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A Phase Ib/II Study of Sabizabulin, a Novel Oral Cytoskeleton Disruptor, in Men with Metastatic Castration-resistant Prostate Cancer with Progression on an Androgen Receptor–targeting Agent

Mark C. Markowski, Ronald Tutrone, Christopher Pieczonka, K. Gary Barnette, Robert H. Getzenberg, Domingo Rodriguez, Mitchell S. Steiner, Daniel R. Saltzstein, Mario A. Eisenberger, Emmanuel S. Antonarakis

Clin Cancer Res OF1–OF7.

DOI: https://doi.org/10.1158/1078-0432.CCR-22-0162

Published: 17 May 2022

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Includes: Supplementary data

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Circulating Tumor Cell Chromosomal Instability and Neuroendocrine Phenotype by Immunomorphology and Poor Outcomes in Men with mCRPC Treated with Abiraterone or Enzalutamide

Clin Cancer Res (2021) 27 (14): 4077–4088.

DOI: https://doi.org/10.1158/1078-0432.CCR-20-3471

Published: 15 July 2021

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Includes: Supplementary data

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A Randomized Phase II Study of Androgen Deprivation Therapy with or without Palbociclib in RB-positive Metastatic Hormone-Sensitive Prostate Cancer

Phillip L. Palmbos, Stephanie Daignault-Newton, Scott A. Tomlins, Neeraj Agarwal, Przemyslaw Twardowski, Alicia K. Morgans, Wm. Kevin Kelly, Vivek K. Arora, Emmanuel S. Antonarakis, Javed Siddiqui, Jon A. Jacobson, Matthew S. Davenport, Dan R. Robinson, Arul M. Chinnaiyan, Karen E. Knudsen, Maha Hussain

Clin Cancer Res (2021) 27 (11): 3017–3027.

DOI: https://doi.org/10.1158/1078-0432.CCR-21-0024

Published: 01 June 2021

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Randomized Phase II Trial of Sipuleucel-T with or without Radium-223 in Men with Bone-metastatic Castration-resistant Prostate Cancer

Catherine H. Marshall, Wei Fu, Hao Wang, Jong Chul Park, Theodore L. DeWeese, Phuoc T. Tran, Daniel Y. Song, Serina King, Michaella Afful, Julia Hurrelbrink, Charlotte Manogue, Patrick Cotogno, Nancy P. Moldawer, Pedro C. Barata, Charles G. Drake, Edwin M. Posadas, Andrew J. Armstrong, Oliver Sartor, Emmanuel S. Antonarakis

Clin Cancer Res (2021) 27 (6): 1623–1630.

DOI: https://doi.org/10.1158/1078-0432.CCR-20-4476

Published: 15 March 2021

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Includes: Supplementary data

Journal Articles

CDK12 Deficiency and the Immune Microenvironment in Prostate Cancer

Tamara L. Lotan, Emmanuel S. Antonarakis

Clin Cancer Res (2021) 27 (2): 380–382.

DOI: https://doi.org/10.1158/1078-0432.CCR-20-3877

Published: 19 January 2021

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Journal Articles

Reimagining Vaccines for Prostate Cancer: Back to the Future

Eugene Shenderov, Emmanuel S. Antonarakis

Clin Cancer Res (2020) 26 (19): 5056–5058.

DOI: https://doi.org/10.1158/1078-0432.CCR-20-2257

Published: 01 October 2020

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Journal Articles

Genomic and Clinicopathologic Characterization of ATM-deficient Prostate Cancer

Harsimar Kaur, Daniela C. Salles, Sanjana Murali, Jessica L. Hicks, Minh Nguyen, Colin C. Pritchard, Angelo M. De Marzo, Jerry S. Lanchbury, Bruce J. Trock, William B. Isaacs, Kirsten M. Timms, Emmanuel S. Antonarakis, Tamara L. Lotan

Clin Cancer Res (2020) 26 (18): 4869–4881.

DOI: https://doi.org/10.1158/1078-0432.CCR-20-0764

Published: 15 September 2020

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Includes: Supplementary data

Journal Articles

T-Cell Infiltration and Adaptive Treg Resistance in Response to Androgen Deprivation With or Without Vaccination in Localized Prostate Cancer

Aleksandar Z. Obradovic, Matthew C. Dallos, Marianna L. Zahurak, Alan W. Partin, Edward M. Schaeffer, Ashley E. Ross, Mohamad E. Allaf, Thomas R. Nirschl, David Liu, Carolyn G. Chapman, Tanya O'Neal, Haiyi Cao, Jennifer N. Durham, Gunes Guner, Javier A. Baena-Del Valle, Onur Ertunc, Angelo M. De Marzo, Emmanuel S. Antonarakis, Charles G. Drake

Clin Cancer Res (2020) 26 (13): 3182–3192.

DOI: https://doi.org/10.1158/1078-0432.CCR-19-3372

Published: 01 July 2020

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Includes: Supplementary data

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Clinical Significance of AR-V567es in Prostate Cancer—Response

Scott T. Tagawa, Emmanuel S. Antonarakis, Ada Gjyrezi, Giuseppe Galletti, Paraskevi Giannakakou

Clin Cancer Res (2019) 25 (19): 6010–6011.

DOI: https://doi.org/10.1158/1078-0432.CCR-19-1820

Published: 01 October 2019

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Journal Articles

Expression of AR-V7 and ARv^567es in Circulating Tumor Cells Correlates with Outcomes to Taxane Therapy in Men with Metastatic Prostate Cancer Treated in TAXYNERGY

Scott T. Tagawa, Emmanuel S. Antonarakis, Ada Gjyrezi, Giuseppe Galletti, Seaho Kim, Daniel Worroll, John Stewart, Atef Zaher, Ted P. Szatrowski, Karla V. Ballman, Katsuhiro Kita, Shinsuke Tasaki, Yang Bai, Luigi Portella, Brian J. Kirby, Fred Saad, Mario A. Eisenberger, David M. Nanus, Paraskevi Giannakakou

Clin Cancer Res (2019) 25 (6): 1880–1888.

DOI: https://doi.org/10.1158/1078-0432.CCR-18-0320

Published: 15 March 2019

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Includes: Supplementary data

Journal Articles

Antigen-Specific CD8 Lytic Phenotype Induced by Sipuleucel-T in Hormone-Sensitive or Castration-Resistant Prostate Cancer and Association with Overall Survival

Emmanuel S. Antonarakis, Eric J. Small, Daniel P. Petrylak, David I. Quinn, Adam S. Kibel, Nancy N. Chang, Erica Dearstyne, Matt Harmon, Dwayne Campogan, Heather Haynes, Tuyen Vu, Nadeem A. Sheikh, Charles G. Drake

Clin Cancer Res (2018) 24 (19): 4662–4671.

DOI: https://doi.org/10.1158/1078-0432.CCR-18-0638

Published: 01 October 2018

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Includes: Supplementary data

Journal Articles

Muscadine Grape Skin Extract (MPX) in Men with Biochemically Recurrent Prostate Cancer: A Randomized, Multicenter, Placebo-Controlled Clinical Trial

Clin Cancer Res (2018) 24 (2): 306–315.

DOI: https://doi.org/10.1158/1078-0432.CCR-17-1100

Published: 15 January 2018

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Includes: Supplementary data

Journal Articles

MSH2 Loss in Primary Prostate Cancer

Liana B. Guedes, Emmanuel S. Antonarakis, Michael T. Schweizer, Nooshin Mirkheshti, Fawaz Almutairi, Jong Chul Park, Stephanie Glavaris, Jessica Hicks, Mario A. Eisenberger, Angelo M. De Marzo, Jonathan I. Epstein, William B. Isaacs, James R. Eshleman, Colin C. Pritchard, Tamara L. Lotan

Clin Cancer Res (2017) 23 (22): 6863–6874.

DOI: https://doi.org/10.1158/1078-0432.CCR-17-0955

Published: 14 November 2017

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Includes: Supplementary data

Journal Articles

Safety and Antitumor Activity of Apalutamide (ARN-509) in Metastatic Castration-Resistant Prostate Cancer with and without Prior Abiraterone Acetate and Prednisone

Dana E. Rathkopf, Emmanuel S. Antonarakis, Neal D. Shore, Ronald F. Tutrone, Joshi J. Alumkal, Charles J. Ryan, Mansoor Saleh, Ralph J. Hauke, Rajesh Bandekar, Edna Chow Maneval, Carla J. de Boer, Margaret K. Yu, Howard I. Scher

Clin Cancer Res (2017) 23 (14): 3544–3551.

DOI: https://doi.org/10.1158/1078-0432.CCR-16-2509

Published: 13 July 2017

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Includes: Supplementary data

Journal Articles

Sequencing of Sipuleucel-T and Androgen Deprivation Therapy in Men with Hormone-Sensitive Biochemically Recurrent Prostate Cancer: A Phase II Randomized Trial

Emmanuel S. Antonarakis, Adam S. Kibel, Evan Y. Yu, Lawrence I. Karsh, Aymen Elfiky, Neal D. Shore, Nicholas J. Vogelzang, John M. Corman, Frederick E. Millard, Johnathan C. Maher, Nancy N. Chang, Todd DeVries, Nadeem A. Sheikh, Charles G. Drake

Clin Cancer Res (2017) 23 (10): 2451–2459.

DOI: https://doi.org/10.1158/1078-0432.CCR-16-1780

Published: 14 May 2017

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Includes: Supplementary data

Journal Articles

Analytic Validation of RNA In Situ Hybridization (RISH) for AR and AR-V7 Expression in Human Prostate Cancer

Liana B. Guedes, Carlos L. Morais, Fawaz Almutairi, Michael C. Haffner, Qizhi Zheng, John T. Isaacs, Emmanuel S. Antonarakis, Changxue Lu, Harrison Tsai, Jun Luo, Angelo M. De Marzo, Tamara L. Lotan

Clin Cancer Res (2016) 22 (18): 4651–4663.

DOI: https://doi.org/10.1158/1078-0432.CCR-16-0205

Published: 15 September 2016

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Includes: Supplementary data

Journal Articles

Lenalidomide in Nonmetastatic Biochemically Relapsed Prostate Cancer: Results of a Phase I/II Double-Blinded, Randomized Study

Daniel Keizman, Marianna Zahurak, Victoria Sinibaldi, Michael Carducci, Samuel Denmeade, Charles Drake, Roberto Pili, Emmanuel S. Antonarakis, Susan Hudock, Mario Eisenberger

Clin Cancer Res (2010) 16 (21): 5269–5276.

DOI: https://doi.org/10.1158/1078-0432.CCR-10-1928

Published: 31 October 2010

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NARROW

A Phase Ib/II Study of Sabizabulin, a Novel Oral Cytoskeleton Disruptor, in Men with Metastatic Castration-resistant Prostate Cancer with Progression on an Androgen Receptor–targeting Agent

Circulating Tumor Cell Chromosomal Instability and Neuroendocrine Phenotype by Immunomorphology and Poor Outcomes in Men with mCRPC Treated with Abiraterone or Enzalutamide

A Randomized Phase II Study of Androgen Deprivation Therapy with or without Palbociclib in RB-positive Metastatic Hormone-Sensitive Prostate Cancer

Randomized Phase II Trial of Sipuleucel-T with or without Radium-223 in Men with Bone-metastatic Castration-resistant Prostate Cancer

CDK12 Deficiency and the Immune Microenvironment in Prostate Cancer

Reimagining Vaccines for Prostate Cancer: Back to the Future

Genomic and Clinicopathologic Characterization of ATM-deficient Prostate Cancer

T-Cell Infiltration and Adaptive Treg Resistance in Response to Androgen Deprivation With or Without Vaccination in Localized Prostate Cancer

Clinical Significance of AR-V567es in Prostate Cancer—Response

Expression of AR-V7 and ARv^567es in Circulating Tumor Cells Correlates with Outcomes to Taxane Therapy in Men with Metastatic Prostate Cancer Treated in TAXYNERGY

Antigen-Specific CD8 Lytic Phenotype Induced by Sipuleucel-T in Hormone-Sensitive or Castration-Resistant Prostate Cancer and Association with Overall Survival

Muscadine Grape Skin Extract (MPX) in Men with Biochemically Recurrent Prostate Cancer: A Randomized, Multicenter, Placebo-Controlled Clinical Trial

MSH2 Loss in Primary Prostate Cancer

Safety and Antitumor Activity of Apalutamide (ARN-509) in Metastatic Castration-Resistant Prostate Cancer with and without Prior Abiraterone Acetate and Prednisone

Sequencing of Sipuleucel-T and Androgen Deprivation Therapy in Men with Hormone-Sensitive Biochemically Recurrent Prostate Cancer: A Phase II Randomized Trial

Analytic Validation of RNA In Situ Hybridization (RISH) for AR and AR-V7 Expression in Human Prostate Cancer

Lenalidomide in Nonmetastatic Biochemically Relapsed Prostate Cancer: Results of a Phase I/II Double-Blinded, Randomized Study

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