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Journal Articles

Abstract A10: Redox regulation of the Wnt/β-catenin pathway in colorectal cancer

Alex Campos, Brian James, Petrus De Jong, Garth Powis
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (1_Supplement): A10.
https://doi.org/10.1158/1557-3265.PMCCAVULN16-A10
Published: 02 January 2017
View article titled, Abstract A10: Redox regulation of the Wnt/β-catenin pathway in colorectal cancer
Journal Articles

Hedgehog signaling and desmoplasia are regulated by hypoxia in pancreatic cancer

Taly Spivak-Kroizman, Galen Hostetter, Daniel Von Hoff, Richard Posner, Mena Abdelmelek, Brian James, Michael Demeure, Garth Powis
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (19_Supplement): PR11.
https://doi.org/10.1158/DIAG-10-PR11
Published: 15 August 2014
View article titled, Hedgehog signaling and desmoplasia are regulated by hypoxia in pancreatic cancer
Journal Articles

Resistance to BRAF Inhibition in BRAF-Mutant Colon Cancer Can Be Overcome with PI3K Inhibition or Demethylating Agents

Muling Mao, Feng Tian, John M. Mariadason, Chun C. Tsao, Robert Lemos, Jr, Farshid Dayyani, Y.N. Vashisht Gopal, Zhi-Qin Jiang, Ignacio I. Wistuba, Xi M. Tang, William G. Bornman, Gideon Bollag, Gordon B. Mills, Garth Powis, Jayesh Desai, Gary E. Gallick, Michael A. Davies, Scott Kopetz
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (3): 657–667.
https://doi.org/10.1158/1078-0432.CCR-11-1446
Published: 31 January 2013
View article titled, Resistance to BRAF Inhibition in BRAF-Mutant Colon Cancer Can Be Overcome with PI3K Inhibition or Demethylating Agents
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Includes: Supplementary data
Journal Articles

The Promise of Patient-Derived Xenografts: The Best Laid Plans of Mice and Men

Scott Kopetz, Robert Lemos, Garth Powis
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (19): 5160–5162.
https://doi.org/10.1158/1078-0432.CCR-12-2408
Published: 30 September 2012
View article titled, The Promise of Patient-Derived Xenografts: The Best Laid Plans of Mice and Men
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Includes: Supplementary data
Journal Articles

Inhibiting the Hypoxia Response for Cancer Therapy: The New Kid on the Block

Mei Yee Koh, Taly R. Spivak-Kroizman, Garth Powis
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (19): 5945–5946.
https://doi.org/10.1158/1078-0432.CCR-09-1650
Published: 30 September 2009
View article titled, Inhibiting the Hypoxia Response for Cancer Therapy: The New Kid on the Block
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Includes: Supplementary data
Journal Articles

The Antitumor Agent Imexon Activates Antioxidant Gene Expression: Evidence for an Oxidative Stress Response

Amanda F. Baker, Terry Landowski, Robert Dorr, Wendy R. Tate, Jaime M.C. Gard, Breonna E. Tavenner, Tomislov Dragovich, Amy Coon, Garth Powis
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (11): 3388–3394.
https://doi.org/10.1158/1078-0432.CCR-06-0873
Published: 01 June 2007
View article titled, The Antitumor Agent Imexon Activates Antioxidant Gene Expression: Evidence for an Oxidative Stress Response
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Journal Articles

Practicalities of Drugging the Phosphatidylinositol-3-Kinase/Akt Cell Survival Signaling Pathway

Garth Powis, Nathan Ihle, D. Lynn Kirkpatrick
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (10): 2964–2966.
https://doi.org/10.1158/1078-0432.CCR-06-0617
Published: 17 May 2006
View article titled, Practicalities of Drugging the Phosphatidylinositol-3-Kinase/Akt Cell Survival Signaling Pathway
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Journal Articles

Stability of Phosphoprotein as a Biological Marker of Tumor Signaling

Amanda F. Baker, Tomislav Dragovich, Nathan T. Ihle, Ryan Williams, Cecilia Fenoglio-Preiser, Garth Powis
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (12): 4338–4340.
https://doi.org/10.1158/1078-0432.CCR-05-0422
Published: 15 June 2005
View article titled, Stability of Phosphoprotein as a Biological Marker of Tumor Signaling
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Journal Articles

The Thioredoxin-1 Inhibitor 1-Methylpropyl 2-Imidazolyl Disulfide (PX-12) Decreases Vascular Permeability in Tumor Xenografts Monitored by Dynamic Contrast Enhanced Magnetic Resonance Imaging

Bénédicte F. Jordan, Matthew Runquist, Natarajan Raghunand, Robert J. Gillies, Wendy R. Tate, Garth Powis, Amanda F. Baker
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (2): 529–536.
https://doi.org/10.1158/1078-0432.529.11.2
Published: 08 February 2005
View article titled, The Thioredoxin-1 Inhibitor 1-Methylpropyl 2-Imidazolyl Disulfide (PX-12) Decreases Vascular Permeability in Tumor Xenografts Monitored by Dynamic Contrast Enhanced Magnetic Resonance Imaging
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Journal Articles

Thioredoxin Expression Is Associated with Lymph Node Status and Prognosis in Early Operable Non-Small Cell Lung Cancer

Stylianos Kakolyris, Alexandra Giatromanolaki, Michael Koukourakis, Garth Powis, John Souglakos, Efthimios Sivridis, Vassilis Georgoulias, Kevin C. Gatter, Adrian L. Harris
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (10): 3087–3091.
Published: 01 October 2001
View article titled, Thioredoxin Expression Is Associated with Lymph Node Status and Prognosis in Early Operable Non-Small Cell Lung Cancer
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