. Hernandez-Rodriquez, Katharin L. Shaw, Jerome Ritz, Sarah Nikiforow, Robert J. Soiffer, Rizwan Romee
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (18_Supplement): PR11.
https://doi.org/10.1158/1557-3265.AACRAHNS23-PR11
Published: 15 September 2023
View articletitled, Abstract PR11: Allogeneic memory-like natural killer (NK) cell therapy with IL-15 superagonist with or without ipilimumab for advanced, incurable head and neck cancer: A phase 1 trial
Journal Articles

Detection of Occult Recurrence Using Circulating Tumor Tissue Modified Viral HPV DNA among Patients Treated for HPV-Driven Oropharyngeal Carcinoma

Barry M. Berger, Glenn J. Hanna, Marshall R. Posner, Eric M. Genden, Julio Lautersztain, Stephen P. Naber, Catherine Del Vecchio Fitz, Charlotte Kuperwasser
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (19): 4292–4301.
https://doi.org/10.1158/1078-0432.CCR-22-0562
Published: 03 October 2022
View articletitled, Detection of Occult Recurrence Using Circulating Tumor Tissue Modified Viral HPV DNA among Patients Treated for HPV-Driven Oropharyngeal Carcinoma
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Journal Articles

Report of the First International Symposium on NUT Carcinoma

Christopher A. French, Michael L. Cheng, Glenn J. Hanna, Steven G. DuBois, Nicole G. Chau, Christine L. Hann, Simone Storck, Ravi Salgia, Matteo Trucco, Jennifer Tseng, Anastasios Stathis, Richard Piekarz, Ulrich M. Lauer, Christophe Massard, Kelly Bennett, Shodeinde Coker, Ulrike Tontsch-Grunt, Martin L. Sos, Sida Liao, Catherine J. Wu, Kornelia Polyak, Sarina A. Piha-Paul, Geoffrey I. Shapiro
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (12): 2493–2505.
https://doi.org/10.1158/1078-0432.CCR-22-0591
Published: 13 June 2022
View articletitled, Report of the First International Symposium on NUT Carcinoma
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Journal Articles

Neoadjuvant and Adjuvant Nivolumab and Lirilumab in Patients with Recurrent, Resectable Squamous Cell Carcinoma of the Head and Neck

Glenn J. Hanna, Anne O'Neill, Kee-Young Shin, Kristine Wong, Vickie Y. Jo, Charles T. Quinn, Jennifer M. Cutler, Michelle Flynn, Patrick H. Lizotte, Donald J. Annino, Jr, Laura A. Goguen, Jason I. Kass, Eleni M. Rettig, Rosh K.V. Sethi, Jochen H. Lorch, Jonathan D. Schoenfeld, Danielle N. Margalit, Roy B. Tishler, Peter C. Everett, Anupam M. Desai, Megan E. Cavanaugh, Cloud P. Paweletz, Ann Marie Egloff, Ravindra Uppaluri, Robert I. Haddad
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (3): 468–478.
https://doi.org/10.1158/1078-0432.CCR-21-2635
Published: 01 February 2022
View articletitled, Neoadjuvant and Adjuvant Nivolumab and Lirilumab in Patients with Recurrent, Resectable Squamous Cell Carcinoma of the Head and Neck
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Includes: Supplementary data
Journal Articles

Correction: Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus–unrelated Head and Neck Cancer: A Multicenter, Phase II Trial

Ravindra Uppaluri, Katie M. Campbell, Ann Marie Egloff, Paul Zolkind, Zachary L. Skidmore, Brian Nussenbaum, Randal C. Paniello, Jason T. Rich, Ryan Jackson, Patrik Pipkorn, Loren S. Michel, Jessica Ley, Peter Oppelt, Gavin P. Dunn, Erica K. Barnell, Nicholas C. Spies, Tianxiang Lin, Tiantian Li, David T. Mulder, Youstina Hanna, Iulia Cirlan, Trevor J. Pugh, Tenny Mudianto, Rachel Riley, Liye Zhou, Vickie Y. Jo, Matthew D. Stachler, Glenn J. Hanna, Jason Kass, Robert Haddad, Jonathan D. Schoenfeld, Evisa Gjini, Ana Lako, Wade Thorstad, Hiram A. Gay, Mackenzie Daly, Scott J. Rodig, Ian S. Hagemann, Dorina Kallogjeri, Jay F. Piccirillo, Rebecca D. Chernock, Malachi Griffith, Obi L. Griffith, Douglas R. Adkins
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (1): 357.
https://doi.org/10.1158/1078-0432.CCR-20-4484
Published: 04 January 2021
View articletitled, Correction: Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus–unrelated Head and Neck Cancer: A Multicenter, Phase II Trial
Open the PDF for Correction: Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus–unrelated Head and Neck Cancer: A Multicenter, Phase II Trial in another window
Journal Articles

Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus–Unrelated Head and Neck Cancer: A Multicenter, Phase II Trial

Ravindra Uppaluri, Katie M. Campbell, Ann Marie Egloff, Paul Zolkind, Zachary L. Skidmore, Brian Nussenbaum, Randal C. Paniello, Jason T. Rich, Ryan Jackson, Patrik Pipkorn, Loren S. Michel, Jessica Ley, Peter Oppelt, Gavin P. Dunn, Erica K. Barnell, Nicholas C. Spies, Tianxiang Lin, Tiantian Li, David T. Mulder, Youstina Hanna, Iulia Cirlan, Trevor J. Pugh, Tenny Mudianto, Rachel Riley, Liye Zhou, Vickie Y. Jo, Matthew D. Stachler, Glenn J. Hanna, Jason Kass, Robert Haddad, Jonathan D. Schoenfeld, Evisa Gjini, Ana Lako, Wade Thorstad, Hiram A. Gay, Mackenzie Daly, Scott J. Rodig, Ian S. Hagemann, Dorina Kallogjeri, Jay F. Piccirillo, Rebecca D. Chernock, Malachi Griffith, Obi L. Griffith, Douglas R. Adkins
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (19): 5140–5152.
https://doi.org/10.1158/1078-0432.CCR-20-1695
Published: 01 October 2020
View articletitled, Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus–Unrelated Head and Neck Cancer: A Multicenter, Phase II Trial
Open the PDF for Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus–Unrelated Head and Neck Cancer: A Multicenter, Phase II Trial in another window
Includes: Supplementary data
Journal Articles

Genomic Correlates of Response to Everolimus in Aggressive Radioiodine-refractory Thyroid Cancer: A Phase II Study

Glenn J. Hanna, Naifa L. Busaidy, Nicole G. Chau, Lori J. Wirth, Justine A. Barletta, Antonio Calles, Robert I. Haddad, Stefan Kraft, Maria E. Cabanillas, Guilherme Rabinowits, Anne O'Neill, Sewanti A. Limaye, Erik K. Alexander, Francis D. Moore, Jr, Krystof Misiwkeiwicz, Tom Thomas, Matthew Nehs, Ellen Marqusee, Stephanie L. Lee, Pasi A. Jänne, Jochen H. Lorch
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (7): 1546–1553.
https://doi.org/10.1158/1078-0432.CCR-17-2297
Published: 02 April 2018
View articletitled, Genomic Correlates of Response to Everolimus in Aggressive Radioiodine-refractory Thyroid Cancer: A Phase II Study
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Includes: Supplementary data
Journal Articles

Genomic Heterogeneity and Exceptional Response to Dual Pathway Inhibition in Anaplastic Thyroid Cancer

William J. Gibson, Daniel T. Ruan, Vera A. Paulson, Justine A. Barletta, Glenn J. Hanna, Stefan Kraft, Antonio Calles, Matthew A. Nehs, Francis D. Moore, Jr, Amaro Taylor-Weiner, Jeremiah A. Wala, Travis I. Zack, Thomas C. Lee, Fiona M. Fennessy, Erik K. Alexander, Tom Thomas, Pasi A. Janne, Levi A. Garraway, Scott L. Carter, Rameen Beroukhim, Jochen H. Lorch, Eliezer M. Van Allen
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (9): 2367–2373.
https://doi.org/10.1158/1078-0432.CCR-16-2154-T
Published: 30 April 2017
View articletitled, Genomic Heterogeneity and Exceptional Response to Dual Pathway Inhibition in Anaplastic Thyroid Cancer
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Includes: Supplementary data
Journal Articles

Genomic Analysis of Metastatic Cutaneous Squamous Cell Carcinoma

Yvonne Y. Li, Glenn J. Hanna, Alvaro C. Laga, Robert I. Haddad, Jochen H. Lorch, Peter S. Hammerman
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (6): 1447–1456.
https://doi.org/10.1158/1078-0432.CCR-14-1773
Published: 12 March 2015
View articletitled, Genomic Analysis of Metastatic Cutaneous Squamous Cell Carcinoma
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Includes: Supplementary data