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Frank Berthold
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Journal Articles

Revised Risk Estimation and Treatment Stratification of Low- and Intermediate-Risk Neuroblastoma Patients by Integrating Clinical and Molecular Prognostic Markers

André Oberthuer, Dilafruz Juraeva, Barbara Hero, Ruth Volland, Carolina Sterz, Rene Schmidt, Andreas Faldum, Yvonne Kahlert, Anne Engesser, Shahab Asgharzadeh, Robert Seeger, Miki Ohira, Akira Nakagawara, Paola Scaruffi, Gian Paolo Tonini, Isabelle Janoueix-Lerosey, Olivier Delattre, Gudrun Schleiermacher, Jo Vandesompele, Frank Speleman, Rosa Noguera, Marta Piqueras, Jean Bénard, Alexander Valent, Smadar Avigad, Isaac Yaniv, Richard G. Grundy, Monika Ortmann, Chunxuan Shao, Manfred Schwab, Roland Eils, Thorsten Simon, Jessica Theissen, Frank Berthold, Frank Westermann, Benedikt Brors, Matthias Fischer
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (8): 1904–1915.
https://doi.org/10.1158/1078-0432.CCR-14-0817
Published: 14 April 2015
View article titled, Revised Risk Estimation and Treatment Stratification of Low- and Intermediate-Risk Neuroblastoma Patients by Integrating Clinical and Molecular Prognostic Markers
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Includes: Supplementary data
Journal Articles

High ALK Receptor Tyrosine Kinase Expression Supersedes ALK Mutation as a Determining Factor of an Unfavorable Phenotype in Primary Neuroblastoma

Johannes H. Schulte, Hagen S. Bachmann, Bent Brockmeyer, Katleen DePreter, André Oberthür, Sandra Ackermann, Yvonne Kahlert, Kristian Pajtler, Jessica Theissen, Frank Westermann, Jo Vandesompele, Frank Speleman, Frank Berthold, Angelika Eggert, Benedikt Brors, Barbara Hero, Alexander Schramm, Matthias Fischer
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (15): 5082–5092.
https://doi.org/10.1158/1078-0432.CCR-10-2809
Published: 31 July 2011
View article titled, High <em>ALK</em> Receptor Tyrosine Kinase Expression Supersedes <em>ALK</em> Mutation as a Determining Factor of an Unfavorable Phenotype in Primary Neuroblastoma
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Includes: Supplementary data
Journal Articles

Polo-Like Kinase 1 is a Therapeutic Target in High-Risk Neuroblastoma

Sandra Ackermann, Felix Goeser, Johannes H. Schulte, Alexander Schramm, Volker Ehemann, Barbara Hero, Angelika Eggert, Frank Berthold, Matthias Fischer
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (4): 731–741.
https://doi.org/10.1158/1078-0432.CCR-10-1129
Published: 15 February 2011
View article titled, Polo-Like Kinase 1 is a Therapeutic Target in High-Risk Neuroblastoma
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Journal Articles

Heterogeneity of the MYCN Oncogene in Neuroblastoma

Jessica Theissen, Marc Boensch, Ruediger Spitz, David Betts, Sabine Stegmaier, Holger Christiansen, Felix Niggli, Freimut Schilling, Manfred Schwab, Thorsten Simon, Frank Westermann, Frank Berthold, Barbara Hero
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (6): 2085–2090.
https://doi.org/10.1158/1078-0432.CCR-08-1648
Published: 16 March 2009
View article titled, Heterogeneity of the <em>MYCN</em> Oncogene in Neuroblastoma
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Journal Articles

Subclassification and Individual Survival Time Prediction from Gene Expression Data of Neuroblastoma Patients by Using CASPAR

André Oberthuer, Lars Kaderali, Yvonne Kahlert, Barbara Hero, Frank Westermann, Frank Berthold, Benedikt Brors, Roland Eils, Matthias Fischer
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (20): 6590–6601.
https://doi.org/10.1158/1078-0432.CCR-07-4377
Published: 16 October 2008
View article titled, Subclassification and Individual Survival Time Prediction from Gene Expression Data of Neuroblastoma Patients by Using CASPAR
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Includes: Supplementary data
Journal Articles

Differential Expression of Neuronal Genes Defines Subtypes of Disseminated Neuroblastoma with Favorable and Unfavorable Outcome

Matthias Fischer, André Oberthuer, Benedikt Brors, Yvonne Kahlert, Matthias Skowron, Harald Voth, Patrick Warnat, Karen Ernestus, Barbara Hero, Frank Berthold
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (17): 5118–5128.
https://doi.org/10.1158/1078-0432.CCR-06-0985
Published: 01 September 2006
View article titled, Differential Expression of Neuronal Genes Defines Subtypes of Disseminated Neuroblastoma with Favorable and Unfavorable Outcome
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Includes: Supplementary data
Journal Articles

Loss in Chromosome 11q Identifies Tumors with Increased Risk for Metastatic Relapses in Localized and 4S Neuroblastoma

Ruediger Spitz, Barbara Hero, Thorsten Simon, Frank Berthold
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (11): 3368–3373.
https://doi.org/10.1158/1078-0432.CCR-05-2495
Published: 01 June 2006
View article titled, Loss in Chromosome 11q Identifies Tumors with Increased Risk for Metastatic Relapses in Localized and 4S Neuroblastoma
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Journal Articles

Reduced Expression of CAMTA1 Correlates with Adverse Outcome in Neuroblastoma Patients

Kai-Oliver Henrich, Matthias Fischer, Daniel Mertens, Axel Benner, Ruprecht Wiedemeyer, Benedikt Brors, André Oberthuer, Frank Berthold, Jun Stephen Wei, Javed Khan, Manfred Schwab, Frank Westermann
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (1): 131–138.
https://doi.org/10.1158/1078-0432.CCR-05-1431
Published: 05 January 2006
View article titled, Reduced Expression of <em>CAMTA1</em> Correlates with Adverse Outcome in Neuroblastoma Patients
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Journal Articles

The Tumor-Associated Antigen PRAME Is Universally Expressed in High-Stage Neuroblastoma and Associated with Poor Outcome

André Oberthuer, Barbara Hero, Rüdiger Spitz, Frank Berthold, Matthias Fischer
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (13): 4307–4313.
https://doi.org/10.1158/1078-0432.CCR-03-0813
Published: 06 July 2004
View article titled, The Tumor-Associated Antigen <em>PRAME</em> Is Universally Expressed in High-Stage Neuroblastoma and Associated with Poor Outcome
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Journal Articles

Gain of Distal Chromosome Arm 17q Is Not Associated with Poor Prognosis in Neuroblastoma

Ruediger Spitz, Barbara Hero, Karen Ernestus, Frank Berthold
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (13): 4835–4840.
Published: 27 October 2003
View article titled, Gain of Distal Chromosome Arm 17q Is Not Associated with Poor Prognosis in Neuroblastoma
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Journal Articles

Deletions in Chromosome Arms 3p and 11q Are New Prognostic Markers in Localized and 4s Neuroblastoma

Ruediger Spitz, Barbara Hero, Karen Ernestus, Frank Berthold
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (1): 52–58.
Published: 01 January 2003
View article titled, Deletions in Chromosome Arms 3p and 11q Are New Prognostic Markers in Localized and 4s Neuroblastoma
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