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David Gentien
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Journal Articles

Non-invasive multi-cancer detection using DNA hypomethylation of LINE-1 retrotransposons

Marc Michel, Maryam Heidary, Anissa Mechri, Kévin Da Silva, Marine Gorse, Victoria Dixon, Klaus von Grafenstein, Charline Bianchi, Caroline Hego, Aurore Rampanou, Constance Lamy, Maud Kamal, Christophe Le Tourneau, Mathieu Séné, Ivan Bieche, Cécile Reyes, David Gentien, Marc-Henri Stern, Olivier Lantz, Luc Cabel, Jean-Yves Pierga, Francois-Clement Bidard, Chloé-Agathe Azencott, Charlotte Proudhon
Journal: Clinical Cancer Research
Clin Cancer Res (2024)
https://doi.org/10.1158/1078-0432.CCR-24-2669
Published: 02 December 2024
View article titled, Non-invasive multi-cancer detection using DNA hypomethylation of LINE-1 retrotransposons
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Includes: Supplementary data
Journal Articles

Immune Profiling of Combined Hepatocellular- Cholangiocarcinoma Reveals Distinct Subtypes and Activation of Gene Signatures Predictive of Response to Immunotherapy

Cong Trung Nguyen, Stefano Caruso, Pascale Maille, Aurélie Beaufrère, Jérémy Augustin, Loetitia Favre, Anaïs Pujals, Camille Boulagnon-Rombi, Rami Rhaiem, Giuliana Amaddeo, Luca di Tommaso, Alain Luciani, Hélène Regnault, Raffaele Brustia, Olivier Scatton, Frédéric Charlotte, Isabelle Brochériou, Daniele Sommacale, Patrick Soussan, Vincent Leroy, Alexis Laurent, Van Ky Le, Van To Ta, Hong Son Trinh, Thi Lan Tran, David Gentien, Audrey Rapinat, Jean Charles Nault, Manon Allaire, Sebastien Mulé, Jessica Zucman-Rossi, Jean-Michel Pawlotsky, Christophe Tournigand, Fouad Lafdil, Valérie Paradis, Julien Calderaro
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (3): 540–551.
https://doi.org/10.1158/1078-0432.CCR-21-1219
Published: 01 February 2022
View article titled, Immune Profiling of Combined Hepatocellular- Cholangiocarcinoma Reveals Distinct Subtypes and Activation of Gene Signatures Predictive of Response to Immunotherapy
Open the PDF for Immune Profiling of Combined Hepatocellular- Cholangiocarcinoma Reveals Distinct Subtypes and Activation of Gene Signatures Predictive of Response to Immunotherapy in another window
Includes: Supplementary data
Journal Articles

Intratumor CMS Heterogeneity Impacts Patient Prognosis in Localized Colon Cancer

Laetitia Marisa, Yuna Blum, Julien Taieb, Mira Ayadi, Camilla Pilati, Karine Le Malicot, Côme Lepage, Ramon Salazar, Daniela Aust, Alex Duval, Hélène Blons, Valérie Taly, David Gentien, Audrey Rapinat, Janick Selves, Sophie Mouillet-Richard, Valérie Boige, Jean-François Emile, Aurélien de Reyniès, Pierre Laurent-Puig
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (17): 4768–4780.
https://doi.org/10.1158/1078-0432.CCR-21-0529
Published: 01 September 2021
View article titled, Intratumor CMS Heterogeneity Impacts Patient Prognosis in Localized Colon Cancer
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Includes: Supplementary data
Journal Articles

Capecitabine Efficacy Is Correlated with TYMP and RB1 Expression in PDX Established from Triple-Negative Breast Cancers

Elisabetta Marangoni, Cécile Laurent, Florence Coussy, Rania El-Botty, Sophie Château-Joubert, Jean-Luc Servely, Ludmilla de Plater, Franck Assayag, Ahmed Dahmani, Elodie Montaudon, Fariba Nemati, Justine Fleury, Sophie Vacher, David Gentien, Audrey Rapinat, Pierre Foidart, Nor Eddine Sounni, Agnès Noel, Anne Vincent-Salomon, Marick Lae, Didier Decaudin, Sergio Roman-Roman, Ivan Bièche, Martine Piccart, Fabien Reyal
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (11): 2605–2615.
https://doi.org/10.1158/1078-0432.CCR-17-3490
Published: 31 May 2018
View article titled, Capecitabine Efficacy Is Correlated with TYMP and RB1 Expression in PDX Established from Triple-Negative Breast Cancers
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Includes: Supplementary data
Journal Articles

Genomic Copy Number Profiling Using Circulating Free Tumor DNA Highlights Heterogeneity in Neuroblastoma

Mathieu Chicard, Sandrine Boyault, Leo Colmet Daage, Wilfrid Richer, David Gentien, Gaelle Pierron, Eve Lapouble, Angela Bellini, Nathalie Clement, Isabelle Iacono, Stéphanie Bréjon, Marjorie Carrere, Cécile Reyes, Toby Hocking, Virginie Bernard, Michel Peuchmaur, Nadège Corradini, Cécile Faure-Conter, Carole Coze, Dominique Plantaz, Anne Sophie Defachelles, Estelle Thebaud, Marion Gambart, Frédéric Millot, Dominique Valteau-Couanet, Jean Michon, Alain Puisieux, Olivier Delattre, Valérie Combaret, Gudrun Schleiermacher
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2016) 22 (22): 5564–5573.
https://doi.org/10.1158/1078-0432.CCR-16-0500
Published: 14 November 2016
View article titled, Genomic Copy Number Profiling Using Circulating Free Tumor DNA Highlights Heterogeneity in Neuroblastoma
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Includes: Supplementary data
Journal Articles

Acquired Resistance to Endocrine Treatments Is Associated with Tumor-Specific Molecular Changes in Patient-Derived Luminal Breast Cancer Xenografts

Paul Cottu, Ivan Bièche, Franck Assayag, Rania El Botty, Sophie Chateau-Joubert, Aurélie Thuleau, Thomas Bagarre, Benoit Albaud, Audrey Rapinat, David Gentien, Pierre de la Grange, Vonick Sibut, Sophie Vacher, Rana Hatem, Jean-Luc Servely, Jean-Jacques Fontaine, Didier Decaudin, Jean-Yves Pierga, Sergio Roman-Roman, Elisabetta Marangoni
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (16): 4314–4325.
https://doi.org/10.1158/1078-0432.CCR-13-3230
Published: 13 August 2014
View article titled, Acquired Resistance to Endocrine Treatments Is Associated with Tumor-Specific Molecular Changes in Patient-Derived Luminal Breast Cancer Xenografts
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Includes: Supplementary data
Journal Articles

Pyrophosphorolysis-Activated Polymerization Detects Circulating Tumor DNA in Metastatic Uveal Melanoma

Jordan Madic, Sophie Piperno-Neumann, Vincent Servois, Aurore Rampanou, Maud Milder, Bénédicte Trouiller, David Gentien, Stéphanie Saada, Franck Assayag, Aurélie Thuleau, Fariba Nemati, Didier Decaudin, François-Clément Bidard, Laurence Desjardins, Pascale Mariani, Olivier Lantz, Marc-Henri Stern
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (14): 3934–3941.
https://doi.org/10.1158/1078-0432.CCR-12-0309
Published: 15 July 2012
View article titled, Pyrophosphorolysis-Activated Polymerization Detects Circulating Tumor DNA in Metastatic Uveal Melanoma
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Includes: Supplementary data
Journal Articles

Establishment and Characterization of a Panel of Human Uveal Melanoma Xenografts Derived from Primary and/or Metastatic Tumors

Fariba Némati, Xavier Sastre-Garau, Cécile Laurent, Jérôme Couturier, Pascale Mariani, Laurence Desjardins, Sophie Piperno-Neumann, Olivier Lantz, Bernard Asselain, Corine Plancher, Delphine Robert, Isabelle Péguillet, Marie-Hélène Donnadieu, Ahmed Dahmani, Marie-Andrée Bessard, David Gentien, Cécile Reyes, Simon Saule, Emmanuel Barillot, Sergio Roman-Roman, Didier Decaudin
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (8): 2352–2362.
https://doi.org/10.1158/1078-0432.CCR-09-3066
Published: 14 April 2010
View article titled, Establishment and Characterization of a Panel of Human Uveal Melanoma Xenografts Derived from Primary and/or Metastatic Tumors
Open the PDF for Establishment and Characterization of a Panel of Human Uveal Melanoma Xenografts Derived from Primary and/or Metastatic Tumors in another window
Includes: Supplementary data