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E. Antonio Chiocca
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Journal Articles

Pilot Trial of Perampanel on Peritumoral Hyperexcitability in Newly Diagnosed High-grade Glioma

Steven Tobochnik, Michael S. Regan, Maria K.C. Dorotan, Dustine Reich, Emily Lapinskas, Md Amin Hossain, Sylwia Stopka, David M. Meredith, Sandro Santagata, Melissa M. Murphy, Omar Arnaout, Wenya Linda Bi, E. Antonio Chiocca, Alexandra J. Golby, Michael A. Mooney, Timothy R. Smith, Keith L. Ligon, Patrick Y. Wen, Nathalie Y.R. Agar, Jong Woo Lee
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (23): 5365–5373.
https://doi.org/10.1158/1078-0432.CCR-24-1849
Published: 02 December 2024
View article titled, Pilot Trial of Perampanel on Peritumoral Hyperexcitability in Newly Diagnosed High-grade Glioma
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Includes: Supplementary data
Journal Articles

Clinical Importance of the lncRNA NEAT1 in Cancer Patients Treated with Immune Checkpoint Inhibitors

Joseph Toker, J. Bryan Iorgulescu, Alexander L. Ling, Genaro R. Villa, Josephina A.M.A. Gadet, Laxmi Parida, Gad Getz, Catherine J. Wu, David A. Reardon, E. Antonio Chiocca, Marco Mineo
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (12): 2226–2238.
https://doi.org/10.1158/1078-0432.CCR-22-3714
Published: 13 June 2023
View article titled, Clinical Importance of the lncRNA <em>NEAT1</em> in Cancer Patients Treated with Immune Checkpoint Inhibitors
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Includes: Supplementary data
Journal Articles

NOTCH-Induced MDSC Recruitment after oHSV Virotherapy in CNS Cancer Models Modulates Antitumor Immunotherapy

Yoshihiro Otani, Ji Young Yoo, Cole T. Lewis, Samantha Chao, Jessica Swanner, Toshihiko Shimizu, Jin Muk Kang, Sara A. Murphy, Kimberly Rivera-Caraballo, Bangxing Hong, Joseph C. Glorioso, Hiroshi Nakashima, Sean E. Lawler, Yeshavanth Banasavadi-Siddegowda, John D. Heiss, Yuanqing Yan, Guangsheng Pei, Michael A. Caligiuri, Zhongming Zhao, E. Antonio Chiocca, Jianhua Yu, Balveen Kaur
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (7): 1460–1473.
https://doi.org/10.1158/1078-0432.CCR-21-2347
Published: 01 April 2022
View article titled, NOTCH-Induced MDSC Recruitment after oHSV Virotherapy in CNS Cancer Models Modulates Antitumor Immunotherapy
Open the PDF for NOTCH-Induced MDSC Recruitment after oHSV Virotherapy in CNS Cancer Models Modulates Antitumor Immunotherapy in another window
Includes: Supplementary data
Journal Articles

Concurrent Dexamethasone Limits the Clinical Benefit of Immune Checkpoint Blockade in Glioblastoma

J. Bryan Iorgulescu, Prafulla C. Gokhale, Maria C. Speranza, Benjamin K. Eschle, Michael J. Poitras, Margaret K. Wilkens, Kara M. Soroko, Chhayheng Chhoeu, Aine Knott, Yan Gao, Mary Jane Lim-Fat, Gregory J. Baker, Dennis M. Bonal, Quang-Dé Nguyen, Gareth R. L. Grant, Keith L. Ligon, Peter K. Sorger, E. Antonio Chiocca, Ana C. Anderson, Paul T. Kirschmeier, Arlene H. Sharpe, Gordon J. Freeman, David A. Reardon
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (1): 276–287.
https://doi.org/10.1158/1078-0432.CCR-20-2291
Published: 04 January 2021
View article titled, Concurrent Dexamethasone Limits the Clinical Benefit of Immune Checkpoint Blockade in Glioblastoma
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Includes: Supplementary data
Journal Articles

Cytomegalovirus Encephalopathy during Brain Tumor Irradiation

Sean E. Lawler, E. Antonio Chiocca, Charles H. Cook
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (13): 3077–3078.
https://doi.org/10.1158/1078-0432.CCR-20-0646
Published: 01 July 2020
View article titled, Cytomegalovirus Encephalopathy during Brain Tumor Irradiation
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Journal Articles

Correction: Arming an Oncolytic Herpes Simplex Virus Type 1 with a Single-chain Fragment Variable Antibody against PD-1 for Experimental Glioblastoma Therapy

Carmela Passaro, Quazim Alayo, Isabel DeLaura, John McNulty, Korneel Grauwet, Hirotaka Ito, Vivek Bhaskaran, Marco Mineo, Sean E. Lawler, Khalid Shah, Maria C. Speranza, William Goins, Eric McLaughlin, Soledad Fernandez, David A. Reardon, Gordon J. Freeman, E. Antonio Chiocca, Hiroshi Nakashima
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (3): 758.
https://doi.org/10.1158/1078-0432.CCR-19-4091
Published: 03 February 2020
View article titled, Correction: Arming an Oncolytic Herpes Simplex Virus Type 1 with a Single-chain Fragment Variable Antibody against PD-1 for Experimental Glioblastoma Therapy
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Journal Articles

Arming an Oncolytic Herpes Simplex Virus Type 1 with a Single-chain Fragment Variable Antibody against PD-1 for Experimental Glioblastoma Therapy

Carmela Passaro, Quazim Alayo, Isabel DeLaura, John McNulty, Korneel Grauwet, Hirotaka Ito, Vivek Bhaskaran, Marco Mineo, Sean E. Lawler, Khalid Shah, Maria C. Speranza, William Goins, Eric McLaughlin, Soledad Fernandez, David A. Reardon, Gordon J. Freeman, E. Antonio Chiocca, Hiroshi Nakashima
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (1): 290–299.
https://doi.org/10.1158/1078-0432.CCR-18-2311
Published: 03 January 2019
View article titled, Arming an Oncolytic Herpes Simplex Virus Type 1 with a Single-chain Fragment Variable Antibody against PD-1 for Experimental Glioblastoma Therapy
Open the PDF for Arming an Oncolytic Herpes Simplex Virus Type 1 with a Single-chain Fragment Variable Antibody against PD-1 for Experimental Glioblastoma Therapy in another window
Includes: Supplementary data
Journal Articles

Toxicity and Efficacy of a Novel GADD34-expressing Oncolytic HSV-1 for the Treatment of Experimental Glioblastoma

Hiroshi Nakashima, Tran Nguyen, Kazue Kasai, Carmela Passaro, Hirotaka Ito, William F. Goins, Imran Shaikh, Ronald Erdelyi, Reiko Nishihara, Ichiro Nakano, David A. Reardon, Ana C. Anderson, Vijay Kuchroo, E. Antonio Chiocca
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (11): 2574–2584.
https://doi.org/10.1158/1078-0432.CCR-17-2954
Published: 31 May 2018
View article titled, Toxicity and Efficacy of a Novel GADD34-expressing Oncolytic HSV-1 for the Treatment of Experimental Glioblastoma
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Includes: Supplementary data
Journal Articles

Development of a Function-Blocking Antibody Against Fibulin-3 as a Targeted Reagent for Glioblastoma

Mohan S. Nandhu, Prajna Behera, Vivek Bhaskaran, Sharon L. Longo, Lina M. Barrera-Arenas, Sadhak Sengupta, Diego J. Rodriguez-Gil, E. Antonio Chiocca, Mariano S. Viapiano
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (4): 821–833.
https://doi.org/10.1158/1078-0432.CCR-17-1628
Published: 14 February 2018
View article titled, Development of a Function-Blocking Antibody Against Fibulin-3 as a Targeted Reagent for Glioblastoma
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Includes: Supplementary data
Journal Articles

DNA Demethylating Agents Synergize with Oncolytic HSV1 against Malignant Gliomas

Kazuo Okemoto, Kazue Kasai, Benjamin Wagner, Amy Haseley, Hans Meisen, Chelsea Bolyard, Xiaokui Mo, Allison Wehr, Amy Lehman, Soledad Fernandez, Balveen Kaur, E. Antonio Chiocca
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (21): 5952–5959.
https://doi.org/10.1158/1078-0432.CCR-12-3588
Published: 31 October 2013
View article titled, DNA Demethylating Agents Synergize with Oncolytic HSV1 against Malignant Gliomas
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Includes: Supplementary data
Journal Articles

Copper Chelation Enhances Antitumor Efficacy and Systemic Delivery of Oncolytic HSV

Ji Young Yoo, Jason Pradarelli, Amy Haseley, Jeffrey Wojton, Azeem Kaka, Anna Bratasz, Christopher A. Alvarez-Breckenridge, Jun-Ge Yu, Kimerly Powell, Andrew P. Mazar, Theodoros N. Teknos, E. Antonio Chiocca, Joseph C. Glorioso, Matthew Old, Balveen Kaur
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (18): 4931–4941.
https://doi.org/10.1158/1078-0432.CCR-12-0697
Published: 16 September 2012
View article titled, Copper Chelation Enhances Antitumor Efficacy and Systemic Delivery of Oncolytic HSV
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Includes: Supplementary data
Journal Articles

Chondroitinase ABC I–Mediated Enhancement of Oncolytic Virus Spread and Antitumor Efficacy

Nina Dmitrieva, Lianbo Yu, Mariano Viapiano, Timothy P. Cripe, E. Antonio Chiocca, Joseph C. Glorioso, Balveen Kaur
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (6): 1362–1372.
https://doi.org/10.1158/1078-0432.CCR-10-2213
Published: 15 March 2011
View article titled, Chondroitinase ABC I–Mediated Enhancement of Oncolytic Virus Spread and Antitumor Efficacy
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Includes: Supplementary data