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Journal Articles

Phase II Multi-institutional Clinical Trial Result of Concurrent Cetuximab and Nivolumab in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma

Clin Cancer Res (2022) 28 (11): 2329–2338.

DOI: https://doi.org/10.1158/1078-0432.CCR-21-3849

Published: 01 June 2022

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Includes: Supplementary data

Journal Articles

Phase Ib Study of Chemoprevention with Green Tea Polyphenon E and Erlotinib in Patients with Advanced Premalignant Lesions (APL) of the Head and Neck

Dong M. Shin, Sreenivas Nannapaneni, Mihir R. Patel, Qiuying Shi, Yuan Liu, Zhengjia Chen, Amy Y. Chen, Mark W. El-Deiry, Jonathan J. Beitler, Conor E. Steuer, Steven M. Roser, Adam M. Klein, Taofeek K. Owonikoko, Suresh S. Ramalingam, Fadlo R. Khuri, Zhuo G. Chen, Nabil F. Saba

Clin Cancer Res (2020) 26 (22): 5860–5868.

DOI: https://doi.org/10.1158/1078-0432.CCR-20-2276

Published: 13 November 2020

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Includes: Supplementary data

Journal Articles

Editor's Note: The Pivotal Role of Integrin β1 in Metastasis of Head and Neck Squamous Cell Carcinoma

Dongsheng Wang, Susan Müller, A.R.M. Ruhul Amin, Donghai Huang, Ling Su, Zhongliang Hu, Mohammad Aminur Rahman, Sreenivas Nannapaneni, Lydia Koenig, Zhengjia Chen, Mourad Tighiouart, Dong M. Shin, Zhuo G. Chen

Clin Cancer Res (2020) 26 (18): 5052.

DOI: https://doi.org/10.1158/1078-0432.CCR-20-3175

Published: 15 September 2020

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Journal Articles

Honokiol Radiosensitizes Squamous Cell Carcinoma of the Head and Neck by Downregulation of Survivin

Xu Wang, Jonathan J. Beitler, Wen Huang, Guo Chen, Guoqing Qian, Kelly Magliocca, Mihir R. Patel, Amy Y. Chen, Jun Zhang, Sreenivas Nannapaneni, Sungjin Kim, Zhengjia Chen, Xingming Deng, Nabil F. Saba, Zhuo Georgia Chen, Jack L. Arbiser, Dong M. Shin

Clin Cancer Res (2018) 24 (4): 858–869.

DOI: https://doi.org/10.1158/1078-0432.CCR-17-0345

Published: 14 February 2018

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Includes: Supplementary data

Journal Articles

HER3 Targeting Sensitizes HNSCC to Cetuximab by Reducing HER3 Activity and HER2/HER3 Dimerization: Evidence from Cell Line and Patient-Derived Xenograft Models

Dongsheng Wang, Guoqing Qian, Hongzheng Zhang, Kelly R. Magliocca, Sreenivas Nannapaneni, A.R.M. Ruhul Amin, Michael Rossi, Mihir Patel, Mark El-Deiry, J. Trad Wadsworth, Zhengjia Chen, Fadlo R. Khuri, Dong M. Shin, Nabil F. Saba, Zhuo G. Chen

Clin Cancer Res (2017) 23 (3): 677–686.

DOI: https://doi.org/10.1158/1078-0432.CCR-16-0558

Published: 31 January 2017

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Includes: Supplementary data

Journal Articles

CCR 20^th Anniversary Commentary: Prospects and Challenges of Therapeutic Nanoparticles in Cancer

Mohammad Aminur Rahman, Dong M. Shin

Clin Cancer Res (2015) 21 (20): 4499–4501.

DOI: https://doi.org/10.1158/1078-0432.CCR-14-3126

Published: 14 October 2015

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Journal Articles

Phase II Study of Cetuximab in Combination with Cisplatin and Radiation in Unresectable, Locally Advanced Head and Neck Squamous Cell Carcinoma: Eastern Cooperative Oncology Group Trial E3303

Ann Marie Egloff, Ju-Whei Lee, Corey J. Langer, Harry Quon, Alec Vaezi, Jennifer R. Grandis, Raja R. Seethala, Lin Wang, Dong M. Shin, Athanassios Argiris, Donghua Yang, Ranee Mehra, John Andrew Ridge, Urjeet A. Patel, Barbara A. Burtness, Arlene A. Forastiere

Clin Cancer Res (2014) 20 (19): 5041–5051.

DOI: https://doi.org/10.1158/1078-0432.CCR-14-0051

Published: 30 September 2014

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Includes: Supplementary data

Journal Articles

RRM2 Regulates Bcl-2 in Head and Neck and Lung Cancers: A Potential Target for Cancer Therapy

Mohammad Aminur Rahman, A.R.M. Ruhul Amin, Dongsheng Wang, Lydia Koenig, Sreenivas Nannapaneni, Zhengjia Chen, Zhibo Wang, Gabriel Sica, Xingming Deng, Zhuo (Georgia) Chen, Dong M. Shin

Clin Cancer Res (2013) 19 (13): 3416–3428.

DOI: https://doi.org/10.1158/1078-0432.CCR-13-0073

Published: 30 June 2013

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Includes: Supplementary data

Journal Articles

Chemoprevention of Head and Neck Cancer by Simultaneous Blocking of Epidermal Growth Factor Receptor and Cyclooxygenase-2 Signaling Pathways: Preclinical and Clinical Studies

Clin Cancer Res (2013) 19 (5): 1244–1256.

DOI: https://doi.org/10.1158/1078-0432.CCR-12-3149

Published: 03 March 2013

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Includes: Supplementary data

Journal Articles

The Pivotal Role of Integrin β1 in Metastasis of Head and Neck Squamous Cell Carcinoma

Clin Cancer Res (2012) 18 (17): 4589–4599.

DOI: https://doi.org/10.1158/1078-0432.CCR-11-3127

Published: 30 August 2012

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Includes: Supplementary data

Journal Articles

Therapeutic Nanoparticles for Drug Delivery in Cancer

Kwangjae Cho, Xu Wang, Shuming Nie, Zhuo (Georgia) Chen, Dong M. Shin

Clin Cancer Res (2008) 14 (5): 1310–1316.

DOI: https://doi.org/10.1158/1078-0432.CCR-07-1441

Published: 03 March 2008

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Journal Articles

Phase I Clinical and Pharmacodynamic Evaluation of Oral CI-1033 in Patients with Refractory Cancer

Ralph G. Zinner, John Nemunaitis, Irene Eiseman, Hyung Ju C. Shin, Stephen C. Olson, James Christensen, Xin Huang, Peter F. Lenehan, Nicholas J. Donato, Dong M. Shin

Clin Cancer Res (2007) 13 (10): 3006–3014.

DOI: https://doi.org/10.1158/1078-0432.CCR-06-1958

Published: 15 May 2007

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Journal Articles

Enhancement of Docetaxel-Induced Cytotoxicity by Blocking Epidermal Growth Factor Receptor and Cyclooxygenase-2 Pathways in Squamous Cell Carcinoma of the Head and Neck

Mi Sun Choe, Zhuo Chen, Carmen M. Klass, Xin Zhang, Dong M. Shin

Clin Cancer Res (2007) 13 (10): 3015–3023.

DOI: https://doi.org/10.1158/1078-0432.CCR-06-2959

Published: 15 May 2007

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Journal Articles

Progress in Chemoprevention Drug Development: The Promise of Molecular Biomarkers for Prevention of Intraepithelial Neoplasia and Cancer—A Plan to Move Forward

Clin Cancer Res (2006) 12 (12): 3661–3697.

DOI: https://doi.org/10.1158/1078-0432.CCR-06-1104

Published: 15 June 2006

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Journal Articles

Fenretinide Activity in Retinoid-Resistant Oral Leukoplakia

Scott M. Lippman, J. Jack Lee, Jack W. Martin, Adel K. El-Naggar, Xiaochun Xu, Dong M. Shin, Margaret Thomas, Li Mao, Herbert A. Fritsche, Jr., Xian Zhou, Vassiliki Papadimitrakopoulou, Fadlo R. Khuri, Hai Tran, Gary L. Clayman, Walter N. Hittelman, Waun Ki Hong, Reuben Lotan

Clin Cancer Res (2006) 12 (10): 3109–3114.

DOI: https://doi.org/10.1158/1078-0432.CCR-05-2636

Published: 17 May 2006

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Journal Articles

Tumor Growth Inhibition by Simultaneously Blocking Epidermal Growth Factor Receptor and Cyclooxygenase-2 in a Xenograft Model

Xin Zhang, Zhuo (Georgia) Chen, Mi Sun Choe, Yan Lin, Shi-Yong Sun, H. Samuel Wieand, Hyung Ju C. Shin, Amy Chen, Fadlo R. Khuri, Dong M. Shin

Clin Cancer Res (2005) 11 (17): 6261–6269.

DOI: https://doi.org/10.1158/1078-0432.CCR-04-2102

Published: 06 September 2005

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Journal Articles

Phase 1 Clinical and Pharmacokinetics Evaluation of Oral CI-1033 in Patients with Refractory Cancer

John Nemunaitis, Irene Eiseman, Casey Cunningham, Neil Senzer, Adrienne Williams, Peter F. Lenehan, Stephen C. Olson, Paul Bycott, Michael Schlicht, Rebecca Zentgraff, Dong M. Shin, Ralph G. Zinner

Clin Cancer Res (2005) 11 (10): 3846–3853.

DOI: https://doi.org/10.1158/1078-0432.CCR-04-1950

Published: 16 May 2005

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Journal Articles

Correlation of Protease-Activated Receptor-1 With Differentiation Markers in Squamous Cell Carcinoma of the Head and Neck and Its Implication in Lymph Node Metastasis

Xin Zhang, Jennifer L. Hunt, Doug P. Landsittel, Susan Muller, Karen Adler-Storthz, Robert L. Ferris, Dong M. Shin, Zhuo (Georgia) Chen

Clin Cancer Res (2004) 10 (24): 8451–8459.

DOI: https://doi.org/10.1158/1078-0432.CCR-04-0546

Published: 28 December 2004

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Journal Articles

Simultaneously Targeting Epidermal Growth Factor Receptor Tyrosine Kinase and Cyclooxygenase-2, an Efficient Approach to Inhibition of Squamous Cell Carcinoma of the Head and Neck

Zhuo (Georgia) Chen, Xin Zhang, Mengfeng Li, Zhiqiang Wang, H. Samuel Wieand, Jennifer R. Grandis, Dong M. Shin

Clin Cancer Res (2004) 10 (17): 5930–5939.

DOI: https://doi.org/10.1158/1078-0432.CCR-03-0677

Published: 08 September 2004

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Journal Articles

Phase I Study of the Farnesyltransferase Inhibitor Lonafarnib with Paclitaxel in Solid Tumors

Clin Cancer Res (2004) 10 (9): 2968–2976.

DOI: https://doi.org/10.1158/1078-0432.CCR-03-0412

Published: 06 May 2004

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NARROW

Phase II Multi-institutional Clinical Trial Result of Concurrent Cetuximab and Nivolumab in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma

Phase Ib Study of Chemoprevention with Green Tea Polyphenon E and Erlotinib in Patients with Advanced Premalignant Lesions (APL) of the Head and Neck

Editor's Note: The Pivotal Role of Integrin β1 in Metastasis of Head and Neck Squamous Cell Carcinoma

Honokiol Radiosensitizes Squamous Cell Carcinoma of the Head and Neck by Downregulation of Survivin

HER3 Targeting Sensitizes HNSCC to Cetuximab by Reducing HER3 Activity and HER2/HER3 Dimerization: Evidence from Cell Line and Patient-Derived Xenograft Models

CCR 20^th Anniversary Commentary: Prospects and Challenges of Therapeutic Nanoparticles in Cancer

Phase II Study of Cetuximab in Combination with Cisplatin and Radiation in Unresectable, Locally Advanced Head and Neck Squamous Cell Carcinoma: Eastern Cooperative Oncology Group Trial E3303

RRM2 Regulates Bcl-2 in Head and Neck and Lung Cancers: A Potential Target for Cancer Therapy

Chemoprevention of Head and Neck Cancer by Simultaneous Blocking of Epidermal Growth Factor Receptor and Cyclooxygenase-2 Signaling Pathways: Preclinical and Clinical Studies

The Pivotal Role of Integrin β1 in Metastasis of Head and Neck Squamous Cell Carcinoma

Therapeutic Nanoparticles for Drug Delivery in Cancer

Phase I Clinical and Pharmacodynamic Evaluation of Oral CI-1033 in Patients with Refractory Cancer

Enhancement of Docetaxel-Induced Cytotoxicity by Blocking Epidermal Growth Factor Receptor and Cyclooxygenase-2 Pathways in Squamous Cell Carcinoma of the Head and Neck

Progress in Chemoprevention Drug Development: The Promise of Molecular Biomarkers for Prevention of Intraepithelial Neoplasia and Cancer—A Plan to Move Forward

Fenretinide Activity in Retinoid-Resistant Oral Leukoplakia

Tumor Growth Inhibition by Simultaneously Blocking Epidermal Growth Factor Receptor and Cyclooxygenase-2 in a Xenograft Model

Phase 1 Clinical and Pharmacokinetics Evaluation of Oral CI-1033 in Patients with Refractory Cancer

Correlation of Protease-Activated Receptor-1 With Differentiation Markers in Squamous Cell Carcinoma of the Head and Neck and Its Implication in Lymph Node Metastasis

Simultaneously Targeting Epidermal Growth Factor Receptor Tyrosine Kinase and Cyclooxygenase-2, an Efficient Approach to Inhibition of Squamous Cell Carcinoma of the Head and Neck

Phase I Study of the Farnesyltransferase Inhibitor Lonafarnib with Paclitaxel in Solid Tumors

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