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Dara L. Aisner
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Journal Articles

Wake Up and Smell the Fusions: Single-Modality Molecular Testing Misses Drivers

Kurtis D. Davies, Dara L. Aisner
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (15): 4586–4588.
DOI: https://doi.org/10.1158/1078-0432.CCR-19-1361
Published: 01 August 2019
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Final Report of a Phase I Trial of Olaparib with Cetuximab and Radiation for Heavy Smoker Patients with Locally Advanced Head and Neck Cancer

Sana D. Karam, Krishna Reddy, Patrick J. Blatchford, Tim Waxweiler, Alicia M. DeLouize, Ayman Oweida, Hilary Somerset, Carrie Marshall, Christian Young, Kurtis D. Davies, Madeleine Kane, Aik Choo Tan, Xiao Jing Wang, Antonio Jimeno, Dara L. Aisner, Daniel W. Bowles, David Raben
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (20): 4949–4959.
DOI: https://doi.org/10.1158/1078-0432.CCR-18-0467
Published: 15 October 2018
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Includes: Supplementary data
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Resistance Mechanisms to Targeted Therapies in ROS1+ and ALK+ Non–small Cell Lung Cancer

Caroline E. McCoach, Anh T. Le, Katherine Gowan, Kenneth Jones, Laura Schubert, Andrea Doak, Adriana Estrada-Bernal, Kurtis D. Davies, Daniel T. Merrick, Paul A. Bunn, Jr, W. Tom Purcell, Rafal Dziadziuszko, Marileila Varella-Garcia, Dara L. Aisner, D. Ross Camidge, Robert C. Doebele
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (14): 3334–3347.
DOI: https://doi.org/10.1158/1078-0432.CCR-17-2452
Published: 15 July 2018
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Includes: Supplementary data
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Clinical Utility of Cell-Free DNA for the Detection of ALK Fusions and Genomic Mechanisms of ALK Inhibitor Resistance in Non–Small Cell Lung Cancer

Caroline E. McCoach, Collin M. Blakely, Kimberly C. Banks, Benjamin Levy, Ben M. Chue, Victoria M. Raymond, Anh T. Le, Christine E. Lee, Joseph Diaz, Saiama N. Waqar, William T. Purcell, Dara L. Aisner, Kurtis D. Davies, Richard B. Lanman, Alice T. Shaw, Robert C. Doebele
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (12): 2758–2770.
DOI: https://doi.org/10.1158/1078-0432.CCR-17-2588
Published: 14 June 2018
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Includes: Supplementary data
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The Impact of Smoking and TP53 Mutations in Lung Adenocarcinoma Patients with Targetable Mutations—The Lung Cancer Mutation Consortium (LCMC2)

Dara L. Aisner, Lynette M. Sholl, Lynne D. Berry, Michael R. Rossi, Heidi Chen, Junya Fujimoto, Andre L. Moreira, Suresh S. Ramalingam, Liza C. Villaruz, Gregory A. Otterson, Eric Haura, Katerina Politi, Bonnie Glisson, Jeremy Cetnar, Edward B. Garon, Joan Schiller, Saiama N. Waqar, Lecia V. Sequist, Julie Brahmer, Yu Shyr, Kelly Kugler, Ignacio I. Wistuba, Bruce E. Johnson, John D. Minna, Mark G. Kris, Paul A. Bunn, David J. Kwiatkowski
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (5): 1038–1047.
DOI: https://doi.org/10.1158/1078-0432.CCR-17-2289
Published: 28 February 2018
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Includes: Supplementary data
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Is There Clinical Value to Prognostic Signatures in Early-Stage NSCLC?

Paul A. Bunn, Jr, Fred R. Hirsch, Dara L. Aisner
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (7): 1727–1729.
DOI: https://doi.org/10.1158/1078-0432.CCR-13-3387
Published: 31 March 2014
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Phase I Study of Oral Rigosertib (ON 01910.Na), a Dual Inhibitor of the PI3K and Plk1 Pathways, in Adult Patients with Advanced Solid Malignancies

Daniel W. Bowles, Jennifer R. Diamond, Elaine T. Lam, Colin D. Weekes, David P. Astling, Ryan T. Anderson, Stephen Leong, Lia Gore, Marileila Varella-Garcia, Brian W. Vogler, Stephen B. Keysar, Elizabeth Freas, Dara L. Aisner, Chen Ren, Aik-Chook Tan, Francois Wilhelm, Manoj Maniar, S. Gail Eckhardt, Wells A. Messersmith, Antonio Jimeno
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (6): 1656–1665.
DOI: https://doi.org/10.1158/1078-0432.CCR-13-2506
Published: 13 March 2014
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Includes: Supplementary data
Journal Articles

Identifying and Targeting ROS1 Gene Fusions in Non–Small Cell Lung Cancer

Kurtis D. Davies, Anh T. Le, Mariana F. Theodoro, Margaret C. Skokan, Dara L. Aisner, Eamon M. Berge, Luigi M. Terracciano, Federico Cappuzzo, Matteo Incarbone, Massimo Roncalli, Marco Alloisio, Armando Santoro, D. Ross Camidge, Marileila Varella-Garcia, Robert C. Doebele
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (17): 4570–4579.
DOI: https://doi.org/10.1158/1078-0432.CCR-12-0550
Published: 30 August 2012
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Includes: Supplementary data
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Mechanisms of Resistance to Crizotinib in Patients with ALK Gene Rearranged Non–Small Cell Lung Cancer

Robert C. Doebele, Amanda B. Pilling, Dara L. Aisner, Tatiana G. Kutateladze, Anh T. Le, Andrew J. Weickhardt, Kimi L. Kondo, Derek J. Linderman, Lynn E. Heasley, Wilbur A. Franklin, Marileila Varella-Garcia, D. Ross Camidge
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (5): 1472–1482.
DOI: https://doi.org/10.1158/1078-0432.CCR-11-2906
Published: 01 March 2012
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Includes: Supplementary data