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Journal Articles

Initial Whole-Genome Sequencing of Plasma Cell Neoplasms in First Responders and Recovery Workers Exposed to the World Trade Center Attack of September 11, 2001

Clin Cancer Res (2021) 27 (7): 2111–2118.

DOI: https://doi.org/10.1158/1078-0432.CCR-20-2245

Published: 01 April 2021

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Includes: Supplementary data

Journal Articles

The Genetic Evolution of Treatment-Resistant Cutaneous, Acral, and Uveal Melanomas

Clin Cancer Res (2021) 27 (5): 1516–1525.

DOI: https://doi.org/10.1158/1078-0432.CCR-20-2984

Published: 01 March 2021

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Includes: Supplementary data

Journal Articles

Genomic Methods Identify Homologous Recombination Deficiency in Pancreas Adenocarcinoma and Optimize Treatment Selection

Clin Cancer Res (2020) 26 (13): 3239–3247.

DOI: https://doi.org/10.1158/1078-0432.CCR-20-0418

Published: 01 July 2020

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Includes: Supplementary data

Journal Articles

Evaluating Mismatch Repair Deficiency in Pancreatic Adenocarcinoma: Challenges and Recommendations

Zishuo I. Hu, Jinru Shia, Zsofia K. Stadler, Anna M. Varghese, Marinela Capanu, Erin Salo-Mullen, Maeve A. Lowery, Luis A. Diaz, Jr, Diana Mandelker, Kenneth H. Yu, Alice Zervoudakis, David P. Kelsen, Christine A. Iacobuzio-Donahue, David S. Klimstra, Leonard B. Saltz, Ibrahim H. Sahin, Eileen M. O'Reilly

Clin Cancer Res (2018) 24 (6): 1326–1336.

DOI: https://doi.org/10.1158/1078-0432.CCR-17-3099

Published: 14 March 2018

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Journal Articles

Real-Time Genomic Profiling of Pancreatic Ductal Adenocarcinoma: Potential Actionability and Correlation with Clinical Phenotype

Clin Cancer Res (2017) 23 (20): 6094–6100.

DOI: https://doi.org/10.1158/1078-0432.CCR-17-0899

Published: 12 October 2017

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Journal Articles

Transcriptional Mechanisms of Resistance to Anti–PD-1 Therapy

Clin Cancer Res (2017) 23 (12): 3168–3180.

DOI: https://doi.org/10.1158/1078-0432.CCR-17-0270

Published: 14 June 2017

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Includes: Supplementary data

Journal Articles

Mutant p53 Together with TGFβ Signaling Influence Organ-Specific Hematogenous Colonization Patterns of Pancreatic Cancer

Yi Zhong, Anne Macgregor-Das, Tyler Saunders, Martin C. Whittle, Alvin Makohon-Moore, Zachary A. Kohutek, Justin Poling, Brian T. Herbst, Breanna M. Javier, Leslie Cope, Steven D. Leach, Sunil R. Hingorani, Christine A. Iacobuzio-Donahue

Clin Cancer Res (2017) 23 (6): 1607–1620.

DOI: https://doi.org/10.1158/1078-0432.CCR-15-1615

Published: 14 March 2017

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Includes: Supplementary data

Journal Articles

Cyst Fluid Analysis in Pancreatic Intraductal Papillary Mucinous Neoplasms

Peter J. Allen, Christine A. Iacobuzio-Donahue, David S. Klimstra

Clin Cancer Res (2016) 22 (20): 4966–4967.

DOI: https://doi.org/10.1158/1078-0432.CCR-16-1462

Published: 13 October 2016

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Journal Articles

Functional p38 MAPK Identified by Biomarker Profiling of Pancreatic Cancer Restrains Growth through JNK Inhibition and Correlates with Improved Survival

Yi Zhong, Yoshiki Naito, Leslie Cope, Salvador Naranjo-Suarez, Tyler Saunders, Seung-Mo Hong, Michael G. Goggins, Joseph M. Herman, Christopher L. Wolfgang, Christine A. Iacobuzio-Donahue

Clin Cancer Res (2014) 20 (23): 6200–6211.

DOI: https://doi.org/10.1158/1078-0432.CCR-13-2823

Published: 30 November 2014

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Includes: Supplementary data

Journal Articles

Novel Methylation Biomarker Panel for the Early Detection of Pancreatic Cancer

Joo Mi Yi, Angela A. Guzzetta, Vasudev J. Bailey, Stephanie R. Downing, Leander Van Neste, Katherine B. Chiappinelli, Brian P. Keeley, Alejandro Stark, Alexander Herrera, Christopher Wolfgang, Emmanouil P. Pappou, Christine A. Iacobuzio-Donahue, Michael G. Goggins, James G. Herman, Tza-Huei Wang, Stephen B. Baylin, Nita Ahuja

Clin Cancer Res (2013) 19 (23): 6544–6555.

DOI: https://doi.org/10.1158/1078-0432.CCR-12-3224

Published: 01 December 2013

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Includes: Supplementary data

Journal Articles

Genetically Defined Subsets of Human Pancreatic Cancer Show Unique In Vitro Chemosensitivity

Yunfeng Cui, Jacqueline A. Brosnan, Amanda L. Blackford, Surojit Sur, Ralph H. Hruban, Kenneth W. Kinzler, Bert Vogelstein, Anirban Maitra, Luis A. Diaz, Jr, Christine A. Iacobuzio-Donahue, James R. Eshleman

Clin Cancer Res (2012) 18 (23): 6519–6530.

DOI: https://doi.org/10.1158/1078-0432.CCR-12-0827

Published: 29 November 2012

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Includes: Supplementary data

Journal Articles

Clinical Significance of the Genetic Landscape of Pancreatic Cancer and Implications for Identification of Potential Long-term Survivors

Shinichi Yachida, Catherine M. White, Yoshiki Naito, Yi Zhong, Jacqueline A. Brosnan, Anne M. Macgregor-Das, Richard A. Morgan, Tyler Saunders, Daniel A. Laheru, Joseph M. Herman, Ralph H. Hruban, Alison P. Klein, Siân Jones, Victor Velculescu, Christopher L. Wolfgang, Christine A. Iacobuzio-Donahue

Clin Cancer Res (2012) 18 (22): 6339–6347.

DOI: https://doi.org/10.1158/1078-0432.CCR-12-1215

Published: 14 November 2012

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Includes: Supplementary data

Journal Articles

CpG Island Methylator Phenotype–Positive Tumors in the Absence of MLH1 Methylation Constitute a Distinct Subset of Duodenal Adenocarcinomas and Are Associated with Poor Prognosis

Tao Fu, Emmanouil P. Pappou, Angela A. Guzzetta, Jana Jeschke, Ruby Kwak, Pujan Dave, Craig M. Hooker, Richard Morgan, Stephen B. Baylin, Christine A. Iacobuzio-Donahue, Christopher L. Wolfgang, Nita Ahuja

Clin Cancer Res (2012) 18 (17): 4743–4752.

DOI: https://doi.org/10.1158/1078-0432.CCR-12-0707

Published: 30 August 2012

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Includes: Supplementary data

Journal Articles

Genetic Basis of Pancreas Cancer Development and Progression: Insights from Whole-Exome and Whole-Genome Sequencing

Christine A. Iacobuzio-Donahue, Victor E. Velculescu, Christopher L. Wolfgang, Ralph H. Hruban

Clin Cancer Res (2012) 18 (16): 4257–4265.

DOI: https://doi.org/10.1158/1078-0432.CCR-12-0315

Published: 14 August 2012

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Journal Articles

Genomic and Epigenomic Integration Identifies a Prognostic Signature in Colon Cancer

Joo Mi Yi, Mashaal Dhir, Leander Van Neste, Stephanie R. Downing, Jana Jeschke, Sabine C. Glöckner, Marilia de Freitas Calmon, Craig M. Hooker, Juan M. Funes, Chris Boshoff, Kim M. Smits, Manon van Engeland, Matty P. Weijenberg, Christine A. Iacobuzio-Donahue, James G. Herman, Kornel E. Schuebel, Stephen B. Baylin, Nita Ahuja

Clin Cancer Res (2011) 17 (6): 1535–1545.

DOI: https://doi.org/10.1158/1078-0432.CCR-10-2509

Published: 15 March 2011

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Includes: Supplementary data

Journal Articles

SMAD4 Gene Mutations Are Associated with Poor Prognosis in Pancreatic Cancer

Clin Cancer Res (2009) 15 (14): 4674–4679.

DOI: https://doi.org/10.1158/1078-0432.CCR-09-0227

Published: 15 July 2009

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Journal Articles

Absence of E-Cadherin Expression Distinguishes Noncohesive from Cohesive Pancreatic Cancer

Jordan M. Winter, Angela H. Ting, Felip Vilardell, Eike Gallmeier, Steve B. Baylin, Ralph H. Hruban, Scott E. Kern, Christine A. Iacobuzio-Donahue

Clin Cancer Res (2008) 14 (2): 412–418.

DOI: https://doi.org/10.1158/1078-0432.CCR-07-0487

Published: 25 January 2008

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Journal Articles

Immunohistochemical and Genetic Evaluation of Deoxycytidine Kinase in Pancreatic Cancer: Relationship to Molecular Mechanisms of Gemcitabine Resistance and Survival

Valeria Sebastiani, Francesca Ricci, Belen Rubio-Viquiera, Piotr Kulesza, Charles J. Yeo, Manuel Hidalgo, Alison Klein, Daniel Laheru, Christine A. Iacobuzio-Donahue

Clin Cancer Res (2006) 12 (8): 2492–2497.

DOI: https://doi.org/10.1158/1078-0432.CCR-05-2655

Published: 25 April 2006

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Journal Articles

Increased Cyclooxygenase-2 Expression in Duodenal Compared with Colonic Tissues in Familial Adenomatous Polyposis and Relationship to the −765G → C COX-2 Polymorphism

Lodewijk A.A. Brosens, Christine A. Iacobuzio-Donahue, Josbert J. Keller, Steven R. Hustinx, Ralph Carvalho, Folkert H. Morsink, Linda M. Hylind, G. Johan Offerhaus, Francis M. Giardiello, Michael Goggins

Clin Cancer Res (2005) 11 (11): 4090–4096.

DOI: https://doi.org/10.1158/1078-0432.CCR-04-2379

Published: 01 June 2005

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Journal Articles

MAP2K4/MKK4 Expression in Pancreatic Cancer: Genetic Validation of Immunohistochemistry and Relationship to Disease Course

Wei Xin, Ki J. Yun, Francesca Ricci, Marianna Zahurak, Wanglong Qiu, Gloria H. Su, Charles J. Yeo, Ralph H. Hruban, Scott E. Kern, Christine A. Iacobuzio-Donahue

Clin Cancer Res (2004) 10 (24): 8516–8520.

DOI: https://doi.org/10.1158/1078-0432.CCR-04-0885

Published: 28 December 2004

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NARROW

Initial Whole-Genome Sequencing of Plasma Cell Neoplasms in First Responders and Recovery Workers Exposed to the World Trade Center Attack of September 11, 2001

The Genetic Evolution of Treatment-Resistant Cutaneous, Acral, and Uveal Melanomas

Genomic Methods Identify Homologous Recombination Deficiency in Pancreas Adenocarcinoma and Optimize Treatment Selection

Evaluating Mismatch Repair Deficiency in Pancreatic Adenocarcinoma: Challenges and Recommendations

Real-Time Genomic Profiling of Pancreatic Ductal Adenocarcinoma: Potential Actionability and Correlation with Clinical Phenotype

Transcriptional Mechanisms of Resistance to Anti–PD-1 Therapy

Mutant p53 Together with TGFβ Signaling Influence Organ-Specific Hematogenous Colonization Patterns of Pancreatic Cancer

Cyst Fluid Analysis in Pancreatic Intraductal Papillary Mucinous Neoplasms

Functional p38 MAPK Identified by Biomarker Profiling of Pancreatic Cancer Restrains Growth through JNK Inhibition and Correlates with Improved Survival

Novel Methylation Biomarker Panel for the Early Detection of Pancreatic Cancer

Genetically Defined Subsets of Human Pancreatic Cancer Show Unique In Vitro Chemosensitivity

Clinical Significance of the Genetic Landscape of Pancreatic Cancer and Implications for Identification of Potential Long-term Survivors

CpG Island Methylator Phenotype–Positive Tumors in the Absence of MLH1 Methylation Constitute a Distinct Subset of Duodenal Adenocarcinomas and Are Associated with Poor Prognosis

Genetic Basis of Pancreas Cancer Development and Progression: Insights from Whole-Exome and Whole-Genome Sequencing

Genomic and Epigenomic Integration Identifies a Prognostic Signature in Colon Cancer

SMAD4 Gene Mutations Are Associated with Poor Prognosis in Pancreatic Cancer

Absence of E-Cadherin Expression Distinguishes Noncohesive from Cohesive Pancreatic Cancer

Immunohistochemical and Genetic Evaluation of Deoxycytidine Kinase in Pancreatic Cancer: Relationship to Molecular Mechanisms of Gemcitabine Resistance and Survival

Increased Cyclooxygenase-2 Expression in Duodenal Compared with Colonic Tissues in Familial Adenomatous Polyposis and Relationship to the −765G → C COX-2 Polymorphism

MAP2K4/MKK4 Expression in Pancreatic Cancer: Genetic Validation of Immunohistochemistry and Relationship to Disease Course

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