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Journal Articles

Genomic Profiling to Contextualize the Results of Intervention for Smoldering Multiple Myeloma

Dickran Kazandjian, Benjamin Diamond, Marios Papadimitriou, Elizabeth Hill, Romanos Sklavenitis-Pistofidis, Bachisio Ziccheddu, Patrick Blaney, Monika Chojnacka, Michael Durante, Kylee Maclachlan, Ryan Young, Saad Usmani, Faith Davies, Gad Getz, Irene Ghobrial, Neha Korde, Gareth Morgan, Francesco Maura, Ola Landgren
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (19): 4482–4490.
https://doi.org/10.1158/1078-0432.CCR-24-0210
Published: 01 October 2024
View article titled, Genomic Profiling to Contextualize the Results of Intervention for Smoldering Multiple Myeloma
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Includes: Supplementary data
Journal Articles

Efficacy of Nivolumab in Pediatric Cancers with High Mutation Burden and Mismatch Repair Deficiency

Anirban Das, Uri Tabori, Lauren C. Sambira Nahum, Natalie B. Collins, Rebecca Deyell, Rina Dvir, Cecile Faure-Conter, Timothy E. Hassall, Jane E. Minturn, Melissa Edwards, Elissa Brookes, Vanessa Bianchi, Adrian Levine, Simone C. Stone, Sumedha Sudhaman, Santiago Sanchez Ramirez, Ayse B. Ercan, Lucie Stengs, Jill Chung, Logine Negm, Gad Getz, Yosef E. Maruvka, Birgit Ertl-Wagner, Pamela S. Ohashi, Trevor Pugh, Cynthia Hawkins, Eric Bouffet, Daniel A. Morgenstern
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (23): 4770–4783.
https://doi.org/10.1158/1078-0432.CCR-23-0411
Published: 01 December 2023
View article titled, Efficacy of Nivolumab in Pediatric Cancers with High Mutation Burden and Mismatch Repair Deficiency
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Includes: Supplementary data
Journal Articles

Clinical Importance of the lncRNA NEAT1 in Cancer Patients Treated with Immune Checkpoint Inhibitors

Joseph Toker, J. Bryan Iorgulescu, Alexander L. Ling, Genaro R. Villa, Josephina A.M.A. Gadet, Laxmi Parida, Gad Getz, Catherine J. Wu, David A. Reardon, E. Antonio Chiocca, Marco Mineo
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (12): 2226–2238.
https://doi.org/10.1158/1078-0432.CCR-22-3714
Published: 13 June 2023
View article titled, Clinical Importance of the lncRNA <em>NEAT1</em> in Cancer Patients Treated with Immune Checkpoint Inhibitors
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Includes: Supplementary data
Journal Articles

Clinical Efficacy and Whole-Exome Sequencing of Liquid Biopsies in a Phase IB/II Study of Bazedoxifene and Palbociclib in Advanced Hormone Receptor–Positive Breast Cancer

Junko Tsuji, Tianyu Li, Albert Grinshpun, Tim Coorens, Douglas Russo, Leilani Anderson, Rebecca Rees, Agostina Nardone, Candace Patterson, Niall J. Lennon, Carrie Cibulskis, Ignaty Leshchiner, Nabihah Tayob, Sara M. Tolaney, Nadine Tung, Donald P. McDonnell, Ian E. Krop, Eric P. Winer, Chip Stewart, Gad Getz, Rinath Jeselsohn
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (23): 5066–5078.
https://doi.org/10.1158/1078-0432.CCR-22-2305
Published: 01 December 2022
View article titled, Clinical Efficacy and Whole-Exome Sequencing of Liquid Biopsies in a Phase IB/II Study of Bazedoxifene and Palbociclib in Advanced Hormone Receptor–Positive Breast Cancer
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Includes: Supplementary data
Journal Articles

Abstract PO-055: Molecular characterization of papillary thyroid cancer in relation to ionizing radiation dose following the Chernobyl accident

Lindsay M. Morton, Danielle Karyadi, Chip Stewart, Tetiana Bogdanova, Eric Dawson, Mia Steinberg, Jieqiong Dai, Stephen Hartley, Sara Schonfeld, Joshua Sampson, Yosi Maruvka, Vidushi Kapoor, Dale Ramsden, Juan Carvajal-Garcia, Chuck Perou, Joel Parker, Marko Krznaric, Meredith Yeager, Joseph Boland, Amy Hutchinson, Belynda Hicks, Casey Dagnall, Julie Gastier-Foster, Jay Bowen, Olivia Lee, Mitchell Machiela, Elizabeth Cahoon, Alina Brenner, Kiyohiko Mabuchi, Vladimir Drozdovitch, Sergii Masiuk, Mykola Chepurny, Liudmyla Yu Zurnadzhy, Maureen Hatch, Amy Berrington de Gonzalez, Gerry Thomas, Mykola Tronko, Gad Getz, Stephen Chanock
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (8_Supplement): PO-055.
https://doi.org/10.1158/1557-3265.RADSCI21-PO-055
Published: 15 April 2021
View article titled, Abstract PO-055: Molecular characterization of papillary thyroid cancer in relation to ionizing radiation dose following the Chernobyl accident
Journal Articles

Abstract PO-051: Radiation therapy enhances the presentation of phosphopeptides by MHC-I on cancer cells

Samantha J. Van Nest, Tomer M. Yaron, Martin G. Klatt, Noah E. Dephoure, Gad Getz, Laura Santambrogio, Olivier Elemento, David Scheinberg, Sandra Demaria, Lewis C. Cantley
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (8_Supplement): PO-051.
https://doi.org/10.1158/1557-3265.RADSCI21-PO-051
Published: 15 April 2021
View article titled, Abstract PO-051: Radiation therapy enhances the presentation of phosphopeptides by MHC-I on cancer cells
Journal Articles

Identification of Somatically Acquired BRCA1/2 Mutations by cfDNA Analysis in Patients with Metastatic Breast Cancer

Neelima Vidula, Taronish Dubash, Michael S. Lawrence, Antoine Simoneau, Andrzej Niemierko, Erica Blouch, Becky Nagy, Whijae Roh, Brian Chirn, Brittany A. Reeves, Giuliana Malvarosa, Jochen Lennerz, Steven J. Isakoff, Dejan Juric, Douglas Micalizzi, Seth Wander, Laura Spring, Beverly Moy, Kristen Shannon, Jerry Younger, Richard Lanman, Mehmet Toner, A. John Iafrate, Gad Getz, Lee Zou, Leif W. Ellisen, Shyamala Maheswaran, Daniel A. Haber, Aditya Bardia
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (18): 4852–4862.
https://doi.org/10.1158/1078-0432.CCR-20-0638
Published: 15 September 2020
View article titled, Identification of Somatically Acquired <em>BRCA1/2</em> Mutations by cfDNA Analysis in Patients with Metastatic Breast Cancer
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Includes: Supplementary data
Journal Articles

Abstract A04: Tumor development trajectories for exploring differences between cancer subtypes

Ignaty Leshchiner, Daniel Rosebrock, Oliver Spiro, Edmund Mroz, Dimitri Livitz, James W. Rocco, Gad Getz
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (12_Supplement_2): A04.
https://doi.org/10.1158/1557-3265.AACRAHNS19-A04
Published: 15 June 2020
View article titled, Abstract A04: Tumor development trajectories for exploring differences between cancer subtypes
Journal Articles

Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer

Heather A. Parsons, Justin Rhoades, Sarah C. Reed, Gregory Gydush, Priyanka Ram, Pedro Exman, Kan Xiong, Christopher C. Lo, Tianyu Li, Mark Fleharty, Gregory J. Kirkner, Denisse Rotem, Ofir Cohen, Fangyan Yu, Mariana Fitarelli-Kiehl, Ka Wai Leong, Melissa E. Hughes, Shoshana M. Rosenberg, Laura C. Collins, Kathy D. Miller, Brendan Blumenstiel, Lorenzo Trippa, Carrie Cibulskis, Donna S. Neuberg, Matthew DeFelice, Samuel S. Freeman, Niall J. Lennon, Nikhil Wagle, Gavin Ha, Daniel G. Stover, Atish D. Choudhury, Gad Getz, Eric P. Winer, Matthew Meyerson, Nancy U. Lin, Ian Krop, J. Christopher Love, G. Mike Makrigiorgos, Ann H. Partridge, Erica L. Mayer, Todd R. Golub, Viktor A. Adalsteinsson
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (11): 2556–2564.
https://doi.org/10.1158/1078-0432.CCR-19-3005
Published: 01 June 2020
View article titled, Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer
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Includes: Supplementary data
Journal Articles

Genomic Evolutionary Patterns of Leiomyosarcoma and Liposarcoma

Ali Amin-Mansour, Suzanne George, Stefano Sioletic, Scott L. Carter, Mara Rosenberg, Amaro Taylor-Weiner, Chip Stewart, Aaron Chevalier, Sara Seepo, Adam Tracy, Gad Getz, Jason L. Hornick, Marisa R. Nucci, Bradley Quade, George D. Demetri, Chandrajit P. Raut, Levi A. Garraway, Eliezer M. Van Allen, Andrew J. Wagner
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (16): 5135–5142.
https://doi.org/10.1158/1078-0432.CCR-19-0271
Published: 15 August 2019
View article titled, Genomic Evolutionary Patterns of Leiomyosarcoma and Liposarcoma
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Includes: Supplementary data
Journal Articles

Genomic Evolution after Chemoradiotherapy in Anal Squamous Cell Carcinoma

Kent W. Mouw, James M. Cleary, Brendan Reardon, Jonathan Pike, Lior Z. Braunstein, Jaegil Kim, Ali Amin-Mansour, Diana Miao, Alexis Damish, Joanna Chin, Patrick A. Ott, Charles S. Fuchs, Neil E. Martin, Gad Getz, Scott Carter, Harvey J. Mamon, Jason L. Hornick, Eliezer M. Van Allen, Alan D. D'Andrea
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (12): 3214–3222.
https://doi.org/10.1158/1078-0432.CCR-16-2017
Published: 14 June 2017
View article titled, Genomic Evolution after Chemoradiotherapy in Anal Squamous Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Survival of Del17p CLL Depends on Genomic Complexity and Somatic Mutation

Lijian Yu, Haesook T. Kim, Siddha N. Kasar, Parul Benien, Wei Du, Kevin Hoang, Andrew Aw, Bethany Tesar, Reina Improgo, Stacey M. Fernandes, Saranya Radhakrishnan, Josephine L. Klitgaard, Charles Lee, Gad Getz, Sunita R. Setlur, Jennifer R. Brown
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (3): 735–745.
https://doi.org/10.1158/1078-0432.CCR-16-0594
Published: 31 January 2017
View article titled, Survival of Del17p CLL Depends on Genomic Complexity and Somatic Mutation
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Includes: Supplementary data
Journal Articles

Abstract PR4: Integrative analysis of genomic and pharmacologic data from the Cancer Cell Line Encyclopedia

Nicolas Stransky, Kavitha Venkatesan, Jordi Barretina, Giordano Caponigro, Adam Margolin, Michael Morrissey, Pichai Raman, Gad Getz, Michael Berger, Cory Johannessen, Adam Callahan, Paula Morais, Scott Mahan, Supriya Gupta, Robert Onofrio, Carrie Sougnez, Wendy Winckler, Lili Niu, Sarah Kehoe, Charles Hatton, Ted Liefeld, Dmitriy Sonkin, Michael Jones, Christopher Wilson, Sungjoon Kim, Jianwei Che, Andrew Su, Laura MacConaill, Stacey Gabriel, Kristin Ardlie, Michael Reich, Jill Mesirov, Markus Warmuth, Barbara Weber, Matthew Meyerson, Todd Golub, Jessica Harris, William Sellers, Robert Schlegel, Levi Garraway
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (14_Supplement): PR4.
https://doi.org/10.1158/1078-0432.TCMUSA10-PR4
Published: 02 February 2016
View article titled, Abstract PR4: Integrative analysis of genomic and pharmacologic data from the Cancer Cell Line Encyclopedia
Journal Articles

Invasive Bladder Cancer: Genomic Insights and Therapeutic Promise

Jaegil Kim, Rehan Akbani, Chad J. Creighton, Seth P. Lerner, John N. Weinstein, Gad Getz, David J. Kwiatkowski
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (20): 4514–4524.
https://doi.org/10.1158/1078-0432.CCR-14-1215
Published: 14 October 2015
View article titled, Invasive Bladder Cancer: Genomic Insights and Therapeutic Promise
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Journal Articles

Integrative and Comparative Genomic Analysis of HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinomas

Tanguy Y. Seiwert, Zhixiang Zuo, Michaela K. Keck, Arun Khattri, Chandra S. Pedamallu, Thomas Stricker, Christopher Brown, Trevor J. Pugh, Petar Stojanov, Juok Cho, Michael S. Lawrence, Gad Getz, Johannes Brägelmann, Rebecca DeBoer, Ralph R. Weichselbaum, Alexander Langerman, Louis Portugal, Elizabeth Blair, Kerstin Stenson, Mark W. Lingen, Ezra E.W. Cohen, Everett E. Vokes, Kevin P. White, Peter S. Hammerman
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (3): 632–641.
https://doi.org/10.1158/1078-0432.CCR-13-3310
Published: 01 February 2015
View article titled, Integrative and Comparative Genomic Analysis of HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinomas
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Includes: Supplementary data
Journal Articles

Resistance to CDK2 Inhibitors Is Associated with Selection of Polyploid Cells in CCNE1-Amplified Ovarian Cancer

Dariush Etemadmoghadam, George Au-Yeung, Meaghan Wall, Chris Mitchell, Maya Kansara, Elizabeth Loehrer, Crisoula Batzios, Joshy George, Sarah Ftouni, Barbara A. Weir, Scott Carter, Irma Gresshoff, Linda Mileshkin, Danny Rischin, William C. Hahn, Paul M. Waring, Gad Getz, Carleen Cullinane, Lynda J. Campbell, David D. Bowtell
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (21): 5960–5971.
https://doi.org/10.1158/1078-0432.CCR-13-1337
Published: 31 October 2013
View article titled, Resistance to CDK2 Inhibitors Is Associated with Selection of Polyploid Cells in <em>CCNE1</em>-Amplified Ovarian Cancer
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Includes: Supplementary data
Journal Articles

Abstract PR1: Integrating expression data improves mutational significance analysis of lung squamous carcinoma

Bryan Hernandez, Peter Hammerman, Marcin Imielinski, Michael Lawrence, Petar Stojanov, Gad Getz, Matthew Meyerson
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (3_Supplement): PR1.
https://doi.org/10.1158/1078-0432.12AACRIASLC-PR1
Published: 01 February 2012
View article titled, Abstract PR1: Integrating expression data improves mutational significance analysis of lung squamous carcinoma
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Journal Articles

Abstract B13: FGFR2 as a therapeutic target in squamous cell lung carcinoma

Rachel G. Liao, Peter Hammerman, Andrey Sivachencko, Heidi Greulich, Gad Getz, Qingsong Liu, Nathanael Gray, Matthew Meyerson
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (3_Supplement): B13.
https://doi.org/10.1158/1078-0432.12AACRIASLC-B13
Published: 01 February 2012
View article titled, Abstract B13: FGFR2 as a therapeutic target in squamous cell lung carcinoma
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Journal Articles

Integrated Genome-Wide DNA Copy Number and Expression Analysis Identifies Distinct Mechanisms of Primary Chemoresistance in Ovarian Carcinomas

Dariush Etemadmoghadam, Anna deFazio, Rameen Beroukhim, Craig Mermel, Joshy George, Gad Getz, Richard Tothill, Aikou Okamoto, Maria B. Raeder, AOCS Study Group, Paul Harnett, Stephen Lade, Lars A. Akslen, Anna V. Tinker, Bianca Locandro, Kathryn Alsop, Yoke-Eng Chiew, Nadia Traficante, Sian Fereday, Daryl Johnson, Stephen Fox, William Sellers, Mitsuyoshi Urashima, Helga B. Salvesen, Matthew Meyerson, David Bowtell
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (4): 1417–1427.
https://doi.org/10.1158/1078-0432.CCR-08-1564
Published: 19 February 2009
View article titled, Integrated Genome-Wide DNA Copy Number and Expression Analysis Identifies Distinct Mechanisms of Primary Chemoresistance in Ovarian Carcinomas
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Includes: Supplementary data