1-13 of 13
David A. Tuveson
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

AACR Cancer Centers Alliance: Fostering Collaboration and Innovation to Advance Lifesaving Scientific Discoveries for Patients

Carlos L. Arteaga, John L. Cleveland, Margaret Foti, Ruben A. Mesa, Louis M. Weiner, Cheryl L. Willman, David A. Tuveson
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (21): 4338–4340.
https://doi.org/10.1158/1078-0432.CCR-23-2625
Published: 01 November 2023
View article titled, AACR Cancer Centers Alliance: Fostering Collaboration and Innovation to Advance Lifesaving Scientific Discoveries for Patients
Open the PDF for AACR Cancer Centers Alliance: Fostering Collaboration and Innovation to Advance Lifesaving Scientific Discoveries for Patients in another window
Journal Articles

Precision Medicine in Pancreatic Cancer: Patient-Derived Organoid Pharmacotyping Is a Predictive Biomarker of Clinical Treatment Response

Toni T. Seppälä, Jacquelyn W. Zimmerman, Reecha Suri, Haley Zlomke, Gabriel D. Ivey, Annamaria Szabolcs, Christopher R. Shubert, John L. Cameron, William R. Burns, Kelly J. Lafaro, Jin He, Christopher L. Wolfgang, Ying S. Zou, Lei Zheng, David A. Tuveson, James R. Eshlemann, David P. Ryan, Alec C. Kimmelman, Theodore S. Hong, David T. Ting, Elizabeth M. Jaffee, Richard A. Burkhart
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (15): 3296–3307.
https://doi.org/10.1158/1078-0432.CCR-21-4165
Published: 02 August 2022
View article titled, Precision Medicine in Pancreatic Cancer: Patient-Derived Organoid Pharmacotyping Is a Predictive Biomarker of Clinical Treatment Response
Open the PDF for Precision Medicine in Pancreatic Cancer: Patient-Derived Organoid Pharmacotyping Is a Predictive Biomarker of Clinical Treatment Response in another window
Includes: Supplementary data
Journal Articles

Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer

Nina G. Steele, Giulia Biffi, Samantha B. Kemp, Yaqing Zhang, Donovan Drouillard, LiJyun Syu, Yuan Hao, Tobiloba E. Oni, Erin Brosnan, Ela Elyada, Abhishek Doshi, Christa Hansma, Carlos Espinoza, Ahmed Abbas, Stephanie The, Valerie Irizarry-Negron, Christopher J. Halbrook, Nicole E. Franks, Megan T. Hoffman, Kristee Brown, Eileen S. Carpenter, Zeribe C. Nwosu, Craig Johnson, Fatima Lima, Michelle A. Anderson, Youngkyu Park, Howard C. Crawford, Costas A. Lyssiotis, Timothy L. Frankel, Arvind Rao, Filip Bednar, Andrzej A. Dlugosz, Jonathan B. Preall, David A. Tuveson, Benjamin L. Allen, Marina Pasca di Magliano
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2021) 27 (7): 2023–2037.
https://doi.org/10.1158/1078-0432.CCR-20-3715
Published: 01 April 2021
View article titled, Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer
Open the PDF for Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Detection of Chemotherapy-resistant Pancreatic Cancer Using a Glycan Biomarker, sTRA

ChongFeng Gao, Luke Wisniewski, Ying Liu, Ben Staal, Ian Beddows, Dennis Plenker, Mohammed Aldakkak, Johnathan Hall, Daniel Barnett, Mirna Kheir Gouda, Peter Allen, Richard Drake, Amer Zureikat, Ying Huang, Douglas Evans, Aatur Singhi, Randall E. Brand, David A. Tuveson, Susan Tsai, Brian B. Haab
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (1): 226–236.
https://doi.org/10.1158/1078-0432.CCR-20-2475
Published: 04 January 2021
View article titled, Detection of Chemotherapy-resistant Pancreatic Cancer Using a Glycan Biomarker, sTRA
Open the PDF for Detection of Chemotherapy-resistant Pancreatic Cancer Using a Glycan Biomarker, sTRA in another window
Includes: Supplementary data
Journal Articles

Abstract S04-01: Famotidine use and quantitative symptom tracking for COVID-19 in nonhospitalized patients: A case series

Tobias Janowitz, Eva C. Gablenz, David J. Pattinson, Timothy C. Wang, Joseph Conigliaro, Kevin J. Tracey, David A. Tuveson
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (18_Supplement): S04-01.
https://doi.org/10.1158/1557-3265.COVID-19-S04-01
Published: 15 September 2020
View article titled, Abstract S04-01: Famotidine use and quantitative symptom tracking for COVID-19 in nonhospitalized patients: A case series
Journal Articles

Bioactivation of Napabucasin Triggers Reactive Oxygen Species–Mediated Cancer Cell Death

Fieke E.M. Froeling, Manojit Mosur Swamynathan, Astrid Deschênes, Iok In Christine Chio, Erin Brosnan, Melissa A. Yao, Priya Alagesan, Matthew Lucito, Juying Li, An-Yun Chang, Lloyd C. Trotman, Pascal Belleau, Youngkyu Park, Harry A. Rogoff, James D. Watson, David A. Tuveson
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (23): 7162–7174.
https://doi.org/10.1158/1078-0432.CCR-19-0302
Published: 02 December 2019
View article titled, Bioactivation of Napabucasin Triggers Reactive Oxygen Species–Mediated Cancer Cell Death
Open the PDF for Bioactivation of Napabucasin Triggers Reactive Oxygen Species–Mediated Cancer Cell Death in another window
Includes: Supplementary data
Journal Articles

Identification of Resistance Pathways Specific to Malignancy Using Organoid Models of Pancreatic Cancer

Mariano Ponz-Sarvise, Vincenzo Corbo, Hervé Tiriac, Dannielle D. Engle, Kristopher K. Frese, Tobiloba E. Oni, Chang-Il Hwang, Daniel Öhlund, Iok In Christine Chio, Lindsey A. Baker, Dea Filippini, Kevin Wright, Tashinga E. Bapiro, Pearl Huang, Paul Smith, Kenneth H. Yu, Duncan I. Jodrell, Youngkyu Park, David A. Tuveson
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (22): 6742–6755.
https://doi.org/10.1158/1078-0432.CCR-19-1398
Published: 15 November 2019
View article titled, Identification of Resistance Pathways Specific to Malignancy Using Organoid Models of Pancreatic Cancer
Open the PDF for Identification of Resistance Pathways Specific to Malignancy Using Organoid Models of Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract B16: Using human patient-derived organoids to identify genetic dependencies in pancreatic cancer

Lindsey A. Baker, Hervé Tiriac, Vincenzo Corbo, Sylvia F. Boj, Chang-il Hwang, Iok In Christine Chio, Danielle D. Engle, Myrthe Jager, Mariano Ponz-Sarvise, Mona S. Spector, Ana Gracanin, Tobiloba Oni, Kenneth H. Yu, Ruben van Boxtel, Meritxell Huch, Keith D. Rivera, John P. Wilson, Michael E. Feigin, Daniel Öhlund, Abram Handly-Santana, Christine M. Ardito-Abraham, Michael Ludwig, Ela Elyada, Brinda Alagesan, Giulia Biffi, Georgi N. Yordanov, Bethany Delcuze, Brianna Creighton, Kevin Wright, Youngkyu Park, Folkert H.M. Morsink, I. Quintus Molenaar, Inne H. Borel Rinkes, Edwin Cuppen, Yuan Hao, Ying Jin, Isaac J. Nijman, Christine Iacobuzio-Donahue, Steven D. Leach, Darryl J. Pappin, Molly Hammell, David S. Klimstra, Olca Basturk, Ralph H. Hruban, George Johan Offerhaus, Robert G.J. Vries, Hans Clevers, David A. Tuveson
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16_Supplement): B16.
https://doi.org/10.1158/1557-3265.PDX16-B16
Published: 15 August 2016
View article titled, Abstract B16: Using human patient-derived organoids to identify genetic dependencies in pancreatic cancer
Journal Articles

Decreased Serum Thrombospondin-1 Levels in Pancreatic Cancer Patients Up to 24 Months Prior to Clinical Diagnosis: Association with Diabetes Mellitus

Claire Jenkinson, Victoria L. Elliott, Anthony Evans, Lucy Oldfield, Rosalind E. Jenkins, Darragh P. O'Brien, Sophia Apostolidou, Aleksandra Gentry-Maharaj, Evangelia-O Fourkala, Ian J. Jacobs, Usha Menon, Trevor Cox, Fiona Campbell, Stephen P. Pereira, David A. Tuveson, B. Kevin Park, William Greenhalf, Robert Sutton, John F. Timms, John P. Neoptolemos, Eithne Costello
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2016) 22 (7): 1734–1743.
https://doi.org/10.1158/1078-0432.CCR-15-0879
Published: 31 March 2016
View article titled, Decreased Serum Thrombospondin-1 Levels in Pancreatic Cancer Patients Up to 24 Months Prior to Clinical Diagnosis: Association with Diabetes Mellitus
Open the PDF for Decreased Serum Thrombospondin-1 Levels in Pancreatic Cancer Patients Up to 24 Months Prior to Clinical Diagnosis: Association with Diabetes Mellitus in another window
Includes: Supplementary data
Journal Articles

Abstract IA5: Developing therapeutics in mice with ductal pancreatic cancer

David A. Tuveson
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (10_Supplement): IA5.
https://doi.org/10.1158/1078-0432.MECHRES-IA5
Published: 04 March 2013
View article titled, Abstract IA5: Developing therapeutics in mice with ductal pancreatic cancer
Open the PDF for Abstract IA5: Developing therapeutics in mice with ductal pancreatic cancer in another window
Journal Articles

The Pancreas Cancer Microenvironment

Christine Feig, Aarthi Gopinathan, Albrecht Neesse, Derek S. Chan, Natalie Cook, David A. Tuveson
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (16): 4266–4276.
https://doi.org/10.1158/1078-0432.CCR-11-3114
Published: 14 August 2012
View article titled, The Pancreas Cancer Microenvironment
Open the PDF for The Pancreas Cancer Microenvironment in another window
Journal Articles

A Phase I Trial of the Oral, Multikinase Inhibitor Sorafenib in Combination with Carboplatin and Paclitaxel

Keith T. Flaherty, Joan Schiller, Lynn M. Schuchter, Glenn Liu, David A. Tuveson, Maryann Redlinger, Chetan Lathia, Chenghua Xia, Oana Petrenciuc, Sunil R. Hingorani, Michael A. Jacobetz, Patricia A. Van Belle, David Elder, Marcia S. Brose, Barbara L. Weber, Mark R. Albertini, Peter J. O'Dwyer
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (15): 4836–4842.
https://doi.org/10.1158/1078-0432.CCR-07-4123
Published: 01 August 2008
View article titled, A Phase I Trial of the Oral, Multikinase Inhibitor Sorafenib in Combination with Carboplatin and Paclitaxel
Open the PDF for A Phase I Trial of the Oral, Multikinase Inhibitor Sorafenib in Combination with Carboplatin and Paclitaxel in another window
Journal Articles

The Use of Targeted Mouse Models for Preclinical Testing of Novel Cancer Therapeutics

Kenneth P. Olive, David A. Tuveson
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (18): 5277–5287.
https://doi.org/10.1158/1078-0432.CCR-06-0436
Published: 25 September 2006
View article titled, The Use of Targeted Mouse Models for Preclinical Testing of Novel Cancer Therapeutics
Open the PDF for The Use of Targeted Mouse Models for Preclinical Testing of Novel Cancer Therapeutics in another window