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Erin R. Gardner
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Journal Articles

Sorafenib Is an Inhibitor of UGT1A1 but Is Metabolized by UGT1A9: Implications of Genetic Variants on Pharmacokinetics and Hyperbilirubinemia

Free
Cody J. Peer, Tristan M. Sissung, AeRang Kim, Lokesh Jain, Sukyung Woo, Erin R. Gardner, C. Tyler Kirkland, Sarah M. Troutman, Bevin C. English, Emily D. Richardson, Joel Federspiel, David Venzon, William Dahut, Elise Kohn, Shivaani Kummar, Robert Yarchoan, Giuseppe Giaccone, Brigitte Widemann, William D. Figg
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (7): 2099–2107.
https://doi.org/10.1158/1078-0432.CCR-11-2484
Published: 01 April 2012
View articletitled, Sorafenib Is an Inhibitor of UGT1A1 but Is Metabolized by UGT1A9: Implications of Genetic Variants on Pharmacokinetics and Hyperbilirubinemia
Open the PDF for Sorafenib Is an Inhibitor of UGT1A1 but Is Metabolized by UGT1A9: Implications of Genetic Variants on Pharmacokinetics and Hyperbilirubinemia in another window
Includes: Supplementary data
Journal Articles

Impact of ABCB1 Allelic Variants on QTc Interval Prolongation

Free
Tristan M. Sissung, Erin R. Gardner, Richard L. Piekarz, Reuben Howden, Xiaohong Chen, Sukyung Woo, Ryan Franke, James A. Clark, Laura Miller-DeGraff, Seth M. Steinberg, David Venzon, David Liewehr, Steven R. Kleeberger, Susan E. Bates, Douglas K. Price, Douglas R. Rosing, Christopher Cabell, Alex Sparreboom, William D. Figg
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (4): 937–946.
https://doi.org/10.1158/1078-0432.CCR-10-0925
Published: 15 February 2011
View articletitled, Impact of ABCB1 Allelic Variants on QTc Interval Prolongation
Open the PDF for Impact of ABCB1 Allelic Variants on QTc Interval Prolongation in another window
Includes: Supplementary data
Journal Articles

A Pharmacodynamic Study of Docetaxel in Combination with the P-glycoprotein Antagonist Tariquidar (XR9576) in Patients with Lung, Ovarian, and Cervical Cancer

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Ronan J. Kelly, Deborah Draper, Clara C. Chen, Robert W. Robey, William D. Figg, Richard L. Piekarz, Xiaohong Chen, Erin R. Gardner, Frank M. Balis, Aradhana M. Venkatesan, Seth M. Steinberg, Tito Fojo, Susan E. Bates
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (3): 569–580.
https://doi.org/10.1158/1078-0432.CCR-10-1725
Published: 01 February 2011
View articletitled, A Pharmacodynamic Study of Docetaxel in Combination with the P-glycoprotein Antagonist Tariquidar (XR9576) in Patients with Lung, Ovarian, and Cervical Cancer
Open the PDF for A Pharmacodynamic Study of Docetaxel in Combination with the P-glycoprotein Antagonist Tariquidar (XR9576) in Patients with Lung, Ovarian, and Cervical Cancer in another window
Includes: Supplementary data
Journal Articles

Population Pharmacokinetics of Romidepsin in Patients with Cutaneous T-Cell Lymphoma and Relapsed Peripheral T-Cell Lymphoma

Free
Sukyung Woo, Erin R. Gardner, Xiaohong Chen, Sandra B. Ockers, Caitlin E. Baum, Tristan M. Sissung, Douglas K. Price, Robin Frye, Richard L. Piekarz, Susan E. Bates, William D. Figg
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (4): 1496–1503.
https://doi.org/10.1158/1078-0432.CCR-08-1215
Published: 19 February 2009
View articletitled, Population Pharmacokinetics of Romidepsin in Patients with Cutaneous T-Cell Lymphoma and Relapsed Peripheral T-Cell Lymphoma
Open the PDF for Population Pharmacokinetics of Romidepsin in Patients with Cutaneous T-Cell Lymphoma and Relapsed Peripheral T-Cell Lymphoma in another window
Journal Articles

Randomized Crossover Pharmacokinetic Study of Solvent-Based Paclitaxel and nab-Paclitaxel

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Erin R. Gardner, William L. Dahut, Charity D. Scripture, Jacquin Jones, Jeanny B. Aragon-Ching, Neil Desai, Michael J. Hawkins, Alex Sparreboom, William D. Figg
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (13): 4200–4205.
https://doi.org/10.1158/1078-0432.CCR-07-4592
Published: 01 July 2008
View articletitled, Randomized Crossover Pharmacokinetic Study of Solvent-Based Paclitaxel and nab-Paclitaxel
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Journal Articles

Phase I Trial of MS-275, a Histone Deacetylase Inhibitor, Administered Weekly in Refractory Solid Tumors and Lymphoid Malignancies

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Shivaani Kummar, Martin Gutierrez, Erin R. Gardner, Erin Donovan, Kyunghwa Hwang, Eun Joo Chung, Min-Jung Lee, Kim Maynard, Mikhail Kalnitskiy, Alice Chen, Giovanni Melillo, Qin C. Ryan, Barbara Conley, William D. Figg, Jane B. Trepel, James Zwiebel, James H. Doroshow, Anthony J. Murgo
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (18): 5411–5417.
https://doi.org/10.1158/1078-0432.CCR-07-0791
Published: 17 September 2007
View articletitled, Phase I Trial of MS-275, a Histone Deacetylase Inhibitor, Administered Weekly in Refractory Solid Tumors and Lymphoid Malignancies
Open the PDF for Phase I Trial of MS-275, a Histone Deacetylase Inhibitor, Administered Weekly in Refractory Solid Tumors and Lymphoid Malignancies in another window
Journal Articles

Nelfinavir, A Lead HIV Protease Inhibitor, Is a Broad-Spectrum, Anticancer Agent that Induces Endoplasmic Reticulum Stress, Autophagy, and Apoptosis In vitro and In vivo

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Joell J. Gills, Jaclyn LoPiccolo, Junji Tsurutani, Robert H. Shoemaker, Carolyn J.M. Best, Mones S. Abu-Asab, Jennifer Borojerdi, Noel A. Warfel, Erin R. Gardner, Matthew Danish, M. Christine Hollander, Shigeru Kawabata, Maria Tsokos, William D. Figg, Patricia S. Steeg, Phillip A. Dennis
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (17): 5183–5194.
https://doi.org/10.1158/1078-0432.CCR-07-0161
Published: 04 September 2007
View articletitled, Nelfinavir, A Lead HIV Protease Inhibitor, Is a Broad-Spectrum, Anticancer Agent that Induces Endoplasmic Reticulum Stress, Autophagy, and Apoptosis In vitro and In vivo
Open the PDF for Nelfinavir, A Lead HIV Protease Inhibitor, Is a Broad-Spectrum, Anticancer Agent that Induces Endoplasmic Reticulum Stress, Autophagy, and Apoptosis In vitro and In vivo in another window
Includes: Supplementary data