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Ewa Sicinska
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Journal Articles

Preclinical Modeling of Leiomyosarcoma Identifies Susceptibility to Transcriptional CDK Inhibitors through Antagonism of E2F-Driven Oncogenic Gene Expression

Matthew L. Hemming, Patrick Bhola, Michael A. Loycano, Justin A. Anderson, Madeleine L. Taddei, Leona A. Doyle, Elizaveta Lavrova, Jessica L. Andersen, Kelly S. Klega, Morgan R. Benson, Brian D. Crompton, Chandrajit P. Raut, Suzanne George, Anthony Letai, George D. Demetri, Ewa Sicinska
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (11): 2397–2408.
https://doi.org/10.1158/1078-0432.CCR-21-3523
Published: 01 June 2022
View article titled, Preclinical Modeling of Leiomyosarcoma Identifies Susceptibility to Transcriptional CDK Inhibitors through Antagonism of E2F-Driven Oncogenic Gene Expression
Open the PDF for Preclinical Modeling of Leiomyosarcoma Identifies Susceptibility to Transcriptional CDK Inhibitors through Antagonism of E2F-Driven Oncogenic Gene Expression in another window
Includes: Supplementary data
Journal Articles

Molecular Characterization and Therapeutic Targeting of Colorectal Cancers Harboring Receptor Tyrosine Kinase Fusions

Harshabad Singh, Yvonne Y. Li, Liam F. Spurr, Atul B. Shinagare, Ritika Abhyankar, Emma Reilly, Lauren K. Brais, Anwesha Nag, Matthew D. Ducar, Aaron R. Thorner, Geoffrey I. Shapiro, Rachel B. Keller, Cheta Siletti, Jeffrey W. Clark, Anna F. Farago, Jessica J. Lin, George D. Demetri, Rahul Gujrathi, Matthew H. Kulke, Laura E. MacConaill, Azra H. Ligon, Ewa Sicinska, Matthew L. Meyerson, Jeffrey A. Meyerhardt, Andrew D. Cherniack, Brian M. Wolpin, Kimmie Ng, Marios Giannakis, Jason L. Hornick, James M. Cleary
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (6): 1695–1705.
https://doi.org/10.1158/1078-0432.CCR-20-4073
Published: 15 March 2021
View article titled, Molecular Characterization and Therapeutic Targeting of Colorectal Cancers Harboring Receptor Tyrosine Kinase Fusions
Open the PDF for Molecular Characterization and Therapeutic Targeting of Colorectal Cancers Harboring Receptor Tyrosine Kinase Fusions in another window
Includes: Supplementary data
Journal Articles

Abstract B13: Human pancreatic cancer organoids for functional dependency profiling

Srivatsan Raghavan, Shubhroz Gill, Andrew J. Aguirre, Yuen-Yi M. Tseng, Anson Peng, Paula Keskula, Xiaoyun Wu, Coyin Oh, Jamie Cheah, Gregory Kryukov, Ewa Sicinska, Brian M. Wolpin, Matthew H. Kulke, Charles S. Fuchs, Paul Clemons, Todd R. Golub, Stuart Schreiber, Jesse S. Boehm, William C. Hahn
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16_Supplement): B13.
https://doi.org/10.1158/1557-3265.PDX16-B13
Published: 15 August 2016
View article titled, Abstract B13: Human pancreatic cancer organoids for functional dependency profiling
Journal Articles

Functional Profiling of Receptor Tyrosine Kinases and Downstream Signaling in Human Chondrosarcomas Identifies Pathways for Rational Targeted Therapy

Yi-Xiang Zhang, Jolieke G. van Oosterwijk, Ewa Sicinska, Samuel Moss, Stephen P. Remillard, Tom van Wezel, Claudia Bühnemann, Andrew B. Hassan, George D. Demetri, Judith V.M.G. Bovée, Andrew J. Wagner
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2013) 19 (14): 3796–3807.
https://doi.org/10.1158/1078-0432.CCR-12-3647
Published: 15 July 2013
View article titled, Functional Profiling of Receptor Tyrosine Kinases and Downstream Signaling in Human Chondrosarcomas Identifies Pathways for Rational Targeted Therapy
Open the PDF for Functional Profiling of Receptor Tyrosine Kinases and Downstream Signaling in Human Chondrosarcomas Identifies Pathways for Rational Targeted Therapy in another window
Includes: Supplementary data