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Claudia Bertan
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Journal Articles

NXP800 activates the unfolded protein response, altering AR and E2F function to impact castration-resistant prostate cancer growth

Jonathan Welti, Denisa Bogdan, Ines Figueiredo, Ilsa Coleman, Juan Jiménez Vacas, Kate Liodaki, Franziska Weigl, Lorenzo Buroni, Wanting Zeng, Ilona Bernett, Claudia Bertan, Theodoros I. Roumeliotis, Amandeep Bhamra, Jan Rekowski, Bora Gurel, Antje J. Neeb, Jian Ning, Dapei Li, Veronica S. Gil, Ruth Riisnaes, Susana Miranda, Mateus Crespo, Ana Ferreira, Nina Tunariu, Elisa Pasqua, Nicola Chessum, Matthew Cheeseman, Robert te Poele, Marissa Powers, Suzanne Carreira, Jyoti Choudhary, Paul Clarke, Udai Banerji, Amanda Swain, Keith Jones, Wei Yuan, Paul Workman, Peter S. Nelson, Johann S. de Bono, Adam Sharp
Journal: Clinical Cancer Research
Clin Cancer Res (2025)
https://doi.org/10.1158/1078-0432.CCR-24-2386
Published: 09 January 2025
View article titled, NXP800 activates the unfolded protein response, altering AR and E2F function to impact castration-resistant prostate cancer growth
Open the PDF for NXP800 activates the unfolded protein response, altering AR and E2F function to impact castration-resistant prostate cancer growth in another window
Includes: Supplementary data
Journal Articles

Characterizing CDK12-Mutated Prostate Cancers

Pasquale Rescigno, Bora Gurel, Rita Pereira, Mateus Crespo, Jan Rekowski, Mattia Rediti, Maialen Barrero, Joaquin Mateo, Diletta Bianchini, Carlo Messina, Maria D. Fenor de la Maza, Khobe Chandran, Juliet Carmichael, Christina Guo, Alec Paschalis, Adam Sharp, George Seed, Ines Figueiredo, Maryou Lambros, Susana Miranda, Ana Ferreira, Claudia Bertan, Ruth Riisnaes, Nuria Porta, Wei Yuan, Suzanne Carreira, Johann S. de Bono
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2021) 27 (2): 566–574.
https://doi.org/10.1158/1078-0432.CCR-20-2371
Published: 19 January 2021
View article titled, Characterizing CDK12-Mutated Prostate Cancers
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Includes: Supplementary data
Journal Articles

Diverse AR Gene Rearrangements Mediate Resistance to Androgen Receptor Inhibitors in Metastatic Prostate Cancer

Yingming Li, Rendong Yang, Christine M. Henzler, Yeung Ho, Courtney Passow, Benjamin Auch, Suzanne Carreira, Daniel Nava Rodrigues, Claudia Bertan, Tae Hyun Hwang, David A. Quigley, Ha X. Dang, Colm Morrissey, Michael Fraser, Stephen R. Plymate, Christopher A. Maher, Felix Y. Feng, Johann S. de Bono, Scott M. Dehm
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (8): 1965–1976.
https://doi.org/10.1158/1078-0432.CCR-19-3023
Published: 15 April 2020
View article titled, Diverse <em>AR</em> Gene Rearrangements Mediate Resistance to Androgen Receptor Inhibitors in Metastatic Prostate Cancer
Open the PDF for Diverse <em>AR</em> Gene Rearrangements Mediate Resistance to Androgen Receptor Inhibitors in Metastatic Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

SPOP-Mutated/CHD1-Deleted Lethal Prostate Cancer and Abiraterone Sensitivity

Gunther Boysen, Daniel N. Rodrigues, Pasquale Rescigno, George Seed, David Dolling, Ruth Riisnaes, Mateus Crespo, Zafeiris Zafeiriou, Semini Sumanasuriya, Diletta Bianchini, Joanne Hunt, Deirdre Moloney, Raquel Perez-Lopez, Nina Tunariu, Susana Miranda, Inês Figueiredo, Ana Ferreira, Rossitza Christova, Veronica Gil, Sara Aziz, Claudia Bertan, Flavia M. de Oliveira, Mark Atkin, Matthew Clarke, Jane Goodall, Adam Sharp, Theresa MacDonald, Mark A. Rubin, Wei Yuan, Christopher E. Barbieri, Suzanne Carreira, Joaquin Mateo, Johann S. de Bono
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (22): 5585–5593.
https://doi.org/10.1158/1078-0432.CCR-18-0937
Published: 15 November 2018
View article titled, SPOP-Mutated/CHD1-Deleted Lethal Prostate Cancer and Abiraterone Sensitivity
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Includes: Supplementary data
Journal Articles

Single-Cell Analyses of Prostate Cancer Liquid Biopsies Acquired by Apheresis

Maryou B. Lambros, George Seed, Semini Sumanasuriya, Veronica Gil, Mateus Crespo, Mariane Fontes, Rob Chandler, Niven Mehra, Gemma Fowler, Berni Ebbs, Penny Flohr, Susana Miranda, Wei Yuan, Alan Mackay, Ana Ferreira, Rita Pereira, Claudia Bertan, Ines Figueiredo, Ruth Riisnaes, Daniel Nava Rodrigues, Adam Sharp, Jane Goodall, Gunther Boysen, Suzanne Carreira, Diletta Bianchini, Pasquale Rescigno, Zafeiris Zafeiriou, Joanne Hunt, Deirdre Moloney, Lucy Hamilton, Rui P. Neves, Joost Swennenhuis, Kiki Andree, Nikolas H. Stoecklein, Leon W.M.M. Terstappen, Johann S. de Bono
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (22): 5635–5644.
https://doi.org/10.1158/1078-0432.CCR-18-0862
Published: 15 November 2018
View article titled, Single-Cell Analyses of Prostate Cancer Liquid Biopsies Acquired by Apheresis
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Includes: Supplementary data
Journal Articles

Gene Copy Number Estimation from Targeted Next-Generation Sequencing of Prostate Cancer Biopsies: Analytic Validation and Clinical Qualification

George Seed, Wei Yuan, Joaquin Mateo, Suzanne Carreira, Claudia Bertan, Maryou Lambros, Gunther Boysen, Roberta Ferraldeschi, Susana Miranda, Ines Figueiredo, Ruth Riisnaes, Mateus Crespo, Daniel Nava Rodrigues, Eric Talevich, Dan R. Robinson, Lakshmi P. Kunju, Yi-Mi Wu, Robert Lonigro, Shahneen Sandhu, Arul M. Chinnaiyan, Johann S. de Bono
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (20): 6070–6077.
https://doi.org/10.1158/1078-0432.CCR-17-0972
Published: 12 October 2017
View article titled, Gene Copy Number Estimation from Targeted Next-Generation Sequencing of Prostate Cancer Biopsies: Analytic Validation and Clinical Qualification
Open the PDF for Gene Copy Number Estimation from Targeted Next-Generation Sequencing of Prostate Cancer Biopsies: Analytic Validation and Clinical Qualification in another window
Includes: Supplementary data