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Eudocia Q. Lee
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Journal Articles

Phase I Study of Adavosertib with Radiotherapy and Temozolomide in Newly Diagnosed Glioblastoma and Intratumoral Drug Levels in Recurrent Glioblastoma

Eudocia Q. Lee, Brian M. Alexander, Carlos G. Romo, Jeffrey G. Supko, Nathalie Y.R. Agar, Zahra Talebi, Manmeet S. Ahluwalia, Arati S. Desai, Jorg Dietrich, Thomas J. Kaley, David M. Peereboom, Jennifer Gantchev, Gerard Baquer, Sandro Santagata, Naoko Takebe, Serena Desideri, Joy D. Fisher, Megan Sims, Xiaobu Ye, Keith L. Ligon, Louis B. Nabors, Stuart A. Grossman, Patrick Y. Wen
Journal: Clinical Cancer Research
Clin Cancer Res OF1–OF10.
https://doi.org/10.1158/1078-0432.CCR-24-2311
Published: 12 February 2025
View article titled, Phase I Study of Adavosertib with Radiotherapy and Temozolomide in Newly Diagnosed Glioblastoma and Intratumoral Drug Levels in Recurrent Glioblastoma
Open the PDF for Phase I Study of Adavosertib with Radiotherapy and Temozolomide in Newly Diagnosed Glioblastoma and Intratumoral Drug Levels in Recurrent Glioblastoma in another window
Includes: Supplementary data
Journal Articles

Clinical and Genomic Predictors of Adverse Events in Newly Diagnosed Glioblastoma

Mary Jane Lim-Fat, J. Bryan Iorgulescu, Rifaquat Rahman, Varun Bhave, Alona Muzikansky, Eleanor Woodward, Sydney Whorral, Marie Allen, Mehdi Touat, Xiaomei Li, Gongwen Xy, Jay Patel, Elizabeth R. Gerstner, Jayashree Kalpathy-Cramer, Gilbert Youssef, Ugonma Chukwueke, J. Ricardo McFaline-Figueroa, Lakshmi Nayak, Eudocia Q. Lee, David A. Reardon, Rameen Beroukhim, Raymond Y. Huang, Wenya Linda Bi, Keith L. Ligon, Patrick Y. Wen
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (7): 1327–1337.
https://doi.org/10.1158/1078-0432.CCR-23-3018
Published: 01 April 2024
View article titled, Clinical and Genomic Predictors of Adverse Events in Newly Diagnosed Glioblastoma
Open the PDF for Clinical and Genomic Predictors of Adverse Events in Newly Diagnosed Glioblastoma in another window
Includes: Supplementary data
Journal Articles

Bavituximab Decreases Immunosuppressive Myeloid-Derived Suppressor Cells in Newly Diagnosed Glioblastoma Patients

K. Ina Ly, Leland G. Richardson, Mofei Liu, Alona Muzikansky, Jonathan Cardona, Kevin Lou, Andrew L. Beers, Ken Chang, James M. Brown, Xiaoyue Ma, David A. Reardon, Isabel C. Arrillaga-Romany, Deborah A. Forst, Justin T. Jordan, Eudocia Q. Lee, Jorg Dietrich, Lakshmi Nayak, Patrick Y. Wen, Ugonma Chukwueke, Anita Giobbie-Hurder, Bryan D. Choi, Tracy T. Batchelor, Jayashree Kalpathy-Cramer, William T. Curry, Elizabeth R. Gerstner
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (16): 3017–3025.
https://doi.org/10.1158/1078-0432.CCR-23-0203
Published: 15 August 2023
View article titled, Bavituximab Decreases Immunosuppressive Myeloid-Derived Suppressor Cells in Newly Diagnosed Glioblastoma Patients
Open the PDF for Bavituximab Decreases Immunosuppressive Myeloid-Derived Suppressor Cells in Newly Diagnosed Glioblastoma Patients in another window
Includes: Supplementary data
Journal Articles

Glioblastoma Clinical Trials: Current Landscape and Opportunities for Improvement

Stephen J. Bagley, Shawn Kothari, Rifaquat Rahman, Eudocia Q. Lee, Gavin P. Dunn, Evanthia Galanis, Susan M. Chang, Louis Burt Nabors, Manmeet S. Ahluwalia, Roger Stupp, Minesh P. Mehta, David A. Reardon, Stuart A. Grossman, Erik P. Sulman, John H. Sampson, Simon Khagi, Michael Weller, Timothy F. Cloughesy, Patrick Y. Wen, Mustafa Khasraw
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (4): 594–602.
https://doi.org/10.1158/1078-0432.CCR-21-2750
Published: 15 February 2022
View article titled, Glioblastoma Clinical Trials: Current Landscape and Opportunities for Improvement
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Journal Articles

First-in-Human Phase I Study to Evaluate the Brain-Penetrant PI3K/mTOR Inhibitor GDC-0084 in Patients with Progressive or Recurrent High-Grade Glioma

Patrick Y. Wen, Timothy F. Cloughesy, Alan G. Olivero, Kari M. Morrissey, Timothy R. Wilson, Xuyang Lu, Lars U. Mueller, Alexandre F. Coimbra, Benjamin M. Ellingson, Elizabeth Gerstner, Eudocia Q. Lee, Jordi Rodon
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (8): 1820–1828.
https://doi.org/10.1158/1078-0432.CCR-19-2808
Published: 15 April 2020
View article titled, First-in-Human Phase I Study to Evaluate the Brain-Penetrant PI3K/mTOR Inhibitor GDC-0084 in Patients with Progressive or Recurrent High-Grade Glioma
Open the PDF for First-in-Human Phase I Study to Evaluate the Brain-Penetrant PI3K/mTOR Inhibitor GDC-0084 in Patients with Progressive or Recurrent High-Grade Glioma in another window
Journal Articles

Phase I and Biomarker Study of Plerixafor and Bevacizumab in Recurrent High-Grade Glioma

Eudocia Q. Lee, Dan G. Duda, Alona Muzikansky, Elizabeth R. Gerstner, John G. Kuhn, David A. Reardon, Lakshmi Nayak, Andrew D. Norden, Lisa Doherty, Debra LaFrankie, Jennifer Stefanik, Trupti Vardam, Katrina H. Smith, Christine McCluskey, Sarah Gaffey, Tracy T. Batchelor, Rakesh K. Jain, Patrick Y. Wen
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (19): 4643–4649.
https://doi.org/10.1158/1078-0432.CCR-18-1025
Published: 01 October 2018
View article titled, Phase I and Biomarker Study of Plerixafor and Bevacizumab in Recurrent High-Grade Glioma
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Journal Articles

The Impact of T2/FLAIR Evaluation per RANO Criteria on Response Assessment of Recurrent Glioblastoma Patients Treated with Bevacizumab

Raymond Y. Huang, Rifaquat Rahman, Karla V. Ballman, Sara J. Felten, S. Keith Anderson, Benjamin M. Ellingson, Lakshmi Nayak, Eudocia Q. Lee, Lauren E. Abrey, Evanthia Galanis, David A. Reardon, Whitney B. Pope, Timothy F. Cloughesy, Patrick Y. Wen
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (3): 575–581.
https://doi.org/10.1158/1078-0432.CCR-14-3040
Published: 31 January 2016
View article titled, The Impact of T2/FLAIR Evaluation per RANO Criteria on Response Assessment of Recurrent Glioblastoma Patients Treated with Bevacizumab
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Journal Articles

A Multicenter, Phase II, Randomized, Noncomparative Clinical Trial of Radiation and Temozolomide with or without Vandetanib in Newly Diagnosed Glioblastoma Patients

Eudocia Q. Lee, Thomas J. Kaley, Dan G. Duda, David Schiff, Andrew B. Lassman, Eric T. Wong, Tom Mikkelsen, Benjamin W. Purow, Alona Muzikansky, Marek Ancukiewicz, Jason T. Huse, Shakti Ramkissoon, Jan Drappatz, Andrew D. Norden, Rameen Beroukhim, Stephanie E. Weiss, Brian M. Alexander, Christine S. McCluskey, Mary Gerard, Katrina H. Smith, Rakesh K. Jain, Tracy T. Batchelor, Keith L. Ligon, Patrick Y. Wen
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (16): 3610–3618.
https://doi.org/10.1158/1078-0432.CCR-14-3220
Published: 13 August 2015
View article titled, A Multicenter, Phase II, Randomized, Noncomparative Clinical Trial of Radiation and Temozolomide with or without Vandetanib in Newly Diagnosed Glioblastoma Patients
Open the PDF for A Multicenter, Phase II, Randomized, Noncomparative Clinical Trial of Radiation and Temozolomide with or without Vandetanib in Newly Diagnosed Glioblastoma Patients in another window
Includes: Supplementary data
Journal Articles

Phase I Study of Vorinostat in Combination with Temozolomide in Patients with High-Grade Gliomas: North American Brain Tumor Consortium Study 04-03

Eudocia Q. Lee, Vinay K. Puduvalli, Joel M. Reid, John G. Kuhn, Kathleen R. Lamborn, Timothy F. Cloughesy, Susan M. Chang, Jan Drappatz, W. K. Alfred Yung, Mark R. Gilbert, H. Ian Robins, Frank S. Lieberman, Andrew B. Lassman, Renee M. McGovern, Jihong Xu, Serena Desideri, Xiabu Ye, Matthew M. Ames, Igor Espinoza-Delgado, Michael D. Prados, Patrick Y. Wen
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (21): 6032–6039.
https://doi.org/10.1158/1078-0432.CCR-12-1841
Published: 06 November 2012
View article titled, Phase I Study of Vorinostat in Combination with Temozolomide in Patients with High-Grade Gliomas: North American Brain Tumor Consortium Study 04-03
Open the PDF for Phase I Study of Vorinostat in Combination with Temozolomide in Patients with High-Grade Gliomas: North American Brain Tumor Consortium Study 04-03 in another window
Includes: Supplementary data