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Journal Articles

Ultrasmall Nanoparticle Delivery of Doxorubicin Improves Therapeutic Index for High-Grade Glioma

Virginia Aragon-Sanabria, Anusha Aditya, Li Zhang, Feng Chen, Barney Yoo, Tianye Cao, Brian Madajewski, Rachel Lee, Melik Z. Turker, Kai Ma, Sebastien Monette, Peiming Chen, Jing Wu, Shutian Ruan, Michael Overholtzer, Pat Zanzonico, Charles M. Rudin, Cameron Brennan, Ulrich Wiesner, Michelle S. Bradbury
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (13): 2938–2952.
https://doi.org/10.1158/1078-0432.CCR-21-4053
Published: 01 July 2022
View article titled, Ultrasmall Nanoparticle Delivery of Doxorubicin Improves Therapeutic Index for High-Grade Glioma
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Includes: Supplementary data
Journal Articles

Molecular Engineering of Ultrasmall Silica Nanoparticle–Drug Conjugates as Lung Cancer Therapeutics

Brian Madajewski, Feng Chen, Barney Yoo, Melik Z. Turker, Kai Ma, Li Zhang, Pei-Ming Chen, Rupa Juthani, Virginia Aragon-Sanabria, Mithat Gonen, Charles M. Rudin, Ulrich Wiesner, Michelle S. Bradbury, Cameron Brennan
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (20): 5424–5437.
https://doi.org/10.1158/1078-0432.CCR-20-0851
Published: 15 October 2020
View article titled, Molecular Engineering of Ultrasmall Silica Nanoparticle–Drug Conjugates as Lung Cancer Therapeutics
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Includes: Supplementary data
Journal Articles

Ultrasmall Core-Shell Silica Nanoparticles for Precision Drug Delivery in a High-Grade Malignant Brain Tumor Model

Rupa Juthani, Brian Madajewski, Barney Yoo, Li Zhang, Pei-Ming Chen, Feng Chen, Melik Z. Turker, Kai Ma, Michael Overholtzer, Valerie A. Longo, Sean Carlin, Virginia Aragon-Sanabria, Jason Huse, Mithat Gonen, Pat Zanzonico, Charles M. Rudin, Ulrich Wiesner, Michelle S. Bradbury, Cameron W. Brennan
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (1): 147–158.
https://doi.org/10.1158/1078-0432.CCR-19-1834
Published: 03 January 2020
View article titled, Ultrasmall Core-Shell Silica Nanoparticles for Precision Drug Delivery in a High-Grade Malignant Brain Tumor Model
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Includes: Multimedia, Supplementary data
Journal Articles

Dendritic Cell/Cytokine-Induced Killer Cell Immunotherapy Combined with S-1 in Patients with Advanced Pancreatic Cancer: A Prospective Study

Ni Jiang, Guoliang Qiao, Xiaoli Wang, Michael A. Morse, William R. Gwin, Lei Zhou, Yuguang Song, Yanjie Zhao, Feng Chen, Xinna Zhou, Lefu Huang, Amy Hobeika, Xin Yi, Xuefeng Xia, Yanfang Guan, Jin Song, Jun Ren, H. Kim Lyerly
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (17): 5066–5073.
https://doi.org/10.1158/1078-0432.CCR-17-0492
Published: 31 August 2017
View article titled, Dendritic Cell/Cytokine-Induced Killer Cell Immunotherapy Combined with S-1 in Patients with Advanced Pancreatic Cancer: A Prospective Study
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Includes: Supplementary data
Journal Articles

STAT3 Mediates Regorafenib-Induced Apoptosis in Hepatocellular Carcinoma

Wei-Tien Tai, Pei-Yi Chu, Chung-Wai Shiau, Yao-Li Chen, Yong-Shi Li, Man-Hsin Hung, Li-Ju Chen, Pei-Lung Chen, Jung-Chen Su, Ping-Yi Lin, Hui-Chuan Yu, Kuen-Feng Chen
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (22): 5768–5776.
https://doi.org/10.1158/1078-0432.CCR-14-0725
Published: 13 November 2014
View article titled, STAT3 Mediates Regorafenib-Induced Apoptosis in Hepatocellular Carcinoma
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Journal Articles

Enhanced Metastasis Suppression by Targeting TRAIL Receptor 2 in a Murine Model of Triple-Negative Breast Cancer

Dmitry Malin, Feng Chen, Carol Schiller, Jennifer Koblinski, Vincent L. Cryns
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (15): 5005–5015.
https://doi.org/10.1158/1078-0432.CCR-11-0099
Published: 31 July 2011
View article titled, Enhanced Metastasis Suppression by Targeting TRAIL Receptor 2 in a Murine Model of Triple-Negative Breast Cancer
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Journal Articles

Sorafenib Overcomes TRAIL Resistance of Hepatocellular Carcinoma Cells through the Inhibition of STAT3

Kuen-Feng Chen, Wei-Tien Tai, Tsung-Hao Liu, Hsiang-Po Huang, Yu-Chin Lin, Chung-Wai Shiau, Pui-Kai Li, Pei-Jer Chen, Ann-Lii Cheng
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (21): 5189–5199.
https://doi.org/10.1158/1078-0432.CCR-09-3389
Published: 31 October 2010
View article titled, Sorafenib Overcomes TRAIL Resistance of Hepatocellular Carcinoma Cells through the Inhibition of STAT3
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Journal Articles

A Novel Nanoparticulate Formulation of Arsenic Trioxide with Enhanced Therapeutic Efficacy in a Murine Model of Breast Cancer

Richard W. Ahn, Feng Chen, Haimei Chen, Stephan T. Stern, Jeffrey D. Clogston, Anil K. Patri, Meera R. Raja, Elden P. Swindell, Vamsi Parimi, Vincent L. Cryns, Thomas V. O'Halloran
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (14): 3607–3617.
https://doi.org/10.1158/1078-0432.CCR-10-0068
Published: 14 July 2010
View article titled, A Novel Nanoparticulate Formulation of Arsenic Trioxide with Enhanced Therapeutic Efficacy in a Murine Model of Breast Cancer
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Includes: Supplementary data
Journal Articles

Aspirin Sensitizes Cancer Cells to TRAIL–Induced Apoptosis by Reducing Survivin Levels

Meiling Lu, Anne Strohecker, Feng Chen, Toni Kwan, Joshua Bosman, V. Craig Jordan, Vincent L. Cryns
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (10): 3168–3176.
https://doi.org/10.1158/1078-0432.CCR-07-4362
Published: 15 May 2008
View article titled, Aspirin Sensitizes Cancer Cells to TRAIL–Induced Apoptosis by Reducing Survivin Levels
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Journal Articles

Rapid Identification of UCA1 as a Very Sensitive and Specific Unique Marker for Human Bladder Carcinoma

Xiao-Song Wang, Zheng Zhang, Hong-Cheng Wang, Jian-Liang Cai, Qing-Wen Xu, Meng-Qiang Li, Yi-Cheng Chen, Xiao-Ping Qian, Tian-Jing Lu, Li-Zhang Yu, Yu Zhang, Dian-Qi Xin, Yan-Qun Na, Wei-Feng Chen
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (16): 4851–4858.
https://doi.org/10.1158/1078-0432.CCR-06-0134
Published: 16 August 2006
View article titled, Rapid Identification of UCA1 as a Very Sensitive and Specific Unique Marker for Human Bladder Carcinoma
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Includes: Supplementary data
Journal Articles

The Spontaneous CD8+ T-Cell Response to HLA-A2-Restricted NY-ESO-1b Peptide in Hepatocellular Carcinoma Patients

Xiao-Ying Shang, Hong-Song Chen, Hua-Gang Zhang, Xue-Wen Pang, Huan Qiao, Ji-Run Peng, Li-Ling Qin, Ran Fei, Ming-Hui Mei, Xi-Sheng Leng, Sacha Gnjatic, Gerd Ritter, Andrew J. G. Simpson, Lloyd J. Old, Wei-Feng Chen
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (20): 6946–6955.
https://doi.org/10.1158/1078-0432.CCR-04-0502
Published: 22 October 2004
View article titled, The Spontaneous CD8<sup>+</sup> T-Cell Response to HLA-A2-Restricted NY-ESO-1b Peptide in Hepatocellular Carcinoma Patients
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Journal Articles

Defective Expression of Transforming Growth Factor β Receptor Type II Is Associated with CpG Methylated Promoter in Primary Non-Small Cell Lung Cancer

Hong-Tao Zhang, Xiao-Feng Chen, Ming-Hua Wang, Jiu-Cun Wang, Qing-Yuan Qi, Rong-Mei Zhang, Wei-Qing Xu, Qing-Yan Fei, Fei Wang, Qi-Qun Cheng, Feng Chen, Cheng-Song Zhu, Shi-Heng Tao, Zewei Luo
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (7): 2359–2367.
https://doi.org/10.1158/1078-0432.CCR-0959-3
Published: 08 April 2004
View article titled, Defective Expression of Transforming Growth Factor β Receptor Type II Is Associated with CpG Methylated Promoter in Primary Non-Small Cell Lung Cancer
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