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Ganiraju C. Manyam
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Journal Articles

Multi-omics Analysis Reveals Immune Features Associated with Immunotherapy Benefit in Patients with Squamous Cell Lung Cancer from Phase III Lung-MAP S1400I Trial

Edwin Roger Parra, Jiexin Zhang, Dzifa Yawa Duose, Edgar Gonzalez-Kozlova, Mary W. Redman, Hong Chen, Ganiraju C. Manyam, Gayatri Kumar, Jianhua Zhang, Xingzhi Song, Rossana Lazcano, Mario L. Marques-Piubelli, Caddie Laberiano-Fernandez, Frank Rojas, Baili Zhang, Len Taing, Aashna Jhaveri, Jacob Geisberg, Jennifer Altreuter, Franziska Michor, James Provencher, Joyce Yu, Ethan Cerami, Radim Moravec, Kasthuri Kannan, Rajyalakshmi Luthra, Gheath Alatrash, Hsin-Hui Huang, Hui Xie, Manishkumar Patel, Kai Nie, Jocelyn Harris, Kimberly Argueta, James Lindsay, Roshni Biswas, Stephen Van Nostrand, Seunghee Kim-Schulze, Jhanelle E. Gray, Roy S. Herbst, Ignacio I. Wistuba, Scott Gettinger, Karen Kelly, Lyudmila Bazhenova, Sacha Gnjatic, J. Jack Lee, Jianjun Zhang, Cara Haymaker
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (8): 1655–1668.
https://doi.org/10.1158/1078-0432.CCR-23-0251
Published: 15 April 2024
View article titled, Multi-omics Analysis Reveals Immune Features Associated with Immunotherapy Benefit in Patients with Squamous Cell Lung Cancer from Phase III Lung-MAP S1400I Trial
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Includes: Supplementary data
Journal Articles

SPOP Mutations Target STING1 Signaling in Prostate Cancer and Create Therapeutic Vulnerabilities to PARP Inhibitor–Induced Growth Suppression

Chuandong Geng, Man-Chao Zhang, Ganiraju C. Manyam, Jody V. Vykoukal, Johannes F. Fahrmann, Shan Peng, Cheng Wu, Sanghee Park, Shakuntala Kondraganti, Daoqi Wang, Brian D. Robinson, Massimo Loda, Christopher E. Barbieri, Timothy A. Yap, Paul G. Corn, Samir Hanash, Bradley M. Broom, Patrick G. Pilié, Timothy C. Thompson
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (21): 4464–4478.
https://doi.org/10.1158/1078-0432.CCR-23-1439
Published: 01 November 2023
View article titled, SPOP Mutations Target STING1 Signaling in Prostate Cancer and Create Therapeutic Vulnerabilities to PARP Inhibitor–Induced Growth Suppression
Open the PDF for SPOP Mutations Target STING1 Signaling in Prostate Cancer and Create Therapeutic Vulnerabilities to PARP Inhibitor–Induced Growth Suppression in another window
Includes: Supplementary data
Journal Articles

ATR Inhibition Induces CDK1–SPOP Signaling and Enhances Anti–PD-L1 Cytotoxicity in Prostate Cancer

Zhe Tang, Patrick G. Pilié, Chuandong Geng, Ganiraju C. Manyam, Guang Yang, Sanghee Park, Daoqi Wang, Shan Peng, Cheng Wu, Guang Peng, Timothy A. Yap, Paul G. Corn, Bradley M. Broom, Timothy C. Thompson
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (17): 4898–4909.
https://doi.org/10.1158/1078-0432.CCR-21-1010
Published: 01 September 2021
View article titled, ATR Inhibition Induces CDK1–SPOP Signaling and Enhances Anti–PD-L1 Cytotoxicity in Prostate Cancer
Open the PDF for ATR Inhibition Induces CDK1–SPOP Signaling and Enhances Anti–PD-L1 Cytotoxicity in Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

ARID1A Mutation May Define an Immunologically Active Subgroup in Patients with Microsatellite Stable Colorectal Cancer

Amir Mehrvarz Sarshekeh, Jumanah Alshenaifi, Jason Roszik, Ganiraju C. Manyam, Shailesh M. Advani, Riham Katkhuda, Anuj Verma, Michael Lam, Jason Willis, John Paul Shen, Jeffrey Morris, Jennifer S. Davis, Jonathan M. Loree, Hey Min Lee, Jaffer A. Ajani, Dipen M. Maru, Michael J. Overman, Scott Kopetz
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (6): 1663–1670.
https://doi.org/10.1158/1078-0432.CCR-20-2404
Published: 15 March 2021
View article titled, ARID1A Mutation May Define an Immunologically Active Subgroup in Patients with Microsatellite Stable Colorectal Cancer
Open the PDF for ARID1A Mutation May Define an Immunologically Active Subgroup in Patients with Microsatellite Stable Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

The MD Anderson Prostate Cancer Patient-derived Xenograft Series (MDA PCa PDX) Captures the Molecular Landscape of Prostate Cancer and Facilitates Marker-driven Therapy Development

Nallasivam Palanisamy, Jun Yang, Peter D.A. Shepherd, Elsa M. Li-Ning-Tapia, Estefania Labanca, Ganiraju C. Manyam, Murali K. Ravoori, Vikas Kundra, John C. Araujo, Eleni Efstathiou, Louis L. Pisters, Xinhai Wan, Xuemei Wang, Elba S. Vazquez, Ana M. Aparicio, Shannon L. Carskadon, Scott A. Tomlins, Lakshmi P. Kunju, Arul M. Chinnaiyan, Bradley M. Broom, Christopher J. Logothetis, Patricia Troncoso, Nora M. Navone
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (18): 4933–4946.
https://doi.org/10.1158/1078-0432.CCR-20-0479
Published: 15 September 2020
View article titled, The MD Anderson Prostate Cancer Patient-derived Xenograft Series (MDA PCa PDX) Captures the Molecular Landscape of Prostate Cancer and Facilitates Marker-driven Therapy Development
Open the PDF for The MD Anderson Prostate Cancer Patient-derived Xenograft Series (MDA PCa PDX) Captures the Molecular Landscape of Prostate Cancer and Facilitates Marker-driven Therapy Development in another window
Includes: Supplementary data
Journal Articles

PARP Inhibition Suppresses GR–MYCN–CDK5–RB1–E2F1 Signaling and Neuroendocrine Differentiation in Castration-Resistant Prostate Cancer

Bo Liu, Likun Li, Guang Yang, Chuandong Geng, Yong Luo, Wenhui Wu, Ganiraju C. Manyam, Dimitrios Korentzelos, Sanghee Park, Zhe Tang, Cheng Wu, Zhenyang Dong, Michael Sigouros, Andrea Sboner, Himisha Beltran, Yu Chen, Paul G. Corn, Michael T. Tetzlaff, Patricia Troncoso, Bradley Broom, Timothy C. Thompson
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (22): 6839–6851.
https://doi.org/10.1158/1078-0432.CCR-19-0317
Published: 15 November 2019
View article titled, PARP Inhibition Suppresses GR–MYCN–CDK5–RB1–E2F1 Signaling and Neuroendocrine Differentiation in Castration-Resistant Prostate Cancer
Open the PDF for PARP Inhibition Suppresses GR–MYCN–CDK5–RB1–E2F1 Signaling and Neuroendocrine Differentiation in Castration-Resistant Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Clinical and Biologic Significance of MYC Genetic Mutations in De Novo Diffuse Large B-cell Lymphoma

Zijun Y. Xu-Monette, Qipan Deng, Ganiraju C. Manyam, Alexander Tzankov, Ling Li, Yi Xia, Xiao-xiao Wang, Dehui Zou, Carlo Visco, Karen Dybkær, Jun Li, Li Zhang, Han Liang, Santiago Montes-Moreno, April Chiu, Attilio Orazi, Youli Zu, Govind Bhagat, Kristy L. Richards, Eric D. Hsi, William W.L. Choi, J. Han van Krieken, Jooryung Huh, Maurilio Ponzoni, Andrés J.M. Ferreri, Ben M. Parsons, Michael B. Møller, Sa A. Wang, Roberto N. Miranda, Miguel A. Piris, Jane N. Winter, L. Jeffrey Medeiros, Yong Li, Ken H. Young
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (14): 3593–3605.
https://doi.org/10.1158/1078-0432.CCR-15-2296
Published: 14 July 2016
View article titled, Clinical and Biologic Significance of <em>MYC</em> Genetic Mutations in <em>De Novo</em> Diffuse Large B-cell Lymphoma
Open the PDF for Clinical and Biologic Significance of <em>MYC</em> Genetic Mutations in <em>De Novo</em> Diffuse Large B-cell Lymphoma in another window
Includes: Supplementary data
Journal Articles

Clinical Implications of Phosphorylated STAT3 Expression in De Novo Diffuse Large B-cell Lymphoma

Chi Young Ok, Jiayu Chen, Zijun Y. Xu-Monette, Alexandar Tzankov, Ganiraju C. Manyam, Ling Li, Carlo Visco, Santiago Montes-Moreno, Karen Dybkær, April Chiu, Attilio Orazi, Youli Zu, Govind Bhagat, Kristy L. Richards, Eric D. Hsi, William W.L. Choi, J. Han van Krieken, Jooryung Huh, Xiaoying Zhao, Maurilio Ponzoni, Andrés J.M. Ferreri, Francesco Bertoni, John P. Farnen, Michael B. Møller, Miguel A. Piris, Jane N. Winter, L. Jeffrey Medeiros, Ken H. Young
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (19): 5113–5123.
https://doi.org/10.1158/1078-0432.CCR-14-0683
Published: 30 September 2014
View article titled, Clinical Implications of Phosphorylated STAT3 Expression in <em>De Novo</em> Diffuse Large B-cell Lymphoma
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Includes: Supplementary data
Journal Articles

Prevalence and Clinical Implications of Epstein–Barr Virus Infection in De Novo Diffuse Large B-Cell Lymphoma in Western Countries

Chi Young Ok, Ling Li, Zijun Y. Xu-Monette, Carlo Visco, Alexander Tzankov, Ganiraju C. Manyam, Santiago Montes-Moreno, Karen Dybaer, April Chiu, Attilio Orazi, Youli Zu, Govind Bhagat, Jiayu Chen, Kristy L. Richards, Eric D. Hsi, William W. L. Choi, J. Han van Krieken, Jooryung Huh, Weiyun Ai, Maurilio Ponzoni, Andrés J.M. Ferreri, John P. Farnen, Michael B. Møller, Carlo E. Bueso-Ramos, Roberto N. Miranda, Jane N. Winter, Miguel A. Piris, L. Jeffrey Medeiros, Ken H. Young
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (9): 2338–2349.
https://doi.org/10.1158/1078-0432.CCR-13-3157
Published: 30 April 2014
View article titled, Prevalence and Clinical Implications of Epstein–Barr Virus Infection in <em>De Novo</em> Diffuse Large B-Cell Lymphoma in Western Countries
Open the PDF for Prevalence and Clinical Implications of Epstein–Barr Virus Infection in <em>De Novo</em> Diffuse Large B-Cell Lymphoma in Western Countries in another window
Includes: Supplementary data