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Diana Mandelker
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Journal Articles

Germline DNA Damage Repair Variants and Prognosis of Patients with High-Risk or Metastatic Prostate Cancer

Konrad H. Stopsack, Joseph Vijai, Michael Conry, Jacob E. Berchuck, Yelena Kemel, Samantha E. Vasselman, Dory A. Freeman, Gwo-Shu M. Lee, Diana Mandelker, David B. Solit, Michael J. Morris, Kathryn L. Penney, Wassim Abida, Kenneth Offit, Lorelei A. Mucci, Philip W. Kantoff, Mark M. Pomerantz
Journal: Clinical Cancer Research
Clin Cancer Res (2025) 31 (1): 122–129.
https://doi.org/10.1158/1078-0432.CCR-24-2483
Published: 06 January 2025
View article titled, Germline DNA Damage Repair Variants and Prognosis of Patients with High-Risk or Metastatic Prostate Cancer
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Includes: Supplementary data
Journal Articles

Genotype-Directed Synthetic Cytotoxicity of ATR Inhibition with Radiotherapy

Victor Ng, Sonali Sinha, Ardijana Novaj, Jennifer Ma, Niamh McDermott, Xin Pei, Ana Leda F. Longhini, Helen Grimsley, Rui Gardner, Ezra Rosen, Simon N. Powell, Fresia Pareja, Diana Mandelker, Atif Khan, Jeremy Setton, Anne Roulston, Stephen Morris, Maria Koehler, Nancy Lee, Jorge Reis-Filho, Nadeem Riaz
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (24): 5643–5656.
https://doi.org/10.1158/1078-0432.CCR-24-0154
Published: 16 December 2024
View article titled, Genotype-Directed Synthetic Cytotoxicity of ATR Inhibition with Radiotherapy
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Includes: Supplementary data
Journal Articles

The Impact of Li‐Fraumeni and Germline Retinoblastoma Mutations on Leiomyosarcoma Initiation, Outcomes, and Genetic Testing Recommendations

Josephine K. Dermawan, David H. Abramson, Sarah Chiang, Martee L. Hensley, William D. Tap, Sujana Movva, Robert G. Maki, Diana Mandelker, Cristina R. Antonescu
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (20): 4780–4790.
https://doi.org/10.1158/1078-0432.CCR-24-1160
Published: 15 October 2024
View article titled, The Impact of Li‐Fraumeni and Germline Retinoblastoma Mutations on Leiomyosarcoma Initiation, Outcomes, and Genetic Testing Recommendations
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Includes: Supplementary data
Journal Articles

The Impact of Germline Alterations in Appendiceal Adenocarcinoma

Michael B. Foote, Henry Walch, Yelena Kemel, Efsevia Vakiani, Paul Johannet, Margaret Sheehan, Walid Chatila, Sebastian Chung, Garrett M. Nash, Anna Maio, Jinru Shia, Diana Mandelker, Michael Berger, Nikolaus Schultz, Luis A. Diaz, Andrea Cercek, Zsofia K. Stadler
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (14): 2631–2637.
https://doi.org/10.1158/1078-0432.CCR-22-3956
Published: 14 July 2023
View article titled, The Impact of Germline Alterations in Appendiceal Adenocarcinoma
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Includes: Supplementary data
Journal Articles

MAPK Pathway Genetic Alterations Are Associated with Prolonged Overall Survival in Low-Grade Serous Ovarian Carcinoma

Beryl Manning-Geist, Sushmita Gordhandas, Ying L. Liu, Qin Zhou, Alexia Iasonos, Arnaud Da Cruz Paula, Diana Mandelker, Kara Long Roche, Oliver Zivanovic, Anna Maio, Yelena Kemel, Dennis S. Chi, Roisin E. O'Cearbhaill, Carol Aghajanian, Britta Weigelt, M. Herman Chui, Rachel N. Grisham
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (20): 4456–4465.
https://doi.org/10.1158/1078-0432.CCR-21-4183
Published: 14 October 2022
View article titled, MAPK Pathway Genetic Alterations Are Associated with Prolonged Overall Survival in Low-Grade Serous Ovarian Carcinoma
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Includes: Supplementary data
Journal Articles

Inherited Germline Cancer Susceptibility Gene Variants in Individuals with Non–Muscle-Invasive Bladder Cancer

Eugene J. Pietzak, Karissa Whiting, Preethi Srinivasan, Chaitanya Bandlamudi, Aliya Khurram, Vijai Joseph, Aleksandra Walasek, Emily Bochner, Timothy Clinton, Nima Almassi, Hong Truong, Manuel R. de Jesus Escano, Michal Wiseman, Diana Mandelker, Yelena Kemel, Liying Zhang, Michael F. Walsh, Karen A. Cadoo, Jonathan A. Coleman, Hikmat Al-Ahmadie, Jonathan E. Rosenberg, Gopakumar V. Iyer, David B. Solit, Irina Ostrovnaya, Kenneth Offit, Mark E. Robson, Zsofia K. Stadler, Michael F. Berger, Dean F. Bajorin, Maria Carlo, Bernard H. Bochner
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (19): 4267–4277.
https://doi.org/10.1158/1078-0432.CCR-22-1006
Published: 03 October 2022
View article titled, Inherited Germline Cancer Susceptibility Gene Variants in Individuals with Non–Muscle-Invasive Bladder Cancer
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Includes: Supplementary data
Journal Articles

Morphologic and Genomic Characteristics of Breast Cancers Occurring in Individuals with Lynch Syndrome

Christopher J. Schwartz, Edaise M. da Silva, Antonio Marra, Andrea M. Gazzo, Pier Selenica, Vikas K. Rai, Diana Mandelker, Fresia Pareja, Maksym Misyura, Timothy M. D'Alfonso, Edi Brogi, Pamela Drullinsky, Pedram Razavi, Mark E. Robson, Joshua Z. Drago, Hannah Y. Wen, Liying Zhang, Britta Weigelt, Jinru Shia, Jorge S. Reis-Filho, Hong Zhang
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (2): 404–413.
https://doi.org/10.1158/1078-0432.CCR-21-2027
Published: 19 January 2022
View article titled, Morphologic and Genomic Characteristics of Breast Cancers Occurring in Individuals with Lynch Syndrome
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Includes: Supplementary data
Journal Articles

Characterization and Clinical Outcomes of DNA Mismatch Repair–deficient Small Bowel Adenocarcinoma

Alicia Latham, Jinru Shia, Zalak Patel, Diane L. Reidy-Lagunes, Neil H. Segal, Rona Yaeger, Karuna Ganesh, Louise Connell, Nancy E. Kemeny, David P. Kelsen, Jaclyn F. Hechtman, Garrett M. Nash, Philip B. Paty, Ahmet Zehir, Kaitlin A. Tkachuk, Rania Sheikh, Arnold J. Markowitz, Diana Mandelker, Kenneth Offit, Michael F. Berger, Andrea Cercek, Julio Garcia-Aguilar, Leonard B. Saltz, Martin R. Weiser, Zsofia K. Stadler
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (5): 1429–1437.
https://doi.org/10.1158/1078-0432.CCR-20-2892
Published: 01 March 2021
View article titled, Characterization and Clinical Outcomes of DNA Mismatch Repair–deficient Small Bowel Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Genomic Correlates of Disease Progression and Treatment Response in Prospectively Characterized Gliomas

Philip Jonsson, Andrew L. Lin, Robert J. Young, Natalie M. DiStefano, David M. Hyman, Bob T. Li, Michael F. Berger, Ahmet Zehir, Marc Ladanyi, David B. Solit, Angela G. Arnold, Zsofia K. Stadler, Diana Mandelker, Michael E. Goldberg, Juliann Chmielecki, Maryam Pourmaleki, Shahiba Q. Ogilvie, Shweta S. Chavan, Andrew T. McKeown, Malbora Manne, Allison Hyde, Kathryn Beal, T. Jonathan Yang, Craig P. Nolan, Elena Pentsova, Antonio Omuro, Igor T. Gavrilovic, Thomas J. Kaley, Eli L. Diamond, Jacqueline B. Stone, Christian Grommes, Adrienne Boire, Mariza Daras, Anna F. Piotrowski, Alexandra M. Miller, Philip H. Gutin, Timothy A. Chan, Viviane S. Tabar, Cameron W. Brennan, Marc Rosenblum, Lisa M. DeAngelis, Ingo K. Mellinghoff, Barry S. Taylor
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (18): 5537–5547.
https://doi.org/10.1158/1078-0432.CCR-19-0032
Published: 13 September 2019
View article titled, Genomic Correlates of Disease Progression and Treatment Response in Prospectively Characterized Gliomas
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Includes: Supplementary data
Journal Articles

Evaluating Mismatch Repair Deficiency in Pancreatic Adenocarcinoma: Challenges and Recommendations

Zishuo I. Hu, Jinru Shia, Zsofia K. Stadler, Anna M. Varghese, Marinela Capanu, Erin Salo-Mullen, Maeve A. Lowery, Luis A. Diaz, Jr, Diana Mandelker, Kenneth H. Yu, Alice Zervoudakis, David P. Kelsen, Christine A. Iacobuzio-Donahue, David S. Klimstra, Leonard B. Saltz, Ibrahim H. Sahin, Eileen M. O'Reilly
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (6): 1326–1336.
https://doi.org/10.1158/1078-0432.CCR-17-3099
Published: 14 March 2018
View article titled, Evaluating Mismatch Repair Deficiency in Pancreatic Adenocarcinoma: Challenges and Recommendations
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Journal Articles

Toward Concurrent Testing for Somatic and Germline Variants in Cancer Patients

Diana Mandelker
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16): 3987–3988.
https://doi.org/10.1158/1078-0432.CCR-16-1043
Published: 14 August 2016
View article titled, Toward Concurrent Testing for Somatic and Germline Variants in Cancer Patients
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