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Douglas S. Hawkins
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Journal Articles

National Cancer Institute Combination Therapy Platform Trial with Molecular Analysis for Therapy Choice (ComboMATCH)

Open Access
Funda Meric-Bernstam, James M. Ford, Peter J. O'Dwyer, Geoffrey I. Shapiro, Lisa M. McShane, Boris Freidlin, Roisin E. O'Cearbhaill, Suzanne George, Julia Glade-Bender, Gary H. Lyman, James V. Tricoli, David Patton, Stanley R. Hamilton, Robert J. Gray, Douglas S. Hawkins, Bhanumati Ramineni, Keith T. Flaherty, Petros Grivas, Timothy A. Yap, Jordan Berlin, James H. Doroshow, Lyndsay N. Harris, Jeffrey A. Moscow
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (8): 1412–1422.
https://doi.org/10.1158/1078-0432.CCR-22-3334
Published: 14 April 2023
View article titled, National Cancer Institute Combination Therapy Platform Trial with Molecular Analysis for Therapy Choice (ComboMATCH)
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Includes: Supplementary data
Journal Articles

Predicting Molecular Subtype and Survival of Rhabdomyosarcoma Patients Using Deep Learning of H&E Images: A Report from the Children's Oncology Group

Open Access
David Milewski, Hyun Jung, G. Thomas Brown, Yanling Liu, Ben Somerville, Curtis Lisle, Marc Ladanyi, Erin R. Rudzinski, Hyoyoung Choo-Wosoba, Donald A. Barkauskas, Tammy Lo, David Hall, Corinne M. Linardic, Jun S. Wei, Hsien-Chao Chou, Stephen X. Skapek, Rajkumar Venkatramani, Peter K. Bode, Seth M. Steinberg, George Zaki, Igor B. Kuznetsov, Douglas S. Hawkins, Jack F. Shern, Jack Collins, Javed Khan
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (2): 364–378.
https://doi.org/10.1158/1078-0432.CCR-22-1663
Published: 17 January 2023
View article titled, Predicting Molecular Subtype and Survival of Rhabdomyosarcoma Patients Using Deep Learning of H&E Images: A Report from the Children's Oncology Group
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Includes: Supplementary data
Journal Articles

Abstract A55: Circulating tumor DNA in newly diagnosed intermediate-risk rhabdomyosarcoma

Free
Samuel Abbou, David Hall, Donald A. Barkauskas, Kelly Klega, Anwesha Nag, Aaron R. Thorner, Mark Krailo, Steven Dubois, Douglas S. Hawkins, Brian D. Crompton
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (11_Supplement): A55.
https://doi.org/10.1158/1557-3265.LiqBiop20-A55
Published: 01 June 2020
View article titled, Abstract A55: Circulating tumor DNA in newly diagnosed intermediate-risk rhabdomyosarcoma
Journal Articles

Broad Spectrum Activity of the Checkpoint Kinase 1 Inhibitor Prexasertib as a Single Agent or Chemopotentiator Across a Range of Preclinical Pediatric Tumor Models

Free
Caitlin D. Lowery, Michele Dowless, Matthew Renschler, Wayne Blosser, Alle B. VanWye, Jennifer R. Stephens, Philip W. Iversen, Aimee Bence Lin, Richard P. Beckmann, Kateryna Krytska, Kristina A. Cole, John M. Maris, Douglas S. Hawkins, Brian P. Rubin, Raushan T. Kurmasheva, Peter J. Houghton, Richard Gorlick, E. Anders Kolb, Min H. Kang, C. Patrick Reynolds, Stephen W. Erickson, Beverly A. Teicher, Malcolm A. Smith, Louis F. Stancato
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (7): 2278–2289.
https://doi.org/10.1158/1078-0432.CCR-18-2728
Published: 01 April 2019
View article titled, Broad Spectrum Activity of the Checkpoint Kinase 1 Inhibitor Prexasertib as a Single Agent or Chemopotentiator Across a Range of Preclinical Pediatric Tumor Models
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Includes: Supplementary data
Journal Articles

Undifferentiated Sarcomas in Children Harbor Clinically Relevant Oncogenic Fusions and Gene Copy-Number Alterations: A Report from the Children's Oncology Group

Free
Theodore W. Laetsch, Angshumoy Roy, Lin Xu, Jennifer O. Black, Cheryl M. Coffin, Yueh-Yun Chi, Jing Tian, Sheri L. Spunt, Douglas S. Hawkins, Julia A. Bridge, D. Williams Parsons, Stephen X. Skapek
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (16): 3888–3897.
https://doi.org/10.1158/1078-0432.CCR-18-0672
Published: 14 August 2018
View article titled, Undifferentiated Sarcomas in Children Harbor Clinically Relevant Oncogenic Fusions and Gene Copy-Number Alterations: A Report from the Children's Oncology Group
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Includes: Supplementary data
Journal Articles

Impact of Two Measures of Micrometastatic Disease on Clinical Outcomes in Patients with Newly Diagnosed Ewing Sarcoma: A Report from the Children's Oncology Group

Free
Kieuhoa T. Vo, Jeremy V. Edwards, C. Lorrie Epling, Elizabeth Sinclair, Douglas S. Hawkins, Holcombe E. Grier, Katherine A. Janeway, Phillip Barnette, Elizabeth McIlvaine, Mark D. Krailo, Donald A. Barkauskas, Katherine K. Matthay, Richard B. Womer, Richard G. Gorlick, Stephen L. Lessnick, Crystal L. Mackall, Steven G. DuBois
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (14): 3643–3650.
https://doi.org/10.1158/1078-0432.CCR-15-2516
Published: 14 July 2016
View article titled, Impact of Two Measures of Micrometastatic Disease on Clinical Outcomes in Patients with Newly Diagnosed Ewing Sarcoma: A Report from the Children's Oncology Group
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Includes: Supplementary data
Journal Articles

Clinical Application of Prognostic Gene Expression Signature in Fusion Gene–Negative Rhabdomyosarcoma: A Report from the Children's Oncology Group

Free
Pooja Hingorani, Edoardo Missiaglia, Janet Shipley, James R. Anderson, Timothy J. Triche, Mauro Delorenzi, Julie Gastier-Foster, Michele Wing, Douglas S. Hawkins, Stephen X. Skapek
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (20): 4733–4739.
https://doi.org/10.1158/1078-0432.CCR-14-3326
Published: 14 October 2015
View article titled, Clinical Application of Prognostic Gene Expression Signature in Fusion Gene–Negative Rhabdomyosarcoma: A Report from the Children's Oncology Group
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Includes: Supplementary data
Journal Articles

Inhaled Granulocyte-Macrophage Colony Stimulating Factor for First Pulmonary Recurrence of Osteosarcoma: Effects on Disease-Free Survival and Immunomodulation. A Report From the Children's Oncology Group

Free
Carola A.S. Arndt, Nadya V. Koshkina, Carrie Y. Inwards, Douglas S. Hawkins, Mark D. Krailo, Doojduen Villaluna, Peter M. Anderson, Allen M. Goorin, Martin L. Blakely, Mark Bernstein, Sharon A. Bell, Kaylee Ray, Darryl C. Grendahl, Neyssa Marina, Eugenie S. Kleinerman
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (15): 4024–4030.
https://doi.org/10.1158/1078-0432.CCR-10-0662
Published: 28 July 2010
View article titled, Inhaled Granulocyte-Macrophage Colony Stimulating Factor for First Pulmonary Recurrence of Osteosarcoma: Effects on Disease-Free Survival and Immunomodulation. A Report From the Children's Oncology Group
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Journal Articles

Randomized Trial and Pharmacokinetic Study of Pegfilgrastim versus Filgrastim after Dose-Intensive Chemotherapy in Young Adults and Children with Sarcomas

Free
Elizabeth Fox, Brigitte C. Widemann, Douglas S. Hawkins, Nalini Jayaprakash, Ramzi Dagher, Alberta A. Aikin, Donna Bernstein, Lauren Long, Crystal Mackall, Lee Helman, Seth M. Steinberg, Frank M. Balis
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (23): 7361–7367.
https://doi.org/10.1158/1078-0432.CCR-09-0761
Published: 30 November 2009
View article titled, Randomized Trial and Pharmacokinetic Study of Pegfilgrastim versus Filgrastim after Dose-Intensive Chemotherapy in Young Adults and Children with Sarcomas
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Journal Articles

Phase II Trial of Oral Aminopterin for Adults and Children with Refractory Acute Leukemia

Free
Peter D. Cole, Richard A. Drachtman, Angela K. Smith, Sarah Cate, Richard A. Larson, Douglas S. Hawkins, John Holcenberg, Kara Kelly, Barton A. Kamen
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (22): 8089–8096.
https://doi.org/10.1158/1078-0432.CCR-05-0355
Published: 18 November 2005
View article titled, Phase II Trial of Oral Aminopterin for Adults and Children with Refractory Acute Leukemia
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Journal Articles

Asparaginase Pharmacokinetics After Intensive Polyethylene Glycol-Conjugated L-Asparaginase Therapy for Children with Relapsed Acute Lymphoblastic Leukemia

Free
Douglas S. Hawkins, Julie R. Park, Blythe G. Thomson, Judy L. Felgenhauer, John S. Holcenberg, Eduard H. Panosyan, Vassilios I. Avramis
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (16): 5335–5341.
https://doi.org/10.1158/1078-0432.CCR-04-0222
Published: 24 August 2004
View article titled, Asparaginase Pharmacokinetics After Intensive Polyethylene Glycol-Conjugated L-Asparaginase Therapy for Children with Relapsed Acute Lymphoblastic Leukemia
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