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David G. Molleví
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Journal Articles

Noncanonical TGFβ Pathway Relieves the Blockade of IL1β/TGFβ-Mediated Crosstalk between Tumor and Stroma: TGFBR1 and TAK1 Inhibition in Colorectal Cancer

Natalia Guillén Díaz-Maroto, Rebeca Sanz-Pamplona, Mireia Berdiel-Acer, Francisco J. Cimas, Elena García, Samuel Gonçalves-Ribeiro, Nerea Albert, Gemma Garcia-Vicién, Gabriel Capella, Victor Moreno, Ramon Salazar, Alberto Villanueva, David G. Molleví
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (14): 4466–4479.
https://doi.org/10.1158/1078-0432.CCR-18-3957
Published: 15 July 2019
View article titled, Noncanonical TGFβ Pathway Relieves the Blockade of IL1β/TGFβ-Mediated Crosstalk between Tumor and Stroma: TGFBR1 and TAK1 Inhibition in Colorectal Cancer
Open the PDF for Noncanonical TGFβ Pathway Relieves the Blockade of IL1β/TGFβ-Mediated Crosstalk between Tumor and Stroma: TGFBR1 and TAK1 Inhibition in Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Orthoxenografts of Testicular Germ Cell Tumors Demonstrate Genomic Changes Associated with Cisplatin Resistance and Identify PDMP as a Resensitizing Agent

Josep M. Piulats, August Vidal, Francisco J. García-Rodríguez, Clara Muñoz, Marga Nadal, Catia Moutinho, María Martínez-Iniesta, Josefina Mora, Agnés Figueras, Elisabet Guinó, Laura Padullés, Àlvaro Aytés, David G. Molleví, Sara Puertas, Carmen Martínez-Fernández, Wilmar Castillo, Merce Juliachs, Victor Moreno, Purificación Muñoz, Milica Stefanovic, Miguel A. Pujana, Enric Condom, Manel Esteller, Josep R. Germà, Gabriel Capella, Lourdes Farré, Albert Morales, Francesc Viñals, Xavier García-del-Muro, Julián Cerón, Alberto Villanueva
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (15): 3755–3766.
https://doi.org/10.1158/1078-0432.CCR-17-1898
Published: 31 July 2018
View article titled, Orthoxenografts of Testicular Germ Cell Tumors Demonstrate Genomic Changes Associated with Cisplatin Resistance and Identify PDMP as a Resensitizing Agent
Open the PDF for Orthoxenografts of Testicular Germ Cell Tumors Demonstrate Genomic Changes Associated with Cisplatin Resistance and Identify PDMP as a Resensitizing Agent in another window
Includes: Supplementary data
Journal Articles

Lurbinectedin (PM01183), a New DNA Minor Groove Binder, Inhibits Growth of Orthotopic Primary Graft of Cisplatin-Resistant Epithelial Ovarian Cancer

August Vidal, Clara Muñoz, María-José Guillén, Jemina Moretó, Sara Puertas, María Martínez-Iniesta, Agnés Figueras, Laura Padullés, Francisco J. García-Rodriguez, Mireia Berdiel-Acer, Miguel A. Pujana, Ramón Salazar, Marta Gil-Martin, Lola Martí, Jordi Ponce, David G. Molleví, Gabriel Capella, Enric Condom, Francesc Viñals, Dori Huertas, Carmen Cuevas, Manel Esteller, Pablo Avilés, Alberto Villanueva
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (19): 5399–5411.
https://doi.org/10.1158/1078-0432.CCR-12-1513
Published: 30 September 2012
View article titled, Lurbinectedin (PM01183), a New DNA Minor Groove Binder, Inhibits Growth of Orthotopic Primary Graft of Cisplatin-Resistant Epithelial Ovarian Cancer
Open the PDF for Lurbinectedin (PM01183), a New DNA Minor Groove Binder, Inhibits Growth of Orthotopic Primary Graft of Cisplatin-Resistant Epithelial Ovarian Cancer in another window
Includes: Supplementary data