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David C. Smith
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Journal Articles

Development of 2 Bromodomain and Extraterminal Inhibitors With Distinct Pharmacokinetic and Pharmacodynamic Profiles for the Treatment of Advanced Malignancies

Gerald Falchook, Seth Rosen, Patricia LoRusso, Justin Watts, Shilpa Gupta, Catherine C. Coombs, Moshe Talpaz, Razelle Kurzrock, Monica Mita, Ryan Cassaday, Wael Harb, Julio Peguero, David C. Smith, Sarina A. Piha-Paul, Russ Szmulewitz, Marcus S. Noel, Swamy Yeleswaram, Phillip Liu, Julie Switzky, Gongfu Zhou, Fred Zheng, Amitkumar Mehta
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (6): 1247–1257.
https://doi.org/10.1158/1078-0432.CCR-18-4071
Published: 13 March 2020
View article titled, Development of 2 Bromodomain and Extraterminal Inhibitors With Distinct Pharmacokinetic and Pharmacodynamic Profiles for the Treatment of Advanced Malignancies
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Includes: Supplementary data
Journal Articles

A First-in-Human Phase I Study of the Anticancer Stem Cell Agent Ipafricept (OMP-54F28), a Decoy Receptor for Wnt Ligands, in Patients with Advanced Solid Tumors

Antonio Jimeno, Michael Gordon, Rashmi Chugh, Wells Messersmith, David Mendelson, Jakob Dupont, Robert Stagg, Ann M. Kapoun, Lu Xu, Shailaja Uttamsingh, Rainer K. Brachmann, David C. Smith
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (24): 7490–7497.
https://doi.org/10.1158/1078-0432.CCR-17-2157
Published: 14 December 2017
View article titled, A First-in-Human Phase I Study of the Anticancer Stem Cell Agent Ipafricept (OMP-54F28), a Decoy Receptor for Wnt Ligands, in Patients with Advanced Solid Tumors
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Journal Articles

A Phase I Dose Escalation and Expansion Study of the Anticancer Stem Cell Agent Demcizumab (Anti-DLL4) in Patients with Previously Treated Solid Tumors

David C. Smith, Peter D. Eisenberg, Georgy Manikhas, Rashmi Chugh, Matthew A. Gubens, Robert J. Stagg, Ann M. Kapoun, Lu Xu, Jakob Dupont, Branimir Sikic
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2014) 20 (24): 6295–6303.
https://doi.org/10.1158/1078-0432.CCR-14-1373
Published: 14 December 2014
View article titled, A Phase I Dose Escalation and Expansion Study of the Anticancer Stem Cell Agent Demcizumab (Anti-DLL4) in Patients with Previously Treated Solid Tumors
Open the PDF for A Phase I Dose Escalation and Expansion Study of the Anticancer Stem Cell Agent Demcizumab (Anti-DLL4) in Patients with Previously Treated Solid Tumors in another window
Includes: Supplementary data
Journal Articles

Characterization of Bone Metastases from Rapid Autopsies of Prostate Cancer Patients

Rohit Mehra, Chandan Kumar-Sinha, Sunita Shankar, Robert J. Lonigro, Xiaojun Jing, Neena E. Philips, Javed Siddiqui, Bo Han, Xuhong Cao, David C. Smith, Rajal B. Shah, Arul M. Chinnaiyan, Kenneth J. Pienta
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (12): 3924–3932.
https://doi.org/10.1158/1078-0432.CCR-10-3120
Published: 15 June 2011
View article titled, Characterization of Bone Metastases from Rapid Autopsies of Prostate Cancer Patients
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Includes: Supplementary data
Journal Articles

Determination of Intermediate Biomarker Expression Levels by Quantitative Reverse Transcription-Polymerase Chain Reaction in Oral Mucosa of Cancer Patients Treated with Liarozole

Qing Zeng, David C. Smith, Todd J. Suscovich, William E. Gooding, Donald L. Trump, Jennifer Rubin Grandis
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (6): 2245–2251.
Published: 01 June 2000
View article titled, Determination of Intermediate Biomarker Expression Levels by Quantitative Reverse Transcription-Polymerase Chain Reaction in Oral Mucosa of Cancer Patients Treated with Liarozole
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Journal Articles

Rapid (“Warm”) Autopsy Study for Procurement of Metastatic Prostate Cancer

Mark A. Rubin, Mathew Putzi, Neil Mucci, David C. Smith, Kirk Wojno, Susan Korenchuk, Kenneth J. Pienta
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (3): 1038–1045.
Published: 01 March 2000
View article titled, Rapid (“Warm”) Autopsy Study for Procurement of Metastatic Prostate Cancer
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Journal Articles

A Phase I Trial of Calcitriol (1,25-Dihydroxycholecalciferol) in Patients with Advanced Malignancy

David C. Smith, Candace S. Johnson, Catherine C. Freeman, Josephia Muindi, John W. Wilson, Donald L. Trump
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (6): 1339–1345.
Published: 01 June 1999
View article titled, A Phase I Trial of Calcitriol (1,25-Dihydroxycholecalciferol) in Patients with Advanced Malignancy
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