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Deborah A. Tweddle
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Journal Articles

Combination Therapies Targeting ALK-aberrant Neuroblastoma in Preclinical Models

Elizabeth R. Tucker, Irene Jiménez, Lindi Chen, Angela Bellini, Chiara Gorrini, Elizabeth Calton, Qiong Gao, Harvey Che, Evon Poon, Yann Jamin, Barbara Martins Da Costa, Karen Barker, Sumana Shrestha, J. Ciaran Hutchinson, Simran Dhariwal, Angharad Goodman, Elaine Del Nery, Pierre Gestraud, Jaydutt Bhalshankar, Yasmine Iddir, Elnaz Saberi-Ansari, Alexandra Saint-Charles, Birgit Geoerger, Maria Eugénia Marques Da Costa, Cécile Pierre-Eugène, Isabelle Janoueix-Lerosey, Didier Decaudin, Fariba Nemati, Angel M. Carcaboso, Didier Surdez, Olivier Delattre, Sally L. George, Louis Chesler, Deborah A. Tweddle, Gudrun Schleiermacher
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (7): 1317–1331.
https://doi.org/10.1158/1078-0432.CCR-22-2274
Published: 03 April 2023
View articletitled, Combination Therapies Targeting ALK-aberrant Neuroblastoma in Preclinical Models
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Includes: Supplementary data
Journal Articles

Detection of Circulating and Disseminated Neuroblastoma Cells Using the ImageStream Flow Cytometer for Use as Predictive and Pharmacodynamic Biomarkers

Swathi Merugu, Lindi Chen, Elizabeth Gavens, Hany Gabra, Mark Brougham, Guy Makin, Antony Ng, Dermot Murphy, Alem S. Gabriel, Michael L. Robinson, Jennifer H. Wright, Susan A. Burchill, Angharad Humphreys, Nick Bown, David Jamieson, Deborah A. Tweddle
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (1): 122–134.
https://doi.org/10.1158/1078-0432.CCR-19-0656
Published: 03 January 2020
View articletitled, Detection of Circulating and Disseminated Neuroblastoma Cells Using the ImageStream Flow Cytometer for Use as Predictive and Pharmacodynamic Biomarkers
Open the PDF for Detection of Circulating and Disseminated Neuroblastoma Cells Using the ImageStream Flow Cytometer for Use as Predictive and Pharmacodynamic Biomarkers in another window
Includes: Supplementary data
Journal Articles

A Multilocus Technique for Risk Evaluation of Patients with Neuroblastoma

Inge M. Ambros, Bettina Brunner, Gerhard Aigner, Clare Bedwell, Klaus Beiske, Jean Bénard, Nick Bown, Valerie Combaret, Jerome Couturier, Raffaella Defferrari, Nicole Gross, Marta Jeison, John Lunec, Barbara Marques, Tommy Martinsson, Katia Mazzocco, Rosa Noguera, Gudrun Schleiermacher, Frank Speleman, Ray Stallings, Gian Paolo Tonini, Deborah A. Tweddle, Alexander Valent, Ales Vicha, Nadine Van Roy, Eva Villamon, Andrea Ziegler, Sandra Preuner, Mario Drobics, Ruth Ladenstein, Gabriele Amann, Robert J.L. Schuit, Ulrike Pötschger, Peter F. Ambros
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (4): 792–804.
https://doi.org/10.1158/1078-0432.CCR-10-0830
Published: 15 February 2011
View articletitled, A Multilocus Technique for Risk Evaluation of Patients with Neuroblastoma
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Journal Articles

High Frequency of p53/MDM2/p14ARF Pathway Abnormalities in Relapsed Neuroblastoma

Jane Carr-Wilkinson, Kieran O'Toole, Katrina M. Wood, Christine C. Challen, Angela G. Baker, Julian R. Board, Laura Evans, Michael Cole, Nai-Kong V. Cheung, Joachim Boos, Gabriele Köhler, Ivo Leuschner, Andrew D.J. Pearson, John Lunec, Deborah A. Tweddle
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (4): 1108–1118.
https://doi.org/10.1158/1078-0432.CCR-09-1865
Published: 15 February 2010
View articletitled, High Frequency of p53/MDM2/p14ARF Pathway Abnormalities in Relapsed Neuroblastoma
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Journal Articles

Inhibition of Poly(ADP-Ribose) Polymerase-1 Enhances Temozolomide and Topotecan Activity against Childhood Neuroblastoma

Rachel A. Daniel, Agata L. Rozanska, Huw D. Thomas, Evan A. Mulligan, Yvette Drew, Deborah J. Castelbuono, Zdenek Hostomsky, E. Ruth Plummer, Alan V. Boddy, Deborah A. Tweddle, Nicola J. Curtin, Steven C. Clifford
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (4): 1241–1249.
https://doi.org/10.1158/1078-0432.CCR-08-1095
Published: 19 February 2009
View articletitled, Inhibition of Poly(ADP-Ribose) Polymerase-1 Enhances Temozolomide and Topotecan Activity against Childhood Neuroblastoma
Open the PDF for Inhibition of Poly(ADP-Ribose) Polymerase-1 Enhances Temozolomide and Topotecan Activity against Childhood Neuroblastoma in another window
Includes: Supplementary data
Journal Articles

Development of a Real-Time Polymerase Chain Reaction Assay for Prediction of the Uptake of Meta-[131I]iodobenzylguanidine by Neuroblastoma Tumors

Sean Carlin, Rob J. Mairs, Anthony G. McCluskey, Deborah A. Tweddle, Alan Sprigg, Christine Estlin, Julian Board, Rani E. George, Caroline Ellershaw, Andrew D. J. Pearson, John Lunec, Paolo G. Montaldo, Mirco Ponzoni, Berthe L. van Eck-Smit, Cees A. Hoefnagel, Marieke D. van den Brug, Godelieve A. M. Tytgat, Huib N. Caron
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (9): 3338–3344.
Published: 05 September 2003
View articletitled, Development of a Real-Time Polymerase Chain Reaction Assay for Prediction of the Uptake of Meta-[131I]iodobenzylguanidine by Neuroblastoma Tumors
Open the PDF for Development of a Real-Time Polymerase Chain Reaction Assay for Prediction of the Uptake of Meta-[131I]iodobenzylguanidine by Neuroblastoma Tumors in another window