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Gabriela Alexe
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Journal Articles

High-throughput Chemical Screening Identifies Focal Adhesion Kinase and Aurora Kinase B Inhibition as a Synergistic Treatment Combination in Ewing Sarcoma

Sarah Wang, Elizabeth E. Hwang, Rajarshi Guha, Allison F. O'Neill, Nicole Melong, Chansey J. Veinotte, Amy Conway Saur, Kellsey Wuerthele, Min Shen, Crystal McKnight, Gabriela Alexe, Madeleine E. Lemieux, Amy Wang, Emma Hughes, Xin Xu, Matthew B. Boxer, Matthew D. Hall, Andrew Kung, Jason N. Berman, Mindy I. Davis, Kimberly Stegmaier, Brian D. Crompton
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (14): 4552–4566.
https://doi.org/10.1158/1078-0432.CCR-17-0375
Published: 15 July 2019
View article titled, High-throughput Chemical Screening Identifies Focal Adhesion Kinase and Aurora Kinase B Inhibition as a Synergistic Treatment Combination in Ewing Sarcoma
Open the PDF for High-throughput Chemical Screening Identifies Focal Adhesion Kinase and Aurora Kinase B Inhibition as a Synergistic Treatment Combination in Ewing Sarcoma in another window
Includes: Supplementary data
Journal Articles

A Combination CDK4/6 and IGF1R Inhibitor Strategy for Ewing Sarcoma

Lillian M. Guenther, Neekesh V. Dharia, Linda Ross, Amy Conway, Amanda L. Robichaud, Jerrel L. Catlett, II, Caroline S. Wechsler, Elizabeth S. Frank, Amy Goodale, Alanna J. Church, Yuen-Yi Tseng, Rajarshi Guha, Crystal G. McKnight, Katherine A. Janeway, Jesse S. Boehm, Jaume Mora, Mindy I. Davis, Gabriela Alexe, Federica Piccioni, Kimberly Stegmaier
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (4): 1343–1357.
https://doi.org/10.1158/1078-0432.CCR-18-0372
Published: 15 February 2019
View article titled, A Combination CDK4/6 and IGF1R Inhibitor Strategy for Ewing Sarcoma
Open the PDF for A Combination CDK4/6 and IGF1R Inhibitor Strategy for Ewing Sarcoma in another window
Includes: Supplementary data
Journal Articles

Synergistic Drug Combinations with a CDK4/6 Inhibitor in T-cell Acute Lymphoblastic Leukemia

Yana Pikman, Gabriela Alexe, Giovanni Roti, Amy Saur Conway, Andrew Furman, Emily S. Lee, Andrew E. Place, Sunkyu Kim, Chitra Saran, Rebecca Modiste, David M. Weinstock, Marian Harris, Andrew L. Kung, Lewis B. Silverman, Kimberly Stegmaier
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (4): 1012–1024.
https://doi.org/10.1158/1078-0432.CCR-15-2869
Published: 14 February 2017
View article titled, Synergistic Drug Combinations with a CDK4/6 Inhibitor in T-cell Acute Lymphoblastic Leukemia
Open the PDF for Synergistic Drug Combinations with a CDK4/6 Inhibitor in T-cell Acute Lymphoblastic Leukemia in another window
Includes: Supplementary data
Journal Articles

NF-κB activation in basal and HER2+ breast cancers occurs via different mechanisms

Vasisht Tadigotla, Gabriela Alexe, Stefano Monti, Pablo Tamayo, Nilay Sethi, Gyan Bhanot, Shridhar Ganesan, Charles DeLisi
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (15_Supplement): A35.
Published: 15 August 2014
View article titled, NF-κB activation in basal and HER2+ breast cancers occurs via different mechanisms