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Enzo Medico
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Journal Articles

Precision Oncology and Systemic Targeted Therapy in Pseudomyxoma Peritonei

Jordi Martínez-Quintanilla, Débora Cabot, Doménico Sabia, Oriol Arqués, for the PMPnet Group, Jordi Vergés, Irene Chicote, Lana Bijelic, for the PMPnet Group, Laia Cabellos, Anna M. Alcántara, Isabel Ramos, Pedro Barrios, Oriol Crusellas, Lina M. Palacio, for the PMPnet Group, Juan A. Cámara, Jorge Barriuso, for the PMPnet Group, Juan J. Jiménez, Pau Muñoz-Torres, Lara Nonell, Raquel Flores, Enzo Médico, Marcello Guaglio, for the PMPnet Group, Javier Ros, Elena Élez, Josep Tabernero, Omer Aziz, Marcello Deraco, Héctor G. Palmer, for the PMPnet Group, PMPnet Group, Chiorino Giovanna, Mazzarotto Francesco, Gariboldi Manuela, Varinelli Luca, Cavalleri Tommaso, Chakrabarty Bipasha, Nagaraju Raghavendar, Caswell Patrick, McAllister Milly
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (18): 4082–4099.
https://doi.org/10.1158/1078-0432.CCR-23-4072
Published: 13 September 2024
View article titled, Precision Oncology and Systemic Targeted Therapy in Pseudomyxoma Peritonei
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Includes: Supplementary data
Journal Articles

Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer

Adam Lafferty, Alice C. O'Farrell, Giorgia Migliardi, Niraj Khemka, Andreas U. Lindner, Francesco Sassi, Eugenia R. Zanella, Manuela Salvucci, Evy Vanderheyden, Elodie Modave, Bram Boeckx, Luise Halang, Johannes Betge, Matthias P.A. Ebert, Patrick Dicker, Guillem Argilés, Josep Tabernero, Rodrigo Dienstmann, Enzo Medico, Diether Lambrechts, Andrea Bertotti, Claudio Isella, Livio Trusolino, Jochen H.M. Prehn, Annette T. Byrne
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (21): 5979–5992.
https://doi.org/10.1158/1078-0432.CCR-21-0818
Published: 01 November 2021
View article titled, Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer
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Includes: Supplementary data
Journal Articles

CSPG4-Specific CAR.CIK Lymphocytes as a Novel Therapy for the Treatment of Multiple Soft-Tissue Sarcoma Histotypes

Valeria Leuci, Chiara Donini, Giovanni Grignani, Ramona Rotolo, Giulia Mesiano, Erika Fiorino, Loretta Gammaitoni, Lorenzo D'Ambrosio, Alessandra Merlini, Elisa Landoni, Enzo Medico, Sonia Capellero, Lidia Giraudo, Giulia Cattaneo, Ilenia Iaia, Ymera Pignochino, Marco Basiricò, Elisa Vigna, Alberto Pisacane, Franca Fagioli, Soldano Ferrone, Massimo Aglietta, Gianpietro Dotti, Dario Sangiolo
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (23): 6321–6334.
https://doi.org/10.1158/1078-0432.CCR-20-0357
Published: 01 December 2020
View article titled, CSPG4-Specific CAR.CIK Lymphocytes as a Novel Therapy for the Treatment of Multiple Soft-Tissue Sarcoma Histotypes
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Includes: Multimedia, Supplementary data
Journal Articles

A Subset of Colorectal Cancers with Cross-Sensitivity to Olaparib and Oxaliplatin

Sabrina Arena, Giorgio Corti, Erika Durinikova, Monica Montone, Nicole M. Reilly, Mariangela Russo, Annalisa Lorenzato, Pamela Arcella, Luca Lazzari, Giuseppe Rospo, Massimiliano Pagani, Carlotta Cancelliere, Carola Negrino, Claudio Isella, Alice Bartolini, Andrea Cassingena, Alessio Amatu, Gianluca Mauri, Andrea Sartore-Bianchi, Gloria Mittica, Enzo Medico, Silvia Marsoni, Michael Linnebacher, Sergio Abrignani, Salvatore Siena, Federica Di Nicolantonio, Alberto Bardelli
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (6): 1372–1384.
https://doi.org/10.1158/1078-0432.CCR-19-2409
Published: 13 March 2020
View article titled, A Subset of Colorectal Cancers with Cross-Sensitivity to Olaparib and Oxaliplatin
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Includes: Supplementary data
Journal Articles

Patient-Derived Xenografts and Matched Cell Lines Identify Pharmacogenomic Vulnerabilities in Colorectal Cancer

Luca Lazzari, Giorgio Corti, Gabriele Picco, Claudio Isella, Monica Montone, Pamela Arcella, Erika Durinikova, Eugenia R. Zanella, Luca Novara, Fabiane Barbosa, Andrea Cassingena, Carlotta Cancelliere, Enzo Medico, Andrea Sartore-Bianchi, Salvatore Siena, Mathew J. Garnett, Andrea Bertotti, Livio Trusolino, Federica Di Nicolantonio, Michael Linnebacher, Alberto Bardelli, Sabrina Arena
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (20): 6243–6259.
https://doi.org/10.1158/1078-0432.CCR-18-3440
Published: 15 October 2019
View article titled, Patient-Derived Xenografts and Matched Cell Lines Identify Pharmacogenomic Vulnerabilities in Colorectal Cancer
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Includes: Supplementary data
Journal Articles

A Molecularly Annotated Model of Patient-Derived Colon Cancer Stem–Like Cells to Assess Genetic and Nongenetic Mechanisms of Resistance to Anti-EGFR Therapy

Paolo Luraghi, Viola Bigatto, Elia Cipriano, Gigliola Reato, Francesca Orzan, Francesco Sassi, Francesca De Bacco, Claudio Isella, Sara E. Bellomo, Enzo Medico, Paolo M. Comoglio, Andrea Bertotti, Livio Trusolino, Carla Boccaccio
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (4): 807–820.
https://doi.org/10.1158/1078-0432.CCR-17-2151
Published: 14 February 2018
View article titled, A Molecularly Annotated Model of Patient-Derived Colon Cancer Stem–Like Cells to Assess Genetic and Nongenetic Mechanisms of Resistance to Anti-EGFR Therapy
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Includes: Supplementary data
Journal Articles

Abstract IA09: Expression profiling of colorectal cancer PDX models for disease stratification and tumor-stroma interaction analysis

Enzo Medico
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16_Supplement): IA09.
https://doi.org/10.1158/1557-3265.PDX16-IA09
Published: 15 August 2016
View article titled, Abstract IA09: Expression profiling of colorectal cancer PDX models for disease stratification and tumor-stroma interaction analysis
Journal Articles

Genetic and Expression Analysis of MET, MACC1, and HGF in Metastatic Colorectal Cancer: Response to Met Inhibition in Patient Xenografts and Pathologic Correlations

Francesco Galimi, Davide Torti, Francesco Sassi, Claudio Isella, Davide Corà, Stefania Gastaldi, Dario Ribero, Andrea Muratore, Paolo Massucco, Dimitrios Siatis, Gianluca Paraluppi, Federica Gonella, Francesca Maione, Alberto Pisacane, Ezio David, Bruno Torchio, Mauro Risio, Mauro Salizzoni, Lorenzo Capussotti, Timothy Perera, Enzo Medico, Maria Flavia Di Renzo, Paolo M. Comoglio, Livio Trusolino, Andrea Bertotti
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (10): 3146–3156.
https://doi.org/10.1158/1078-0432.CCR-10-3377
Published: 15 May 2011
View article titled, Genetic and Expression Analysis of MET, MACC1, and HGF in Metastatic Colorectal Cancer: Response to Met Inhibition in Patient Xenografts and Pathologic Correlations
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Includes: Supplementary data
Journal Articles

Inhibition of Src Impairs the Growth of Met-Addicted Gastric Tumors

Andrea Bertotti, Cecilia Bracco, Flavia Girolami, Davide Torti, Stefania Gastaldi, Francesco Galimi, Enzo Medico, Paul Elvin, Paolo M. Comoglio, Livio Trusolino
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (15): 3933–3943.
https://doi.org/10.1158/1078-0432.CCR-10-0106
Published: 28 July 2010
View article titled, Inhibition of Src Impairs the Growth of Met-Addicted Gastric Tumors
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