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Freda K. Stevenson
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Journal Articles

Preclinical Evaluation of a Novel SHIP1 Phosphatase Activator for Inhibition of PI3K Signaling in Malignant B Cells

Elizabeth A. Lemm, Beatriz Valle-Argos, Lindsay D. Smith, Johanna Richter, Yohannes Gebreselassie, Matthew J. Carter, Jana Karolova, Michael Svaton, Karel Helman, Nicola J. Weston-Bell, Laura Karydis, Chris T. Williamson, Georg Lenz, Jeremy Pettigrew, Curtis Harwig, Freda K. Stevenson, Mark Cragg, Francesco Forconi, Andrew J. Steele, Jennifer Cross, Lloyd Mackenzie, Pavel Klener, Graham Packham
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (7): 1700–1711.
https://doi.org/10.1158/1078-0432.CCR-19-2202
Published: 01 April 2020
View article titled, Preclinical Evaluation of a Novel SHIP1 Phosphatase Activator for Inhibition of PI3K Signaling in Malignant B Cells
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Includes: Supplementary data
Journal Articles

Ibrutinib Therapy Releases Leukemic Surface IgM from Antigen Drive in Chronic Lymphocytic Leukemia Patients

Samantha Drennan, Giorgia Chiodin, Annalisa D'Avola, Ian Tracy, Peter W. Johnson, Livio Trentin, Andrew J. Steele, Graham Packham, Freda K. Stevenson, Francesco Forconi
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (8): 2503–2512.
https://doi.org/10.1158/1078-0432.CCR-18-1286
Published: 15 April 2019
View article titled, Ibrutinib Therapy Releases Leukemic Surface IgM from Antigen Drive in Chronic Lymphocytic Leukemia Patients
Open the PDF for Ibrutinib Therapy Releases Leukemic Surface IgM from Antigen Drive in Chronic Lymphocytic Leukemia Patients in another window
Includes: Supplementary data
Journal Articles

The Dual Syk/JAK Inhibitor Cerdulatinib Antagonizes B-cell Receptor and Microenvironmental Signaling in Chronic Lymphocytic Leukemia

Matthew D. Blunt, Stefan Koehrer, Rachel C. Dobson, Marta Larrayoz, Sarah Wilmore, Alice Hayman, Jack Parnell, Lindsay D. Smith, Andrew Davies, Peter W.M. Johnson, Pamela B. Conley, Anjali Pandey, Jonathan C. Strefford, Freda K. Stevenson, Graham Packham, Francesco Forconi, Greg P. Coffey, Jan A. Burger, Andrew J. Steele
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (9): 2313–2324.
https://doi.org/10.1158/1078-0432.CCR-16-1662
Published: 30 April 2017
View article titled, The Dual Syk/JAK Inhibitor Cerdulatinib Antagonizes B-cell Receptor and Microenvironmental Signaling in Chronic Lymphocytic Leukemia
Open the PDF for The Dual Syk/JAK Inhibitor Cerdulatinib Antagonizes B-cell Receptor and Microenvironmental Signaling in Chronic Lymphocytic Leukemia in another window
Includes: Supplementary data
Journal Articles

Targeting Carcinoembryonic Antigen with DNA Vaccination: On-Target Adverse Events Link with Immunologic and Clinical Outcomes

Katy J. McCann, Ann Mander, Angelica Cazaly, Lindsey Chudley, Jana Stasakova, Stephen M. Thirdborough, Andrew King, Paul Lloyd-Evans, Emily Buxton, Ceri Edwards, Sarah Halford, Andrew Bateman, Ann O'Callaghan, Sally Clive, Alan Anthoney, Duncan I. Jodrell, Toni Weinschenk, Petra Simon, Ugur Sahin, Gareth J. Thomas, Freda K. Stevenson, Christian H. Ottensmeier
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (19): 4827–4836.
https://doi.org/10.1158/1078-0432.CCR-15-2507
Published: 02 October 2016
View article titled, Targeting Carcinoembryonic Antigen with DNA Vaccination: On-Target Adverse Events Link with Immunologic and Clinical Outcomes
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Includes: Supplementary data
Journal Articles

Structural and Functional Features of the B-Cell Receptor in IgG-Positive Chronic Lymphocytic Leukemia

Kathleen N. Potter, C. Ian Mockridge, Louise Neville, Isla Wheatley, Michael Schenk, Jennifer Orchard, Andrew S. Duncombe, Graham Packham, Freda K. Stevenson
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (6): 1672–1679.
https://doi.org/10.1158/1078-0432.CCR-05-2164
Published: 21 March 2006
View article titled, Structural and Functional Features of the B-Cell Receptor in IgG-Positive Chronic Lymphocytic Leukemia
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