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Gerhardt Attard
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Journal Articles

Blood Biomarker Landscape in Patients with High-risk Nonmetastatic Castration-Resistant Prostate Cancer Treated with Apalutamide and Androgen-Deprivation Therapy as They Progress to Metastatic Disease

Matthew R. Smith, Shibu Thomas, Michael Gormley, Simon Chowdhury, David Olmos, Stéphane Oudard, Felix Y. Feng, Yashoda Rajpurohit, Karen Urtishak, Deborah S. Ricci, Brendan Rooney, Angela Lopez-Gitlitz, Margaret Yu, Alexander W. Wyatt, Mark Li, Gerhardt Attard, Eric J. Small
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (16): 4539–4548.
https://doi.org/10.1158/1078-0432.CCR-21-0358
Published: 15 August 2021
View article titled, Blood Biomarker Landscape in Patients with High-risk Nonmetastatic Castration-Resistant Prostate Cancer Treated with Apalutamide and Androgen-Deprivation Therapy as They Progress to Metastatic Disease
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Includes: Supplementary data
Journal Articles

Pharmacokinetics, Safety, and Antitumor Effect of Apalutamide with Abiraterone Acetate plus Prednisone in Metastatic Castration-Resistant Prostate Cancer: Phase Ib Study

Edwin M. Posadas, Kim N. Chi, Ronald de Wit, Maja J.A. de Jonge, Gerhardt Attard, Terence W. Friedlander, Margaret K. Yu, Peter Hellemans, Caly Chien, Charlene Abrams, Juhui J. Jiao, Fred Saad
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (14): 3517–3524.
https://doi.org/10.1158/1078-0432.CCR-19-3402
Published: 15 July 2020
View article titled, Pharmacokinetics, Safety, and Antitumor Effect of Apalutamide with Abiraterone Acetate plus Prednisone in Metastatic Castration-Resistant Prostate Cancer: Phase Ib Study
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Includes: Supplementary data
Journal Articles

Serial Next-Generation Sequencing of Circulating Cell-Free DNA Evaluating Tumor Clone Response To Molecularly Targeted Drug Administration

Jean Sebastien Frenel, Suzanne Carreira, Jane Goodall, Desam Roda, Raquel Perez-Lopez, Nina Tunariu, Ruth Riisnaes, Susana Miranda, Ines Figueiredo, Daniel Nava-Rodrigues, Alan Smith, Christophe Leux, Isaac Garcia-Murillas, Roberta Ferraldeschi, David Lorente, Joaquin Mateo, Michael Ong, Timothy A. Yap, Udai Banerji, Delila Gasi Tandefelt, Nick Turner, Gerhardt Attard, Johann S. de Bono
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (20): 4586–4596.
https://doi.org/10.1158/1078-0432.CCR-15-0584
Published: 14 October 2015
View article titled, Serial Next-Generation Sequencing of Circulating Cell-Free DNA Evaluating Tumor Clone Response To Molecularly Targeted Drug Administration
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Includes: Supplementary data
Journal Articles

Improvements in Radiographic Progression-Free Survival Stratified by ERG Gene Status in Metastatic Castration-Resistant Prostate Cancer Patients Treated with Abiraterone Acetate

Gerhardt Attard, Johann S. de Bono, Christopher J. Logothetis, Karim Fizazi, Som D. Mukherjee, Anthony M. Joshua, Dirk Schrijvers, Alfons J.M. van den Eertwegh, Weimin Li, Arturo Molina, Thomas W. Griffin, Thian Kheoh, Deborah S. Ricci, Kathy Zelinsky, Dana E. Rathkopf, Howard I. Scher, Charles J. Ryan
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (7): 1621–1627.
https://doi.org/10.1158/1078-0432.CCR-14-1961
Published: 31 March 2015
View article titled, Improvements in Radiographic Progression-Free Survival Stratified by <em>ERG</em> Gene Status in Metastatic Castration-Resistant Prostate Cancer Patients Treated with Abiraterone Acetate
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Includes: Supplementary data
Journal Articles

Molecular Pathways: Inhibiting Steroid Biosynthesis in Prostate Cancer

Roberta Ferraldeschi, Nima Sharifi, Richard J. Auchus, Gerhardt Attard
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (13): 3353–3359.
https://doi.org/10.1158/1078-0432.CCR-12-0931
Published: 30 June 2013
View article titled, Molecular Pathways: Inhibiting Steroid Biosynthesis in Prostate Cancer
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Journal Articles

Baseline Circulating Tumor Cell Counts Significantly Enhance a Prognostic Score for Patients Participating in Phase I Oncology Trials

David Olmos, Richard D. Baird, Timothy A. Yap, Christophe Massard, Lorna Pope, Shahneen K. Sandhu, Gerhardt Attard, Juliet Dukes, Dionysis Papadatos-Pastos, Philippa Grainger, Stan B. Kaye, Johann S. de Bono
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (15): 5188–5196.
https://doi.org/10.1158/1078-0432.CCR-10-3019
Published: 31 July 2011
View article titled, Baseline Circulating Tumor Cell Counts Significantly Enhance a Prognostic Score for Patients Participating in Phase I Oncology Trials
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Includes: Supplementary data
Journal Articles

Translating Scientific Advancement into Clinical Benefit for Castration-Resistant Prostate Cancer Patients

Gerhardt Attard, Johann S. de Bono
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (12): 3867–3875.
https://doi.org/10.1158/1078-0432.CCR-11-0943
Published: 15 June 2011
View article titled, Translating Scientific Advancement into Clinical Benefit for Castration-Resistant Prostate Cancer Patients
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Journal Articles

Reporting the Capture Efficiency of a Filter-Based Microdevice: A CTC Is Not a CTC Unless It Is CD45 Negative—Letter

Gerhardt Attard, Mateus Crespo, Ai Chiin Lim, Lorna Pope, Andrea Zivi, Johann S. de Bono
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (9): 3048–3049.
https://doi.org/10.1158/1078-0432.CCR-10-3234
Published: 01 May 2011
View article titled, Reporting the Capture Efficiency of a Filter-Based Microdevice: A CTC Is Not a CTC Unless It Is CD45 Negative—Letter
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Journal Articles

New Strategies in Metastatic Prostate Cancer: Targeting the Androgen Receptor Signaling Pathway

Gerhardt Attard, Juliet Richards, Johann S. de Bono
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (7): 1649–1657.
https://doi.org/10.1158/1078-0432.CCR-10-0567
Published: 31 March 2011
View article titled, New Strategies in Metastatic Prostate Cancer: Targeting the Androgen Receptor Signaling Pathway
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Journal Articles

Studies of TMPRSS2-ERG Gene Fusions in Diagnostic Trans-Rectal Prostate Biopsies

Gerhardt Attard, Johann S. de Bono, Jeremy Clark, Colin S. Cooper
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (4): 1340.
https://doi.org/10.1158/1078-0432.CCR-09-2253
Published: 15 February 2010
View article titled, Studies of <em>TMPRSS2-ERG</em> Gene Fusions in Diagnostic Trans-Rectal Prostate Biopsies
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Journal Articles

A First-in-Man Phase I and Pharmacokinetic Study on CHR-2797 (Tosedostat), an Inhibitor of M1 Aminopeptidases, in Patients with Advanced Solid Tumors

Alison H.M. Reid, Andrew Protheroe, Gerhardt Attard, Nikki Hayward, Laura Vidal, James Spicer, Heather M. Shaw, Elizabeth A. Bone, Joanne Carter, Leon Hooftman, Adrian Harris, Johann S. De Bono
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (15): 4978–4985.
https://doi.org/10.1158/1078-0432.CCR-09-0306
Published: 29 July 2009
View article titled, A First-in-Man Phase I and Pharmacokinetic Study on CHR-2797 (Tosedostat), an Inhibitor of M1 Aminopeptidases, in Patients with Advanced Solid Tumors
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Journal Articles

Phase 1 and Pharmacokinetic Study of Lexatumumab in Patients with Advanced Cancers

Ruth Plummer, Gerhardt Attard, Simon Pacey, Louise Li, Albiruni Razak, Rebecca Perrett, Mary Barrett, Ian Judson, Stan Kaye, Norma Lynn Fox, Wendy Halpern, Alfred Corey, Hilary Calvert, Johann de Bono
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (20): 6187–6194.
https://doi.org/10.1158/1078-0432.CCR-07-0950
Published: 18 October 2007
View article titled, Phase 1 and Pharmacokinetic Study of Lexatumumab in Patients with Advanced Cancers
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Journal Articles

Potential Applications for Circulating Tumor Cells Expressing the Insulin-Like Growth Factor-I Receptor

Johann S. de Bono, Gerhardt Attard, Alex Adjei, Michael N. Pollak, Peter C. Fong, Paul Haluska, Luisa Roberts, Carrie Melvin, Madeline Repollet, David Chianese, Mark Connely, Leon W.M.M. Terstappen, Antonio Gualberto
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (12): 3611–3616.
https://doi.org/10.1158/1078-0432.CCR-07-0268
Published: 15 June 2007
View article titled, Potential Applications for Circulating Tumor Cells Expressing the Insulin-Like Growth Factor-I Receptor
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