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Frank B. Furnari
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Journal Articles

The mTOR Kinase Inhibitors, CC214-1 and CC214-2, Preferentially Block the Growth of EGFRvIII-Activated Glioblastomas

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Beatrice Gini, Ciro Zanca, Deliang Guo, Tomoo Matsutani, Kenta Masui, Shiro Ikegami, Huijun Yang, David Nathanson, Genaro R. Villa, David Shackelford, Shaojun Zhu, Kazuhiro Tanaka, Ivan Babic, David Akhavan, Kelly Lin, Alvaro Assuncao, Yuchao Gu, Bruno Bonetti, Deborah S. Mortensen, Shuichan Xu, Heather K. Raymon, Webster K. Cavenee, Frank B. Furnari, C. David James, Guido Kroemer, James R. Heath, Kristen Hege, Rajesh Chopra, Timothy F. Cloughesy, Paul S. Mischel
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (20): 5722–5732.
https://doi.org/10.1158/1078-0432.CCR-13-0527
Published: 14 October 2013
View articletitled, The mTOR Kinase Inhibitors, CC214-1 and CC214-2, Preferentially Block the Growth of EGFRvIII-Activated Glioblastomas
Open the PDF for The mTOR Kinase Inhibitors, CC214-1 and CC214-2, Preferentially Block the Growth of EGFRvIII-Activated Glioblastomas in another window
Includes: Supplementary data
Journal Articles

The Efficacy of Epidermal Growth Factor Receptor–Specific Antibodies against Glioma Xenografts Is Influenced by Receptor Levels, Activation Status, and Heterodimerization

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Terrance G. Johns, Rushika M. Perera, Sonja C. Vernes, Angela A. Vitali, Diana X. Cao, Webster K. Cavenee, Andrew M. Scott, Frank B. Furnari
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (6): 1911–1925.
https://doi.org/10.1158/1078-0432.CCR-06-1453
Published: 15 March 2007
View articletitled, The Efficacy of Epidermal Growth Factor Receptor–Specific Antibodies against Glioma Xenografts Is Influenced by Receptor Levels, Activation Status, and Heterodimerization
Open the PDF for The Efficacy of Epidermal Growth Factor Receptor–Specific Antibodies against Glioma Xenografts Is Influenced by Receptor Levels, Activation Status, and Heterodimerization in another window
Journal Articles

Mutant Epidermal Growth Factor Receptor (EGFRvIII) Contributes to Head and Neck Cancer Growth and Resistance to EGFR Targeting

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John C. Sok, Francesca M. Coppelli, Sufi M. Thomas, Miriam N. Lango, Sichuan Xi, Jennifer L. Hunt, Maria L. Freilino, Michael W. Graner, Carol J. Wikstrand, Darell D. Bigner, William E. Gooding, Frank B. Furnari, Jennifer R. Grandis
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (17): 5064–5073.
https://doi.org/10.1158/1078-0432.CCR-06-0913
Published: 01 September 2006
View articletitled, Mutant Epidermal Growth Factor Receptor (EGFRvIII) Contributes to Head and Neck Cancer Growth and Resistance to EGFR Targeting
Open the PDF for Mutant Epidermal Growth Factor Receptor (EGFRvIII) Contributes to Head and Neck Cancer Growth and Resistance to EGFR Targeting in another window
Journal Articles

Treatment of Human Tumor Xenografts with Monoclonal Antibody 806 in Combination with a Prototypical Epidermal Growth Factor Receptor–Specific Antibody Generates Enhanced Antitumor Activity

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Rushika M. Perera, Yoshitaka Narita, Frank B. Furnari, Hui K. Gan, Carmel Murone, Marika Ahlkvist, Rodney B. Luwor, Antony W. Burgess, Elisabeth Stockert, Achim A. Jungbluth, Lloyd J. Old, Webster K. Cavenee, Andrew M. Scott, Terrance G. Johns
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (17): 6390–6399.
https://doi.org/10.1158/1078-0432.CCR-04-2653
Published: 06 September 2005
View articletitled, Treatment of Human Tumor Xenografts with Monoclonal Antibody 806 in Combination with a Prototypical Epidermal Growth Factor Receptor–Specific Antibody Generates Enhanced Antitumor Activity
Open the PDF for Treatment of Human Tumor Xenografts with Monoclonal Antibody 806 in Combination with a Prototypical Epidermal Growth Factor Receptor–Specific Antibody Generates Enhanced Antitumor Activity in another window