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Gaël Roué
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Journal Articles

Antitumor Activity of the Novel BTK Inhibitor TG-1701 Is Associated with Disruption of Ikaros Signaling in Patients with B-cell Non–Hodgkin Lymphoma

Marcelo Lima Ribeiro, Diana Reyes-Garau, Meritxell Vinyoles, Núria Profitós Pelejà, Juliana Carvalho Santos, Marc Armengol, Miranda Fernández-Serrano, Alícia Sedó Mor, Joan J. Bech-Serra, Pedro Blecua, Eva Musulen, Carolina De La Torre, Hari Miskin, Manel Esteller, Francesc Bosch, Pablo Menéndez, Emmanuel Normant, Gaël Roué
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (23): 6591–6601.
https://doi.org/10.1158/1078-0432.CCR-21-1067
Published: 01 December 2021
View article titled, Antitumor Activity of the Novel BTK Inhibitor TG-1701 Is Associated with Disruption of Ikaros Signaling in Patients with B-cell Non–Hodgkin Lymphoma
Open the PDF for Antitumor Activity of the Novel BTK Inhibitor TG-1701 Is Associated with Disruption of Ikaros Signaling in Patients with B-cell Non–Hodgkin Lymphoma in another window
Includes: Supplementary data
Journal Articles

The Human CD38 Monoclonal Antibody Daratumumab Shows Antitumor Activity and Hampers Leukemia–Microenvironment Interactions in Chronic Lymphocytic Leukemia

Alba Matas-Céspedes, Anna Vidal-Crespo, Vanina Rodriguez, Neus Villamor, Julio Delgado, Eva Giné, Heleia Roca-Ho, Pablo Menéndez, Elías Campo, Armando López-Guillermo, Dolors Colomer, Gaël Roué, Adrian Wiestner, Paul W.H.I. Parren, Parul Doshi, Jeroen Lammerts van Bueren, Patricia Pérez-Galán
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (6): 1493–1505.
https://doi.org/10.1158/1078-0432.CCR-15-2095
Published: 14 March 2017
View article titled, The Human CD38 Monoclonal Antibody Daratumumab Shows Antitumor Activity and Hampers Leukemia–Microenvironment Interactions in Chronic Lymphocytic Leukemia
Open the PDF for The Human CD38 Monoclonal Antibody Daratumumab Shows Antitumor Activity and Hampers Leukemia–Microenvironment Interactions in Chronic Lymphocytic Leukemia in another window
Includes: Supplementary data
Journal Articles

Disruption of Follicular Dendritic Cells–Follicular Lymphoma Cross-talk by the Pan-PI3K Inhibitor BKM120 (Buparlisib)

Alba Matas-Céspedes, Vanina Rodriguez, Susana G. Kalko, Anna Vidal-Crespo, Laia Rosich, Teresa Casserras, Patricia Balsas, Neus Villamor, Eva Giné, Elías Campo, Gaël Roué, Armando López-Guillermo, Dolors Colomer, Patricia Pérez-Galán
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (13): 3458–3471.
https://doi.org/10.1158/1078-0432.CCR-14-0154
Published: 30 June 2014
View article titled, Disruption of Follicular Dendritic Cells–Follicular Lymphoma Cross-talk by the Pan-PI3K Inhibitor BKM120 (Buparlisib)
Open the PDF for Disruption of Follicular Dendritic Cells–Follicular Lymphoma Cross-talk by the Pan-PI3K Inhibitor BKM120 (Buparlisib) in another window
Includes: Supplementary data
Journal Articles

Antitumoral Activity of Lenalidomide in In Vitro and In Vivo Models of Mantle Cell Lymphoma Involves the Destabilization of Cyclin D1/p27KIP1 Complexes

Alexandra Moros, Sophie Bustany, Julie Cahu, Ifigènia Saborit-Villarroya, Antonio Martínez, Dolors Colomer, Brigitte Sola, Gaël Roué
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (2): 393–403.
https://doi.org/10.1158/1078-0432.CCR-13-1569
Published: 16 January 2014
View article titled, Antitumoral Activity of Lenalidomide in <em>In Vitro</em> and <em>In Vivo</em> Models of Mantle Cell Lymphoma Involves the Destabilization of Cyclin D1/p27<sup>KIP1</sup> Complexes
Open the PDF for Antitumoral Activity of Lenalidomide in <em>In Vitro</em> and <em>In Vivo</em> Models of Mantle Cell Lymphoma Involves the Destabilization of Cyclin D1/p27<sup>KIP1</sup> Complexes in another window
Includes: Supplementary data
Journal Articles

Sorafenib Inhibits Cell Migration and Stroma-Mediated Bortezomib Resistance by Interfering B-cell Receptor Signaling and Protein Translation in Mantle Cell Lymphoma

Sílvia Xargay-Torrent, Mónica López-Guerra, Arnau Montraveta, Ifigènia Saborit-Villarroya, Laia Rosich, Alba Navarro, Patricia Pérez-Galán, Gaël Roué, Elias Campo, Dolors Colomer
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (3): 586–597.
https://doi.org/10.1158/1078-0432.CCR-12-1935
Published: 31 January 2013
View article titled, Sorafenib Inhibits Cell Migration and Stroma-Mediated Bortezomib Resistance by Interfering B-cell Receptor Signaling and Protein Translation in Mantle Cell Lymphoma
Open the PDF for Sorafenib Inhibits Cell Migration and Stroma-Mediated Bortezomib Resistance by Interfering B-cell Receptor Signaling and Protein Translation in Mantle Cell Lymphoma in another window
Journal Articles

Counteracting Autophagy Overcomes Resistance to Everolimus in Mantle Cell Lymphoma

Laia Rosich, Sílvia Xargay-Torrent, Mónica López-Guerra, Elías Campo, Dolors Colomer, Gaël Roué
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (19): 5278–5289.
https://doi.org/10.1158/1078-0432.CCR-12-0351
Published: 30 September 2012
View article titled, Counteracting Autophagy Overcomes Resistance to Everolimus in Mantle Cell Lymphoma
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Includes: Supplementary data
Journal Articles

Vorinostat-Induced Apoptosis in Mantle Cell Lymphoma Is Mediated by Acetylation of Proapoptotic BH3-Only Gene Promoters

Sílvia Xargay-Torrent, Mónica López-Guerra, Ifigènia Saborit-Villarroya, Laia Rosich, Elias Campo, Gaël Roué, Dolors Colomer
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (12): 3956–3968.
https://doi.org/10.1158/1078-0432.CCR-10-3412
Published: 15 June 2011
View article titled, Vorinostat-Induced Apoptosis in Mantle Cell Lymphoma Is Mediated by Acetylation of Proapoptotic BH3-Only Gene Promoters
Open the PDF for Vorinostat-Induced Apoptosis in Mantle Cell Lymphoma Is Mediated by Acetylation of Proapoptotic BH3-Only Gene Promoters in another window
Journal Articles

In vitro and In vivo Selective Antitumor Activity of Edelfosine against Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia Involving Lipid Rafts

Faustino Mollinedo, Janis de la Iglesia-Vicente, Consuelo Gajate, Ander Estella-Hermoso de Mendoza, Janny A. Villa-Pulgarin, Mercè de Frias, Gaël Roué, Joan Gil, Dolors Colomer, Miguel A. Campanero, Maria J. Blanco-Prieto
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (7): 2046–2054.
https://doi.org/10.1158/1078-0432.CCR-09-2456
Published: 31 March 2010
View article titled, <em>In vitro</em> and <em>In vivo</em> Selective Antitumor Activity of Edelfosine against Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia Involving Lipid Rafts
Open the PDF for <em>In vitro</em> and <em>In vivo</em> Selective Antitumor Activity of Edelfosine against Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia Involving Lipid Rafts in another window
Includes: Supplementary data