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Gerrit A. Meijer
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Journal Articles

Abstract PR016: Dynamic chromatin landscapes of colorectal cancer development and cell-free DNA fragmentation

Nicholas A. Vulpescu, Zachariah H. Foda, Pieter H.A. Wisse, Christopher Cherry, Jaime E. Medina, Vilmos Adleff, Remond J.A. Fijneman, Robert B. Scharpf, Gerrit A. Meijer, Beatriz Carvalho, Victor E. Velculescu
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (21_Supplement): PR016.
https://doi.org/10.1158/1557-3265.LIQBIOP24-PR016
Published: 13 November 2024
View article titled, Abstract PR016: Dynamic chromatin landscapes of colorectal cancer development and cell-free DNA fragmentation
Journal Articles

Abstract B067: Dynamic chromatin landscapes of colorectal cancer development and cell-free DNA fragmentation

Nicholas A. Vulpescu, Zachariah H. Foda, Pieter H.A. Wisse, Christopher Cherry, Jaime E. Medina, Vilmos Adleff, Remond J.A. Fijneman, Robert B. Scharpf, Gerrit A. Meijer, Beatriz Carvalho, Victor E. Velculescu
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (21_Supplement): B067.
https://doi.org/10.1158/1557-3265.LIQBIOP24-B067
Published: 13 November 2024
View article titled, Abstract B067: Dynamic chromatin landscapes of colorectal cancer development and cell-free DNA fragmentation
Journal Articles

A Dysfunctional T-cell Gene Signature for Predicting Nonresponse to PD-1 Blockade in Non–small Cell Lung Cancer That Is Suitable for Routine Clinical Diagnostics

Karlijn Hummelink, Renaud Tissier, Linda J.W. Bosch, Oscar Krijgsman, Michel M. van den Heuvel, Willemijn S.M.E. Theelen, Diane Damotte, François Goldwasser, Karen Leroy, Egbert F. Smit, Gerrit A. Meijer, Daniela S. Thommen, Kim Monkhorst
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (4): 814–823.
https://doi.org/10.1158/1078-0432.CCR-23-1061
Published: 16 February 2024
View article titled, A Dysfunctional T-cell Gene Signature for Predicting Nonresponse to PD-1 Blockade in Non–small Cell Lung Cancer That Is Suitable for Routine Clinical Diagnostics
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Includes: Supplementary data
Journal Articles

Metastatic Colorectal Cancer Treatment Response Evaluation by Ultra-Deep Sequencing of Cell-Free DNA and Matched White Blood Cells

Iris van 't Erve, Jamie E. Medina, Alessandro Leal, Eniko Papp, Jillian Phallen, Vilmos Adleff, Elaine Jiayuee Chiao, Adith S. Arun, Karen Bolhuis, John K. Simmons, Aanavi Karandikar, Kenneth C. Valkenburg, Mark Sausen, Samuel V. Angiuoli, Robert B. Scharpf, Cornelis J.A. Punt, Gerrit A. Meijer, Victor E. Velculescu, Remond J.A. Fijneman
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (5): 899–909.
https://doi.org/10.1158/1078-0432.CCR-22-2538
Published: 01 March 2023
View article titled, Metastatic Colorectal Cancer Treatment Response Evaluation by Ultra-Deep Sequencing of Cell-Free DNA and Matched White Blood Cells
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Includes: Supplementary data
Journal Articles

PD-1T TILs as a Predictive Biomarker for Clinical Benefit to PD-1 Blockade in Patients with Advanced NSCLC

Karlijn Hummelink, Vincent van der Noort, Mirte Muller, Robert D. Schouten, Ferry Lalezari, Dennis Peters, Willemijn S.M.E. Theelen, Viktor H. Koelzer, Kirsten D. Mertz, Alfred Zippelius, Michel M. van den Heuvel, Annegien Broeks, John B.A.G. Haanen, Ton N. Schumacher, Gerrit A. Meijer, Egbert F. Smit, Kim Monkhorst, Daniela S. Thommen
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (22): 4893–4906.
https://doi.org/10.1158/1078-0432.CCR-22-0992
Published: 14 November 2022
View article titled, PD-1<sup>T</sup> TILs as a Predictive Biomarker for Clinical Benefit to PD-1 Blockade in Patients with Advanced NSCLC
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Includes: Supplementary data
Journal Articles

Pathology: Hub and Integrator of Modern, Multidisciplinary [Precision] Oncology

The AACR Pathology Task Force, Carolyn C. Compton, Angelo M. De Marzo, Jayanta Debnath, Keith D. Eaton, Kojo Elenitoba-Johnson, Michelangelo Fiorentino, Christopher A. French, Thomas J. Fuchs, Felice Giangaspero, Jiaoti Huang, A. John Iafrate, Michael M. Ittmann, Roy A. Jensen, Annette S. Kim, Massimo Loda, Robin G. Lorenz, Tamara L. Lotan, Anirban Maitra, Gerrit A. Meijer, Richard N. Mitchell, Anil V. Parwani, Francesco Pezzella, Eli Pikarsky, Jorge S. Reis-Filho, Andrea L. Richardson, Mark A. Rubin, Lawrence D. True
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (2): 265–270.
https://doi.org/10.1158/1078-0432.CCR-21-1206
Published: 19 January 2022
View article titled, Pathology: Hub and Integrator of Modern, Multidisciplinary [Precision] Oncology
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Journal Articles

Abstract A62: Clinical translation of liquid biopsy DNA methylation biomarkers: Lessons from two systematic reviews

Kim Lommen, Zheng Feng, Cary J.G. Oberije, Alouisa J. P. van de Wetering, Selena Odeh, Alexander Koch, Maureen J. B. Aarts, Joep G. van Roermund, Leo J. Schouten, Egbert Oosterwijk, Nathalie Vaes, Ad A. M. Masclee, Beatriz Carvalho, Gerrit A. Meijer, Maurice P. Zeegers, James G. Herman, Vivianne C. Tjan-Heijnen, Veerle Melotte, Manon van Engeland, Kim Smits
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (11_Supplement): A62.
https://doi.org/10.1158/1557-3265.LiqBiop20-A62
Published: 01 June 2020
View article titled, Abstract A62: Clinical translation of liquid biopsy DNA methylation biomarkers: Lessons from two systematic reviews
Journal Articles

WRN Promoter CpG Island Hypermethylation Does Not Predict More Favorable Outcomes for Patients with Metastatic Colorectal Cancer Treated with Irinotecan-Based Therapy

Linda J.W. Bosch, Yanxin Luo, Victoria V. Lao, Petur Snaebjornsson, Geert Trooskens, Ilse Vlassenbroeck, Sandra Mongera, Weiliang Tang, Piri Welcsh, James G. Herman, Miriam Koopman, Iris D. Nagtegaal, Cornelis J.A. Punt, Wim van Criekinge, Gerrit A. Meijer, Raymond J. Monnat, Jr, Beatriz Carvalho, William M. Grady
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (18): 4612–4622.
https://doi.org/10.1158/1078-0432.CCR-15-2703
Published: 15 September 2016
View article titled, <em>WRN</em> Promoter CpG Island Hypermethylation Does Not Predict More Favorable Outcomes for Patients with Metastatic Colorectal Cancer Treated with Irinotecan-Based Therapy
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Includes: Supplementary data
Journal Articles

Extent and Location of Tumor-Infiltrating Lymphocytes in Microsatellite-Stable Colon Cancer Predict Outcome to Adjuvant Active Specific Immunotherapy

Annelies W. Turksma, Veerle M.H. Coupé, Marc C. Shamier, Kevin L.H. Lam, Vincent A. de Weger, Jeroen A.M. Belien, Alfons J. van den Eertwegh, Gerrit A. Meijer, Chris J.L.M. Meijer, Erik Hooijberg
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (2): 346–356.
https://doi.org/10.1158/1078-0432.CCR-13-2462
Published: 14 January 2016
View article titled, Extent and Location of Tumor-Infiltrating Lymphocytes in Microsatellite-Stable Colon Cancer Predict Outcome to Adjuvant Active Specific Immunotherapy
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Journal Articles

Mismatch Repair Status and BRAF Mutation Status in Metastatic Colorectal Cancer Patients: A Pooled Analysis of the CAIRO, CAIRO2, COIN, and FOCUS Studies

Sabine Venderbosch, Iris D. Nagtegaal, Tim S. Maughan, Christopher G. Smith, Jeremy P. Cheadle, David Fisher, Richard Kaplan, Philip Quirke, Matthew T. Seymour, Susan D. Richman, Gerrit A. Meijer, Bauke Ylstra, Danielle A.M. Heideman, Anton F.J. de Haan, Cornelis J.A. Punt, Miriam Koopman
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (20): 5322–5330.
https://doi.org/10.1158/1078-0432.CCR-14-0332
Published: 14 October 2014
View article titled, Mismatch Repair Status and <em>BRAF</em> Mutation Status in Metastatic Colorectal Cancer Patients: A Pooled Analysis of the CAIRO, CAIRO2, COIN, and FOCUS Studies
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Includes: Supplementary data
Journal Articles

Alternative Cleavage and Polyadenylation during Colorectal Cancer Development

Adam R. Morris, Arnold Bos, Begoña Diosdado, Koos Rooijers, Ran Elkon, Anne S. Bolijn, Beatriz Carvalho, Gerrit A. Meijer, Reuven Agami
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (19): 5256–5266.
https://doi.org/10.1158/1078-0432.CCR-12-0543
Published: 30 September 2012
View article titled, Alternative Cleavage and Polyadenylation during Colorectal Cancer Development
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Includes: Supplementary data
Journal Articles

Chromosome 5q Loss in Colorectal Flat Adenomas

Quirinus J.M. Voorham, Beatriz Carvalho, Angela J. Spiertz, Nicole C.T. van Grieken, Sandra Mongera, Eveline J.A. Rondagh, Mark A. van de Wiel, Ekaterina S. Jordanova, Bauke Ylstra, Martin Kliment, Heike Grabsch, Bjorn J. Rembacken, Tomio Arai, Adriaan P. de Bruïne, Silvia Sanduleanu, Philip Quirke, Chris J.J. Mulder, Manon van Engeland, Gerrit A. Meijer
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (17): 4560–4569.
https://doi.org/10.1158/1078-0432.CCR-11-2385
Published: 30 August 2012
View article titled, Chromosome 5q Loss in Colorectal Flat Adenomas
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Includes: Supplementary data
Journal Articles

Proximal Fluid Proteome Profiling of Mouse Colon Tumors Reveals Biomarkers for Early Diagnosis of Human Colorectal Cancer

Remond J.A. Fijneman, Meike de Wit, Maral Pourghiasian, Sander R. Piersma, Thang V. Pham, Marc O. Warmoes, Mehrdad Lavaei, Chloe Piso, Fiona Smit, Pien M. Delis-van Diemen, Sietze T. van Turenhout, Jochim S. Terhaar sive Droste, Chris J.J. Mulder, Marinus A. Blankenstein, Els C. Robanus-Maandag, Ron Smits, Riccardo Fodde, Victor W.M. van Hinsbergh, Gerrit A. Meijer, Connie R. Jimenez
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (9): 2613–2624.
https://doi.org/10.1158/1078-0432.CCR-11-1937
Published: 30 April 2012
View article titled, Proximal Fluid Proteome Profiling of Mouse Colon Tumors Reveals Biomarkers for Early Diagnosis of Human Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Clinical Effects of Adjuvant Active Specific Immunotherapy Differ between Patients with Microsatellite-Stable and Microsatellite-Instable Colon Cancer

Vincent A. de Weger, Annelies W. Turksma, Quirinus J.M. Voorham, Zelda Euler, Herman Bril, Alfons J. van den Eertwegh, Elisabeth Bloemena, Herbert M. Pinedo, Jan B. Vermorken, Harm van Tinteren, Gerrit A. Meijer, Erik Hooijberg
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (3): 882–889.
https://doi.org/10.1158/1078-0432.CCR-11-1716
Published: 31 January 2012
View article titled, Clinical Effects of Adjuvant Active Specific Immunotherapy Differ between Patients with Microsatellite-Stable and Microsatellite-Instable Colon Cancer
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Includes: Supplementary data
Journal Articles

To DNA or not to DNA? That Is the Question, When It Comes to Molecular Subtyping for the Clinic!

Serge J. Smeets, Ulrike Harjes, Wessel N. van Wieringen, Daoud Sie, Ruud H. Brakenhoff, Gerrit A. Meijer, Bauke Ylstra
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (15): 4959–4964.
https://doi.org/10.1158/1078-0432.CCR-11-0462
Published: 31 July 2011
View article titled, To DNA or not to DNA? That Is the Question, When It Comes to Molecular Subtyping for the Clinic!
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Includes: Supplementary data
Journal Articles

High-Resolution Array Comparative Genomic Hybridization in Sporadic and Celiac Disease–Related Small Bowel Adenocarcinomas

Begoña Diosdado, Tineke E. Buffart, Russell Watkins, Beatriz Carvalho, Bauke Ylstra, Marianne Tijssen, Anne S. Bolijn, Fraser Lewis, Karen Maude, Caroline Verbeke, Iris D. Nagtegaal, Heike Grabsch, Chris J.J. Mulder, Phil Quirke, Peter Howdle, Gerrit A. Meijer
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (5): 1391–1401.
https://doi.org/10.1158/1078-0432.CCR-09-1773
Published: 28 February 2010
View article titled, High-Resolution Array Comparative Genomic Hybridization in Sporadic and Celiac Disease–Related Small Bowel Adenocarcinomas
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Includes: Supplementary data
Journal Articles

GATA4 and GATA5 are Potential Tumor Suppressors and Biomarkers in Colorectal Cancer

Debby M.E.I. Hellebrekers, Marjolein H.F.M. Lentjes, Sandra M. van den Bosch, Veerle Melotte, Kim A.D. Wouters, Kathleen L.J. Daenen, Kim M. Smits, Yoshimitsu Akiyama, Yasuhito Yuasa, Silvia Sanduleanu, Carolina A.J. Khalid-de Bakker, Daisy Jonkers, Matty P. Weijenberg, Joost Louwagie, Wim van Criekinge, Beatriz Carvalho, Gerrit A. Meijer, Stephen B. Baylin, James G. Herman, Adriaan P. de Bruïne, Manon van Engeland
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (12): 3990–3997.
https://doi.org/10.1158/1078-0432.CCR-09-0055
Published: 15 June 2009
View article titled, GATA4 and GATA5 are Potential Tumor Suppressors and Biomarkers in Colorectal Cancer
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Includes: Supplementary data
Journal Articles

DNA Copy Number Gains at Loci of Growth Factors and Their Receptors in Salivary Gland Adenoid Cystic Carcinoma

Hedy Vékony, Bauke Ylstra, Saskia M. Wilting, Gerrit A. Meijer, Mark A. van de Wiel, C. René Leemans, Isaäc van der Waal, Elisabeth Bloemena
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (11): 3133–3139.
https://doi.org/10.1158/1078-0432.CCR-06-2555
Published: 01 June 2007
View article titled, DNA Copy Number Gains at Loci of Growth Factors and Their Receptors in Salivary Gland Adenoid Cystic Carcinoma
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